Snap25 (synaptosome associated protein 25)

Gene: Snap25 (synaptosome associated protein 25) Ictidomys tridecemlineatus

Analyze

Symbol:

Snap25

Name:

synaptosome associated protein 25

RGD ID:

12539048

Description:

ENCODES a protein that exhibits calcium-dependent protein binding (ortholog); lipid binding (ortholog); myosin binding (ortholog); INVOLVED IN associative learning (ortholog); axonogenesis (ortholog); calcium ion-regulated exocytosis of neurotransmitter (ortholog); PARTICIPATES IN insulin secretion pathway; ASSOCIATED WITH Alagille syndrome (ortholog); ALAGILLE SYNDROME 1 (ortholog); attention deficit hyperactivity disorder (ortholog); FOUND IN actin cytoskeleton (ortholog); axonal growth cone (ortholog); BLOC-1 complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

synaptosomal-associated protein 25; synaptosome associated protein 25, transcript variant X1; synaptosome associated protein 25, transcript variant X2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	160,767,380 - 160,848,503 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	9,195,110 - 9,279,920 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	9,198,744 - 9,279,854 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alagille syndrome (ISO)

ALAGILLE SYNDROME 1 (ISO)

attention deficit hyperactivity disorder (ISO)

Bardet-Biedl syndrome (ISO)

bipolar disorder (ISO)

congenital myasthenic syndrome (ISO)

congenital myasthenic syndrome 18 (ISO)

depressive disorder (ISO)

developmental and epileptic encephalopathy (ISO)

developmental and epileptic encephalopathy 12 (ISO)

developmental and epileptic encephalopathy 2 (ISO)

Developmental Disabilities (ISO)

Down syndrome (ISO)

early infantile epileptic encephalopathy (ISO)

epilepsy (ISO)

epilepsy with generalized tonic-clonic seizures (ISO)

Experimental Diabetes Mellitus (ISO)

focal epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

microcephaly (ISO)

Muscle Hypotonia (ISO)

Neurodevelopmental Disorders (ISO)

Neuromuscular Manifestations (ISO)

obesity (ISO)

optic atrophy (ISO)

psychotic disorder (ISO)

schizophrenia (ISO)

stereotypic movement disorder (ISO)

Tics (ISO)

type 2 diabetes mellitus (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

associative learning (IEA,ISO)

axonogenesis (ISO)

calcium ion-regulated exocytosis of neurotransmitter (ISO)

endosomal transport (ISO)

exocytic insertion of neurotransmitter receptor to postsynaptic membrane (IEA)

exocytosis (IEA)

locomotory behavior (IEA,ISO)

long-term memory (ISO)

long-term synaptic potentiation (IEA,ISO)

membrane fusion (IEA)

neuron differentiation (ISO)

neurotransmitter receptor internalization (IEA)

neurotransmitter secretion (IEA,ISO)

positive regulation of hormone secretion (ISO)

positive regulation of insulin secretion (ISO)

potassium ion transmembrane transport (IEA)

presynaptic dense core vesicle exocytosis (IEA)

regulation of establishment of protein localization (IEA,ISO)

regulation of neuron projection development (IEA)

regulation of synapse assembly (ISO)

SNARE complex assembly (ISO)

synaptic vesicle exocytosis (IEA)

synaptic vesicle fusion to presynaptic active zone membrane (IEA)

synaptic vesicle priming (IEA)

Cellular Component

actin cytoskeleton (ISO)

axon (IEA)

axonal growth cone (ISO)

BLOC-1 complex (IEA,ISO)

cell cortex (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

endosome (ISO)

extrinsic component of presynaptic membrane (ISO)

filopodium (ISO)

glutamatergic synapse (IEA,ISO)

growth cone (ISO)

lamellipodium (ISO)

membrane (IEA)

neuron projection (IEA)

neuronal cell body (ISO)

perinuclear region of cytoplasm (IEA)

photoreceptor inner segment (IEA)

plasma membrane (IEA)

postsynapse (IEA)

presynapse (ISO)

presynaptic active zone membrane (ISO)

presynaptic membrane (IEA,ISO)

ribbon synapse (IEA)

SNARE complex (IEA,ISO)

somatodendritic compartment (IEA)

synapse (IEA)

synaptic vesicle (IEA)

synaptobrevin 2-SNAP-25-syntaxin-1a complex (ISO)

synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex (IEA)

synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex (ISO)

trans-Golgi network (IEA)

vesicle (IEA)

voltage-gated potassium channel complex (ISO)

Molecular Function

calcium-dependent protein binding (ISO)

lipid binding (ISO)

myosin binding (ISO)

protein binding (ISO)

protein domain specific binding (ISO)

SNAP receptor activity (IEA)

SNARE binding (IEA,ISO)

syntaxin-1 binding (IEA,ISO)

transmembrane transporter binding (ISO)

voltage-gated potassium channel activity (IEA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

insulin secretion pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Snap25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	160,767,380 - 160,848,503 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936485	9,195,110 - 9,279,920 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936485	9,198,744 - 9,279,854 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SNAP25
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	10,218,830 - 10,307,418 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	10,172,395 - 10,308,258 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	10,199,478 - 10,288,066 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	10,147,477 - 10,236,065 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	10,147,476 - 10,236,065	NCBI
Celera	20	10,269,471 - 10,358,052 (+)	NCBI		Celera
Cytogenetic Map	20	p12.2	NCBI
HuRef	20	10,151,237 - 10,239,826 (+)	NCBI		HuRef
CHM1_1	20	10,200,162 - 10,288,707 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	10,261,695 - 10,350,292 (+)	NCBI		T2T-CHM13v2.0

Snap25
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	136,555,359 - 136,624,348 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	136,555,373 - 136,624,348 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	136,713,439 - 136,782,428 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	136,713,453 - 136,782,428 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	136,539,186 - 136,608,164 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	136,404,944 - 136,473,857 (+)	NCBI		MGSCv36	mm8
Celera	2	137,909,643 - 137,978,489 (+)	NCBI		Celera
Cytogenetic Map	2	F3	NCBI
cM Map	2	67.56	NCBI

Snap25
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	144,494,579 - 144,576,449 (+)	NCBI		GRCr8
mRatBN7.2	3	124,041,898 - 124,123,761 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	124,041,898 - 124,123,760 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	127,931,004 - 128,009,819 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	136,507,987 - 136,586,804 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	134,186,617 - 134,271,659 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	129,697,408 - 129,788,417 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	129,599,353 - 129,788,400 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	136,182,051 - 136,269,422 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	124,806,637 - 124,894,653 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	124,712,177 - 124,800,221 (+)	NCBI
Celera	3	122,761,455 - 122,842,679 (+)	NCBI		Celera
Cytogenetic Map	3	q36	NCBI

Snap25
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955415	20,133,201 - 20,219,023 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955415	20,133,361 - 20,218,840 (+)	NCBI	ChiLan1.0	ChiLan1.0

SNAP25
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	11,089,280 - 11,178,585 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	11,086,107 - 11,175,412 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	10,164,236 - 10,252,856 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	10,164,346 - 10,252,843 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	10,218,358 - 10,252,841 (+)	Ensembl	panpan1.1		panPan2

SNAP25
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	12,003,005 - 12,081,385 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	12,004,117 - 12,081,329 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	11,821,959 - 11,900,304 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	12,414,152 - 12,492,563 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	12,409,789 - 12,492,544 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	12,021,341 - 12,099,876 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	12,120,883 - 12,199,168 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	12,463,988 - 12,542,509 (-)	NCBI		UU_Cfam_GSD_1.0

SNAP25
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	19,141,464 - 19,227,576 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	19,096,115 - 19,227,580 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	21,669,084 - 21,703,714 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SNAP25
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	27,857,093 - 27,944,487 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	27,858,319 - 27,944,496 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	16,634,204 - 16,722,155 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Snap25
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	11,274,490 - 11,302,813 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	11,218,259 - 11,303,406 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005320481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021723156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010003700	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSSTOT00000014167 ⟹ ENSSTOP00000012692

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936485	9,195,110 - 9,279,920 (-)	Ensembl

RefSeq Acc Id:

ENSSTOT00000038858 ⟹ ENSSTOP00000027115

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
SpeTri2.0 Ensembl	NW_004936485	9,195,110 - 9,279,920 (-)	Ensembl

RefSeq Acc Id:

XM_005320481 ⟹ XP_005320538

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	160,767,380 - 160,848,498 (-)	NCBI
SpeTri2.0	NW_004936485	9,198,744 - 9,279,852 (-)	NCBI

Sequence:

show sequence

CTTTGATGAGGGCAGAGCTCACGTTGCATTGAAGACGAAACCTCGGGGAGGTCAGGCGCTGTCT
CTCCTTCCCTCTCTGCACGGTGGCTCCTCCACACTTGCAACCTGCAGGGACTCGGCCAACACCA
CCCTCTGAAGAAGCAAAGGTTCAAAAGCCAAACCCATCACTGACCCCCCAACCCAGGCGCCCAG
CCACCCCCCACCGCTACCATGGCTGAAGACGCCGACATGCGCAATGAGCTGGAGGAGATGCAGC
GGAGGGCTGACCAGTTGGCTGATGAGTCGCTGGAAAGCACCCGTCGTATGCTGCAACTGGTCGA
AGAGAGTAAAGATGCTGGTATCAGGACTTTGGTTATGTTGGATGAACAAGGAGAACAACTGGAA
CGCATTGAGGAAGGGATGGACCAAATCAATAAGGACATGAAAGAAGCAGAAAAGAATTTGACGG
ACCTAGGAAAATTCTGCGGGCTTTGTGTGTGTCCCTGTAACAAGCTTAAATCAAGTGATGCTTA
CAAAAAAGCCTGGGGCAATAATCAGGATGGAGTGGTGGCCAGCCAGCCTGCTCGTGTGGTGGAT
GAACGGGAGCAAATGGCCATCAGTGGTGGCTTCATCCGCAGGGTAACAAATGATGCCCGAGAAA
ATGAAATGGATGAAAACCTGGAGCAGGTGAGCGGCATCATTGGAAACCTCCGTCACATGGCCCT
GGACATGGGCAATGAGATCGATACGCAGAATCGCCAGATCGACAGGATCATGGAGAAGGCTGAT
TCCAACAAAACCAGAATCGATGAGGCCAACCAACGTGCAACAAAGATGCTGGGAAGTGGTTAAA
CGTTCTCAACTGTGCTCTCTTCTGAATGCTGTTGGGCAAGATAGCTCCTTCATGCTTTTCTCAT
GGTATTACCGAGTAGGTCTTGCACATACACACACAGACACACACACGTACACACACACACACAC
ACACACACACACCATCAGTCCACCCCCATCGTAAATGTTGTCCTGTGTCATTTGTCAGCTTTCT
GACAATGCCATATGTCTTTTGTTCTCTGAGTCTCTTTCTTTCCAAAGGTTGTACATAGTGGTCA
TTTAGTGGCTCTAACGCTTTATGTAAGATGTCTTGGGTTTCATTTTCCCTTTTTTTCTCTCTTC
AGTGGCGTTTGCTGAATGACAACAATTTAGGAATGCTCAATGTGCTGTTGATTCTTTCAATACA
CAGTATTGTTCTCGTAAAACTGTGACATTCCACAGAGCTACTGCCACGGTCCTTTCTTTGGGTG
TCAGGCTCTGAATCTCTCAAAATGTGCTGTCTTTAGTTCCTCATGGCTCTTATCTGTCTTTATG
ATTTCATGATTAGACAATGTGGAATTACATAACAGGCATTGCACTAAAAGTGATGTGATTTATG
CATTTATGCATGAGAACTAAATAGATTTTTAGATTCCTACTTAAACAAAAACTTTCCATGACAA
TAGCATACTGATGAGAAAACAACGCACACACACAACACAACAACAACCAACCAACAAAGCATGC
TCAGTATTGAGACACTGTCAAGATTAAGTTATACCAGCAAAACTGCAGTAGTGTCACTTTCTTT
CTGTCGACATATAGACTTTATTAATCATAATCATCCTTTTTTAAAAAAATGAATTTTAAAAAAA
GATGAATTTGACACACTCACCATTCAATCATTTCCAGCAAAATATATGTTTGGCTGAAACTATG
TCAAATGGATGTAATATAGGGTTTGTTTGCTGCTTTTGAAGGCTATGTTTTGGAGAAAATAATC
TTGCTGTGAAACAGTGTGGAGATGTAAATTTTATAAGGCTGACTCTTGTTGATCACCATTTCCC
CTGTGATTCGTTATCAGTACAATTCTTTGTTGCTTAATCTAGAGCTATGCACACCAAAATGCTG
AGATGTTTAGTAGCTGATAAAGAAACCTTTAAAAAATAATATAAATGAATGAAATATAAACTGT
GAGATAAATATCATTACAGCATGTAATATTAAATTCCTCCTGTCTCCTCTGTCGGTTTGTGAAG
TGATTGACATTTTGTAGCTAGTTTAAAATTATTAAAAATTATAGACCCCAGA

hide sequence

RefSeq Acc Id:

XM_021723156 ⟹ XP_021578831

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024408640	160,767,380 - 160,848,503 (-)	NCBI
SpeTri2.0	NW_004936485	9,198,744 - 9,279,854 (-)	NCBI

Sequence:

show sequence

ATCTTTGATGAGGGCAGAGCTCACGTTGCATTGAAGACGAAACCTCGGGGAGGTCAGGCGCTGT
CTCTCCTTCCCTCTCTGCACGGTGGCTCCTCCACACTTGCAACCTGCAGGGACTCGGCCAACAC
CACCCTCTGAAGAAGCAAAGGTTCAAAAGCCAAACCCATCACTGACCCCCCAACCCAGGCGCCC
AGCCACCCCCCACCGCTACCATGGCTGAAGACGCCGACATGCGCAATGAGCTGGAGGAGATGCA
GCGGAGGGCTGACCAGTTGGCTGATGAGTCGCTGGAAAGCACCCGTCGTATGCTGCAACTGGTC
GAAGAGAGTAAAGATGCTGGTATCAGGACTTTGGTTATGTTGGATGAACAAGGAGAACAACTCG
ATCGGGTCGAAGAAGGCATGAACCATATCAACCAAGACATGAAGGAGGCCGAGAAAAATTTAAA
AGATTTAGGGAAATGCTGTGGCCTTTTCATATGTCCTTGTAACAAGCTTAAATCAAGTGATGCT
TACAAAAAAGCCTGGGGCAATAATCAGGATGGAGTGGTGGCCAGCCAGCCTGCTCGTGTGGTGG
ATGAACGGGAGCAAATGGCCATCAGTGGTGGCTTCATCCGCAGGGTAACAAATGATGCCCGAGA
AAATGAAATGGATGAAAACCTGGAGCAGGTGAGCGGCATCATTGGAAACCTCCGTCACATGGCC
CTGGACATGGGCAATGAGATCGATACGCAGAATCGCCAGATCGACAGGATCATGGAGAAGGCTG
ATTCCAACAAAACCAGAATCGATGAGGCCAACCAACGTGCAACAAAGATGCTGGGAAGTGGTTA
AACGTTCTCAACTGTGCTCTCTTCTGAATGCTGTTGGGCAAGATAGCTCCTTCATGCTTTTCTC
ATGGTATTACCGAGTAGGTCTTGCACATACACACACAGACACACACACGTACACACACACACAC
ACACACACACACACCATCAGTCCACCCCCATCGTAAATGTTGTCCTGTGTCATTTGTCAGCTTT
CTGACAATGCCATATGTCTTTTGTTCTCTGAGTCTCTTTCTTTCCAAAGGTTGTACATAGTGGT
CATTTAGTGGCTCTAACGCTTTATGTAAGATGTCTTGGGTTTCATTTTCCCTTTTTTTCTCTCT
TCAGTGGCGTTTGCTGAATGACAACAATTTAGGAATGCTCAATGTGCTGTTGATTCTTTCAATA
CACAGTATTGTTCTCGTAAAACTGTGACATTCCACAGAGCTACTGCCACGGTCCTTTCTTTGGG
TGTCAGGCTCTGAATCTCTCAAAATGTGCTGTCTTTAGTTCCTCATGGCTCTTATCTGTCTTTA
TGATTTCATGATTAGACAATGTGGAATTACATAACAGGCATTGCACTAAAAGTGATGTGATTTA
TGCATTTATGCATGAGAACTAAATAGATTTTTAGATTCCTACTTAAACAAAAACTTTCCATGAC
AATAGCATACTGATGAGAAAACAACGCACACACACAACACAACAACAACCAACCAACAAAGCAT
GCTCAGTATTGAGACACTGTCAAGATTAAGTTATACCAGCAAAACTGCAGTAGTGTCACTTTCT
TTCTGTCGACATATAGACTTTATTAATCATAATCATCCTTTTTTAAAAAAATGAATTTTAAAAA
AAGATGAATTTGACACACTCACCATTCAATCATTTCCAGCAAAATATATGTTTGGCTGAAACTA
TGTCAAATGGATGTAATATAGGGTTTGTTTGCTGCTTTTGAAGGCTATGTTTTGGAGAAAATAA
TCTTGCTGTGAAACAGTGTGGAGATGTAAATTTTATAAGGCTGACTCTTGTTGATCACCATTTC
CCCTGTGATTCGTTATCAGTACAATTCTTTGTTGCTTAATCTAGAGCTATGCACACCAAAATGC
TGAGATGTTTAGTAGCTGATAAAGAAACCTTTAAAAAATAATATAAATGAATGAAATATAAACT
GTGAGATAAATATCATTACAGCATGTAATATTAAATTCCTCCTGTCTCCTCTGTCGGTTTGTGA
AGTGATTGACATTTTGTAGCTAGTTTAAAATTATTAAAAATTATAGACCCCAGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_005320538	(Get FASTA)	NCBI Sequence Viewer
	XP_021578831	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000012692.1
	ENSSTOP00000027115.1
GenBank Protein	KAG3262839	(Get FASTA)	NCBI Sequence Viewer
	KAG3262840	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_005320538 ⟸ XM_005320481
- Peptide Label:	isoform X1
- UniProtKB:	I3MME1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGM DQINKDMKEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMA ISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRI DEANQRATKMLGSG hide sequence

RefSeq Acc Id:	XP_021578831 ⟸ XM_021723156
- Peptide Label:	isoform X2
- UniProtKB:	A0A287D0U1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGM NHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMA ISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRI DEANQRATKMLGSG hide sequence

RefSeq Acc Id:

ENSSTOP00000027115 ⟸ ENSSTOT00000038858

RefSeq Acc Id:

ENSSTOP00000012692 ⟸ ENSSTOT00000014167

Protein Domains

t-SNARE coiled-coil homology

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000014169	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000014167.2	UniProtKB/TrEMBL
	ENSSTOT00000038858.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.110	UniProtKB/TrEMBL
InterPro	SNAP-25	UniProtKB/TrEMBL
	SNAP-25_dom	UniProtKB/TrEMBL
	T_SNARE_dom	UniProtKB/TrEMBL
NCBI Gene	Snap25	ENTREZGENE
PANTHER	PTHR19305:SF5	UniProtKB/TrEMBL
	SYNAPTOSOMAL ASSOCIATED PROTEIN	UniProtKB/TrEMBL
Pfam	SNAP-25	UniProtKB/TrEMBL
PROSITE	T_SNARE	UniProtKB/TrEMBL
SMART	t_SNARE	UniProtKB/TrEMBL
Superfamily-SCOP	SNARE fusion complex	UniProtKB/TrEMBL
UniProt	A0A287D0U1	ENTREZGENE, UniProtKB/TrEMBL
	I3MME1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations