Spta1 (spectrin alpha, erythrocytic 1) - Rat Genome Database

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Gene: Spta1 (spectrin alpha, erythrocytic 1) Ictidomys tridecemlineatus
Analyze
Symbol: Spta1
Name: spectrin alpha, erythrocytic 1
RGD ID: 12538138
Description: ENCODES a protein that exhibits actin filament binding (inferred); calcium ion binding (inferred); metal ion binding (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); hemopoiesis (ortholog); lymphocyte homeostasis (ortholog); ASSOCIATED WITH anemia (ortholog); autoimmune interstitial lung, joint, and kidney disease (ortholog); congenital hemolytic anemia (ortholog); FOUND IN axon (ortholog); cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: spectrin alpha chain, erythrocytic 1; spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050584,995,049 - 5,068,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367401,686,218 - 1,759,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367401,686,218 - 1,759,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Spta1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050584,995,049 - 5,068,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367401,686,218 - 1,759,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367401,686,218 - 1,759,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SPTA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381158,610,704 - 158,686,715 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1158,610,704 - 158,686,715 (-)EnsemblGRCh38hg38GRCh38
GRCh371158,580,494 - 158,656,505 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,847,120 - 156,923,130 (-)NCBINCBI36Build 36hg18NCBI36
Build 341155,393,568 - 155,469,561NCBI
Celera1131,651,547 - 131,727,219 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1129,938,262 - 130,013,934 (-)NCBIHuRef
CHM1_11159,976,850 - 160,052,530 (-)NCBICHM1_1
T2T-CHM13v2.01157,747,803 - 157,823,815 (-)NCBIT2T-CHM13v2.0
Spta1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391174,000,305 - 174,076,015 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1174,000,342 - 174,076,016 (+)EnsemblGRCm39 Ensembl
GRCm381174,172,739 - 174,248,449 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1174,172,776 - 174,248,450 (+)EnsemblGRCm38mm10GRCm38
MGSCv371176,102,907 - 176,178,580 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361176,009,543 - 176,084,742 (+)NCBIMGSCv36mm8
MGSCv361175,481,229 - 175,556,592 (+)NCBIMGSCv36mm8
Celera1181,280,976 - 181,363,312 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.97NCBI
Spta1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81388,735,833 - 88,811,697 (+)NCBIGRCr8
mRatBN7.21386,203,504 - 86,279,371 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1386,203,504 - 86,279,371 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1388,714,968 - 88,786,574 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01390,115,246 - 90,186,848 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01387,299,995 - 87,371,589 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01392,264,231 - 92,340,091 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1392,264,231 - 92,340,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01396,782,387 - 96,860,327 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41389,951,924 - 90,028,592 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11390,140,807 - 90,217,468 (+)NCBI
Celera1385,806,253 - 85,882,378 (+)NCBICelera
Cytogenetic Map13q24NCBI
Spta1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546810,472,671 - 10,545,313 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546810,472,601 - 10,545,402 (-)NCBIChiLan1.0ChiLan1.0
SPTA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2191,161,251 - 91,236,695 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1190,905,096 - 90,980,575 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01133,969,717 - 134,045,301 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11137,760,188 - 137,836,131 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1137,760,942 - 137,835,927 (-)Ensemblpanpan1.1panPan2
SPTA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13823,052,046 - 23,118,933 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3823,051,563 - 23,118,966 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3823,074,219 - 23,141,493 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03823,183,707 - 23,251,018 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3823,183,635 - 23,250,966 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,946,752 - 23,013,687 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03823,481,482 - 23,548,479 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03823,912,752 - 23,979,956 (+)NCBIUU_Cfam_GSD_1.0
SPTA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl491,485,067 - 91,640,063 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1491,573,470 - 91,640,057 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2499,567,778 - 99,634,336 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SPTA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1205,238,246 - 5,314,204 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl205,238,447 - 5,313,887 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660384,407,178 - 4,482,460 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Spta1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247942,639,039 - 2,714,591 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247942,638,605 - 2,715,934 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000015291   ⟹   ENSSTOP00000013701
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367401,686,218 - 1,759,078 (+)Ensembl
RefSeq Acc Id: XM_005339400   ⟹   XP_005339457
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244050584,995,049 - 5,068,389 (-)NCBI
SpeTri2.0NW_0049367401,686,218 - 1,759,083 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040287247   ⟹   XP_040143181
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244050584,995,049 - 5,057,864 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005339457 (Get FASTA)   NCBI Sequence Viewer  
  XP_040143181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000013701.3
GenBank Protein KAG3281008 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005339457   ⟸   XM_005339400
- Peptide Label: isoform X2
- UniProtKB: I3MPI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040143181   ⟸   XM_040287247
- Peptide Label: isoform X1
RefSeq Acc Id: ENSSTOP00000013701   ⟸   ENSSTOT00000015291
Protein Domains
EF-hand   SH3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000015256 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000015291.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  1.20.58.60 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF-hand_Ca_insen UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Spectrin/alpha-actinin UniProtKB/TrEMBL
  Spectrin_repeat UniProtKB/TrEMBL
NCBI Gene Spta1 ENTREZGENE
PANTHER SPECTRIN ALPHA CHAIN, ERYTHROCYTIC 1 UniProtKB/TrEMBL
  SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN UniProtKB/TrEMBL
Pfam EFhand_Ca_insen UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
  Spectrin UniProtKB/TrEMBL
PRINTS SPECTRNALPHA UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART efhand_Ca_insen UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SPEC UniProtKB/TrEMBL
Superfamily-SCOP Spectrin repeat UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF50044 UniProtKB/TrEMBL
UniProt I3MPI0 ENTREZGENE, UniProtKB/TrEMBL