Slc24a3 (solute carrier family 24 member 3) - Rat Genome Database

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Gene: Slc24a3 (solute carrier family 24 member 3) Ictidomys tridecemlineatus
Analyze
Symbol: Slc24a3
Name: solute carrier family 24 member 3
RGD ID: 12520359
Description: ENCODES a protein that exhibits calcium, potassium:sodium antiporter activity (ortholog); INVOLVED IN bone mineralization (ortholog); intracellular calcium ion homeostasis (ortholog); monoatomic cation transport (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); genetic disease (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell periphery (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/potassium/calcium exchanger 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640152,206,337 - 152,654,468 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936485639,532 - 1,085,830 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936485637,715 - 1,085,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc24a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640152,206,337 - 152,654,468 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936485639,532 - 1,085,830 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936485637,715 - 1,085,860 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC24A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382019,212,642 - 19,722,926 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2019,212,642 - 19,722,926 (+)EnsemblGRCh38hg38GRCh38
GRCh372019,193,286 - 19,703,570 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362019,141,290 - 19,651,541 (+)NCBINCBI36Build 36hg18NCBI36
Build 342019,141,289 - 19,651,540NCBI
Celera2019,267,475 - 19,777,636 (+)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2019,155,790 - 19,666,236 (+)NCBIHuRef
CHM1_12019,262,244 - 19,704,077 (+)NCBICHM1_1
T2T-CHM13v2.02019,264,159 - 19,774,968 (+)NCBIT2T-CHM13v2.0
Slc24a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392145,009,695 - 145,484,086 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2145,009,674 - 145,484,086 (+)EnsemblGRCm39 Ensembl
GRCm382145,167,775 - 145,642,166 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2145,167,754 - 145,642,166 (+)EnsemblGRCm38mm10GRCm38
MGSCv372145,068,347 - 145,467,689 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362144,934,052 - 145,333,394 (+)NCBIMGSCv36mm8
Celera2146,442,567 - 146,852,275 (+)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.08NCBI
Slc24a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83153,005,418 - 153,504,497 (+)NCBIGRCr8
mRatBN7.23132,552,119 - 133,051,192 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3132,551,595 - 133,051,192 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3136,458,426 - 136,960,748 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03145,042,522 - 145,544,835 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03142,745,677 - 143,247,999 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03139,333,942 - 139,835,728 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3139,695,028 - 139,833,967 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03145,760,074 - 146,259,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43133,734,890 - 134,249,326 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13133,640,575 - 134,153,200 (+)NCBI
Celera3131,419,773 - 131,916,131 (+)NCBICelera
Cytogenetic Map3q41NCBI
Slc24a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541527,477,819 - 27,928,383 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541527,477,801 - 27,930,108 (+)NCBIChiLan1.0ChiLan1.0
SLC24A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22120,097,895 - 20,610,669 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12020,094,738 - 20,607,505 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02019,168,820 - 19,680,706 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12019,137,943 - 19,648,235 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2019,137,938 - 19,646,475 (+)Ensemblpanpan1.1panPan2
SLC24A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1243,593,562 - 4,014,366 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl243,593,513 - 3,784,467 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha243,620,103 - 3,818,880 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0244,000,491 - 4,482,100 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl244,000,493 - 4,482,430 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1243,595,752 - 4,077,406 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0243,699,250 - 4,181,348 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,977,410 - 4,458,938 (-)NCBIUU_Cfam_GSD_1.0
SLC24A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1727,270,093 - 27,780,526 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11727,270,232 - 27,780,535 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21731,405,580 - 31,468,072 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC24A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1248,238,872 - 48,736,517 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660783,017,793 - 3,516,931 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc24a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474119,808,255 - 20,297,056 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474119,808,186 - 20,298,772 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013356476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010003700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000009824   ⟹   ENSSTOP00000008810
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_004936485639,532 - 1,085,830 (-)Ensembl
RefSeq Acc Id: XM_013356476   ⟹   XP_013211930
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024408640152,206,337 - 152,654,468 (-)NCBI
SpeTri2.0NW_004936485637,715 - 1,085,860 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013211930 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008810.3
GenBank Protein KAG3262777 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_013211930   ⟸   XM_013356476
- UniProtKB: I3MEA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000008810   ⟸   ENSSTOT00000009824
Protein Domains
Sodium/calcium exchanger membrane region


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009809 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009824.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1420.30 UniProtKB/TrEMBL
InterPro K/Na/Ca-exchanger UniProtKB/TrEMBL
  NaCa_Exmemb UniProtKB/TrEMBL
  NCX_ion-bd_dom_sf UniProtKB/TrEMBL
NCBI Gene Slc24a3 ENTREZGENE
PANTHER PTHR10846 UniProtKB/TrEMBL
  SODIUM/POTASSIUM/CALCIUM EXCHANGER 3 UniProtKB/TrEMBL
Pfam Na_Ca_ex UniProtKB/TrEMBL
UniProt I3MEA6 ENTREZGENE, UniProtKB/TrEMBL