Tardbp (TAR DNA binding protein) - Rat Genome Database

Name: Tardbp
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Tardbp (TAR DNA binding protein) Ictidomys tridecemlineatus

Analyze

Symbol:

Tardbp

Name:

TAR DNA binding protein

RGD ID:

12517854

Description:

ENCODES a protein that exhibits DNA binding (ortholog); double-stranded DNA binding (ortholog); identical protein binding (ortholog); INVOLVED IN 3'-UTR-mediated mRNA destabilization (ortholog); 3'-UTR-mediated mRNA stabilization (ortholog); amyloid fibril formation (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); amyotrophic lateral sclerosis (ortholog); amyotrophic lateral sclerosis type 1 (ortholog); FOUND IN interchromatin granule (ortholog); intracellular non-membrane-bounded organelle (ortholog); nuclear speck (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

LOC101975729; TAR DNA binding protein, transcript variant X1; TAR DNA binding protein, transcript variant X10; TAR DNA binding protein, transcript variant X7; TAR DNA binding protein, transcript variant X8; TAR DNA-binding protein 43

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

SpeTri2.0 - Squirrel SpeTri2.0 Assembly

Position:

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936474	90,813 - 103,713 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

amyotrophic lateral sclerosis (ISO)

amyotrophic lateral sclerosis type 1 (ISO)

amyotrophic lateral sclerosis type 10 (ISO)

Brain Injuries (ISO)

Charcot-Marie-Tooth disease type 2 (ISO)

chromosome 1p36 deletion syndrome (ISO)

Chronic Brain Injury (ISO)

Cognitive Dysfunction (ISO)

Familial Atrial Fibrillation 6 (ISO)

frontotemporal dementia (ISO)

Frontotemporal Lobar Degeneration (ISO)

genetic disease (ISO)

immunodeficiency 14 (ISO)

Lewy body dementia (ISO)

MASP2 Deficiency (ISO)

motor neuron disease (ISO)

neurodegenerative disease (ISO)

Parkinson's disease (ISO)

Peroxisome Biogenesis Disorder, Complementation Group K (ISO)

Pick's disease (ISO)

progressive supranuclear palsy (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

3'-UTR-mediated mRNA destabilization (ISO)

3'-UTR-mediated mRNA stabilization (ISO)

amyloid fibril formation (ISO)

gene expression (ISO)

mRNA processing (IEA)

negative regulation by host of viral transcription (ISO)

negative regulation of gene expression (ISO)

negative regulation of protein phosphorylation (ISO)

nuclear inner membrane organization (ISO)

positive regulation of insulin secretion (ISO)

positive regulation of protein import into nucleus (ISO)

regulation of apoptotic process (ISO)

regulation of cell cycle (ISO)

regulation of circadian rhythm (ISO)

regulation of gene expression (IEA)

regulation of protein stability (ISO)

response to endoplasmic reticulum stress (ISO)

RNA splicing (IEA,ISO)

Cellular Component

interchromatin granule (ISO)

intracellular non-membrane-bounded organelle (ISO)

nuclear speck (ISO)

nucleoplasm (IEA)

nucleus (IEA)

perichromatin fibrils (ISO)

Molecular Function

DNA binding (ISO)

double-stranded DNA binding (ISO)

identical protein binding (ISO)

lipid binding (ISO)

molecular condensate scaffold activity (ISO)

mRNA 3'-UTR binding (ISO)

pre-mRNA intronic binding (ISO)

protein binding (ISO)

RNA binding (IEA,ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Tardbp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936474	90,813 - 103,713 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TARDBP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	11,012,654 - 11,030,528 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	11,012,344 - 11,030,528 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	11,072,711 - 11,085,549 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	10,995,266 - 11,008,136 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	11,006,944 - 11,019,814	NCBI
Celera	1	10,184,976 - 10,197,861 (+)	NCBI		Celera
Cytogenetic Map	1	p36.22	NCBI
HuRef	1	10,224,341 - 10,237,229 (+)	NCBI		HuRef
CHM1_1	1	11,060,321 - 11,073,209 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	10,553,914 - 10,571,805 (+)	NCBI		T2T-CHM13v2.0

Tardbp
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	148,696,839 - 148,711,672 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	148,696,839 - 148,711,476 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	148,612,382 - 148,627,084 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	148,612,382 - 148,627,019 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	147,986,491 - 148,001,105 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	147,454,416 - 147,470,796 (-)	NCBI		MGSCv36	mm8
Celera	4	150,873,662 - 150,888,313 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	78.77	NCBI

Tardbp
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	164,330,452 - 164,348,435 (-)	NCBI		GRCr8
mRatBN7.2	5	159,050,518 - 159,062,218 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	159,051,799 - 159,062,055 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	161,768,493 - 161,778,784 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	163,590,953 - 163,601,242 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	163,547,298 - 163,557,588 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	165,432,089 - 165,442,232 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	165,432,095 - 165,442,048 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	169,088,684 - 169,099,216 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	165,698,665 - 165,709,531 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	165,708,851 - 165,719,708 (-)	NCBI
Celera	5	157,327,910 - 157,337,955 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Tardbp
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	2,656,121 - 2,674,807 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	2,656,121 - 2,674,808 (-)	NCBI	ChiLan1.0	ChiLan1.0

TARDBP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	217,200,843 - 217,212,563 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	215,840,309 - 215,858,530 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	9,775,084 - 9,786,710 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	10,996,006 - 11,008,732 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	10,996,006 - 11,008,732 (+)	Ensembl	panpan1.1		panPan2

TARDBP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	84,987,752 - 84,998,136 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	84,989,952 - 84,998,593 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	81,515,040 - 81,527,435 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	85,647,107 - 85,659,313 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	85,649,924 - 85,659,763 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	82,395,167 - 82,407,547 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	83,396,611 - 83,408,986 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	84,459,460 - 84,471,855 (-)	NCBI		UU_Cfam_GSD_1.0

TARDBP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	71,213,860 - 71,227,704 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	71,213,584 - 71,227,707 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	65,135,826 - 65,147,430 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TARDBP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	120,753,764 - 120,765,259 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	24,661,891 - 24,675,297 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tardbp
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	1,759,497 - 1,789,813 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	1,759,496 - 1,789,806 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005317442	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363836	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013363839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_040287921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001230130	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001230132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002485073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002485074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002485075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002485076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005734948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005734949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005734950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAESOR010000117	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_040287921 ⟹ XP_040143855

Type:

CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,274,946 (+)	NCBI

RefSeq Acc Id:

XR_001230130

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI
SpeTri2.0	NW_004936474	90,813 - 98,956 (+)	NCBI

Sequence:

show sequence

AGTTAAAAGTCTGCGCGTCCGTATTTTTTTTCAGTCTCTAATTTTTCAGGCCCAGGTGTTGGTC
TTATTGTAGCATTTAAATCTTCTCTCCTCACGCTGGGACTCCCAGCAGGGCGCCCAGCCCGCGG
AGGAGAAGGTCCTGGCGTCTTGGCGCGGCGCCCTCCCCCTCTTGACCCGGAGCCGGTGGGAGAG
GACGACGGCCGGCGGGGGGGGGAGGAGGCGGCTCTAGCGCCATTTTGTGGGAACGTAGAGGTAG
CTGGGCTGCTCTCGGATCCCTCGCTGCTTCAGTTTCGGTGTCGCGCTTCCTAGCAGCGGCCTAG
CGGAGAAGTAAGAAGAGATGTCTGAATATATTCGGGTAACGGAAGATGAGAATGATGAGCCCAT
TGAAATACCATCAGAAGATGATGGGACAGTGCTGCTGTCCACAGTTACAGCCCAGTTTCCAGGG
GCATGTGGGCTGCGCTACAGGAATCCAGTGACCCAGTGTATGAGAGGTGTTCGCCTAGTAGAAG
GAATTCTGCATGCCCCTGATGCTGGTTGGGGAAACCTGGTATATGTTGTCAACTATCCCAAAGA
TAACAAAAGGAAAATGGATGAGACAGATGCTTCATCGGCAGTGAAAGTGAAAAGAGCAGTCCAA
AAAACATCTGATTTAATAGTATTGGGTCTCCCATGGAAAACAACCGAACAGGACCTGAAAGAGT
ATTTTAGTACTTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATATTAAAACTGGTCATTC
AAAAGGGTTTGGCTTTGTACGATTTACGGAATATGAAACCCAGGTGAAAGTAATGTCACAGCGA
CATATGATAGATGGACGATGGTGTGACTGTAAACTCCCCAATTCTAAGCAAAGCCCGGATGAGC
CTTTGAGAAGCAGAAAGGTGTTTGTTGGGCGCTGTACAGAGGACATGACTGCTGATGAGCTGCA
GCAGTTCTTCTGTCAGTATGGAGAAGTGGTAGATGTCTTCATTCCCAAACCATTCAGGGCTTTT
GCCTTTGTTACATTTGCAGATGATCAGGTTGCCCAGTCTCTTTGTGGAGAGGACTTGATCATTA
AAGGAATCAGCGTGCATATATCCAATGCTGAACCTAAGCACAATAGCAATAGGCAGTTAGAGAG
AAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGGTTTGGTAACAGTAGA
GGGGGTGGAGCTGGCTTGGGAAACAATCAGGGTAGTAACATGGGTGGAGGGATGAACTTTGGTG
CTTTTAGCATTAATCCAGCAATGATGGCAGCAGCCCAGGCAGCGCTGCAGAGCAGTTGGGGTAT
GATGAGCATGTTAGCCAGTCAGCAGAACCAGTCAGGCCCATCAGGTAATAACCAAAGCCAGGGC
AACATGCAGAGAGAGCCAAATCAAGCTTTTGGGTCTGGAAATAATTCCTATAGTGGTTCTAATT
CTGGTGCTGCAATTGGTTGGGGATCAGCATCAAATGCAGGGTCAGGTAGTGGTTTCAATGGAGG
CTTTGGCTCAAGCATGGATTCTAAATCTTCTGGCTGGGGAATGTAGATAGTGGGTTATGGTTGG
TTAGTTAGAATGGTGGAAATTCAAATTTTTCTAAACTCATGGTAAGTATATTGTAAAATACATA
TGTACTAAGAATTTTCAAAATTGGTTTGTTCAGTGTGGAGTATATTCAGCAGTATTTTTGACAT
TTTTCTTTAGAAAAAGAGGAAGAGCTAAAGGAATTTTATAAGTTTTGTTACATAAAGGGTTGAA
ATATTGAGTGGTTGAAAGTGAATTGCTGTTTGCCTGATTGGTAAACCAACACACTACAATTGAT
ATCTAAAAGGTTTCTCCTGTAATGTTTTATCCCTGGACTTGTTAAGTGAATTCTTTGCATGTTC
AAAGTGGAAACCATTGATTAGAACTACATTCTTTTCTCCTTTTTTAATTTGAACCCCACCATAT
GGATTTTTTCCTTAGGAAAATCTCCTTTTGGGAGATCATGGTGTCACAGTGTTTGGTTCTTTTG
GTTTTGTTTTTTAACACTTGTCTCCTCTCATATACAAAAGTACAATATGAAGCCTTCATTTAAT
CTCTGCAGTTCATCTCATTTCAAATGTTTATGGAAGAAGCACTTCATTGAAAGTAGTGCTGTAA
ATATTCTGCCATAGGAATGCTTCTGTCTACATGCTTTCTCATTCAAGAATTCGTCATCACGCTG
CACAGGCTGCGTCTTTGACGCCCTGAATGCAAAGAATTCATAGCAGTTAATTCCCCTTTTTTGA
CCCTTTTGAGATGGAACTTTCATAAAGTTTCTTGGCAGTAGTTTATTTTGCTTCAAATAAACTT
ATTTGAAAAGTTGT

hide sequence

RefSeq Acc Id:

XR_002485075

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI
SpeTri2.0	NW_004936474	90,813 - 100,193 (+)	NCBI

Sequence:

show sequence

AGTTAAAAGTCTGCGCGTCCGTATTTTTTTTCAGTCTCTAATTTTTCAGGCCCAGGTGTTGGTC
TTATTGTAGCATTTAAATCTTCTCTCCTCACGCTGGGACTCCCAGCAGGGCGCCCAGCCCGCGG
AGGAGAAGGTCCTGGCGTCTTGGCGCGGCGCCCTCCCCCTCTTGACCCGGAGCCGGTGGGAGAG
GACGACGGCCGGCGGGGGGGGGAGGAGGCGGCTCTAGCGCCATTTTGTGGGAACGTAGAGGTAG
CTGGGCTGCTCTCGGATCCCTCGCTGCTTCAGTTTCGGTGTCGCGCTTCCTAGCAGCGGCCTAG
CGGAGAAGTAAGAAGAGATGTCTGAATATATTCGGGTAACGGAAGATGAGAATGATGAGCCCAT
TGAAATACCATCAGAAGATGATGGGACAGTGCTGCTGTCCACAGTTACAGCCCAGTTTCCAGGG
GCATGTGGGCTGCGCTACAGGAATCCAGTGACCCAGTGTATGAGAGGTGTTCGCCTAGTAGAAG
GAATTCTGCATGCCCCTGATGCTGGTTGGGGAAACCTGGTATATGTTGTCAACTATCCCAAAGA
TAACAAAAGGAAAATGGATGAGACAGATGCTTCATCGGCAGTGAAAGTGAAAAGAGCAGTCCAA
AAAACATCTGATTTAATAGTATTGGGTCTCCCATGGAAAACAACCGAACAGGACCTGAAAGAGT
ATTTTAGTACTTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATATTAAAACTGGTCATTC
AAAAGGGTTTGGCTTTGTACGATTTACGGAATATGAAACCCAGGTGAAAGTAATGTCACAGCGA
CATATGATAGATGGACGATGGTGTGACTGTAAACTCCCCAATTCTAAGCAAAGCCCGGATGAGC
CTTTGAGAAGCAGAAAGGTGTTTGTTGGGCGCTGTACAGAGGACATGACTGCTGATGAGCTGCA
GCAGTTCTTCTGTCAGTATGGAGAAGTGGTAGATGTCTTCATTCCCAAACCATTCAGGGCTTTT
GCCTTTGTTACATTTGCAGATGATCAGGTTGCCCAGTCTCTTTGTGGAGAGGACTTGATCATTA
AAGGAATCAGCGTGCATATATCCAATGCTGAACCTAAGCACAATAGCAATAGGCAGTTAGAGAG
AAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGGTTTGGTAACAGTAGA
GGGGGTGGAGCTGGCTTGGGAAACAATCAGGGTAGTAACATGGGTGGAGGGATGAACTTTGGTG
CTTTTAGCATTAATCCAGCAATGATGGCAGCAGCCCAGGCAGCGCTGCAGAGCAGTTGGGGTAT
GATGAGCATGTTAGCCAGTCAGCAGAACCAGTCAGGCCCATCAGGTAATAACCAAAGCCAGGGC
AACATGCAGAGAGAGCCAAATCAAGCTTTTGGGTCTGGAAATAATTCCTATAGTGGTTCTAATT
CTGGTGCTGCAATTGGTTGGGGATCAGCATCAAATGCAGGGTCAGGTAGTGGTTTCAATGGAGG
CTTTGGCTCAAGCATGGATTCTAAATCTTCTGGCTGGGGAATGTAGATAGTGGGTTATGGTTGG
TTAGTTAGAATGGTGGAAATTCAAATTTTTCTAAACTCATGGTAAGTATATTGTAAAATACATA
TGTACTAAGAATTTTCAAAATTGGTTTGTTCAGTGTGGAGTATATTCAGCAGTATTTTTGACAT
TTTTCTTTAGAAAAAGAGGAAGAGCTAAAGGAATTTTATAAGTTTTGTTACATAAAGGGTTGAA
ATATTGAGTGGTTGAAAGTGAATTGCTGTTTGCCTGATTGGTAAACCAACACACTACAATTGAT
ATCTAAAAGGTTTCTCCTGTAATGTTTTATCCCTGGACTTGTTAAGTGAATTCTTTGCATGTTC
AAAGTGGAAACCATTGATTAGAACTACATTCTTTTCTCCTTTTTTAATTTGAACCCCACCATAT
GGATTTTTTCCTTAGGAAAATCTCCTTTTGGGAGATCATGGTGTCACAGTGTTTGGTTCTTTTG
GTTTTGTTTTTTAACACTTGTCTCCTCTCATATACAAAAGTACAATATGAAGCCTTCATTTAAT
CTCTGCAGTTCATCTCATTTCAAATGTTTATGGAAGAAGCACTTCATTGAAAGTAGTGCTGTAA
ATATTCTGCCATAGGAATGCTTCTGTCTACATGCTTTCTCATTCAAGAATTCGTCATCACGCTG
CACAGGCTGCGTCTTTGACGTTTTTAATAAGTCTGGGTGACCGCACCTAAAATGCACTTGCACT
ATTACTCAGCAGCAGTAACATGGTAACACTTAAAATGGTATTCGGGGACCTCCAAAGACTAAAC
TGACAAGCCTTCAAGGAGCCCAGGGGTAAGTTAACTTATCGATGGCATGGTTTTAATACCTTAT
TTACACTTGTTAAAGCTAGTTGCTGGTCATAGAAGGCTTTCAATGTTGAGTAGCCTTTTATTTA
ACATGTTTATGATACTACATAGTGGGTAGTTATTCTGCCCTTTAAAAAAAAATTAAAGTTTAGA
AGTACTTAAACTATTTGGCAAAGATTTGTT

hide sequence

RefSeq Acc Id:

XR_002485076

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI
SpeTri2.0	NW_004936474	90,813 - 100,193 (+)	NCBI

Sequence:

show sequence

AGTTAAAAGTCTGCGCGTCCGTATTTTTTTTCAGTCTCTAATTTTTCAGGCCCAGGTGTTGGTC
TTATTGTAGCATTTAAATCTTCTCTCCTCACGCTGGGACTCCCAGCAGGGCGCCCAGCCCGCGG
AGGAGAAGGTCCTGGCGTCTTGGCGCGGCGCCCTCCCCCTCTTGACCCGGAGCCGGTGGGAGAG
GACGACGGCCGGCGGGGGGGGGAGGAGGCGGCTCTAGCGCCATTTTGTGGGAACGTAGAGGTAG
CTGGGCTGCTCTCGGATCCCTCGCTGCTTCAGTTTCGGTGTCGCGCTTCCTAGCAGCGGCCTAG
CGGAGAAGTAAGAAGAGATGTCTGAATATATTCGGGTAACGGAAGATGAGAATGATGAGCCCAT
TGAAATACCATCAGAAGATGATGGGACAGTGCTGCTGTCCACAGTTACAGCCCAGTTTCCAGGG
GCATGTGGGCTGCGCTACAGGAATCCAGTGACCCAGTGTATGAGAGGTGTTCGCCTAGTAGAAG
GAATTCTGCATGCCCCTGATGCTGGTTGGGGAAACCTGGTATATGTTGTCAACTATCCCAAAGA
TAACAAAAGGAAAATGGATGAGACAGATGCTTCATCGGCAGTGAAAGTGAAAAGAGCAGTCCAA
AAAACATCTGATTTAATAGTATTGGGTCTCCCATGGAAAACAACCGAACAGGACCTGAAAGAGT
ATTTTAGTACTTTTGGAGAAGTTCTTATGGTGCAGGTCAAGAAAGATATTAAAACTGGTCATTC
AAAAGGGTTTGGCTTTGTACGATTTACGGAATATGAAACCCAGGTGAAAGTAATGTCACAGCGA
CATATGATAGATGGACGATGGTGTGACTGTAAACTCCCCAATTCTAAGCAAAGCCCGGATGAGC
CTTTGAGAAGCAGAAAGGTGTTTGTTGGGCGCTGTACAGAGGACATGACTGCTGATGAGCTGCA
GCAGTTCTTCTGTCAGTATGGAGAAGTGGTAGATGTCTTCATTCCCAAACCATTCAGGGCTTTT
GCCTTTGTTACATTTGCAGATGATCAGGTTGCCCAGTCTCTTTGTGGAGAGGACTTGATCATTA
AAGGAATCAGCGTGCATATATCCAATGCTGAACCTAAGCACAATAGCAATAGGCAGTTAGAGAG
AAGTGGAAGATTTGGTGGTAATCCAGGTGGCTTTGGGAATCAGGGTGGGTTTGGTAACAGTAGA
GGGGGTGGAGCTGGCTTGGGAAACAATCAGGGTAGTAACATGGGTGGAGGGATGAACTTTGGTG
CTTTTAGCATTAATCCAGCAATGATGGCAGCAGCCCAGGCAGCGCTGCAGAGCAGTTGGGGTAT
GATGAGCATGTTAGCCAGTCAGCAGAACCAGTCAGGCCCATCAGGTAATAACCAAAGCCAGGGC
AACATGCAGAGAGAGCCAAATCAAGCTTTTGGGTCTGGAAATAATTCCTATAGTGGTTCTAATT
CTGGTGCTGCAATTGGTTGGGGATCAGCATCAAATGCAGGGTCAGGTAGTGGTTTCAATGGAGG
CTTTGGCTCAAGCATGGATTCTAAATCTTCTGGCTGGGGAATGTAGATAGTGGGTTATGGTTGG
TTAGTTAGAATGGTGGAAATTCAAATTTTTCTAAACTCATGGTAAGTATATTGTAAAATACATA
TGTACTAAGAATTTTCAAAATTGGTTTGTTCAGTGTGGAGTATATTCAGCAGTATTTTTGACAT
TTTTCTTTAGAAAAAGAGGAAGAGCTAAAGGAATTTTATAAGTTTTGTTACATAAAGGGTTGAA
ATATTGAGTGGTTGAAAGTGAATTGCTGTTTGCCTGATTGGTAAACCAACACACTACAATTGAT
ATCTAAAAGGTTTCTCCTGTAATGTTTTATCCCTGGACTTGTTAAGTGAATTCTTTGCATGTTC
AAAGTGGAAACCATTGATTAGAACTACATTCTTTTCTCCTTTTTTAATTTGAACCCCACCATAT
GGATTTTTTCCTTAGGAAAATCTCCTTTTGGGAGATCATGGTGTCACAGTGTTTGGTTCTTTTG
GTTTTGTTTTTTAACACTTGTCTCCTCTCATATACAAAAGTACAATATGAAGCCTTCATTTAAT
CTCTGCAGTTCATCTCATTTCAAATGTTTATGGAAGAAGCACTTCATTGAAAGTAGTGCTGTAA
ATATTCTGCCATAGGAATGCTTCTGTCTACATGCTTTCTCATTCAAGAATTCGTCATCACGCTG
CACAGGCTGCGTCTTTGACGCACTTGCACTATTACTCAGCAGCAGTAACATGGTAACACTTAAA
ATGGTATTCGGGGACCTCCAAAGACTAAACTGACAAGCCTTCAAGGAGCCCAGGGGTAAGTTAA
CTTATCGATGGCATGGTTTTAATACCTTATTTACACTTGTTAAAGCTAGTTGCTGGTCATAGAA
GGCTTTCAATGTTGAGTAGCCTTTTATTTAACATGTTTATGATACTACATAGTGGGTAGTTATT
CTGCCCTTTAAAAAAAAATTAAAGTTTAGAAGTACTTAAACTATTTGGCAAAGATTTGTT

hide sequence

RefSeq Acc Id:

XR_005734948

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI

RefSeq Acc Id:

XR_005734949

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI

RefSeq Acc Id:

XR_005734950

Type:

NON-CODING

Position:

Squirrel Assembly	Chr	Position (strand)	Source
HiC_Itri_2	NW_024405058	34,266,198 - 34,278,928 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_040143855	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSTOP00000024248.1
	ENSSTOP00000029907.1
GenBank Protein	KAG3282133	(Get FASTA)	NCBI Sequence Viewer
	KAG3282134	(Get FASTA)	NCBI Sequence Viewer
	KAG3282135	(Get FASTA)	NCBI Sequence Viewer
	KAG3282136	(Get FASTA)	NCBI Sequence Viewer
	KAG3282137	(Get FASTA)	NCBI Sequence Viewer
	KAG3282138	(Get FASTA)	NCBI Sequence Viewer
	KAG3282139	(Get FASTA)	NCBI Sequence Viewer
	KAG3282140	(Get FASTA)	NCBI Sequence Viewer
	KAG3282141	(Get FASTA)	NCBI Sequence Viewer
	KAG3282142	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

XP_040143855 ⟸ XM_040287921

Protein Domains

RRM

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSTOG00000008406	UniProtKB/TrEMBL
Ensembl Transcript	ENSSTOT00000030366.1	UniProtKB/TrEMBL
	ENSSTOT00000034573.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.70.330	UniProtKB/TrEMBL
InterPro	Nucleotide-bd_a/b_plait_sf	UniProtKB/TrEMBL
	RBD_domain_sf	UniProtKB/TrEMBL
	RRM_dom	UniProtKB/TrEMBL
	TDP43_N	UniProtKB/TrEMBL
NCBI Gene	Tardbp	ENTREZGENE
PANTHER	RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN	UniProtKB/TrEMBL
	TAR DNA-BINDING PROTEIN 43	UniProtKB/TrEMBL
Pfam	RRM_1	UniProtKB/TrEMBL
	TDP43_N	UniProtKB/TrEMBL
PROSITE	RRM	UniProtKB/TrEMBL
SMART	RRM	UniProtKB/TrEMBL
Superfamily-SCOP	SSF54928	UniProtKB/TrEMBL
UniProt	A0A287CSL0_ICTTR	UniProtKB/TrEMBL
	A0A287D8L2_ICTTR	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-08-09	Tardbp	TAR DNA binding protein	LOC101975729	TAR DNA binding protein	Symbol and/or name change	5135510	APPROVED
2021-03-26	LOC101975729	TAR DNA binding protein	Tardbp	TAR DNA binding protein	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM