Dcc (DCC netrin 1 receptor) - Rat Genome Database

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Gene: Dcc (DCC netrin 1 receptor) Ictidomys tridecemlineatus
Analyze
Symbol: Dcc
Name: DCC netrin 1 receptor
RGD ID: 12514275
Description: ENCODES a protein that exhibits identical protein binding (ortholog); netrin receptor activity (ortholog); transcription coactivator activity (ortholog); INVOLVED IN anterior/posterior axon guidance (ortholog); axon development (ortholog); axon guidance (ortholog); ASSOCIATED WITH Agenesis of Corpus Callosum (ortholog); amenorrhea (ortholog); autism spectrum disorder (ortholog); FOUND IN axon (ortholog); growth cone membrane (ortholog); postsynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DCC netrin 1 receptor, transcript variant X1; DCC netrin 1 receptor, transcript variant X2; DCC netrin 1 receptor, transcript variant X3; DCC netrin 1 receptor, transcript variant X4; deleted in colorectal carcinoma; netrin receptor DCC
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494434,878,291 - 35,930,900 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649710,122,617 - 11,169,803 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dcc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494434,878,291 - 35,930,900 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649710,122,617 - 11,169,803 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381852,340,197 - 53,535,899 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1852,340,197 - 53,535,899 (+)EnsemblGRCh38hg38GRCh38
GRCh371849,866,567 - 51,062,269 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361848,120,569 - 49,311,780 (+)NCBINCBI36Build 36hg18NCBI36
Build 341848,121,155 - 49,311,286NCBI
Celera1846,722,385 - 47,918,339 (+)NCBICelera
Cytogenetic Map18q21.2NCBI
HuRef1846,722,887 - 47,917,133 (+)NCBIHuRef
CHM1_11849,861,521 - 51,057,237 (+)NCBICHM1_1
T2T-CHM13v2.01852,543,078 - 53,739,020 (+)NCBIT2T-CHM13v2.0
Dcc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391871,386,703 - 72,484,299 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1871,386,705 - 72,484,140 (-)EnsemblGRCm39 Ensembl
GRCm381871,253,613 - 72,351,228 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1871,253,634 - 72,351,069 (-)EnsemblGRCm38mm10GRCm38
MGSCv371871,413,286 - 72,510,723 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361871,384,359 - 72,475,947 (-)NCBIMGSCv36mm8
Celera1872,536,536 - 73,631,393 (-)NCBICelera
Cytogenetic Map18E2NCBI
cM Map1845.24NCBI
Dcc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81867,144,272 - 68,248,159 (-)NCBIGRCr8
mRatBN7.21864,868,987 - 65,972,783 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1864,873,898 - 65,972,740 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1866,947,462 - 68,060,043 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01867,635,044 - 68,751,656 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01865,475,745 - 66,586,354 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01866,518,213 - 67,629,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1866,523,120 - 67,224,566 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01865,688,901 - 66,793,126 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41868,026,795 - 69,140,741 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11868,099,995 - 69,213,942 (-)NCBI
Celera1862,907,666 - 64,001,277 (-)NCBICelera
Cytogenetic Map18q12.1-q12.2NCBI
Dcc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540237,123,795 - 38,218,472 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540237,123,112 - 38,218,876 (+)NCBIChiLan1.0ChiLan1.0
DCC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21769,864,630 - 71,059,880 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11855,557,246 - 56,752,486 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01845,717,924 - 46,913,998 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11849,060,454 - 50,255,116 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1849,268,812 - 50,255,155 (+)Ensemblpanpan1.1panPan2
DCC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,788,833 - 22,494,849 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,793,328 - 22,494,967 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,784,245 - 23,871,211 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,687,171 - 22,774,992 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,688,158 - 22,774,948 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,742,849 - 22,829,651 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,635,199 - 22,721,696 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,906,717 - 22,993,897 (-)NCBIUU_Cfam_GSD_1.0
DCC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1101,846,100 - 103,083,096 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11101,518,629 - 103,087,021 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21112,538,098 - 112,878,669 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DCC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11827,437,224 - 28,623,717 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1827,442,489 - 28,212,697 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660501,432,122 - 2,644,336 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477815,979,467 - 17,222,039 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477815,979,350 - 17,225,263 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000003593   ⟹   ENSSTOP00000003219
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_00493649710,122,617 - 11,169,803 (-)Ensembl
RefSeq Acc Id: XM_005323057   ⟹   XP_005323114
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,898 (-)NCBI
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005323058   ⟹   XP_005323115
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,898 (-)NCBI
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725006   ⟹   XP_021580681
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,898 (-)NCBI
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021725007   ⟹   XP_021580682
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,898 (-)NCBI
SpeTri2.0NW_00493649710,122,078 - 11,169,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040273020   ⟹   XP_040128954
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,898 (-)NCBI
RefSeq Acc Id: XM_040273028   ⟹   XP_040128962
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494434,878,291 - 35,930,900 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005323114   ⟸   XM_005323057
- Peptide Label: isoform X1
- UniProtKB: I3M2K2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005323115   ⟸   XM_005323058
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_021580682   ⟸   XM_021725007
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_021580681   ⟸   XM_021725006
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_040128962   ⟸   XM_040273028
- Peptide Label: isoform X6
RefSeq Acc Id: XP_040128954   ⟸   XM_040273020
- Peptide Label: isoform X4
RefSeq Acc Id: ENSSTOP00000003219   ⟸   ENSSTOT00000003593
Protein Domains
Fibronectin type-III   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003557 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003593.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Neogenin_C UniProtKB/TrEMBL
NCBI Gene Dcc ENTREZGENE
PANTHER PROTEIN SIDEKICK UniProtKB/TrEMBL
  PTHR44170:SF8 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Neogenin_C UniProtKB/TrEMBL
PRINTS FNTYPEIII UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt I3M2K2 ENTREZGENE, UniProtKB/TrEMBL