Lpin1 (lipin 1) - Rat Genome Database

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Gene: Lpin1 (lipin 1) Ictidomys tridecemlineatus
Analyze
Symbol: Lpin1
Name: lipin 1
RGD ID: 12504513
Description: ENCODES a protein that exhibits histone deacetylase binding (ortholog); peroxisome proliferator activated receptor binding (ortholog); RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); animal organ regeneration (ortholog); cellular lipid metabolic process (ortholog); PARTICIPATES IN mTOR signaling pathway; ASSOCIATED WITH Acute Recurrent Myoglobinuria, Autosomal Recessive (ortholog); Cachexia (ortholog); end stage renal disease (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lipin 1, transcript variant X1; lipin 1, transcript variant X2; lipin 1, transcript variant X3; lipin 1, transcript variant X4; phosphatidate phosphatase LPIN1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,788,616 - 52,899,844 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365327,605,965 - 7,652,573 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365327,596,279 - 7,654,139 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Lpin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629252,788,616 - 52,899,844 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365327,605,965 - 7,652,573 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365327,596,279 - 7,654,139 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LPIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38211,677,544 - 11,827,409 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl211,677,595 - 11,827,409 (+)EnsemblGRCh38hg38GRCh38
GRCh37211,817,670 - 11,967,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,804,191 - 11,884,986 (+)NCBINCBI36Build 36hg18NCBI36
Build 34211,837,337 - 11,918,129NCBI
Celera211,803,878 - 11,884,673 (+)NCBICelera
Cytogenetic Map2p25.1NCBI
HuRef211,669,235 - 11,818,856 (+)NCBIHuRef
CHM1_1211,747,316 - 11,897,077 (+)NCBICHM1_1
T2T-CHM13v2.0211,710,702 - 11,860,525 (+)NCBIT2T-CHM13v2.0
Lpin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391216,585,670 - 16,697,020 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1216,585,670 - 16,696,967 (-)EnsemblGRCm39 Ensembl
GRCm381216,535,669 - 16,653,903 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1216,535,669 - 16,646,966 (-)EnsemblGRCm38mm10GRCm38
MGSCv371216,542,475 - 16,596,576 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361216,562,116 - 16,615,250 (-)NCBIMGSCv36mm8
Celera1216,861,042 - 16,914,762 (-)NCBICelera
Cytogenetic Map12A1.1NCBI
cM Map127.9NCBI
Lpin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8645,039,110 - 45,145,845 (-)NCBIGRCr8
mRatBN7.2639,309,198 - 39,417,034 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl639,312,748 - 39,417,097 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx639,644,137 - 39,711,411 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0639,958,820 - 40,026,103 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0639,392,085 - 39,459,366 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0641,796,214 - 41,905,149 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl641,799,749 - 41,870,046 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0651,532,422 - 51,638,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4640,253,664 - 40,297,195 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1640,292,340 - 40,300,145 (-)NCBI
Celera638,623,057 - 38,690,436 (-)NCBICelera
Cytogenetic Map6q16NCBI
Lpin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554876,138,926 - 6,210,012 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554876,139,188 - 6,207,316 (+)NCBIChiLan1.0ChiLan1.0
LPIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212114,699,681 - 114,850,433 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A114,703,663 - 114,854,404 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A11,664,727 - 11,815,497 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A11,847,419 - 11,961,551 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A11,857,961 - 11,961,551 (+)Ensemblpanpan1.1panPan2
LPIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1178,348,860 - 8,480,447 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl178,348,886 - 8,478,863 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha178,279,917 - 8,411,687 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0178,451,896 - 8,584,013 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl178,451,917 - 8,584,010 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1178,382,241 - 8,466,963 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0178,340,808 - 8,472,566 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0178,359,796 - 8,491,836 (+)NCBIUU_Cfam_GSD_1.0
LPIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3124,940,561 - 125,074,122 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13124,940,557 - 125,074,137 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23133,660,296 - 133,740,965 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap3q21-q27NCBI
LPIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11495,777,976 - 95,926,420 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1495,780,478 - 95,926,419 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604516,446,229 - 16,526,834 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lpin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248654,219,081 - 4,258,448 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248654,220,047 - 4,258,014 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000010856   ⟹   ENSSTOP00000009738
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365327,605,965 - 7,652,573 (+)Ensembl
RefSeq Acc Id: ENSSTOT00000041950   ⟹   ENSSTOP00000030284
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365327,605,965 - 7,652,573 (+)Ensembl
RefSeq Acc Id: XM_021727784   ⟹   XP_021583459
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,850,910 - 52,899,844 (+)NCBI
SpeTri2.0NW_0049365327,605,956 - 7,654,139 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040271295   ⟹   XP_040127229
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,815,293 - 52,899,844 (+)NCBI
RefSeq Acc Id: XM_040271296   ⟹   XP_040127230
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,815,293 - 52,899,844 (+)NCBI
RefSeq Acc Id: XM_040271297   ⟹   XP_040127231
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,788,616 - 52,899,844 (+)NCBI
RefSeq Acc Id: XM_040271298   ⟹   XP_040127232
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,788,616 - 52,899,844 (+)NCBI
RefSeq Acc Id: XM_040271299   ⟹   XP_040127233
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,848,119 - 52,899,844 (+)NCBI
RefSeq Acc Id: XM_040271300   ⟹   XP_040127234
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440629252,788,616 - 52,899,844 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021583459   ⟸   XM_021727784
- Peptide Label: isoform X2
- UniProtKB: I3MG83 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040127231   ⟸   XM_040271297
- Peptide Label: isoform X4
- UniProtKB: I3MG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127232   ⟸   XM_040271298
- Peptide Label: isoform X5
- UniProtKB: I3MG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127234   ⟸   XM_040271300
- Peptide Label: isoform X7
- UniProtKB: A0A287D9S0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127229   ⟸   XM_040271295
- Peptide Label: isoform X1
- UniProtKB: I3MG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127230   ⟸   XM_040271296
- Peptide Label: isoform X3
- UniProtKB: A0A287D9S0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040127233   ⟸   XM_040271299
- Peptide Label: isoform X6
- UniProtKB: I3MG83 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000030284   ⟸   ENSSTOT00000041950
RefSeq Acc Id: ENSSTOP00000009738   ⟸   ENSSTOT00000010856
Protein Domains
LNS2/PITP


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000010854 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000010856.3 UniProtKB/TrEMBL
  ENSSTOT00000041950.1 UniProtKB/TrEMBL
InterPro HAD-like_sf UniProtKB/TrEMBL
  LIPIN UniProtKB/TrEMBL
  Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
  LNS2/PITP UniProtKB/TrEMBL
NCBI Gene Lpin1 ENTREZGENE
PANTHER PTHR12181 UniProtKB/TrEMBL
  PTHR12181:SF10 UniProtKB/TrEMBL
Pfam Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
SMART LNS2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56784 UniProtKB/TrEMBL
UniProt A0A287D9S0 ENTREZGENE, UniProtKB/TrEMBL
  I3MG83 ENTREZGENE, UniProtKB/TrEMBL