P2rx3 (purinergic receptor P2X 3) - Rat Genome Database

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Gene: P2rx3 (purinergic receptor P2X 3) Ictidomys tridecemlineatus
Analyze
Symbol: P2rx3
Name: purinergic receptor P2X 3
RGD ID: 12441116
Description: ENCODES a protein that exhibits ATP binding (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN behavioral response to formalin induced pain (ortholog); behavioral response to pain (ortholog); chemical synaptic transmission (ortholog); ASSOCIATED WITH genetic disease (ortholog); Hyperalgesia (ortholog); intellectual disability (ortholog); FOUND IN dendritic spine (ortholog); hippocampal mossy fiber to CA3 synapse (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: P2X purinoceptor 3; purinergic receptor P2X, ligand-gated ion channel, 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494715,002,140 - 15,032,591 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365815,115,492 - 5,146,634 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365815,116,276 - 5,146,378 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
P2rx3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494715,002,140 - 15,032,591 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365815,115,492 - 5,146,634 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365815,116,276 - 5,146,378 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381157,335,950 - 57,372,396 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1157,338,352 - 57,372,396 (+)EnsemblGRCh38hg38GRCh38
GRCh371157,105,826 - 57,139,869 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361156,862,525 - 56,894,125 (+)NCBINCBI36Build 36hg18NCBI36
Build 341156,862,524 - 56,894,125NCBI
Celera1154,464,979 - 54,477,411 (+)NCBICelera
Cytogenetic Map11q12.1NCBI
HuRef1153,454,728 - 53,486,434 (+)NCBIHuRef
CHM1_11156,971,953 - 57,003,678 (+)NCBICHM1_1
T2T-CHM13v2.01157,285,441 - 57,321,889 (+)NCBIT2T-CHM13v2.0
P2rx3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39284,826,893 - 84,867,446 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl284,828,927 - 84,867,806 (-)EnsemblGRCm39 Ensembl
GRCm38284,996,549 - 85,037,108 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl284,998,583 - 85,037,462 (-)EnsemblGRCm38mm10GRCm38
MGSCv37284,836,709 - 84,875,991 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36284,797,391 - 84,836,673 (-)NCBIMGSCv36mm8
Celera286,595,241 - 86,634,592 (-)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.45NCBI
P2rx3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8390,487,506 - 90,531,315 (-)NCBIGRCr8
mRatBN7.2370,080,850 - 70,124,664 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl370,080,851 - 70,125,178 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx373,462,764 - 73,506,383 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0382,061,439 - 82,105,058 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0379,819,891 - 79,863,521 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0372,403,992 - 72,447,801 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl372,403,993 - 72,447,801 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0378,914,029 - 78,958,459 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4368,228,045 - 68,270,751 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1368,124,416 - 68,167,123 (-)NCBI
Celera369,431,850 - 69,475,670 (-)NCBICelera
Cytogenetic Map3q24NCBI
P2rx3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555112,389,717 - 2,411,008 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555112,389,717 - 2,410,968 (+)NCBIChiLan1.0ChiLan1.0
P2RX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2958,492,901 - 58,531,132 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11159,509,857 - 59,548,082 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01152,579,190 - 52,614,329 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13160,070,860 - 160,104,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3160,070,875 - 160,106,120 (+)Ensemblpanpan1.1panPan2
P2RX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11838,773,930 - 38,801,217 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1838,772,529 - 38,802,057 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1838,319,548 - 38,346,782 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01839,455,279 - 39,482,558 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1839,453,201 - 39,482,831 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11839,035,826 - 39,065,122 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01838,609,330 - 38,638,605 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01839,242,142 - 39,269,413 (-)NCBIUU_Cfam_GSD_1.0
P2RX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl213,584,925 - 13,617,785 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1213,584,913 - 13,619,652 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2213,347,685 - 13,381,122 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P2RX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1115,872,124 - 15,906,452 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666038113,214,882 - 113,249,218 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
P2rx3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248643,229,979 - 3,253,094 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248643,233,019 - 3,253,525 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000008544   ⟹   ENSSTOP00000007658
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365815,118,423 - 5,146,190 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000031583   ⟹   ENSSTOP00000025148
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365815,115,492 - 5,146,634 (-)Ensembl
RefSeq Acc Id: XM_005331595   ⟹   XP_005331652
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,616 - 15,032,591 (-)NCBI
SpeTri2.0NW_0049365815,116,276 - 5,146,378 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040284336   ⟹   XP_040140270
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,616 - 15,031,736 (-)NCBI
RefSeq Acc Id: XM_040284337   ⟹   XP_040140271
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,616 - 15,026,178 (-)NCBI
RefSeq Acc Id: XR_005733505
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,140 - 15,031,736 (-)NCBI
RefSeq Acc Id: XR_005733506
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,616 - 15,031,736 (-)NCBI
RefSeq Acc Id: XR_005733507
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494715,002,616 - 15,031,736 (-)NCBI
Protein Sequences
Protein RefSeqs XP_005331652 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140270 (Get FASTA)   NCBI Sequence Viewer  
  XP_040140271 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000007658.3
  ENSSTOP00000025148.1
GenBank Protein KAG3285067 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005331652   ⟸   XM_005331595
- Peptide Label: isoform X2
- UniProtKB: A0A287CV55 (UniProtKB/TrEMBL),   I3MBT7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040140270   ⟸   XM_040284336
- Peptide Label: isoform X1
RefSeq Acc Id: XP_040140271   ⟸   XM_040284337
- Peptide Label: isoform X3
- UniProtKB: I3MBT7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000007658   ⟸   ENSSTOT00000008544
RefSeq Acc Id: ENSSTOP00000025148   ⟸   ENSSTOT00000031583


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008540 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008544.3 UniProtKB/TrEMBL
  ENSSTOT00000031583.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.490.10 UniProtKB/TrEMBL
  atp-gated p2x4 ion channel UniProtKB/TrEMBL
InterPro P2X3_purnocptor UniProtKB/TrEMBL
  P2X_extracellular_dom_sf UniProtKB/TrEMBL
  P2X_purnocptor UniProtKB/TrEMBL
NCBI Gene P2rx3 ENTREZGENE
PANTHER P2X PURINOCEPTOR UniProtKB/TrEMBL
  PTHR10125:SF8 UniProtKB/TrEMBL
Pfam P2X_receptor UniProtKB/TrEMBL
PIRSF P2X_purinoceptor UniProtKB/TrEMBL
PRINTS P2X3RECEPTOR UniProtKB/TrEMBL
  P2XRECEPTOR UniProtKB/TrEMBL
PROSITE P2X_RECEPTOR UniProtKB/TrEMBL
UniProt A0A287CV55 ENTREZGENE, UniProtKB/TrEMBL
  I3MBT7 ENTREZGENE, UniProtKB/TrEMBL