Kcnc4 (potassium voltage-gated channel subfamily C member 4) - Rat Genome Database

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Gene: Kcnc4 (potassium voltage-gated channel subfamily C member 4) Ictidomys tridecemlineatus
Analyze
Symbol: Kcnc4
Name: potassium voltage-gated channel subfamily C member 4
RGD ID: 12439346
Description: ENCODES a protein that exhibits voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential (ortholog); voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential (ortholog); INVOLVED IN axon development (ortholog); cerebral cortex development (ortholog); corpus callosum development (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); autistic disorder (ortholog); developmental and epileptic encephalopathy 32 (ortholog); FOUND IN axon (ortholog); calyx of Held (ortholog); cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel, Shaw-related subfamily, member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505818,424,809 - 18,446,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367041,667,387 - 1,689,348 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367041,667,387 - 1,689,337 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505818,424,809 - 18,446,759 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367041,667,387 - 1,689,348 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367041,667,387 - 1,689,337 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381110,210,314 - 110,284,080 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1110,210,314 - 110,283,100 (+)EnsemblGRCh38hg38GRCh38
GRCh371110,752,936 - 110,776,666 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361110,555,588 - 110,578,189 (+)NCBINCBI36Build 36hg18NCBI36
Build 341110,466,018 - 110,478,710NCBI
Celera1109,000,516 - 109,023,855 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1108,625,031 - 108,648,390 (+)NCBIHuRef
CHM1_11110,868,669 - 110,892,012 (+)NCBICHM1_1
T2T-CHM13v2.01110,225,284 - 110,300,705 (+)NCBIT2T-CHM13v2.0
Kcnc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393107,345,614 - 107,367,617 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3107,345,619 - 107,366,868 (-)EnsemblGRCm39 Ensembl
GRCm383107,438,298 - 107,460,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3107,438,303 - 107,459,552 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,241,221 - 107,261,816 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363107,566,359 - 107,586,954 (-)NCBIMGSCv36mm8
Celera3109,770,042 - 109,791,022 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.83NCBI
Kcnc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82197,747,095 - 197,788,467 (-)NCBIGRCr8
mRatBN7.22195,063,967 - 195,100,244 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,071,769 - 195,099,233 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2202,720,130 - 202,740,385 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02200,602,290 - 200,622,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02195,419,233 - 195,439,487 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,220,908 - 210,241,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,220,908 - 210,241,455 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02229,694,932 - 229,732,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2187,727,839 - 187,748,108 (-)NCBICelera
Cytogenetic Map2q34NCBI
Kcnc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543513,728,708 - 13,750,660 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543513,728,272 - 13,750,420 (+)NCBIChiLan1.0ChiLan1.0
KCNC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21116,703,093 - 116,828,565 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11115,952,375 - 115,976,166 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01112,860,887 - 112,884,687 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11127,457,895 - 127,480,954 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,458,968 - 127,480,182 (-)Ensemblpanpan1.1panPan2
KCNC4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1641,743,214 - 41,764,572 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl641,738,653 - 41,764,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha644,496,309 - 44,541,283 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0642,051,239 - 42,096,226 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl642,075,855 - 42,096,111 (-)EnsemblROS_Cfam_1.0 Ensembl
UNSW_CanFamBas_1.0641,742,375 - 41,787,313 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0642,177,396 - 42,222,420 (-)NCBIUU_Cfam_GSD_1.0
KCNC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4109,885,116 - 109,908,476 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14109,885,116 - 109,908,518 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24120,280,838 - 120,310,013 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12023,241,279 - 23,328,175 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2023,304,679 - 23,327,382 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603835,131,024 - 35,168,004 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcnc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247725,967,071 - 5,991,484 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247725,967,042 - 6,004,647 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSSTOT00000009640   ⟹   ENSSTOP00000008649
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049367041,667,387 - 1,689,348 (+)Ensembl
RefSeq Acc Id: XM_021735152   ⟹   XP_021590827
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505818,424,809 - 18,446,759 (-)NCBI
SpeTri2.0NW_0049367041,667,387 - 1,689,337 (+)NCBI
Sequence:
RefSeq Acc Id: XM_040287421   ⟹   XP_040143355
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505818,424,809 - 18,446,759 (-)NCBI
RefSeq Acc Id: XM_040287422   ⟹   XP_040143356
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440505818,424,809 - 18,446,759 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021590827 (Get FASTA)   NCBI Sequence Viewer  
  XP_040143355 (Get FASTA)   NCBI Sequence Viewer  
  XP_040143356 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000008649.3
GenBank Protein KAG3281301 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021590827   ⟸   XM_021735152
- Peptide Label: isoform X2
- UniProtKB: I3MDY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040143356   ⟸   XM_040287422
- Peptide Label: isoform X3
- UniProtKB: I3MDY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_040143355   ⟸   XM_040287421
- Peptide Label: isoform X1
- UniProtKB: I3MDY0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000008649   ⟸   ENSSTOT00000009640
Protein Domains
Ion transport


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000009645 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000009640.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv3 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene Kcnc4 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY C MEMBER 4 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam Ion_trans UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
  SHAWCHANNEL UniProtKB/TrEMBL
Superfamily-SCOP Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt I3MDY0 ENTREZGENE, UniProtKB/TrEMBL