TAFA2 (TAFA chemokine like family member 2) - Rat Genome Database

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Gene: TAFA2 (TAFA chemokine like family member 2) Canis lupus familiaris
Analyze
Symbol: TAFA2
Name: TAFA chemokine like family member 2
RGD ID: 12423468
Description: ENCODES a protein that exhibits receptor ligand activity (inferred); INVOLVED IN memory (ortholog); visual learning (ortholog); ASSOCIATED WITH anxiety disorder (ortholog); Cognitive Dysfunction (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: chemokine-like protein TAFA-2; FAM19A2; family with sequence similarity 19 (chemokine (C-C motif)-like), member A2; family with sequence similarity 19 member A2, C-C motif chemokine like; protein FAM19A2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1104,998,538 - 5,134,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl104,999,695 - 5,233,553 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha105,029,406 - 5,395,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0105,024,533 - 5,480,189 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl105,024,537 - 5,161,178 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1104,978,740 - 5,421,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0105,221,674 - 5,670,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0105,361,721 - 5,810,250 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
TAFA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1104,998,538 - 5,134,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl104,999,695 - 5,233,553 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha105,029,406 - 5,395,616 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0105,024,533 - 5,480,189 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl105,024,537 - 5,161,178 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1104,978,740 - 5,421,639 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0105,221,674 - 5,670,753 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0105,361,721 - 5,810,250 (-)NCBIUU_Cfam_GSD_1.0
TAFA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381261,708,273 - 62,260,034 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1261,708,273 - 62,279,150 (-)EnsemblGRCh38hg38GRCh38
GRCh371262,102,054 - 62,586,554 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361260,388,307 - 60,872,818 (-)NCBINCBI36Build 36hg18NCBI36
Build 341260,388,309 - 60,872,818NCBI
Celera1261,771,461 - 62,255,544 (-)NCBICelera
Cytogenetic Map12q14.1NCBI
HuRef1259,153,030 - 59,637,513 (-)NCBIHuRef
CHM1_11262,069,825 - 62,554,522 (-)NCBICHM1_1
T2T-CHM13v2.01261,687,128 - 62,238,817 (-)NCBIT2T-CHM13v2.0
Tafa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910123,099,813 - 123,577,109 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10123,099,901 - 123,577,109 (+)EnsemblGRCm39 Ensembl
GRCm3810123,264,024 - 123,741,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10123,263,996 - 123,741,204 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710122,701,132 - 123,178,035 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610122,667,136 - 123,144,039 (+)NCBIMGSCv36mm8
Celera10125,646,982 - 126,120,933 (+)NCBICelera
Cytogenetic Map10D2NCBI
cM Map1072.31NCBI
Tafa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8760,827,985 - 61,303,873 (+)NCBIGRCr8
mRatBN7.2758,942,598 - 59,418,640 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl758,942,610 - 59,417,299 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0766,017,066 - 66,496,690 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl766,017,086 - 66,172,360 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0766,221,368 - 66,695,803 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4763,388,665 - 63,566,226 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera756,114,065 - 56,588,451 (+)NCBICelera
Cytogenetic Map7q22NCBI
Tafa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554588,935,792 - 9,351,358 (-)NCBIChiLan1.0ChiLan1.0
TAFA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21032,090,348 - 32,637,163 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11232,087,212 - 32,633,940 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01226,683,045 - 27,229,772 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11226,954,142 - 27,501,208 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1227,225,154 - 27,502,300 (+)Ensemblpanpan1.1panPan2
Tafa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494553,173,603 - 53,593,123 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936545517,005 - 701,058 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936545517,910 - 936,630 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAFA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl526,391,996 - 26,557,852 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1526,391,969 - 26,893,517 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2528,995,477 - 29,036,460 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TAFA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11157,598,179 - 58,095,527 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1157,597,697 - 57,763,149 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037187,714,293 - 188,247,361 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tafa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248026,104,788 - 6,275,915 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248025,682,672 - 6,275,081 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TAFA2
1399 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 1 7 4 6 8 3 1
Below cutoff 4 2 11 2 1 2 2 5 7 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000046239   ⟹   ENSCAFP00000042142
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl104,999,695 - 5,233,553 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845013536   ⟹   ENSCAFP00845010504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl105,024,537 - 5,161,178 (-)Ensembl
RefSeq Acc Id: XM_038487962   ⟹   XP_038343890
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1104,978,740 - 5,421,639 (-)NCBI
RefSeq Acc Id: XM_038487963   ⟹   XP_038343891
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1104,978,740 - 5,378,734 (-)NCBI
RefSeq Acc Id: XM_038549855   ⟹   XP_038405783
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0105,361,721 - 5,810,250 (-)NCBI
RefSeq Acc Id: XM_038549856   ⟹   XP_038405784
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0105,361,721 - 5,766,702 (-)NCBI
RefSeq Acc Id: XM_038613824   ⟹   XP_038469752
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0105,221,674 - 5,670,753 (-)NCBI
RefSeq Acc Id: XM_038613825   ⟹   XP_038469753
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0105,221,674 - 5,627,243 (-)NCBI
RefSeq Acc Id: XM_038632210   ⟹   XP_038488138
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha105,029,406 - 5,395,616 (-)NCBI
RefSeq Acc Id: XM_038679179   ⟹   XP_038535107
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0105,024,533 - 5,480,189 (-)NCBI
RefSeq Acc Id: XM_038679180   ⟹   XP_038535108
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0105,024,533 - 5,437,272 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000042142   ⟸   ENSCAFT00000046239
RefSeq Acc Id: XP_038343890   ⟸   XM_038487962
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038343891   ⟸   XM_038487963
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038469752   ⟸   XM_038613824
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038469753   ⟸   XM_038613825
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038535107   ⟸   XM_038679179
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z1H6 (UniProtKB/TrEMBL),   A0A8I3MXB8 (UniProtKB/TrEMBL),   A0A8P0PJ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038535108   ⟸   XM_038679180
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z1H6 (UniProtKB/TrEMBL),   A0A8I3MXB8 (UniProtKB/TrEMBL),   A0A8P0PJ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038488138   ⟸   XM_038632210
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038405783   ⟸   XM_038549855
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z1H6 (UniProtKB/TrEMBL),   A0A8I3MXB8 (UniProtKB/TrEMBL),   A0A8P0PJ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038405784   ⟸   XM_038549856
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Z1H6 (UniProtKB/TrEMBL),   A0A8I3MXB8 (UniProtKB/TrEMBL),   A0A8P0PJ22 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845010504   ⟸   ENSCAFT00845013536


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000032565 Ensembl
  ENSCAFG00000056562 UniProtKB/TrEMBL
  ENSCAFG00030004696 UniProtKB/TrEMBL
  ENSCAFG00040018463 UniProtKB/TrEMBL
  ENSCAFG00845007686 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000103558.1 UniProtKB/TrEMBL
  ENSCAFT00000107051.1 UniProtKB/TrEMBL
  ENSCAFT00030008639.1 UniProtKB/TrEMBL
  ENSCAFT00040034090.1 UniProtKB/TrEMBL
  ENSCAFT00845013536 ENTREZGENE
  ENSCAFT00845013536.1 UniProtKB/TrEMBL
InterPro Chemokine-like_TAFA UniProtKB/TrEMBL
NCBI Gene FAM19A2 ENTREZGENE
PANTHER CHEMOKINE-LIKE PROTEIN TAFA FAMILY MEMBER UniProtKB/TrEMBL
  CHEMOKINE-LIKE PROTEIN TAFA-2 UniProtKB/TrEMBL
Pfam TAFA UniProtKB/TrEMBL
UniProt A0A8C0Z1H6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MXB8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PJ22 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PKA0_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40647 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-22 TAFA2  TAFA chemokine like family member 2  FAM19A2  family with sequence similarity 19 member A2, C-C motif chemokine like  Symbol and/or name change 5135510 APPROVED