RORC (RAR related orphan receptor C)

Gene: RORC (RAR related orphan receptor C) Canis lupus familiaris

Analyze

Symbol:

RORC

Name:

RAR related orphan receptor C

RGD ID:

12421811

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription coactivator binding (ortholog); INVOLVED IN adipose tissue development (ortholog); alpha-beta T cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATED WITH advanced sleep phase syndrome (ortholog); Animal Toxoplasmosis (ortholog); bacterial pneumonia (ortholog); FOUND IN external side of plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

nuclear receptor ROR-gamma

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	60,821,498 - 60,842,485 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	60,821,981 - 60,842,453 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	60,263,366 - 60,285,188 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	61,838,557 - 61,860,379 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	61,837,962 - 61,860,343 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	60,665,332 - 60,687,158 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	60,751,477 - 60,773,308 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	61,480,593 - 61,502,436 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

advanced sleep phase syndrome (ISO)

Animal Toxoplasmosis (ISO)

bacterial pneumonia (ISO)

Dysbiosis (ISO)

Experimental Autoimmune Myocarditis (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

immunodeficiency 42 (ISO)

Inflammation (ISO)

MHC class II deficiency (ISO)

parathyroid carcinoma (ISO)

severe congenital neutropenia 3 (ISO)

severe congenital neutropenia 5 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adipose tissue development (ISO)

alpha-beta T cell differentiation (ISO)

cell differentiation (ISO)

cellular response to sterol (IEA)

circadian regulation of gene expression (ISO)

circadian rhythm (ISO)

intracellular receptor signaling pathway (IEA)

lymph node development (ISO)

mucosa-associated lymphoid tissue development (ISO)

negative regulation of thymocyte apoptotic process (ISO)

negative regulation of transcription by RNA polymerase II (IEA)

Peyer's patch development (ISO)

positive regulation of circadian rhythm (ISO)

positive regulation of DNA-templated transcription (ISO)

regulation of DNA-templated transcription (IEA)

regulation of fat cell differentiation (ISO)

regulation of gamma-delta T cell differentiation (ISO)

regulation of gene expression (IEA)

regulation of glucose metabolic process (ISO)

regulation of steroid metabolic process (ISO)

regulation of transcription by RNA polymerase II (ISO)

T cell differentiation in thymus (ISO)

T-helper 17 cell differentiation (ISO)

T-helper cell differentiation (ISO)

xenobiotic metabolic process (ISO)

Cellular Component

external side of plasma membrane (ISO)

nuclear body (IEA)

nucleus (IEA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IEA)

ligand-activated transcription factor activity (IEA)

metal ion binding (IEA)

nuclear receptor activity (IEA)

oxysterol binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IEA)

sequence-specific DNA binding (IEA)

sequence-specific double-stranded DNA binding (IEA)

transcription coactivator binding (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

RORC
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	60,821,498 - 60,842,485 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	60,821,981 - 60,842,453 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	60,263,366 - 60,285,188 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	61,838,557 - 61,860,379 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	61,837,962 - 61,860,343 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	60,665,332 - 60,687,158 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	60,751,477 - 60,773,308 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	61,480,593 - 61,502,436 (-)	NCBI		UU_Cfam_GSD_1.0

RORC
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	151,806,071 - 151,831,802 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	151,806,071 - 151,831,845 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	151,778,547 - 151,804,278 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	150,045,171 - 150,070,972 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	148,591,621 - 148,617,421	NCBI
Celera	1	124,893,230 - 124,919,042 (-)	NCBI		Celera
Cytogenetic Map	1	q21.3	NCBI
HuRef	1	123,155,515 - 123,181,337 (-)	NCBI		HuRef
CHM1_1	1	153,173,871 - 153,199,672 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	150,929,559 - 150,955,307 (-)	NCBI		T2T-CHM13v2.0

Rorc
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	94,280,106 - 94,305,583 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	94,280,101 - 94,305,583 (+)	Ensembl		GRCm39 Ensembl
GRCm38	3	94,372,794 - 94,398,276 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	94,372,794 - 94,398,276 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	94,176,748 - 94,202,161 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	94,458,190 - 94,483,992 (+)	NCBI		MGSCv36	mm8
Celera	3	95,819,177 - 95,843,048 (+)	NCBI		Celera
Cytogenetic Map	3	F2.1	NCBI
cM Map	3	40.56	NCBI

Rorc
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	184,698,779 - 184,723,942 (+)	NCBI		GRCr8
mRatBN7.2	2	182,009,707 - 182,034,910 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	182,009,286 - 182,034,907 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	2	195,612,471 - 195,636,797 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	195,617,021 - 195,637,630 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
RGSC_v3.4	2	189,345,134 - 189,369,442 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	174,560,165 - 174,584,474 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

Rorc
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955589	590,743 - 616,694 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955589	590,653 - 616,784 (+)	NCBI	ChiLan1.0	ChiLan1.0

RORC
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	97,991,871 - 98,017,622 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	97,743,055 - 97,768,831 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	127,164,725 - 127,190,479 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	130,808,705 - 130,834,490 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	130,808,705 - 130,834,490 (-)	Ensembl	panpan1.1		panPan2

Rorc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	22,967,256 - 22,990,222 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936580	1,997,640 - 2,020,649 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936580	1,997,640 - 2,020,649 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

RORC
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	97,375,136 - 97,400,209 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	97,374,672 - 97,399,017 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	106,397,490 - 106,421,980 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RORC
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	11,854,911 - 11,880,221 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	11,855,005 - 11,879,717 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	11,414,109 - 11,440,149 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Rorc
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624772	19,477,093 - 19,501,169 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624772	19,478,403 - 19,501,184 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in RORC
295 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium			6	6		6	1	5
Low	5	5	13		3		5	1	10		10	4
Below cutoff			3		3				2	8		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005630825	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005630826	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038423216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038423217	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038423218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038453350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038499702	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038562273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038626366	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038626367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038626368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000035	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000359	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000020479 ⟹ ENSCAFP00000019006

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	60,821,981 - 60,842,453 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000079712 ⟹ ENSCAFP00000047912

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	17	60,821,981 - 60,837,574 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845044385 ⟹ ENSCAFP00845034781

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	61,837,962 - 61,860,343 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845044500 ⟹ ENSCAFP00845034868

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	17	61,837,962 - 61,855,473 (-)	Ensembl

RefSeq Acc Id:

XM_005630825 ⟹ XP_005630882

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	60,821,498 - 60,842,485 (-)	NCBI
Dog10K_Boxer_Tasha	17	60,263,366 - 60,285,188 (-)	NCBI

Sequence:

show sequence

CCTCCCTCCCCTGGGCCCTGCTCCCTGCCCTCCTGGGCAGCCAGGGCAGCAAGGACGGCACCCA
GGGAGCTGCCCCATGGACAGGGCCCCACAGAGACAGCACCGAGCCTCGCAGGAGCTGCTGGCTG
CCAAGAAGACCCACACCTCACAAATCGAAGTGATTCCTTGCAAAATCTGTGGAGACAAGTCATC
TGGGATCCACTACGGGGTGATCACCTGTGAGGGATGCAAGGGTTTCTTCCGCCGGAGCCAGCAG
TGTAACGTGGTCTACTCCTGCACCCGCCAGCAGAACTGCCCCATCGACCGCACCAGCCGAAACC
GATGTCAACACTGCCGCCTGCAGAAATGCCTGGCACTGGGCATGTCCCGAGATGCTGTCAAGTT
CGGCCGCATGTCCAAGAAGCAGAGGGACAGCCTGCACGCCGAGGTGCAGAAACAGCTGCAGCGG
CAGCAACAGCAGCAGCGAGGACAGGTGGCCAAGACCCCACCAGCGGGGGGCCAGGGAGCTGACC
CCCTCGCCTGCCCCATAGGGCTCCCAGATGGGCAGCTGCCCCTGGGCTCATCACCTGACCTACC
CGAGGCCGCGGCCTGCCCCCCTGGCCTCCTGAGAGCCCCAGGCTCCGGCTCCTCCTACCCCAGC
AGCCTGGCCAAGGCTGGGCCCGACAGGGCCTCGTACCACCTGGAATACAGCCCCCAGCGGGGTA
AGGCTGAGGCCAGCGGTGGCTTCTACGGCACAGGCAGCCAGCTGAGCCTGGAAAGATGCGCACT
TCACTTTGAAGACGCCAGGCCTCCTGGACTGGAGGAGCCAGGACGGGGCCCAGACACCTACTGT
AGCCCCAGTTCCCACAGCGCCTTGGAGGCATCCTATGCCTCCCTGATGGAGACTGAGCACCTGG
TACAGAATGTTTGTAAGTCCTACCGAGAGACGTGTCAGTTGCGGCTGGAGGACCTGCTACGGCA
GCGCCCTAACATCTTCTCCCGGGAGGAGGTGGCCAGCTACCAGAGGAAGTCCATGTGGGAGATG
TGGGAACGCTGTGCCCACCGCCTCACCGAGGCCATTCAGTACGTGGTGGAGTTCGCGAAGAGGC
TCTCAGGCTTTATGGAGCTCTGCCAGAATGACCAGATTGTGCTTCTCAAAGCAGGAGCAATGGA
AGTGGTTCTGGTCCGGATGTGCCGGGCTTACAATGCTGACAACCACACAGTCTTTTTCGAAGGC
AAATACGGTGGCATGGAGCTGTTCCGAGCCTTGGGCTGCAGCGAGCTCATCAGCTCCATCTTTG
ACTTCTCCCGCTCCCTGAGTTCCTTGCGCTTTTCTGAGGATGAGATTGCTCTCTACACGGCCCT
GGTCCTCATCAACGCCAACCGTCCGGGGCTCCAAGAGAAAAGGAAAGTAGAACAGCTACAGCAC
AACCTGGAGCAGGCTTTTCATCACCATCTCTACAGGACTCACCGCCAAGGCATCCTGGCAAAGC
TGCCGCCCAAGGGGAAGCTTCGGAGCCTGTGCAGCCAGCATGTGGAAAAGCTGCACACTTTCCA
ACATCTCCACCCCATCGTGGTCCAAGCCACTTTCCCTCCACTCTACAAGGAACTCTTCAGCACT
GAAATCGAGTCACCTGAAGGGCTGTCTGAGTGACCTGAAGAACGGACTCCTTTCCCTCCCCTTG
AGCCTACTGGCCCTCTTCCCTGGATCTCCTCCCACCTTCATATTTTTCTTACCTGTGCCCCGGG
AGGGTGGTCTCCGCCTATTCTCTAGGGATGAGCAATTGCTGAGACTGGCTTTCTGCCCACAGGC
GTGCCTGGCAGTGGGCCAAGAGCCAGAGGGTGGTGATGAAGGAACACCATCTCCAGCCTCAGCG
TTGTTGCATCTGCTCTCCCATGACCCTTCACCCCCAGCTTCTGAGAGGCCTGGGGTGGCACATA
AGGACCTCTAGGAGGACCATGGTGTCCTCAGGACACCAGGAGAATCCAGTCGACTCTGGGCTCA
GAAGCTAAGAATAGGACTTTAAAATACCTCATTGCATTTCCCTGTGGGCTTTGGCTGGGGATAT
GTGTCAAGCTCAGAGACTGGCAGCTGGAGCCCAGAAGGACCTGTATATAACATGAATCCAGATC
TTTA

hide sequence

RefSeq Acc Id:

XM_005630826 ⟹ XP_005630883

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	60,821,498 - 60,842,485 (-)	NCBI
Dog10K_Boxer_Tasha	17	60,263,366 - 60,285,188 (-)	NCBI

Sequence:

show sequence

CCTCCCTCCCCTGGGCCCTGCTCCCTGCCCTCCTGGGCAGCCAGGGCAGCAAGGACGGCACCCA
GGGAGCTGCCCCATGGACAGGGCCCCACAGAGACAGCACCGAGCCTCGCAGGAGCTGCTGGCTG
CCAAGAAGACCCACACCTCACAAATCGAAGTGATTCCTTGCAAAATCTGTGGAGACAAGTCATC
TGGGATCCACTACGGGGTGATCACCTGTGAGGGATGCAAGGGTTTCTTCCGCCGGAGCCAGCAG
TGTAACGTGGTCTACTCCTGCACCCGCCAGCAGAACTGCCCCATCGACCGCACCAGCCGAAACC
GATGTCAACACTGCCGCCTGCAGAAATGCCTGGCACTGGGCATGTCCCGAGATGCTGTCAAGTT
CGGCCGCATGTCCAAGAAGCAGAGGGACAGCCTGCACGCCGAGGTGCAGAAACAGCTGCAGCGG
CAGCAACAGCAGCAGCGAGGACAGGTGGCCAAGACCCCACCAGCGGGGGGCCAGGGAGCTGACC
CCCTCGCCTGCCCCATAGGGCTCCCAGATGGGCAGCTGCCCCTGGGCTCATCACCTGACCTACC
CGAGGCCGCGGCCTGCCCCCCTGGCCTCCTGAGAGCCCCAGGCTCCGGCTCCTCCTACCCCAGC
AGCCTGGCCAAGGCTGGGCCCGACAGGGCCTCGTACCACCTGGAATACAGCCCCCAGCGGGGTA
AGGCTGAGGCCAGCGGTGGCTTCTACGGCACAGGCAGCCAGCTGAGCCTGGAAAGATGCGCACT
TCACTTTGAAGACGCCAGGCCTCCTGGACTGGAGGAGCCAGGACGGGGCCCAGACACCTACTGT
AGCCCCAGTTCCCACAGCGCCTTGGAGGCATCCTATGCCTCCCTGATGGAGACTGAGCACCTGG
TACAGAATGTTTGTAAGTCCTACCGAGAGACGTGTCAGTTGCGGCTGGAGGACCTGCTACGGCA
GCGCCCTAACATCTTCTCCCGGGAGGAGGTGGCCAGCTACCAGAGGAAGTCCATGTGGGAGATG
TGGGAACGCTGTGCCCACCGCCTCACCGAGGCCATTCAGTACGTGGTGGAGTTCGCGAAGAGGC
TCTCAGGCTTTATGGAGCTCTGCCAGAATGACCAGATTGTGCTTCTCAAAGCAGGCTGCAGCGA
GCTCATCAGCTCCATCTTTGACTTCTCCCGCTCCCTGAGTTCCTTGCGCTTTTCTGAGGATGAG
ATTGCTCTCTACACGGCCCTGGTCCTCATCAACGCCAACCGTCCGGGGCTCCAAGAGAAAAGGA
AAGTAGAACAGCTACAGCACAACCTGGAGCAGGCTTTTCATCACCATCTCTACAGGACTCACCG
CCAAGGCATCCTGGCAAAGCTGCCGCCCAAGGGGAAGCTTCGGAGCCTGTGCAGCCAGCATGTG
GAAAAGCTGCACACTTTCCAACATCTCCACCCCATCGTGGTCCAAGCCACTTTCCCTCCACTCT
ACAAGGAACTCTTCAGCACTGAAATCGAGTCACCTGAAGGGCTGTCTGAGTGACCTGAAGAACG
GACTCCTTTCCCTCCCCTTGAGCCTACTGGCCCTCTTCCCTGGATCTCCTCCCACCTTCATATT
TTTCTTACCTGTGCCCCGGGAGGGTGGTCTCCGCCTATTCTCTAGGGATGAGCAATTGCTGAGA
CTGGCTTTCTGCCCACAGGCGTGCCTGGCAGTGGGCCAAGAGCCAGAGGGTGGTGATGAAGGAA
CACCATCTCCAGCCTCAGCGTTGTTGCATCTGCTCTCCCATGACCCTTCACCCCCAGCTTCTGA
GAGGCCTGGGGTGGCACATAAGGACCTCTAGGAGGACCATGGTGTCCTCAGGACACCAGGAGAA
TCCAGTCGACTCTGGGCTCAGAAGCTAAGAATAGGACTTTAAAATACCTCATTGCATTTCCCTG
TGGGCTTTGGCTGGGGATATGTGTCAAGCTCAGAGACTGGCAGCTGGAGCCCAGAAGGACCTGT
ATATAACATGAATCCAGATCTTTA

hide sequence

RefSeq Acc Id:

XM_038423216 ⟹ XP_038279144

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	61,838,557 - 61,860,379 (-)	NCBI

RefSeq Acc Id:

XM_038423217 ⟹ XP_038279145

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	61,838,557 - 61,860,379 (-)	NCBI

RefSeq Acc Id:

XM_038423218 ⟹ XP_038279146

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	17	61,838,557 - 61,852,021 (-)	NCBI

RefSeq Acc Id:

XM_038453350 ⟹ XP_038309278

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	17	60,263,366 - 60,276,828 (-)	NCBI

RefSeq Acc Id:

XM_038499702 ⟹ XP_038355630

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	17	60,665,332 - 60,687,158 (-)	NCBI

RefSeq Acc Id:

XM_038562271 ⟹ XP_038418199

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	61,480,593 - 61,502,436 (-)	NCBI

RefSeq Acc Id:

XM_038562272 ⟹ XP_038418200

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	61,480,593 - 61,502,436 (-)	NCBI

RefSeq Acc Id:

XM_038562273 ⟹ XP_038418201

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	17	61,480,593 - 61,494,076 (-)	NCBI

RefSeq Acc Id:

XM_038626366 ⟹ XP_038482294

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	60,751,477 - 60,773,308 (-)	NCBI

RefSeq Acc Id:

XM_038626367 ⟹ XP_038482295

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	60,751,477 - 60,773,308 (-)	NCBI

RefSeq Acc Id:

XM_038626368 ⟹ XP_038482296

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	17	60,751,477 - 60,764,949 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005630882	(Get FASTA)	NCBI Sequence Viewer
	XP_005630883	(Get FASTA)	NCBI Sequence Viewer
	XP_038279144	(Get FASTA)	NCBI Sequence Viewer
	XP_038279145	(Get FASTA)	NCBI Sequence Viewer
	XP_038279146	(Get FASTA)	NCBI Sequence Viewer
	XP_038309278	(Get FASTA)	NCBI Sequence Viewer
	XP_038355630	(Get FASTA)	NCBI Sequence Viewer
	XP_038418199	(Get FASTA)	NCBI Sequence Viewer
	XP_038418200	(Get FASTA)	NCBI Sequence Viewer
	XP_038418201	(Get FASTA)	NCBI Sequence Viewer
	XP_038482294	(Get FASTA)	NCBI Sequence Viewer
	XP_038482295	(Get FASTA)	NCBI Sequence Viewer
	XP_038482296	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000019006.4
	ENSCAFP00000047912.1
	ENSCAFP00030017289.1
	ENSCAFP00030017351.1
	ENSCAFP00040024860.1
	ENSCAFP00845034781
	ENSCAFP00845034781.1
	ENSCAFP00845034868
	ENSCAFP00845034868.1

RefSeq Acc Id:	XP_005630883 ⟸ XM_005630826
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SSJ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDRAPQRQHRASQELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVV YSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQRQQQQ QRGQVAKTPPAGGQGADPLACPIGLPDGQLPLGSSPDLPEAAACPPGLLRAPGSGSSYPSSLAK AGPDRASYHLEYSPQRGKAEASGGFYGTGSQLSLERCALHFEDARPPGLEEPGRGPDTYCSPSS HSALEASYASLMETEHLVQNVCKSYRETCQLRLEDLLRQRPNIFSREEVASYQRKSMWEMWERC AHRLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGCSELISSIFDFSRSLSSLRFSEDEIALY TALVLINANRPGLQEKRKVEQLQHNLEQAFHHHLYRTHRQGILAKLPPKGKLRSLCSQHVEKLH TFQHLHPIVVQATFPPLYKELFSTEIESPEGLSE hide sequence

RefSeq Acc Id:	XP_005630882 ⟸ XM_005630825
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0MZK9 (UniProtKB/TrEMBL), A0A8I3PTL7 (UniProtKB/TrEMBL), A0A8C0SSJ2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDRAPQRQHRASQELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVV YSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQRQQQQ QRGQVAKTPPAGGQGADPLACPIGLPDGQLPLGSSPDLPEAAACPPGLLRAPGSGSSYPSSLAK AGPDRASYHLEYSPQRGKAEASGGFYGTGSQLSLERCALHFEDARPPGLEEPGRGPDTYCSPSS HSALEASYASLMETEHLVQNVCKSYRETCQLRLEDLLRQRPNIFSREEVASYQRKSMWEMWERC AHRLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNHTVFFEGKYGG MELFRALGCSELISSIFDFSRSLSSLRFSEDEIALYTALVLINANRPGLQEKRKVEQLQHNLEQ AFHHHLYRTHRQGILAKLPPKGKLRSLCSQHVEKLHTFQHLHPIVVQATFPPLYKELFSTEIES PEGLSE hide sequence

RefSeq Acc Id:

ENSCAFP00000019006 ⟸ ENSCAFT00000020479

RefSeq Acc Id:

ENSCAFP00000047912 ⟸ ENSCAFT00000079712

RefSeq Acc Id:	XP_038355630 ⟸ XM_038499702
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038482295 ⟸ XM_038626367
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038482294 ⟸ XM_038626366
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038482296 ⟸ XM_038626368
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038279145 ⟸ XM_038423217
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SSJ2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038279144 ⟸ XM_038423216
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0MZK9 (UniProtKB/TrEMBL), A0A8I3PTL7 (UniProtKB/TrEMBL), A0A8C0SSJ2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038279146 ⟸ XM_038423218
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K974 (UniProtKB/TrEMBL), A0A8C0MV51 (UniProtKB/TrEMBL), A0A8I3PP78 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038309278 ⟸ XM_038453350
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K974 (UniProtKB/TrEMBL), A0A8C0MV51 (UniProtKB/TrEMBL), A0A8I3PP78 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418200 ⟸ XM_038562272
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0SSJ2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418199 ⟸ XM_038562271
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0MZK9 (UniProtKB/TrEMBL), A0A8C0SSJ2 (UniProtKB/TrEMBL), A0A8I3PTL7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038418201 ⟸ XM_038562273
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0K974 (UniProtKB/TrEMBL), A0A8C0MV51 (UniProtKB/TrEMBL), A0A8I3PP78 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845034868 ⟸ ENSCAFT00845044500

RefSeq Acc Id:

ENSCAFP00845034781 ⟸ ENSCAFT00845044385

Protein Domains

NR LBD Nuclear receptor

Promoters

RGD ID:

13686410

Promoter ID:

EPDNEW_C4476

Type:

multiple initiation site

Name:

RORC_1

Description:

RAR related orphan receptor C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	17	60,842,443 - 60,842,503	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000012884	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030010688	UniProtKB/TrEMBL
	ENSCAFG00040015522	UniProtKB/TrEMBL
	ENSCAFG00845025144	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000020479.6	UniProtKB/TrEMBL
	ENSCAFT00000079712.2	UniProtKB/TrEMBL
	ENSCAFT00030019824.1	UniProtKB/TrEMBL
	ENSCAFT00030019910.1	UniProtKB/TrEMBL
	ENSCAFT00040028617.1	UniProtKB/TrEMBL
	ENSCAFT00845044385	ENTREZGENE
	ENSCAFT00845044385.1	UniProtKB/TrEMBL
	ENSCAFT00845044500	ENTREZGENE
	ENSCAFT00845044500.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.565.10	UniProtKB/TrEMBL
	3.30.50.10	UniProtKB/TrEMBL
InterPro	NHR-like_dom_sf	UniProtKB/TrEMBL
	NR_DBD_ROR	UniProtKB/TrEMBL
	Nucl_hrmn_rcpt_lig-bd	UniProtKB/TrEMBL
	Nuclear_hrmn_rcpt	UniProtKB/TrEMBL
	ROR_rcpt	UniProtKB/TrEMBL
	Znf_hrmn_rcpt	UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/TrEMBL
KEGG Report	cfa:483205	UniProtKB/TrEMBL
NCBI Gene	RORC	ENTREZGENE
PANTHER	NUCLEAR HORMONE RECEPTOR HR3-RELATED	UniProtKB/TrEMBL
	NUCLEAR RECEPTOR ROR-GAMMA	UniProtKB/TrEMBL
Pfam	Hormone_recep	UniProtKB/TrEMBL
	zf-C4	UniProtKB/TrEMBL
PRINTS	RORNUCRECPTR	UniProtKB/TrEMBL
	STRDHORMONER	UniProtKB/TrEMBL
	STROIDFINGER	UniProtKB/TrEMBL
PROSITE	NR_LBD	UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_1	UniProtKB/TrEMBL
	NUCLEAR_REC_DBD_2	UniProtKB/TrEMBL
SMART	HOLI	UniProtKB/TrEMBL
	ZnF_C4	UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/TrEMBL
	SSF48508	UniProtKB/TrEMBL
UniProt	A0A8C0K974	ENTREZGENE
	A0A8C0MV51	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0MZK9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0SSJ2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PP78	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I3PTL7	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:45697	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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