GATA4 (GATA binding protein 4) - Rat Genome Database

Name: GATA4
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: GATA4 (GATA binding protein 4) Canis lupus familiaris

Analyze

Symbol:

GATA4

Name:

GATA binding protein 4

RGD ID:

12380597

Description:

ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); co-SMAD binding (ortholog); INVOLVED IN aortic valve morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrial septum primum morphogenesis (ortholog); ASSOCIATED WITH 46,XY sex reversal 3 (ortholog); alcohol use disorder (ortholog); Animal Disease Models (ortholog); FOUND IN chromatin (ortholog); nuclear body (ortholog); nucleus (ortholog); INTERACTS WITH enalapril; metoprolol; ranolazine

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

GATA-binding factor 4; transcription factor GATA-4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GATA4 (GATA binding protein 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Treefam
Mus musculus (house mouse):	Gata4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Gata4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gata4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GATA4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gata4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GATA4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GATA4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gata4 (GATA binding protein 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	26,126,172 - 26,211,474 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	26,127,853 - 26,182,989 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	26,784,428 - 26,835,191 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	26,280,507 - 26,366,154 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	26,280,510 - 26,337,654 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	26,235,249 - 26,286,037 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	26,131,847 - 26,182,607 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	26,283,313 - 26,334,650 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

46,XY sex reversal 3 (ISO)

alcohol use disorder (ISO)

Animal Disease Models (ISO)

atrial fibrillation (ISO)

atrial heart septal defect (ISO)

atrial heart septal defect 2 (ISO)

atrioventricular septal defect (ISO)

Atrioventricular Septal Defect 4 (ISO)

Cardiomegaly (ISO)

Colorectal Neoplasms (ISO)

congenital diaphragmatic hernia (ISO)

congenital heart disease (ISO)

dextro-looped transposition of the great arteries (ISO)

Diaphragmatic Hernia (ISO)

dilated cardiomyopathy (ISO)

Experimental Diabetes Mellitus (ISO)

genetic disease (ISO)

Hemorrhage (ISO)

intellectual disability (ISO)

maturity-onset diabetes of the young type 5 (ISO)

microcephaly (ISO)

myocardial infarction (ISO)

Neurodevelopmental Disorders (ISO)

Pulmonary Atresia (ISO)

pulmonary hypertension (ISO)

pulmonary valve stenosis (ISO)

Testicular Anomalies with or without Congenital Heart Disease (ISO)

tetralogy of Fallot (ISO)

thoracic aortic aneurysm (ISO)

tricuspid valve insufficiency (ISO)

type 1 diabetes mellitus (ISO)

Ventricular Remodeling (ISO)

ventricular septal defect (ISO)

Ventricular Septal Defect 1 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

enalapril (EXP)

metoprolol (EXP)

ranolazine (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aortic valve morphogenesis (ISO)

atrial septum morphogenesis (ISO)

atrial septum primum morphogenesis (ISO)

atrial septum secundum morphogenesis (ISO)

atrioventricular canal development (ISO)

atrioventricular valve formation (ISO)

atrioventricular valve morphogenesis (ISO)

cardiac muscle cell differentiation (ISO)

cardiac muscle cell proliferation (ISO)

cardiac muscle hypertrophy in response to stress (ISO)

cardiac muscle tissue development (ISO)

cardiac muscle tissue regeneration (ISO)

cardiac right ventricle morphogenesis (ISO)

cardiac septum development (ISO)

cell fate commitment (IBA,IEA)

cell growth involved in cardiac muscle cell development (ISO)

cell-cell signaling (ISO)

cellular response to follicle-stimulating hormone stimulus (ISO)

cellular response to glucose stimulus (ISO)

cellular response to gonadotropin stimulus (ISO)

embryonic digestive tract morphogenesis (ISO)

embryonic foregut morphogenesis (ISO)

embryonic heart tube anterior/posterior pattern specification (ISO)

embryonic heart tube development (ISO)

embryonic morphogenesis (ISO)

endocardial cushion development (ISO)

endoderm formation (ISO)

epithelial cell fate commitment (ISO)

gastrulation with mouth forming second (ISO)

heart development (IEA,ISO)

heart looping (ISO)

heart morphogenesis (ISO)

in utero embryonic development (ISO)

intestinal epithelial cell differentiation (ISO)

lung lobe formation (ISO)

male gonad development (ISO)

negative regulation of apoptotic process (ISO)

negative regulation of apoptotic signaling pathway (ISO)

negative regulation of autophagy (ISO)

negative regulation of cardiac muscle cell apoptotic process (ISO)

negative regulation of connective tissue replacement (ISO)

negative regulation of gene expression (ISO)

negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (ISO)

negative regulation of transcription by RNA polymerase II (IBA,IEA)

positive regulation of angiogenesis (ISO)

positive regulation of BMP signaling pathway (ISO)

positive regulation of cardiac muscle cell proliferation (ISO)

positive regulation of cell cycle (ISO)

positive regulation of DNA-templated transcription (IEA,ISO,ISS)

positive regulation of gene expression (ISO)

positive regulation of miRNA transcription (ISO)

positive regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

positive regulation of vascular endothelial growth factor production (ISO)

regulation of cardiac muscle cell contraction (ISO)

regulation of cardiac muscle cell proliferation (ISO)

regulation of DNA-templated transcription (ISO)

regulation of gene expression (ISO)

regulation of transcription by RNA polymerase II (IEA,ISO)

response to estrogen (ISO)

response to mechanical stimulus (ISO)

response to retinoic acid (ISO)

response to vitamin A (ISO)

response to xenobiotic stimulus (ISO)

seminiferous tubule development (ISO)

Sertoli cell differentiation (ISO)

signal transduction involved in regulation of gene expression (ISO)

spermatogenesis (ISO)

tissue development (IEA)

transdifferentiation (ISO)

tube morphogenesis (ISO)

ventricular cardiac muscle tissue development (ISO)

ventricular septum development (ISO)

wound healing (ISO)

Cellular Component

chromatin (ISO)

nuclear body (ISO)

nucleus (IBA,IEA,ISS)

RNA polymerase II transcription regulator complex (ISO)

Molecular Function

chromatin binding (ISO)

cis-regulatory region sequence-specific DNA binding (ISO)

co-SMAD binding (ISO)

DNA binding (IEA,ISS)

DNA-binding transcription activator activity (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA,IEA,ISO)

DNA-binding transcription factor binding (ISO)

metal ion binding (IEA)

NFAT protein binding (ISO)

protein binding (ISO)

protein kinase binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IEA)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II-specific DNA-binding transcription factor binding (ISO)

sequence-specific DNA binding (IEA,ISO)

sequence-specific double-stranded DNA binding (ISO)

transcription cis-regulatory region binding (IEA)

transcription coactivator binding (ISO)

transcription factor binding (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:18305343	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

GATA4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	26,126,172 - 26,211,474 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	26,127,853 - 26,182,989 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	26,784,428 - 26,835,191 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	26,280,507 - 26,366,154 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	26,280,510 - 26,337,654 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	26,235,249 - 26,286,037 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	26,131,847 - 26,182,607 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	26,283,313 - 26,334,650 (-)	NCBI		UU_Cfam_GSD_1.0

GATA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	11,676,935 - 11,760,002 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	11,676,959 - 11,760,002 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	11,534,444 - 11,617,511 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	11,599,162 - 11,654,918 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	11,599,161 - 11,654,918	NCBI
Celera	8	10,690,994 - 10,746,848 (+)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	10,492,698 - 10,548,485 (+)	NCBI		HuRef
CHM1_1	8	11,627,233 - 11,683,005 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	7,980,285 - 8,063,322 (-)	NCBI		T2T-CHM13v2.0

Gata4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	63,436,363 - 63,509,161 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	63,436,371 - 63,509,141 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	63,198,914 - 63,271,712 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	63,198,922 - 63,271,692 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	63,817,752 - 63,864,097 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	62,153,032 - 62,199,370 (-)	NCBI		MGSCv36	mm8
Celera	14	60,962,648 - 61,008,982 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	33.24	NCBI

Gata4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	41,635,572 - 41,707,252 (-)	NCBI		GRCr8
mRatBN7.2	15	37,459,601 - 37,531,291 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	37,459,601 - 37,505,636 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	39,312,354 - 39,358,379 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	40,463,161 - 40,509,184 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	38,920,232 - 38,966,261 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	46,386,703 - 46,458,679 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	46,386,712 - 46,432,965 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	50,151,497 - 50,197,708 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	42,472,793 - 42,519,569 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	42,488,492 - 42,535,269 (-)	NCBI
Celera	15	37,143,928 - 37,189,874 (-)	NCBI		Celera
RH 3.4 Map	15	261.71	RGD
Cytogenetic Map	15	p12	NCBI

Gata4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	52,987,644 - 53,029,267 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	52,958,318 - 53,029,267 (+)	NCBI	ChiLan1.0	ChiLan1.0

GATA4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	28,171,698 - 28,227,399 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	4,197,937 - 4,253,651 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	7,442,921 - 7,526,731 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

Gata4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	5,165,238 - 5,177,602 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936675	3,408,549 - 3,420,828 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GATA4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	14,884,662 - 14,939,941 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	14,858,470 - 14,938,156 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	16,046,527 - 16,126,816 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GATA4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	7,348,145 - 7,432,574 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	7,349,660 - 7,400,562 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	35,034,077 - 35,087,089 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gata4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	25,278,874 - 25,319,318 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	25,278,878 - 25,319,317 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in GATA4
1059 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium		5	4	4		4
Low			2	2		2				8
Below cutoff	5		16		6		6	2	12		10	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001048112	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_014107460	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409565	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022409567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434566	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434567	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ666280	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000048684 ⟹ ENSCAFP00000038219

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	25	26,127,853 - 26,182,989 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845034032 ⟹ ENSCAFP00845026636

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	25	26,280,510 - 26,337,654 (-)	Ensembl

RefSeq Acc Id:

NM_001048112 ⟹ NP_001041577

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	25	26,127,853 - 26,178,331 (-)	NCBI
Dog10K_Boxer_Tasha	25	26,784,428 - 26,835,191 (-)	NCBI
ROS_Cfam_1.0	25	26,282,188 - 26,333,082 (-)	NCBI
UMICH_Zoey_3.1	25	26,235,249 - 26,286,037 (-)	NCBI
UNSW_CanFamBas_1.0	25	26,131,847 - 26,182,607 (-)	NCBI
UU_Cfam_GSD_1.0	25	26,283,313 - 26,334,650 (-)	NCBI

Sequence:

show sequence

ATGTACCAGAGCCTGGCCATGGCCGCCAACCACGGCCCCCCTCCCGGCGCCTACGAGGCGGGCG
GCCCCGGCGCCTTCATGCACGGCGCGGGCGCCGCGTCCTCGCCGGTCTACGTGCCCACGCCGCG
GGTGCCCTCGTCCGTGCTGGGCCTGTCCTACCTGCAGGGCGGAGGCGGGGCCGCGGCGTCCGGG
GCCTCCTCGGGCGGCGGCTCCGGCGGGGCCCCGTCGGCGGCCGGGCCCGGAGCCCAGCAGGGCA
GCCCGGGCTGGAGCCAGGCGGGCGCCGACGGAGCCGCCTACACGCCCCCGCCCGTGTCGCCGCG
CTTCTCCTTCCCGGGGACCACCGGGTCCCTGGCCGCCGCCGCCGCCGCCGCCGCCGCCCGGGAG
GCCGCGGCCTACGGCGGGGGCGGCGGGGCGGCGGGCGCGGGCCTGGCCGGCCGCGAGCAGTACG
GGCGCGCGGGCTTCGCGGGCTCCTACTCCAGCCCCTACCCCGCCTACATGGCCGACGTGGGCGC
GTCCTGGGCCGCGGCCGCCGCCGCCTCCGCCGGCCCCTTCGACAGCCCGGTGCTGCACAGCCTG
CCCGGCAGGGCCAACCCCGCCGCCCGACACCCCAACCTCGATATGTTTGATGACTTCTCAGAAG
GTAGAGAATGTGTCAACTGTGGGGCCATGTCCACCCCGCTCTGGAGGCGTGATGGGACGGGGCA
CTACCTGTGCAATGCCTGCGGCCTCTACCACAAGATGAATGGCATCAACCGGCCCCTCATTAAG
CCTCAGCGCCGGCTGTCCGCCTCCCGCCGAGTGGGCCTGTCCTGTGCCAACTGCCAGACCACCA
CCACCACTCTGTGGCGCCGCAATGCTGAGGGTGAGCCAGTGTGCAATGCCTGCGGCCTCTACAT
GAAGCTCCATGGTGTTCCAAGGCCTCTTGCAATGCGGAAAGAGGGGATTCAAACCAGAAAACGG
AAGCCCAAGAACCTTAATAAATCTAAGACACCAGCAGGTCCCTCAGGCGGTGAGAGCCTTCCTC
CTGCCAGCAGTGCTTCCAGCAACTCCAGCAATGTGGCCACCAGCAGCAGTGAAGAGATGCGCCC
CATCAAGACAGAGCCCGGGCTATCATCCCACTATGGGCACAGCAGCTCCATGTCCCAGACATTC
TCAGTCAGTGCGATGTCTGGCCACGGGCCCTCCATCCACCCAGTCCTCTCGGCCCTGAAGCTCT
CCCCACAAGGCTACACATCTTCTGTCAGCCAGTCGCCACAGGCCAGCTCCAAGCAGGACCCTTG
GAACAGCCTGGCCTTGGCTGACAGTCACGGGGACATAATCACTGCATAA

hide sequence

RefSeq Acc Id:

XM_038434566 ⟹ XP_038290494

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	25	26,280,507 - 26,337,389 (-)	NCBI

RefSeq Acc Id:

XM_038434567 ⟹ XP_038290495

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	25	26,280,507 - 26,366,154 (-)	NCBI

RefSeq Acc Id:

XM_038434568 ⟹ XP_038290496

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	25	26,280,507 - 26,337,388 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001041577	(Get FASTA)	NCBI Sequence Viewer
	XP_038290494	(Get FASTA)	NCBI Sequence Viewer
	XP_038290495	(Get FASTA)	NCBI Sequence Viewer
	XP_038290496	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABG75570	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000038219.1
	ENSCAFP00030028589.1
	ENSCAFP00030028637.1
	ENSCAFP00040035895.1
	ENSCAFP00805021524
	ENSCAFP00845026636
	ENSCAFP00845026636.1
GenBank Protein	Q0Q0E4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001041577 ⟸ NM_001048112

- UniProtKB:

Q0Q0E4 (UniProtKB/Swiss-Prot), A0A8C0TK74 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MYQSLAMAANHGPPPGAYEAGGPGAFMHGAGAASSPVYVPTPRVPSSVLGLSYLQGGGGAAASG
ASSGGGSGGAPSAAGPGAQQGSPGWSQAGADGAAYTPPPVSPRFSFPGTTGSLAAAAAAAAARE
AAAYGGGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAASAGPFDSPVLHSL
PGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNACGLYHKMNGINRPLIK
PQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMKLHGVPRPLAMRKEGIQTRKR
KPKNLNKSKTPAGPSGGESLPPASSASSNSSNVATSSSEEMRPIKTEPGLSSHYGHSSSMSQTF
SVSAMSGHGPSIHPVLSALKLSPQGYTSSVSQSPQASSKQDPWNSLALADSHGDIITA

hide sequence

RefSeq Acc Id:

ENSCAFP00000038219 ⟸ ENSCAFT00000048684

RefSeq Acc Id:	XP_038290495 ⟸ XM_038434567
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KFU3 (UniProtKB/TrEMBL), A0A8C0TK74 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038290494 ⟸ XM_038434566
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0KFU3 (UniProtKB/TrEMBL), A0A8C0TK74 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038290496 ⟸ XM_038434568
- Peptide Label:	isoform X2
- UniProtKB:	Q0Q0E4 (UniProtKB/Swiss-Prot), A0A8C0TK74 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845026636 ⟸ ENSCAFT00845034032

Protein Domains

GATA-type

Promoters

RGD ID:

13687762

Promoter ID:

EPDNEW_C5831

Type:

single initiation site

Name:

GATA4_2

Description:

Transcription factor GATA-4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_C5832

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	25	26,178,536 - 26,178,596	EPDNEW

RGD ID:

13687763

Promoter ID:

EPDNEW_C5832

Type:

multiple initiation site

Name:

GATA4_1

Description:

Transcription factor GATA-4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_C5831

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	25	26,182,667 - 26,182,727	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000029087	Ensembl, UniProtKB/Swiss-Prot
	ENSCAFG00030017775	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSCAFG00040022159	UniProtKB/TrEMBL
	ENSCAFG00805015092	UniProtKB/Swiss-Prot
	ENSCAFG00845019258	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSCAFT00000048684.3	UniProtKB/Swiss-Prot
	ENSCAFT00030032771.1	UniProtKB/Swiss-Prot
	ENSCAFT00030032829.1	UniProtKB/TrEMBL
	ENSCAFT00040041168.1	UniProtKB/TrEMBL
	ENSCAFT00805027409	UniProtKB/Swiss-Prot
	ENSCAFT00845034032	ENTREZGENE
	ENSCAFT00845034032.1	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.50.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GATA_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TF_GATA_4/5/6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transcription_factor_GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_NHR/GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:486079	UniProtKB/Swiss-Prot
NCBI Gene	GATA4	ENTREZGENE
PANTHER	PTHR10071	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR GATA-4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GATA-N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF	TF_GATA_4/5/6	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GATAZNFINGER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	GATA_ZN_FINGER_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GATA_ZN_FINGER_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	ZnF_GATA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Glucocorticoid receptor-like (DNA-binding domain)	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8C0KFU3	ENTREZGENE
	A0A8C0P2A3_CANLF	UniProtKB/TrEMBL
	A0A8C0TK74	ENTREZGENE, UniProtKB/TrEMBL
	GATA4_CANLF	UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID	VGNC:54949	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM