P2RX6 (purinergic receptor P2X 6)

Gene: P2RX6 (purinergic receptor P2X 6) Canis lupus familiaris

Analyze

Symbol:

P2RX6

Name:

purinergic receptor P2X 6

RGD ID:

12306655

Description:

ENCODES a protein that exhibits extracellularly ATP-gated monoatomic cation channel activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN calcium ion transmembrane transport (inferred); excitatory postsynaptic potential (inferred); monoatomic cation transmembrane transport (inferred); ASSOCIATED WITH autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); chromosome 22q11.2 microduplication syndrome (ortholog); FOUND IN dendritic spine (ortholog); glutamatergic synapse (ortholog); neuronal cell body (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

P2RXL1; P2X purinoceptor 6; purinergic receptor P2X, ligand-gated ion channel, 6; purinergic receptor P2X-like 1, orphan receptor

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	30,456,231 - 30,467,674 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	30,457,014 - 30,466,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	30,417,349 - 30,428,575 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	31,867,789 - 31,879,013 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	31,869,314 - 31,879,069 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	29,913,614 - 29,924,837 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	29,537,801 - 29,549,022 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	30,626,779 - 30,638,005 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

chromosome 22q11.2 deletion syndrome, distal (ISO)

chromosome 22q11.2 microduplication syndrome (ISO)

DiGeorge syndrome (ISO)

epilepsy (ISO)

genetic disease (ISO)

intellectual disability (ISO)

megacolon (ISO)

Neurodevelopmental Disorders (ISO)

primary immunodeficiency disease (ISO)

schizophrenia (ISO)

velocardiofacial syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

calcium ion transmembrane transport (IEA)

excitatory postsynaptic potential (IEA)

monoatomic cation transmembrane transport (IEA)

monoatomic ion transmembrane transport (IEA)

purinergic nucleotide receptor signaling pathway (IEA)

response to ATP (IEA)

signal transduction (IEA)

Cellular Component

cell junction (IEA)

cytoplasm (IEA)

dendritic spine (ISO)

glutamatergic synapse (ISO)

membrane (IEA)

neuronal cell body (ISO)

parallel fiber to Purkinje cell synapse (ISO)

plasma membrane (IEA)

postsynapse (IEA)

postsynaptic specialization membrane (ISO)

receptor complex (IEA)

Molecular Function

ATP binding (IEA)

channel activity (IEA)

extracellularly ATP-gated monoatomic cation channel activity (IEA,ISO)

protein binding (ISO)

protein-containing complex binding (ISO)

purinergic nucleotide receptor activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

P2RX6
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	30,456,231 - 30,467,674 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	30,457,014 - 30,466,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	30,417,349 - 30,428,575 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	31,867,789 - 31,879,013 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	31,869,314 - 31,879,069 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	29,913,614 - 29,924,837 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	29,537,801 - 29,549,022 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	30,626,779 - 30,638,005 (-)	NCBI		UU_Cfam_GSD_1.0

P2RX6
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	21,009,799 - 21,028,008 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	21,009,808 - 21,028,013 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	21,369,454 - 21,382,297 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	19,699,464 - 19,712,302 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	19,694,002 - 19,707,673	NCBI
Celera	22	4,860,745 - 4,873,604 (+)	NCBI		Celera
Cytogenetic Map	22	q11.21	NCBI
HuRef	22	4,637,727 - 4,650,586 (+)	NCBI		HuRef
CHM1_1	22	21,369,657 - 21,382,503 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	21,423,939 - 21,436,767 (+)	NCBI		T2T-CHM13v2.0

P2rx6
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	17,379,749 - 17,389,879 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	17,379,749 - 17,395,664 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	17,561,867 - 17,572,015 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	17,561,885 - 17,577,800 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	17,561,978 - 17,572,105 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	17,475,563 - 17,484,828 (+)	NCBI		MGSCv36	mm8
Celera	16	18,135,205 - 18,145,330 (+)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	10.88	NCBI

P2rx6
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	96,944,167 - 96,956,424 (-)	NCBI		GRCr8
mRatBN7.2	11	83,439,922 - 83,450,449 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	83,439,924 - 83,450,481 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	92,167,552 - 92,177,610 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	84,828,716 - 84,838,772 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	83,882,324 - 83,892,380 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	87,434,929 - 87,445,221 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	87,435,185 - 87,445,219 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	90,485,985 - 90,496,515 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	85,431,257 - 85,441,293 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	85,471,855 - 85,481,771 (-)	NCBI
Celera	11	82,208,493 - 82,218,517 (-)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

P2rx6
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	19,264,790 - 19,271,537 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	19,263,544 - 19,272,231 (-)	NCBI	ChiLan1.0	ChiLan1.0

P2RX6
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	30,721,153 - 30,735,310 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	33,270,081 - 33,284,233 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	3,239,019 - 3,251,966 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	19,728,644 - 19,741,078 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	19,728,644 - 19,741,078 (+)	Ensembl	panpan1.1		panPan2

P2rx6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	140,186,450 - 140,193,553 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936619	2,560,759 - 2,566,355 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936619	2,560,685 - 2,567,612 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

P2RX6
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	50,622,938 - 50,633,535 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	50,595,876 - 50,633,536 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	54,043,227 - 54,082,269 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

P2RX6
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	4,958,713 - 4,969,443 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	4,958,671 - 4,969,724 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666085	2,001,874 - 2,015,701 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

P2rx6
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624945	648,499 - 656,075 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624945	646,361 - 687,901 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in P2RX6
143 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium						1
Low		5	5			5	11	8	4
Below cutoff	4		11	5	5		1		6	5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005636614	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022410552	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038437592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038512455	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038575955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038640165	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000286	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000026	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000023919 ⟹ ENSCAFP00000022204

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	30,457,675 - 30,465,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000045106 ⟹ ENSCAFP00000042799

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	30,457,131 - 30,466,152 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000071547 ⟹ ENSCAFP00000044330

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	30,457,084 - 30,465,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00000078857 ⟹ ENSCAFP00000047916

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	26	30,457,014 - 30,465,964 (+)	Ensembl

RefSeq Acc Id:

ENSCAFT00845041196 ⟹ ENSCAFP00845032288

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	26	31,869,314 - 31,879,069 (-)	Ensembl

RefSeq Acc Id:

XM_005636614 ⟹ XP_005636671

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	26	30,456,444 - 30,467,674 (+)	NCBI
Dog10K_Boxer_Tasha	26	30,417,349 - 30,428,575 (-)	NCBI

Sequence:

show sequence

GTGCGCGCGCCGGGGTTCGAGCAGAGCATCGCCCCCACACCTTCCGCCGACTGGGGAACGTGGC
TGACTCCGCAGCCTGTGCTTTTGTCCCTCCGCTTCCCCGGCACGCGGCGCCAGAGAAGCTGGGG
AACCTTGCAATGCCCGGTCACCCTCCTCTGTGGAGCCAGAGTCAGGCTCTCACCCTGTGGCTGC
TAGTTCTCATGCTCTAGCGTCGCACATGCTGCTTCAGCCACCAGGAACCTTCTTCCTCTCAACT
TTGCTTGTTGAGCTTAAGAATCTGCAAGTGTCAGCTCAGAGGTCATTTCTTCCTGAAGCTTTCT
TTCCTTGACCTCTCCTCTGGGCTCCTGCAGCCCCCAAGCTGCCCTCTCACAGTACCTGTGACAC
TTGACTTCTCCTCCTCCTCTCCTCCCCCAGGGAAGTGAAGCCAGAGGGCAGGGCGCAGGGGCTG
CTCCTCTCTGCCTGGCCCTGGGCCCCCTCAGAGGGAGAGGGTGGGAGGCTCAGGGCAGCTCCTT
GCTGGGGCTGAACCTGGGGCTGGGGCTGGTGGTGGAGGCTGGATCCTGTCCCCAGTGGAAGTGT
CCCTTTAATAGCTTGCTGGCCTGGTCCGGTTTGGGCGCCTGCTTTACCTCCTATTCAGCTGTGG
CTGCAGCTGCTGTGCTGACTCATGCGCCCCAGCAGCCGGCAGGAACTGCAAGCATGGGCTTCCC
AGGGGTCTTGGCAGGCTGGGGGCTTCTGGATTACAAAACCGAGAAGTATGTGATAACCAGGAAC
TGGCGGGTGGGCGCCCTGCAGAGGCTACTGCAGCTCGGGGTCATGACCTACGTGGTGGGGTGGG
CTCTCCTCGCCAAGAAAGGATACCAGGAGCGAGACCTGGACCCCCAGATTTCTGTCATCACCAA
ACTCAAAGGGGTTTCTGTGACCCAGATCAAGGAGCTGGGTAACCGGCTATGGGACGTAGCAGAT
TTCGTGAAGCCACCACAGGGAGAGAACACGTTCTTCTTGGTGACCAATTTTCTTGTGACACCAG
AACAAGTTCAGGACAAATGCCCAGAGCACCCCTCCATTCCGCTGGCTAATTGCTGGGCCGACGA
GGACTGTCCTGAAGGGGAGACGGGGACGCACAGCCACGGCATAAAAACAGGCCAGTGTGTGGAA
TTCAACGGTACCCACAGGACCTGTGAGATCCAGGGCTGGTGCCCCGTGGAGAGCGGCACTGTGC
CTGTGAAGCCACTACTGGTCCAGGCAGAGAACTTCACCCTGTTTGTCAAGAACACAGTCACCTT
CAACAAGTTCAATTTTTCCAAGTCCAATGCCTTGGACACCTGGGATGCCACTTACTTCAAGCGC
TGCCGCTACGACTCACACTACAGCCCCTACTGCCCTGTGTTCCGCATTGGGGACCTCGTGGCTG
CAGCTGGAGGGGTCTTTGAGGACCTGGCGTTGCTGGGAGGTGCTGTGGGAGTCCGAGTCCACTG
GGATTGTGACCTGGATGCTGGGGCTTCCGACTGCCGGCCCCATTACTCCTTCCAGCTGCAGGAG
AGGAGCTACAATTTCAGGACAGCCTCTCACTGGTGGAAGGCCTCAGGTGTGGAGGCCCGGAGTC
TGCTCAAGCTCTACGGGATCCGCTTTGACATCCTTGTCACTGGGCAGGCAGGAAAGTTCGGGCT
CATTCCCACGACCATCACTCTGGGCACCGGAGCAGCTTGGCTGGGTGTGATCACCTTCCTCTGT
GACCTGCTGCTCTTGTACGTGGATGAAGAAGCCCATTTCTACTGGAGTACCAAGTATGAGGAGG
CAAAGGCCCCGAAGGTGACCACCACCCCTGAGCAGACAAAGCCAGCTTCTGCACCCCCCGCATG
CGGCTGCCCAGGTGTCTTAGAGGGGACCCAGTCTGGGAACCAGACACCAACAGCAGAGTGGCCG
TGCCTGGGCTCCGGCCCCCCCTCACCGGCCTGTTCCTGATGCCTGTGGCTGTTTGCTGCTGGGT
GCGGGGTGGGGGCCCCGTCTTGGGGACCTGCTGGATAAAGCCCCAGCAGGACTAGGGTGGGGGG
TTGGGGAAGAATCCCATCCTTCCACTCTCAGACAGGCTGTCCCTCCCCTGACACCAGCTTCAGC
AGGGTGCTGCCTGGGGAGCCACAGAAACCAGTTTTGCATAGAGACCCGCAGCAGAACATGAGTC
AAGAAGGGGAGACCCTAGGGCACCCATGTGGCAAGGCAGTGGTCCAGAGGGGCTCCTGCTATAT
CTAGGTCTAGAGAACTCTCTCCCAGTCTCTGTCACCATCAGTGCCCAGCAGCGGCCTGCTCACC
AGCTGTCAGCACCGGCCCTCCCACTGGCTGTAGCAGACTCCAGCCTTCCTTCCTCTGCTGAGAC
TCCTATTGTAGGCAGAGCCCCTCTTTCTCAGCTGTGCTGCACTGGGGTCTATGCAAACTGGAGT
CTGAAGCAAGGTAGAAAGAAGCCTGACTGGAGGGGTTGTCTCAGCTGCTCCAGTGCTGGGTTGC
CTGGGGCAGGTTCCTACCCAACTCTGGGCCTCATCCATGGAATGAAGAGTGGGTAGGCAGATGA
TCCAACCCCTAGGAACCTCAAGCAAGGGCACATCCTTTGGTCTCACACCTGCTCAGTTTATGAG
CATCAGCCCCTCCCTGGTGGTAGCCCTCAGGCTATGGGGCTTGGGAGAGGGAGGAGAGGGTGGG
GGGAGCTGAGATGGTGGTCACTAGGGCCTCTGGGATCTTCTGTATGCCTCTTCATTAACCGTCC
CCACATACACACACAAGCCCAACCCCTAGAACCTGCTCACCGGACCCATGGGGATAGGAGGCTG
TACATCTGGAATTCATTGCTACCTAGGGTCATATCTAAGAATGTGTCAGGACATCTGCTTGTCC
CAGCCTCAGGCAACTGCATTCAGGTGGCTTTGGTCATAACCCCCCACCCTAGAGCCCAGTGGCT
GGAAGGAATGTCCCTAACAAAGGACACAAAGGTTTCCAGCAGGCTGGCTTGGTATCATACTGGA
GAATTTCCCTTGCCCTGGAGTCCCCTGCCAGGACTCCCTGCCAGGAGGGGAGGAACAAGGGCTA
CAGGAGTCAAATGCCCTGTGGTTCCAGGGCAGAGGCAGGAATTTGGGAGTACCCACCCTAGGGA
AGTAAGGGGCTTCTCTCTCCTGGGTCTCTGGTGACCAAGGGTGTGCTGGCAGCTTGGTGGTGGA
GCAGCAAAGACCAGCTGGGGAGGGCCAGGGCTGGGGCTCAGGCTGGACTAGCATCTGGAATCAT
CTGACACCTGGAGCCTCAACAAAGCCTTGGGCTCCCTGCTGCTTCTCAATCCCCAGAGCAGTAT
CCATGGGGAGGCAGGTTCAGAAGAACCAAGGTGAGAGAACATGGCTCTGAGGCCTGGTTATCGG
AGTGGGGTCACATGTACCTAGTTGTCCTCGGGGTCCAGAGAAAGCTGTTATAACTGCAGAAAGT
CAAGGAGTAAAGCCTGCTAAAACCA

hide sequence

RefSeq Acc Id:

XM_038437592 ⟹ XP_038293520

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	26	31,867,789 - 31,879,013 (-)	NCBI

RefSeq Acc Id:

XM_038512455 ⟹ XP_038368383

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	26	29,913,614 - 29,924,837 (-)	NCBI

RefSeq Acc Id:

XM_038575955 ⟹ XP_038431883

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	26	30,626,779 - 30,638,005 (-)	NCBI

RefSeq Acc Id:

XM_038640165 ⟹ XP_038496093

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	26	29,537,801 - 29,549,022 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005636671	(Get FASTA)	NCBI Sequence Viewer
	XP_038293520	(Get FASTA)	NCBI Sequence Viewer
	XP_038368383	(Get FASTA)	NCBI Sequence Viewer
	XP_038431883	(Get FASTA)	NCBI Sequence Viewer
	XP_038496093	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000042799.3
	ENSCAFP00030038543.1
	ENSCAFP00040032527.1
	ENSCAFP00040032579.1
	ENSCAFP00845032288
	ENSCAFP00845032288.1

RefSeq Acc Id:

XP_005636671 ⟸ XM_005636614

- UniProtKB:

A0A8C0TCB2 (UniProtKB/TrEMBL), A0A8I3S3K0 (UniProtKB/TrEMBL), A0A8C0PAB1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGFPGVLAGWGLLDYKTEKYVITRNWRVGALQRLLQLGVMTYVVGWALLAKKGYQERDLDPQIS
VITKLKGVSVTQIKELGNRLWDVADFVKPPQGENTFFLVTNFLVTPEQVQDKCPEHPSIPLANC
WADEDCPEGETGTHSHGIKTGQCVEFNGTHRTCEIQGWCPVESGTVPVKPLLVQAENFTLFVKN
TVTFNKFNFSKSNALDTWDATYFKRCRYDSHYSPYCPVFRIGDLVAAAGGVFEDLALLGGAVGV
RVHWDCDLDAGASDCRPHYSFQLQERSYNFRTASHWWKASGVEARSLLKLYGIRFDILVTGQAG
KFGLIPTTITLGTGAAWLGVITFLCDLLLLYVDEEAHFYWSTKYEEAKAPKVTTTPEQTKPASA
PPACGCPGVLEGTQSGNQTPTAEWPCLGSGPPSPACS

hide sequence

RefSeq Acc Id:

ENSCAFP00000047916 ⟸ ENSCAFT00000078857

RefSeq Acc Id:

ENSCAFP00000042799 ⟸ ENSCAFT00000045106

RefSeq Acc Id:

ENSCAFP00000022204 ⟸ ENSCAFT00000023919

RefSeq Acc Id:

ENSCAFP00000044330 ⟸ ENSCAFT00000071547

RefSeq Acc Id:

XP_038368383 ⟸ XM_038512455

RefSeq Acc Id:

XP_038496093 ⟸ XM_038640165

RefSeq Acc Id:	XP_038293520 ⟸ XM_038437592
- UniProtKB:	A0A8C0TCB2 (UniProtKB/TrEMBL), A0A8I3S3K0 (UniProtKB/TrEMBL), A0A8C0PAB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038431883 ⟸ XM_038575955
- UniProtKB:	A0A8C0PAB1 (UniProtKB/TrEMBL), A0A8C0TCB2 (UniProtKB/TrEMBL), A0A8I3S3K0 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845032288 ⟸ ENSCAFT00845041196

Promoters

RGD ID:

13688047

Promoter ID:

EPDNEW_C6115

Type:

single initiation site

Name:

P2RX6_1

Description:

purinergic receptor P2X 6

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	26	30,457,078 - 30,457,138	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000015060	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030024005	UniProtKB/TrEMBL
	ENSCAFG00040020184	UniProtKB/TrEMBL
	ENSCAFG00845023336	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000045106.4	UniProtKB/TrEMBL
	ENSCAFT00030044166.1	UniProtKB/TrEMBL
	ENSCAFT00040037324.1	UniProtKB/TrEMBL
	ENSCAFT00040037384.1	UniProtKB/TrEMBL
	ENSCAFT00845041196	ENTREZGENE
	ENSCAFT00845041196.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.490.10	UniProtKB/TrEMBL
	atp-gated p2x4 ion channel	UniProtKB/TrEMBL
InterPro	P2X6_purnocptor	UniProtKB/TrEMBL
	P2X_extracellular_dom_sf	UniProtKB/TrEMBL
	P2X_purnocptor	UniProtKB/TrEMBL
KEGG Report	cfa:486436	UniProtKB/TrEMBL
NCBI Gene	P2RX6	ENTREZGENE
PANTHER	P2X PURINOCEPTOR	UniProtKB/TrEMBL
	PTHR10125:SF21	UniProtKB/TrEMBL
Pfam	P2X_receptor	UniProtKB/TrEMBL
PIRSF	P2X_purinoceptor	UniProtKB/TrEMBL
PRINTS	P2X6RECEPTOR	UniProtKB/TrEMBL
	P2XRECEPTOR	UniProtKB/TrEMBL
PROSITE	P2X_RECEPTOR	UniProtKB/TrEMBL
UniProt	A0A8C0PAB1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0TCB2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0Z2V8_CANLF	UniProtKB/TrEMBL
	A0A8I3S3K0	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:44211	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar