KCNG3 (potassium voltage-gated channel modifier subfamily G member 3) - Rat Genome Database

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Gene: KCNG3 (potassium voltage-gated channel modifier subfamily G member 3) Canis lupus familiaris
Analyze
Symbol: KCNG3
Name: potassium voltage-gated channel modifier subfamily G member 3
RGD ID: 12288563
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity (inferred); monoatomic ion channel activity (inferred); potassium channel activity (inferred); INVOLVED IN potassium ion transport (ortholog); ASSOCIATED WITH genetic disease (ortholog); Lynch syndrome (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily G member 3; potassium voltage-gated channel, subfamily G, member 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11733,999,911 - 34,080,415 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,022,261 - 34,080,603 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1733,804,516 - 33,851,663 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01734,802,688 - 34,850,084 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11733,927,604 - 33,975,280 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01733,989,902 - 34,037,224 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,207,516 - 34,255,093 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNG3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11733,999,911 - 34,080,415 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,022,261 - 34,080,603 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1733,804,516 - 33,851,663 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01734,802,688 - 34,850,084 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11733,927,604 - 33,975,280 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01733,989,902 - 34,037,224 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,207,516 - 34,255,093 (-)NCBIUU_Cfam_GSD_1.0
KCNG3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38242,388,352 - 42,493,982 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl242,442,017 - 42,493,982 (-)EnsemblGRCh38hg38GRCh38
GRCh37242,669,157 - 42,721,122 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36242,522,661 - 42,574,741 (-)NCBINCBI36Build 36hg18NCBI36
Build 34242,580,807 - 42,632,888NCBI
Celera242,509,472 - 42,561,403 (-)NCBICelera
Cytogenetic Map2p21NCBI
HuRef242,403,435 - 42,455,714 (-)NCBIHuRef
CHM1_1242,598,567 - 42,650,647 (-)NCBICHM1_1
T2T-CHM13v2.0242,393,706 - 42,499,421 (-)NCBIT2T-CHM13v2.0
Kcng3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391783,881,452 - 83,939,595 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1783,893,386 - 83,939,324 (-)EnsemblGRCm39 Ensembl
GRCm381783,574,023 - 83,631,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1783,585,957 - 83,631,895 (-)EnsemblGRCm38mm10GRCm38
MGSCv371783,985,297 - 84,031,235 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361783,494,283 - 83,540,221 (-)NCBIMGSCv36mm8
Celera1787,928,594 - 87,993,545 (-)NCBICelera
Cytogenetic Map17E4NCBI
cM Map1753.64NCBI
Kcng3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8616,803,842 - 16,851,791 (+)NCBIGRCr8
mRatBN7.2611,051,311 - 11,099,264 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl611,051,134 - 11,099,264 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx611,345,533 - 11,393,536 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0611,654,858 - 11,702,861 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0611,167,797 - 11,215,815 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.066,794,808 - 6,842,758 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl66,794,808 - 6,842,758 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.066,749,225 - 6,797,221 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.466,947,526 - 6,995,735 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.166,947,767 - 6,995,429 (-)NCBI
Celera610,756,043 - 10,803,960 (+)NCBICelera
Cytogenetic Map6q12NCBI
Kcng3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554419,816,209 - 9,860,707 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554419,813,391 - 9,859,960 (-)NCBIChiLan1.0ChiLan1.0
KCNG3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21283,914,398 - 84,019,873 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A83,918,371 - 84,023,846 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A42,513,259 - 42,593,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A43,392,545 - 43,443,078 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A43,392,545 - 43,443,084 (-)Ensemblpanpan1.1panPan2
Kcng3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629237,750,522 - 37,787,396 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365089,178,964 - 9,220,221 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365089,179,131 - 9,216,996 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNG3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl397,830,678 - 97,885,064 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1397,830,795 - 97,887,582 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23103,965,694 - 104,021,093 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KCNG3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11464,756,221 - 64,812,337 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1464,756,825 - 64,810,421 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604547,094,441 - 47,151,636 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcng3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473824,130,784 - 24,173,631 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473824,127,981 - 24,173,728 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in KCNG3
892 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 6 8
Low 5 12 3 1 3 5 6 9 1
Below cutoff 5 4 3 5 3 1 6 1 5

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003432199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014120549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014120550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014120551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404667 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022404672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038498795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038498796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038561354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038561355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038625405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038625406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038691336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038691337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_858942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002615255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002615256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002615257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000010528   ⟹   ENSCAFP00000009759
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1734,035,423 - 34,080,603 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000091016   ⟹   ENSCAFP00000065291
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1734,022,261 - 34,080,603 (-)Ensembl
RefSeq Acc Id: XM_003432199   ⟹   XP_003432247
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11734,033,291 - 34,080,415 (-)NCBI
Dog10K_Boxer_Tasha1733,804,516 - 33,851,663 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038498795   ⟹   XP_038354723
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11733,927,604 - 33,975,280 (-)NCBI
RefSeq Acc Id: XM_038498796   ⟹   XP_038354724
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11733,927,606 - 33,975,280 (-)NCBI
RefSeq Acc Id: XM_038561354   ⟹   XP_038417282
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01734,207,516 - 34,255,093 (-)NCBI
RefSeq Acc Id: XM_038561355   ⟹   XP_038417283
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01734,207,518 - 34,255,093 (-)NCBI
RefSeq Acc Id: XM_038625405   ⟹   XP_038481333
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01733,989,902 - 34,037,224 (-)NCBI
RefSeq Acc Id: XM_038625406   ⟹   XP_038481334
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01733,989,904 - 34,037,224 (-)NCBI
RefSeq Acc Id: XM_038691336   ⟹   XP_038547264
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01734,802,688 - 34,850,084 (-)NCBI
RefSeq Acc Id: XM_038691337   ⟹   XP_038547265
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01734,802,690 - 34,850,084 (-)NCBI
RefSeq Acc Id: XM_858942   ⟹   XP_864035
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11734,033,292 - 34,080,415 (-)NCBI
Dog10K_Boxer_Tasha1733,804,518 - 33,851,663 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_864035   ⟸   XM_858942
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TU63 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003432247   ⟸   XM_003432199
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R5A3 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000009759   ⟸   ENSCAFT00000010528
RefSeq Acc Id: ENSCAFP00000065291   ⟸   ENSCAFT00000091016
RefSeq Acc Id: XP_038354723   ⟸   XM_038498795
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038354724   ⟸   XM_038498796
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038481333   ⟸   XM_038625405
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038481334   ⟸   XM_038625406
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038547264   ⟸   XM_038691336
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R5A3 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038547265   ⟸   XM_038691337
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TU63 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038417282   ⟸   XM_038561354
- Peptide Label: isoform X1
- UniProtKB: A0A8C0R5A3 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038417283   ⟸   XM_038561355
- Peptide Label: isoform X2
- UniProtKB: A0A8C0TU63 (UniProtKB/TrEMBL),   A0A8P0N8Y8 (UniProtKB/TrEMBL)
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000006520 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030010962 UniProtKB/TrEMBL
  ENSCAFG00040025591 UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000010528.5 UniProtKB/TrEMBL
  ENSCAFT00000091016.2 UniProtKB/TrEMBL
  ENSCAFT00030020422.1 UniProtKB/TrEMBL
  ENSCAFT00040047771.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv6 UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv9 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
NCBI Gene KCNG3 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY G MEMBER 3 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KV6CHANNEL UniProtKB/TrEMBL
  KV9CHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A8C0R5A3 ENTREZGENE
  A0A8C0TU63 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0N8Y8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0PDV2_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:42246 ENTREZGENE