FOXN1 (forkhead box N1) - Rat Genome Database

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Gene: FOXN1 (forkhead box N1) Canis lupus familiaris
Analyze
Symbol: FOXN1
Name: forkhead box N1
RGD ID: 12286475
Description: ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN epidermis development (ortholog); hair follicle development (ortholog); keratinocyte differentiation (ortholog); ASSOCIATED WITH alopecia (ortholog); autistic disorder (ortholog); DiGeorge syndrome (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: forkhead box protein N1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,734,228 - 42,749,856 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,735,656 - 42,748,632 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,878,088 - 41,906,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,540,303 - 43,568,825 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,540,213 - 43,567,599 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,323,418 - 42,351,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,615,833 - 42,644,325 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,693,335 - 42,721,782 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FOXN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1942,734,228 - 42,749,856 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl942,735,656 - 42,748,632 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha941,878,088 - 41,906,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0943,540,303 - 43,568,825 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl943,540,213 - 43,567,599 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1942,323,418 - 42,351,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0942,615,833 - 42,644,325 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0942,693,335 - 42,721,782 (+)NCBIUU_Cfam_GSD_1.0
FOXN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381728,506,348 - 28,538,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1728,506,243 - 28,538,900 (+)EnsemblGRCh38hg38GRCh38
GRCh371726,833,366 - 26,865,918 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361723,875,086 - 23,889,302 (+)NCBINCBI36Build 36hg18NCBI36
Build 341723,875,085 - 23,889,302NCBI
Celera1723,709,983 - 23,724,203 (+)NCBICelera
Cytogenetic Map17q11.2NCBI
HuRef1723,059,775 - 23,073,995 (+)NCBIHuRef
CHM1_11726,912,657 - 26,926,877 (+)NCBICHM1_1
T2T-CHM13v2.01729,449,365 - 29,481,520 (+)NCBIT2T-CHM13v2.0
Foxn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,248,403 - 78,277,597 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,248,403 - 78,277,384 (-)EnsemblGRCm39 Ensembl
GRCm381178,357,577 - 78,386,783 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,357,577 - 78,386,558 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,171,790 - 78,200,060 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361178,174,483 - 78,202,753 (-)NCBIMGSCv36mm8
Celera1187,990,370 - 88,018,640 (-)NCBICelera
Cytogenetic Map11B5NCBI
cM Map1146.74NCBI
Foxn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81063,749,461 - 63,778,468 (-)NCBIGRCr8
mRatBN7.21063,251,400 - 63,273,710 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1063,251,400 - 63,273,710 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1067,883,721 - 67,906,099 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01067,389,050 - 67,411,428 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01062,860,147 - 62,882,662 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01065,621,142 - 65,634,666 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1065,621,257 - 65,634,666 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01066,004,940 - 66,030,134 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,243,323 - 64,256,847 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1062,229,663 - 62,243,188 (-)NCBICelera
Cytogenetic Map10q25NCBI
Foxn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554814,611,087 - 4,627,113 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554814,611,246 - 4,640,606 (-)NCBIChiLan1.0ChiLan1.0
FOXN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21935,921,399 - 35,954,659 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11737,801,555 - 37,834,927 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01728,237,150 - 28,272,010 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11728,740,775 - 28,773,592 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1728,740,775 - 28,773,592 (-)Ensemblpanpan1.1panPan2
Foxn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560241,839,546 - 41,868,057 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365384,731,958 - 4,744,796 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365384,717,509 - 4,745,504 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1244,765,258 - 44,795,260 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11244,764,427 - 44,796,138 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21246,757,094 - 46,780,509 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FOXN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11622,291,597 - 22,306,977 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1622,292,330 - 22,305,968 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660757,819,856 - 7,835,084 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247861,114,305 - 1,127,683 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247861,114,305 - 1,127,787 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in FOXN1
166 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 4
Low 2 8
Below cutoff 5 5 21 5 6 5 2 11 10 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029700   ⟹   ENSCAFP00000027604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl942,735,656 - 42,748,632 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845013248   ⟹   ENSCAFP00845010292
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl943,540,213 - 43,567,599 (+)Ensembl
RefSeq Acc Id: XM_022423338   ⟹   XP_022279046
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1942,734,228 - 42,749,856 (+)NCBI
Dog10K_Boxer_Tasha941,892,284 - 41,906,518 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038486396   ⟹   XP_038342324
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1942,323,418 - 42,351,882 (+)NCBI
RefSeq Acc Id: XM_038486397   ⟹   XP_038342325
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1942,337,652 - 42,351,882 (+)NCBI
RefSeq Acc Id: XM_038548234   ⟹   XP_038404162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0942,693,335 - 42,721,782 (+)NCBI
RefSeq Acc Id: XM_038548235   ⟹   XP_038404163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0942,707,547 - 42,721,782 (+)NCBI
RefSeq Acc Id: XM_038610583   ⟹   XP_038466511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha941,878,088 - 41,906,518 (+)NCBI
RefSeq Acc Id: XM_038612200   ⟹   XP_038468128
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0942,615,833 - 42,644,325 (+)NCBI
RefSeq Acc Id: XM_038612201   ⟹   XP_038468129
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0942,630,098 - 42,644,325 (+)NCBI
RefSeq Acc Id: XM_038677457   ⟹   XP_038533385
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0943,540,303 - 43,568,825 (+)NCBI
RefSeq Acc Id: XM_038677459   ⟹   XP_038533387
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0943,554,584 - 43,568,825 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_022279046   ⟸   XM_022423338
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000027604   ⟸   ENSCAFT00000029700
RefSeq Acc Id: XP_038342324   ⟸   XM_038486396
RefSeq Acc Id: XP_038342325   ⟸   XM_038486397
RefSeq Acc Id: XP_038468128   ⟸   XM_038612200
RefSeq Acc Id: XP_038468129   ⟸   XM_038612201
RefSeq Acc Id: XP_038533385   ⟸   XM_038677457
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038533387   ⟸   XM_038677459
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038466511   ⟸   XM_038610583
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404162   ⟸   XM_038548234
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038404163   ⟸   XM_038548235
- UniProtKB: A0A8C0NAB4 (UniProtKB/TrEMBL),   A0A8I3RVF1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845010292   ⟸   ENSCAFT00845013248
Protein Domains
Fork-head


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018709 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030013346 UniProtKB/TrEMBL
  ENSCAFG00040020402 UniProtKB/TrEMBL
  ENSCAFG00845007518 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029700.4 UniProtKB/TrEMBL
  ENSCAFT00030024805.1 UniProtKB/TrEMBL
  ENSCAFT00040037745.1 UniProtKB/TrEMBL
  ENSCAFT00845013248 ENTREZGENE
  ENSCAFT00845013248.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
InterPro FH_FOXN1 UniProtKB/TrEMBL
  Fork_head_dom UniProtKB/TrEMBL
  FOXN1_4 UniProtKB/TrEMBL
  TF_fork_head_CS_2 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene FOXN1 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN N1 UniProtKB/TrEMBL
  FORKHEAD BOX PROTEIN N1 UniProtKB/TrEMBL
Pfam Forkhead UniProtKB/TrEMBL
PRINTS FORKHEAD UniProtKB/TrEMBL
PROSITE FORK_HEAD_2 UniProtKB/TrEMBL
  FORK_HEAD_3 UniProtKB/TrEMBL
SMART SM00339 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
UniProt A0A8C0NAB4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RVF1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NJZ4_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:40960 ENTREZGENE