PDC (phosducin) - Rat Genome Database

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Pathways
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Gene: PDC (phosducin) Canis lupus familiaris
Analyze
Symbol: PDC
Name: phosducin
RGD ID: 12282587
Description: INVOLVED IN regulation of G protein-coupled receptor signaling pathway (inferred); visual perception (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); parathyroid carcinoma (ortholog); FOUND IN cilium (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 33 kDa phototransducing protein; pdc gene for phosducin; PHD
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1719,498,785 - 19,514,225 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl719,498,788 - 19,514,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha719,020,407 - 19,035,847 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0719,234,869 - 19,250,306 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl719,234,872 - 19,250,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1719,141,771 - 19,157,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0719,251,031 - 19,266,481 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0719,382,072 - 19,397,756 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:9714819   PMID:11401471   PMID:12091798   PMID:18724412   PMID:22301074  


Genomics

Comparative Map Data
PDC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1719,498,785 - 19,514,225 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl719,498,788 - 19,514,228 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha719,020,407 - 19,035,847 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0719,234,869 - 19,250,306 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl719,234,872 - 19,250,306 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1719,141,771 - 19,157,188 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0719,251,031 - 19,266,481 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0719,382,072 - 19,397,756 (-)NCBIUU_Cfam_GSD_1.0
PDC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381186,443,566 - 186,461,114 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1186,443,566 - 186,461,114 (-)EnsemblGRCh38hg38GRCh38
GRCh371186,412,698 - 186,430,246 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361184,679,337 - 184,696,862 (-)NCBINCBI36Build 36hg18NCBI36
Build 341183,144,373 - 183,161,896NCBI
Celera1159,523,438 - 159,540,966 (-)NCBICelera
Cytogenetic Map1q31.1NCBI
HuRef1157,647,242 - 157,664,785 (-)NCBIHuRef
CHM1_11187,834,441 - 187,851,962 (-)NCBICHM1_1
T2T-CHM13v2.01185,798,329 - 185,815,896 (-)NCBIT2T-CHM13v2.0
Pdc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391150,195,168 - 150,209,657 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1150,195,168 - 150,209,657 (+)EnsemblGRCm39 Ensembl
GRCm381150,319,417 - 150,333,906 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1150,319,417 - 150,333,906 (+)EnsemblGRCm38mm10GRCm38
MGSCv371152,166,547 - 152,181,036 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361152,081,635 - 152,096,124 (+)NCBIMGSCv36mm8
Celera1152,758,050 - 152,772,537 (+)NCBICelera
Cytogenetic Map1G1NCBI
cM Map163.84NCBI
Pdc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81364,847,366 - 64,921,865 (+)NCBIGRCr8
mRatBN7.21362,297,281 - 62,371,754 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1362,358,196 - 62,371,754 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1364,998,016 - 65,011,575 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01366,275,990 - 66,289,477 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01363,537,222 - 63,550,763 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01367,545,430 - 67,558,600 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1367,545,430 - 67,558,600 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01372,510,251 - 72,523,421 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41364,622,473 - 64,636,031 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11364,636,552 - 64,650,111 (+)NCBI
Celera1362,323,686 - 62,337,185 (+)NCBICelera
Cytogenetic Map13q21NCBI
Pdc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540624,857,642 - 24,873,307 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540624,857,791 - 24,873,057 (-)NCBIChiLan1.0ChiLan1.0
PDC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2163,270,733 - 63,283,638 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1162,952,116 - 62,965,009 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01161,969,161 - 161,976,816 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11166,122,181 - 166,145,947 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1166,122,181 - 166,145,947 (-)Ensemblpanpan1.1panPan2
Pdc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934486,128,092 - 86,148,682 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364813,974,682 - 3,995,423 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364813,974,831 - 3,995,431 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9127,601,385 - 127,619,697 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19127,600,114 - 127,619,759 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29140,053,493 - 140,073,532 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12542,983,682 - 42,990,191 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2542,984,036 - 42,989,769 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605544,170,667 - 44,179,290 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248147,190,805 - 7,198,229 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248147,150,941 - 7,198,327 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PDC
172 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6
Low 2
Below cutoff 2 3 8 3 3 3 2 4 7 6 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF046874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ417559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ417560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ417561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ429100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN875889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN876272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN876673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y17697 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000021818   ⟹   ENSCAFP00000020267
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl719,498,788 - 19,514,228 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845009526   ⟹   ENSCAFP00845007448
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl719,234,872 - 19,250,306 (-)Ensembl
RefSeq Acc Id: NM_001003076   ⟹   NP_001003076
RefSeq Status: VALIDATED
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1719,498,785 - 19,514,225 (-)NCBI
Dog10K_Boxer_Tasha719,020,407 - 19,035,847 (-)NCBI
ROS_Cfam_1.0719,234,871 - 19,250,306 (-)NCBI
UMICH_Zoey_3.1719,141,771 - 19,157,188 (-)NCBI
UNSW_CanFamBas_1.0719,251,031 - 19,266,481 (-)NCBI
UU_Cfam_GSD_1.0719,382,072 - 19,397,756 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038670482   ⟹   XP_038526410
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0719,234,869 - 19,239,839 (-)NCBI
RefSeq Acc Id: XM_038670483   ⟹   XP_038526411
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0719,234,869 - 19,239,839 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001003076   ⟸   NM_001003076
- UniProtKB: O77560 (UniProtKB/Swiss-Prot),   Q9TSE3 (UniProtKB/Swiss-Prot),   A0A8C0KVW1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000020267   ⟸   ENSCAFT00000021818
RefSeq Acc Id: XP_038526411   ⟸   XM_038670483
- Peptide Label: isoform X1
- UniProtKB: O77560 (UniProtKB/Swiss-Prot),   Q9TSE3 (UniProtKB/Swiss-Prot),   A0A8C0KVW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038526410   ⟸   XM_038670482
- Peptide Label: isoform X1
- UniProtKB: O77560 (UniProtKB/Swiss-Prot),   Q9TSE3 (UniProtKB/Swiss-Prot),   A0A8C0KVW1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845007448   ⟸   ENSCAFT00845009526


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013751 Ensembl, UniProtKB/Swiss-Prot
  ENSCAFG00030000579 UniProtKB/Swiss-Prot
  ENSCAFG00040005240 UniProtKB/Swiss-Prot
  ENSCAFG00805020301 UniProtKB/Swiss-Prot
  ENSCAFG00845005358 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSCAFT00000021818.4 UniProtKB/Swiss-Prot
  ENSCAFT00030000954.1 UniProtKB/Swiss-Prot
  ENSCAFT00040009818.1 UniProtKB/Swiss-Prot
  ENSCAFT00805036722 UniProtKB/Swiss-Prot
  ENSCAFT00845009526 ENTREZGENE
  ENSCAFT00845009526.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.168.10 UniProtKB/Swiss-Prot
  Glutaredoxin UniProtKB/Swiss-Prot
InterPro Phosducin UniProtKB/Swiss-Prot
  Phosducin_N_dom_sf UniProtKB/Swiss-Prot
  Phosducin_thioredoxin-like_dom UniProtKB/Swiss-Prot
  Thioredoxin-like_sf UniProtKB/Swiss-Prot
KEGG Report cfa:403624 UniProtKB/Swiss-Prot
NCBI Gene PDC ENTREZGENE
PANTHER PHOSDUCIN UniProtKB/Swiss-Prot
  PHOSDUCIN-LIKE PROTEIN UniProtKB/Swiss-Prot
Pfam Phosducin UniProtKB/Swiss-Prot
PRINTS PHOSDUCIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot
UniProt A0A8C0KVW1 ENTREZGENE
  O77560 ENTREZGENE, UniProtKB/Swiss-Prot
  Q9TSE3 ENTREZGENE
UniProt Secondary Q9TSE3 UniProtKB/Swiss-Prot
VGNC ID VGNC:44333 ENTREZGENE