AHSG (alpha 2-HS glycoprotein) - Rat Genome Database

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Gene: AHSG (alpha 2-HS glycoprotein) Canis lupus familiaris
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Symbol: AHSG
Name: alpha 2-HS glycoprotein
RGD ID: 12259193
Description: ENCODES a protein that exhibits receptor signaling protein tyrosine kinase inhibitor activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to insulin stimulus (ortholog); cerebral cortex development (ortholog); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); acute kidney failure (ortholog); alopecia-mental retardation syndrome 1 (ortholog); FOUND IN collagen-containing extracellular matrix (ortholog); extracellular space (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-2-HS-glycoprotein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,221,034 - 19,228,866 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,221,107 - 19,228,716 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,306,490 - 23,314,279 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,131,902 - 19,139,692 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,127,667 - 19,139,688 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,158,092 - 19,165,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,164,067 - 19,171,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,392,722 - 19,400,512 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
AHSG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,221,034 - 19,228,866 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,221,107 - 19,228,716 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,306,490 - 23,314,279 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03419,131,902 - 19,139,692 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3419,127,667 - 19,139,688 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13419,158,092 - 19,165,882 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03419,164,067 - 19,171,857 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03419,392,722 - 19,400,512 (+)NCBIUU_Cfam_GSD_1.0
AHSG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,613,060 - 186,621,318 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3186,613,060 - 186,621,318 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,330,849 - 186,339,107 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,813,544 - 187,821,801 (+)NCBINCBI36Build 36hg18NCBI36
Build 343187,813,588 - 187,821,807NCBI
Celera3184,767,234 - 184,775,491 (+)NCBICelera
Cytogenetic Map3q27.3NCBI
HuRef3183,739,917 - 183,748,174 (+)NCBIHuRef
CHM1_13186,294,812 - 186,303,069 (+)NCBICHM1_1
T2T-CHM13v2.03189,428,789 - 189,437,047 (+)NCBIT2T-CHM13v2.0
Ahsg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,710,793 - 22,718,193 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1622,710,027 - 22,718,199 (+)EnsemblGRCm39 Ensembl
GRCm381622,892,015 - 22,899,451 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,891,277 - 22,899,449 (+)EnsemblGRCm38mm10GRCm38
MGSCv371622,892,115 - 22,899,511 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361622,807,376 - 22,814,772 (+)NCBIMGSCv36mm8
Celera1623,452,367 - 23,459,763 (+)NCBICelera
Cytogenetic Map16B1NCBI
cM Map1613.74NCBI
Ahsg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,625,975 - 91,632,583 (-)NCBIGRCr8
mRatBN7.21178,121,388 - 78,127,998 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1178,117,918 - 78,145,999 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1186,871,860 - 86,878,457 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01179,523,661 - 79,530,222 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,586,170 - 78,592,769 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01181,711,269 - 81,717,594 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,799,840 - 84,805,423 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,330,615 - 80,336,658 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11180,388,229 - 80,394,247 (-)NCBI
Celera1176,992,913 - 76,998,938 (-)NCBICelera
Cytogenetic Map11q23NCBI
Ahsg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542021,069,681 - 21,078,298 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542021,071,111 - 21,078,397 (-)NCBIChiLan1.0ChiLan1.0
AHSG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22184,485,324 - 184,494,432 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13184,490,039 - 184,499,137 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03183,644,223 - 183,652,620 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13192,111,528 - 192,119,915 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,110,770 - 192,119,915 (+)Ensemblpanpan1.1panPan2
Ahsg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,240,708 - 117,248,141 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365783,332,934 - 3,339,903 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365783,332,934 - 3,339,903 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AHSG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,426,308 - 124,438,840 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,426,313 - 124,438,848 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,821,515 - 133,828,640 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AHSG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1152,809,234 - 2,818,382 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl152,809,028 - 2,817,514 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606311,551,731 - 11,560,628 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ahsg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473070,149,850 - 70,156,039 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473070,149,461 - 70,156,058 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in AHSG
239 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High 6 6 6
Medium
Low 1 1 2 2 6 3 1
Below cutoff 4 3 12 3 4 1 6 8 3 4

Sequence


RefSeq Acc Id: ENSCAFT00000021520   ⟹   ENSCAFP00000019983
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl3419,221,107 - 19,228,716 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845036475   ⟹   ENSCAFP00845028548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl3419,127,667 - 19,139,688 (+)Ensembl
RefSeq Acc Id: XM_005639808   ⟹   XP_005639865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13419,221,034 - 19,228,866 (+)NCBI
Dog10K_Boxer_Tasha3423,306,490 - 23,314,279 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038445820   ⟹   XP_038301748
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.03419,131,902 - 19,139,692 (+)NCBI
RefSeq Acc Id: XM_038520016   ⟹   XP_038375944
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.13419,158,092 - 19,165,882 (+)NCBI
RefSeq Acc Id: XM_038583641   ⟹   XP_038439569
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.03419,392,722 - 19,400,512 (+)NCBI
RefSeq Acc Id: XM_038648058   ⟹   XP_038503986
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.03419,164,067 - 19,171,857 (+)NCBI
RefSeq Acc Id: XP_005639865   ⟸   XM_005639808
- UniProtKB: A0A8C0JYJ5 (UniProtKB/TrEMBL),   A0A8C0P2U0 (UniProtKB/TrEMBL),   A0A8I3PIK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000019983   ⟸   ENSCAFT00000021520
RefSeq Acc Id: XP_038375944   ⟸   XM_038520016
RefSeq Acc Id: XP_038503986   ⟸   XM_038648058
RefSeq Acc Id: XP_038301748   ⟸   XM_038445820
- UniProtKB: A0A8C0JYJ5 (UniProtKB/TrEMBL),   A0A8C0P2U0 (UniProtKB/TrEMBL),   A0A8I3PIK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038439569   ⟸   XM_038583641
- UniProtKB: A0A8C0JYJ5 (UniProtKB/TrEMBL),   A0A8C0P2U0 (UniProtKB/TrEMBL),   A0A8I3PIK8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845028548   ⟸   ENSCAFT00845036475
Protein Domains
Cystatin fetuin-A-type

Promoters
RGD ID:13688910
Promoter ID:EPDNEW_C6978
Type:multiple initiation site
Name:AHSG_1
Description:alpha 2-HS glycoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.13419,221,099 - 19,221,159EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000013568 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030020839 UniProtKB/TrEMBL
  ENSCAFG00040016655 UniProtKB/TrEMBL
  ENSCAFG00845020692 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000021520.5 UniProtKB/TrEMBL
  ENSCAFT00030038263.1 UniProtKB/TrEMBL
  ENSCAFT00040030757.1 UniProtKB/TrEMBL
  ENSCAFT00845036475 ENTREZGENE
  ENSCAFT00845036475.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.450.10 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Cystatin_Fetuin_A UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
  Prot_inh_fetuin_CS UniProtKB/TrEMBL
KEGG Report cfa:607538 UniProtKB/TrEMBL
NCBI Gene AHSG ENTREZGENE
PANTHER ALPHA-2-HS-GLYCOPROTEIN UniProtKB/TrEMBL
  FETUIN UniProtKB/TrEMBL
Pfam Cystatin UniProtKB/TrEMBL
PROSITE CYSTATIN_FETUIN_A UniProtKB/TrEMBL
  FETUIN_1 UniProtKB/TrEMBL
  FETUIN_2 UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt A0A8C0JYJ5 ENTREZGENE
  A0A8C0P2U0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PIK8 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:37731 ENTREZGENE