GPR119 (G protein-coupled receptor 119) - Rat Genome Database

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Gene: GPR119 (G protein-coupled receptor 119) Canis lupus familiaris
Analyze
Symbol: GPR119
Name: G protein-coupled receptor 119
RGD ID: 12229927
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); phosphatidylcholine binding (inferred); INVOLVED IN insulin secretion (ortholog); ASSOCIATED WITH autistic disorder (ortholog); genetic disease (ortholog); syndromic X-linked intellectual disability Lubs type (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: glucose-dependent insulinotropic receptor
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,518,313 - 101,520,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX101,518,977 - 101,519,984 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,692,390 - 87,698,073 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X103,374,107 - 103,379,790 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX103,378,287 - 103,379,294 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,788,832 - 100,794,515 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,634,515 - 102,640,198 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X102,413,036 - 102,418,383 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GPR119
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X101,518,313 - 101,520,677 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX101,518,977 - 101,519,984 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX87,692,390 - 87,698,073 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X103,374,107 - 103,379,790 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX103,378,287 - 103,379,294 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X100,788,832 - 100,794,515 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X102,634,515 - 102,640,198 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X102,413,036 - 102,418,383 (-)NCBIUU_Cfam_GSD_1.0
GPR119
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X130,379,449 - 130,385,674 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX130,379,449 - 130,385,674 (-)EnsemblGRCh38hg38GRCh38
GRCh37X129,513,423 - 129,519,648 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X129,346,095 - 129,347,102 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X129,243,948 - 129,244,956NCBI
CeleraX129,904,784 - 129,905,976 (-)NCBICelera
Cytogenetic MapXq26.1NCBI
HuRefX118,912,749 - 118,913,941 (-)NCBIHuRef
CHM1_1X129,429,952 - 129,431,144 (-)NCBICHM1_1
T2T-CHM13v2.0X128,698,231 - 128,704,458 (-)NCBIT2T-CHM13v2.0
Gpr119
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X47,756,856 - 47,763,355 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX47,756,856 - 47,763,355 (-)EnsemblGRCm39 Ensembl
GRCm38X48,667,979 - 48,674,478 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX48,667,979 - 48,674,478 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X46,021,156 - 46,027,655 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X44,917,878 - 44,918,885 (-)NCBIMGSCv36mm8
CeleraX36,171,845 - 36,178,348 (-)NCBICelera
Cytogenetic MapXA5NCBI
cM MapX25.69NCBI
Gpr119
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X132,730,027 - 132,736,080 (-)NCBIGRCr8
mRatBN7.2X127,852,145 - 127,858,198 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX127,852,145 - 127,858,198 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX129,977,934 - 129,983,962 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X133,548,684 - 133,554,737 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X131,075,102 - 131,081,130 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X135,515,545 - 135,521,598 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX135,515,545 - 135,521,598 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X135,585,869 - 135,591,922 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X135,080,163 - 135,086,216 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X135,153,595 - 135,159,649 (-)NCBI
CeleraX126,800,234 - 126,806,174 (-)NCBICelera
Cytogenetic MapXq36NCBI
Gpr119
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554734,686,225 - 4,687,232 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554734,686,225 - 4,687,232 (+)NCBIChiLan1.0ChiLan1.0
GPR119
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X129,800,132 - 129,806,361 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X129,803,746 - 129,809,975 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X119,511,372 - 119,512,611 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X129,803,294 - 129,804,512 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX129,803,383 - 129,804,390 (-)Ensemblpanpan1.1panPan2
Gpr119
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X99,723,913 - 99,725,096 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364791,262,484 - 1,263,491 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364791,262,399 - 1,263,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GPR119
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX106,872,225 - 106,873,299 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X106,872,225 - 106,873,299 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X122,640,688 - 122,641,762 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GPR119
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X105,641,691 - 105,646,692 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX105,644,002 - 105,645,009 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606543,063,792 - 43,065,043 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gpr119
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247979,664,216 - 9,665,220 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247979,664,097 - 9,666,243 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GPR119
4 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 2 2
Below cutoff 4 2 15 2 4 2 3 2 10 7 7 4

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000029782   ⟹   ENSCAFP00000027678
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 EnsemblX101,518,977 - 101,519,984 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845055196   ⟹   ENSCAFP00845043411
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 EnsemblX103,378,287 - 103,379,294 (-)Ensembl
RefSeq Acc Id: XM_022415876   ⟹   XP_022271584
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1X101,518,313 - 101,520,677 (-)NCBI
Dog10K_Boxer_TashaX87,692,390 - 87,698,073 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038450852   ⟹   XP_038306780
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0X103,374,107 - 103,379,790 (-)NCBI
RefSeq Acc Id: XM_038524321   ⟹   XP_038380249
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1X100,788,832 - 100,794,515 (-)NCBI
RefSeq Acc Id: XM_038588293   ⟹   XP_038444221
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0X102,413,036 - 102,418,383 (-)NCBI
RefSeq Acc Id: XM_038652813   ⟹   XP_038508741
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0X102,634,515 - 102,640,198 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_022271584   ⟸   XM_022415876
- UniProtKB: A0A8C0THM6 (UniProtKB/TrEMBL),   A0A8C0JJB9 (UniProtKB/TrEMBL),   A0A8I3QZL6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000027678   ⟸   ENSCAFT00000029782
RefSeq Acc Id: XP_038380249   ⟸   XM_038524321
RefSeq Acc Id: XP_038508741   ⟸   XM_038652813
RefSeq Acc Id: XP_038306780   ⟸   XM_038450852
- UniProtKB: A0A8C0THM6 (UniProtKB/TrEMBL),   A0A8C0JJB9 (UniProtKB/TrEMBL),   A0A8I3QZL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038444221   ⟸   XM_038588293
- UniProtKB: A0A8C0JJB9 (UniProtKB/TrEMBL),   A0A8C0THM6 (UniProtKB/TrEMBL),   A0A8I3QZL6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845043411   ⟸   ENSCAFT00845055196
Protein Domains
G-protein coupled receptors family 1 profile


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000018768 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030011799 UniProtKB/TrEMBL
  ENSCAFG00040022026 UniProtKB/TrEMBL
  ENSCAFG00845031046 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000029782.2 UniProtKB/TrEMBL
  ENSCAFT00030021826.1 UniProtKB/TrEMBL
  ENSCAFT00040040882.1 UniProtKB/TrEMBL
  ENSCAFT00845055196 ENTREZGENE
  ENSCAFT00845055196.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/TrEMBL
  GPR119 UniProtKB/TrEMBL
NCBI Gene GPR119 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/TrEMBL
  PTHR22750:SF7 UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A0A8C0JJB9 ENTREZGENE
  A0A8C0THM6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3QZL6 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:41394 ENTREZGENE