NHERF2 (NHERF family PDZ scaffold protein 2)

Gene: NHERF2 (NHERF family PDZ scaffold protein 2) Canis lupus familiaris

Analyze

Symbol:

NHERF2

Name:

NHERF family PDZ scaffold protein 2

RGD ID:

12194536

Description:

ENCODES a protein that exhibits low-density lipoprotein particle receptor binding (ortholog); molecular adaptor activity (ortholog); INVOLVED IN inner ear development (ortholog); negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); phosphatidylinositol 3-kinase/protein kinase B signal transduction (ortholog); PARTICIPATES IN parathyroid hormone signaling pathway; platelet-derived growth factor signaling pathway; ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); hypertension (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog); protein-containing complex (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Na(+)/H(+) exchange regulatory cofactor NHE-RF2; SLC9A3 regulator 2; SLC9A3R2; solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

NCBI Annotation Information:

Annotation category: partial on reference assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	38,905,070 - 38,915,028 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	38,905,635 - 38,942,774 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,144,686 - 40,155,043 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,214,038 - 39,216,647 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,213,735 - 39,216,642 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	38,898,838 - 38,909,179 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	38,871,153 - 38,881,488 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,349,958 - 39,360,323 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

epilepsy (ISO)

genetic disease (ISO)

hypertension (ISO)

idiopathic generalized epilepsy (ISO)

short-rib thoracic dysplasia 9 with or without polydactyly (ISO)

tuberous sclerosis 2 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

inner ear development (ISO)

negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

phosphatidylinositol 3-kinase/protein kinase B signal transduction (ISO)

positive regulation of monoatomic ion transmembrane transport (ISO)

protein localization to plasma membrane (IEA)

sensory perception of sound (ISO)

Cellular Component

apical plasma membrane (IEA)

cytoplasm (ISO)

endomembrane system (IEA)

membrane (IEA)

nucleus (ISO)

plasma membrane (IEA)

protein-containing complex (ISO)

stereocilium (ISO)

stereocilium bundle (ISO)

Molecular Function

beta-catenin binding (IEA)

identical protein binding (IEA)

low-density lipoprotein particle receptor binding (ISO)

molecular adaptor activity (IEA,ISO)

phosphatase binding (IEA)

protein binding (ISO)

protein-membrane adaptor activity (IEA)

signaling receptor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

parathyroid hormone signaling pathway (ISO)

platelet-derived growth factor signaling pathway (ISO)

References

Additional References at PubMed

PMID:20663896	PMID:22301917	PMID:23200831	PMID:30032202

Genomics

Comparative Map Data

NHERF2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	38,905,070 - 38,915,028 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	38,905,635 - 38,942,774 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	40,144,686 - 40,155,043 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	39,214,038 - 39,216,647 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	39,213,735 - 39,216,642 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	38,898,838 - 38,909,179 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	38,871,153 - 38,881,488 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	39,349,958 - 39,360,323 (-)	NCBI		UU_Cfam_GSD_1.0

NHERF2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	2,026,902 - 2,039,026 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	2,025,356 - 2,039,026 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	2,076,903 - 2,089,027 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	2,016,930 - 2,028,484 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	2,016,911 - 2,028,481	NCBI
Celera	16	2,289,067 - 2,301,134 (+)	NCBI		Celera
Cytogenetic Map	16	p13.3	NCBI
HuRef	16	2,001,109 - 2,013,254 (+)	NCBI		HuRef
CHM1_1	16	2,076,850 - 2,089,007 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	2,046,859 - 2,058,835 (+)	NCBI		T2T-CHM13v2.0

Nherf2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	24,858,255 - 24,869,279 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	24,858,260 - 24,869,301 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	24,639,281 - 24,650,305 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	24,639,286 - 24,650,327 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	24,776,227 - 24,787,250 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	24,366,888 - 24,377,878 (-)	NCBI		MGSCv36	mm8
Celera	17	25,161,671 - 25,172,581 (-)	NCBI		Celera
Cytogenetic Map	17	A3.3	NCBI
cM Map	17	12.43	NCBI

Nherf2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	14,167,005 - 14,177,519 (-)	NCBI		GRCr8
mRatBN7.2	10	13,662,461 - 13,672,975 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	13,662,461 - 13,673,049 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	18,409,255 - 18,419,776 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	17,898,101 - 17,908,626 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	13,397,300 - 13,407,821 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	14,003,330 - 14,015,066 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	14,003,320 - 14,013,870 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	13,820,310 - 13,830,824 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	13,890,293 - 13,900,807 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	13,891,061 - 13,900,879 (-)	NCBI
Celera	10	13,342,543 - 13,353,058 (-)	NCBI		Celera
Cytogenetic Map	10	q12	NCBI

Nherf2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	15,224,214 - 15,235,379 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	15,224,214 - 15,235,372 (-)	NCBI	ChiLan1.0	ChiLan1.0

NHERF2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	2,307,556 - 2,319,737 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	6,089,244 - 6,101,377 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	664,310 - 676,640 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	2,121,215 - 2,127,069 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	2,115,583 - 2,127,069 (+)	Ensembl	panpan1.1		panPan2

Nherf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	104,703,346 - 104,707,696 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936694	2,000,854 - 2,006,567 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936694	2,000,977 - 2,006,102 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NHERF2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	39,942,367 - 39,952,825 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	39,942,366 - 39,952,824 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	42,205,136 - 42,239,173 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NHERF2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	1,923,773 - 1,935,641 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	1,924,131 - 1,939,062 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666068	29,129,026 - 29,140,946 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nherf2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624913	210,315 - 221,538 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624913	210,315 - 220,936 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in NHERF2
100 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	5	5	22	6	6	6	6	6	12	8	10	6
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001284463	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_005621714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_022419486	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB679833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000030930 ⟹ ENSCAFP00000028764

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	38,905,938 - 38,915,028 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000043424 ⟹ ENSCAFP00000041636

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	38,905,969 - 38,915,028 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000072439 ⟹ ENSCAFP00000057694

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	38,905,635 - 38,914,935 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000077331 ⟹ ENSCAFP00000061476

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	38,905,938 - 38,929,370 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00000090994 ⟹ ENSCAFP00000046144

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	6	38,905,938 - 38,942,774 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845030141 ⟹ ENSCAFP00845023642

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	6	39,213,735 - 39,216,642 (-)	Ensembl

RefSeq Acc Id:

NM_001284463 ⟹ NP_001271392

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	38,905,938 - 38,915,028 (-)	NCBI
Dog10K_Boxer_Tasha	6	40,144,686 - 40,155,043 (-)	NCBI
ROS_Cfam_1.0	6	39,214,038 - 39,216,647 (-)	NCBI
UMICH_Zoey_3.1	6	38,898,838 - 38,909,179 (-)	NCBI
UNSW_CanFamBas_1.0	6	38,871,153 - 38,881,488 (-)	NCBI
UU_Cfam_GSD_1.0	6	39,349,958 - 39,360,323 (-)	NCBI

Sequence:

show sequence

CAGGTCGTCCGTGCCGCCCCCCACGCCCCGTGCCTGCCCCGCGGGCGTGGGCGCCGTGGCCGGT
CCGCGGTGGGCCGGGGGGCCGCCGGCGCCATGGCAGCCGCGGAGCCGCTGCGGCCGCGCCTGTG
CCGCCTGGTGCGCGGGGAGCACGGCTACGGCTTCCACCTGCACGGCGAGAAGGGCCGCCGCGGC
CAGTTCATCCGGCGCGTGGAGCCCGGCTCGCCGGCCGAGGCGGCTGCGCTGCGCGCGGGGGACC
GGCTGGTCGAGGTCAACGGCGTCAACGTGGAGGGCGAGACGCACCACCAGGTGGTGCAGAGAAT
CAAGGCTGTGGAAGGACAGACTCGGCTGCTGGTGGTGGACAAAGAGACGGACGAGGAGCTCCGC
CGGCGGCAGCTGACCTGCACAGAGGAGATGGCCCAGCGAGGGCTTCCGCCCACCCATGACCCCT
GGGAGCCGAAGCCGGACTGGGCACGTGCAAGCAACCTCAGCTCCGAGGCGGGCCAGAAGGATGT
CGGTGGGCCCCCCAGGGAGCTACGCCCTCGGCTCTGCCACCTGAGAAAGGGCCCCCAAGGTTAC
GGGTTCAACCTGCACAGTGACAAGTCCCGGCCGGGACAGTACATCCGCTCCGTGGACCCAGGCT
CGCCTGCCGCTCACTCTGGCCTCCGCGCCCAGGACAGACTCATCGAGGTGAATGGGCAGAATGT
GGAGGGGCTGCGCCACGCAGAGGTGGTCGCCAGCATCAAGGCGCAGGAGGACGAGGCCCGGCTG
CTGGTGGTGGACCCCGAAACGGATGAGCACTTCAAGCGGCTACGGGTCACACCTACTGAGGAGC
ACGTGGAAGGTCCACTGCTATCACCAGTCACCAATGGGACCAGCCCTGCCCAGCTGAACGGTGG
CTCAGCGTGTTCGTCCCGAAGTGATCTGCCTGGCTTAGACAAGGACACTGAGGACAGCAACACC
TGGAAGCGTGACCCCTTTCAGGAGAGCGGCCTCCACCTGAGCCCCACGGCGGCCGAAGCCAAGG
AGAAGGCGAGAGCCACCCGGGTCAACAAGCGGGCGCCACAGATGGACTGGAACCGGAAGCGCGA
GATCTTCAGCAACTTCTGAGCCCCTCCCTGCCTGTTTGCCGGTGACCCGG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001271392	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAM15277	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000028764.4
	ENSCAFP00000041636.2
	ENSCAFP00000046144.2
	ENSCAFP00000061476.2
	ENSCAFP00030000166.1
	ENSCAFP00030000185.1
	ENSCAFP00030000193.1
	ENSCAFP00030000218.1
	ENSCAFP00040001209.1
	ENSCAFP00040001297.1
	ENSCAFP00040001303.1
	ENSCAFP00845023642
	ENSCAFP00845023642.1

RefSeq Acc Id:

NP_001271392 ⟸ NM_001284463

- UniProtKB:

F1Q039 (UniProtKB/TrEMBL), A0A8C0LNX9 (UniProtKB/TrEMBL), A0A8C0LVM1 (UniProtKB/TrEMBL), I2FJU2 (UniProtKB/TrEMBL), A0A8C0PW39 (UniProtKB/TrEMBL), A0A8P0SNG8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAAEPLRPRLCRLVRGEHGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVNGVNV
EGETHHQVVQRIKAVEGQTRLLVVDKETDEELRRRQLTCTEEMAQRGLPPTHDPWEPKPDWARA
SNLSSEAGQKDVGGPPRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVDPGSPAAHSGLRA
QDRLIEVNGQNVEGLRHAEVVASIKAQEDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLLSPV
TNGTSPAQLNGGSACSSRSDLPGLDKDTEDSNTWKRDPFQESGLHLSPTAAEAKEKARATRVNK
RAPQMDWNRKREIFSNF

hide sequence

RefSeq Acc Id:

ENSCAFP00000028764 ⟸ ENSCAFT00000030930

RefSeq Acc Id:

ENSCAFP00000061476 ⟸ ENSCAFT00000077331

RefSeq Acc Id:

ENSCAFP00000057694 ⟸ ENSCAFT00000072439

RefSeq Acc Id:

ENSCAFP00000041636 ⟸ ENSCAFT00000043424

RefSeq Acc Id:

ENSCAFP00000046144 ⟸ ENSCAFT00000090994

RefSeq Acc Id:

ENSCAFP00845023642 ⟸ ENSCAFT00845030141

Protein Domains

PDZ

Promoters

RGD ID:

13683735

Promoter ID:

EPDNEW_C1803

Type:

single initiation site

Name:

SLC9A3R2_1

Description:

SLC9A3 regulator 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	6	38,914,952 - 38,915,012	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000019449	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030000138	UniProtKB/TrEMBL
	ENSCAFG00040000769	UniProtKB/TrEMBL
	ENSCAFG00845017011	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000030930.6	UniProtKB/TrEMBL
	ENSCAFT00000043424.3	UniProtKB/TrEMBL
	ENSCAFT00000077331.2	UniProtKB/TrEMBL
	ENSCAFT00000090994.2	UniProtKB/TrEMBL
	ENSCAFT00030000198.1	UniProtKB/TrEMBL
	ENSCAFT00030000218.1	UniProtKB/TrEMBL
	ENSCAFT00030000226.1	UniProtKB/TrEMBL
	ENSCAFT00030000251.1	UniProtKB/TrEMBL
	ENSCAFT00040001417.1	UniProtKB/TrEMBL
	ENSCAFT00040001523.1	UniProtKB/TrEMBL
	ENSCAFT00040001533.1	UniProtKB/TrEMBL
	ENSCAFT00845030141	ENTREZGENE
	ENSCAFT00845030141.1	UniProtKB/TrEMBL
Gene3D-CATH	2.30.42.10	UniProtKB/TrEMBL
InterPro	EBP50_C-term	UniProtKB/TrEMBL
	NHERF-1/NHERF-2	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
	PDZ_sf	UniProtKB/TrEMBL
KEGG Report	cfa:479884	UniProtKB/TrEMBL
NCBI Gene	SLC9A3R2	ENTREZGENE
PANTHER	PDZ DOMAIN CONTAINING PROTEIN	UniProtKB/TrEMBL
	PTHR14191:SF4	UniProtKB/TrEMBL
Pfam	EBP50_C	UniProtKB/TrEMBL
	PDZ	UniProtKB/TrEMBL
PIRSF	EBP50	UniProtKB/TrEMBL
PROSITE	PDZ	UniProtKB/TrEMBL
SMART	PDZ	UniProtKB/TrEMBL
Superfamily-SCOP	SSF50156	UniProtKB/TrEMBL
UniProt	A0A8C0LNX9	ENTREZGENE
	A0A8C0LR33_CANLF	UniProtKB/TrEMBL
	A0A8C0LVM1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0PW39	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0RUZ4_CANLF	UniProtKB/TrEMBL
	A0A8I3P349_CANLF	UniProtKB/TrEMBL
	A0A8P0SNG8	ENTREZGENE
	A0A8P0SVJ4_CANLF	UniProtKB/TrEMBL
	A0A8P0SZ56_CANLF	UniProtKB/TrEMBL
	F1Q039	ENTREZGENE, UniProtKB/TrEMBL
	I2FJU2	ENTREZGENE
UniProt Secondary	A0A8P0PAB3	UniProtKB/TrEMBL
	A0A8P0SNG8	UniProtKB/TrEMBL
	I2FJU2	UniProtKB/TrEMBL
VGNC ID	VGNC:46486	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-12-12	NHERF2	NHERF family PDZ scaffold protein 2	SLC9A3R2	SLC9A3 regulator 2	Symbol and/or name change	19259463	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)