AURKA (aurora kinase A) - Rat Genome Database

Name: AURKA
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: AURKA (aurora kinase A) Canis lupus familiaris

Analyze

Symbol:

AURKA

Name:

aurora kinase A

RGD ID:

12184828

Description:

ENCODES a protein that exhibits histone H3S10 kinase activity (ortholog); molecular function activator activity (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN positive regulation of mitotic cell cycle; anterior/posterior axis specification (ortholog); apoptotic process (ortholog); ASSOCIATED WITH Aneuploidy (ortholog); Breast Neoplasms (ortholog); Chromosomal Instability (ortholog); FOUND IN basolateral plasma membrane; spindle pole; axon hillock (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

serine/threonine-protein kinase 6

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AURKA (aurora kinase A)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Aurka (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Aurka (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Aurka (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AURKA (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Aurka (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	AURKA (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	AURKA (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Aurka (aurora kinase A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	41,585,483 - 41,604,875 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	41,585,518 - 41,604,791 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	40,833,209 - 40,852,906 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	42,296,241 - 42,316,154 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	42,296,229 - 42,315,779 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	41,536,239 - 41,555,929 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	41,675,064 - 41,694,968 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	42,333,178 - 42,352,923 (-)	NCBI		UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aneuploidy (ISO)

Breast Neoplasms (ISO)

Chromosomal Instability (ISO)

Chronic Hepatitis C (ISO)

colon cancer (ISO)

colorectal cancer (ISO)

Colorectal Neoplasms (ISO)

COVID-19 (ISO)

endometrial carcinoma (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

invasive ductal carcinoma (ISO)

Kidney Neoplasms (ISO)

melanoma (ISO)

multiple myeloma (ISO)

neuroblastoma (ISO)

ovarian cancer (ISO)

ovary epithelial cancer (ISO)

peripheral nervous system disease (ISO)

prostate carcinoma in situ (ISO)

Prostatic Neoplasms (ISO)

renal cell carcinoma (ISO)

urinary bladder cancer (ISO)

Urologic Neoplasms (ISO)

uterine cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior/posterior axis specification (ISO)

apoptotic process (ISO)

cell division (IEA)

centrosome cycle (IEA,ISO)

centrosome localization (ISO)

cilium disassembly (ISO)

liver regeneration (ISO)

meiotic cell cycle (IEA,ISO)

meiotic spindle organization (IEA,ISO)

microtubule cytoskeleton organization (ISO)

mitotic cell cycle (IEA,ISO)

mitotic centrosome separation (IEA,ISO)

mitotic spindle organization (IEA,ISO)

negative regulation of apoptotic process (ISO)

negative regulation of gene expression (ISO)

neuron projection extension (ISO)

positive regulation of meiotic cell cycle process involved in oocyte maturation (ISO)

positive regulation of mitochondrial fission (ISO)

positive regulation of mitotic cell cycle (IMP)

positive regulation of oocyte maturation (ISO)

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (ISO)

positive regulation of translation (ISO)

proteasome-mediated ubiquitin-dependent protein catabolic process (ISO)

protein localization to centrosome (ISO)

protein phosphorylation (ISO)

regulation of cytokinesis (IEA)

regulation of protein stability (ISO)

response to estradiol (ISO)

response to wounding (ISO)

spindle assembly involved in female meiosis I (ISO)

spindle organization (ISO)

Cellular Component

axon hillock (ISO)

basolateral plasma membrane (IDA,IEA)

cell projection (IEA)

centriole (IEA)

centrosome (IEA,ISO)

chromosome passenger complex (IEA)

ciliary basal body (ISO)

cilium (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

cytosol (ISO)

germinal vesicle (ISO)

glutamatergic synapse (ISO)

kinetochore (IEA)

meiotic spindle (ISO)

microtubule (IEA)

microtubule cytoskeleton (ISO)

microtubule organizing center (ISO)

mitotic spindle (ISO)

mitotic spindle pole (ISO)

neuron projection (IEA)

nucleoplasm (ISO)

nucleus (ISO)

perinuclear region of cytoplasm (ISO)

plasma membrane (IEA)

postsynaptic density (ISO)

pronucleus (ISO)

spindle microtubule (IEA)

spindle midzone (IEA)

spindle pole (IDA,IEA)

spindle pole centrosome (IEA)

Molecular Function

ATP binding (IEA)

histone H3S10 kinase activity (ISO)

molecular function activator activity (ISO)

protein binding (ISO)

protein heterodimerization activity (ISO)

protein kinase activity (IEA)

protein kinase binding (ISO)

protein serine/threonine kinase activity (IEA,ISO)

ubiquitin protein ligase binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202	PMID:37756605

Genomics

Comparative Map Data

AURKA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	41,585,483 - 41,604,875 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	41,585,518 - 41,604,791 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	40,833,209 - 40,852,906 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	42,296,241 - 42,316,154 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	42,296,229 - 42,315,779 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	41,536,239 - 41,555,929 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	41,675,064 - 41,694,968 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	42,333,178 - 42,352,923 (-)	NCBI		UU_Cfam_GSD_1.0

AURKA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	56,369,390 - 56,392,215 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	56,369,389 - 56,392,337 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	54,944,446 - 54,967,271 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	54,377,852 - 54,400,758 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	20	51,683,792 - 51,707,784 (-)	NCBI		Celera
Cytogenetic Map	20	q13.2	NCBI
HuRef	20	51,729,262 - 51,752,229 (-)	NCBI		HuRef
CHM1_1	20	54,845,539 - 54,868,444 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	20	58,146,836 - 58,169,709 (-)	NCBI		T2T-CHM13v2.0

Aurka
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	172,198,116 - 172,212,825 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	172,198,110 - 172,212,455 (-)	Ensembl		GRCm39 Ensembl
GRCm38	2	172,356,190 - 172,370,886 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	172,356,190 - 172,370,535 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	172,181,696 - 172,196,006 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	172,047,401 - 172,061,711 (-)	NCBI		MGSCv36	mm8
Celera	2	178,315,373 - 178,329,688 (-)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	94.84	NCBI

Aurka
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	181,546,742 - 181,562,890 (-)	NCBI		GRCr8
mRatBN7.2	3	161,128,309 - 161,144,524 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,128,313 - 161,144,390 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	164,937,768 - 164,951,932 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	173,436,787 - 173,450,951 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,178,603 - 171,192,767 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	170,364,177 - 170,380,278 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	170,364,181 - 170,378,210 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	176,437,310 - 176,456,036 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	163,270,479 - 163,284,506 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	163,177,671 - 163,190,537 (-)	NCBI
Celera	3	160,328,562 - 160,342,589 (-)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

Aurka
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	2,831,157 - 2,853,357 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	2,831,073 - 2,853,151 (+)	NCBI	ChiLan1.0	ChiLan1.0

AURKA
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	62,116,577 - 62,139,405 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	62,109,695 - 62,132,523 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	52,707,757 - 52,730,579 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	53,994,880 - 54,017,381 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	53,994,881 - 54,017,339 (-)	Ensembl	panpan1.1		panPan2

Aurka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	183,775,540 - 183,790,540 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936875	295,238 - 310,457 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AURKA
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	17	56,954,838 - 56,972,435 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	64,066,378 - 64,083,673 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AURKA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	7,730,060 - 7,753,167 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	7,734,128 - 7,752,395 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666050	55,804,778 - 55,827,848 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Aurka
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	147,149 - 161,344 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624790	143,818 - 162,065 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in AURKA
274 total Variants

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	adipose tissue
High
Medium	2									8
Low	3	4	22	6	6	6	6	3	12		10	6
Below cutoff		1						3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005635197	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434136	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434137	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038434138	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038457672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038457673	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038509303	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038509304	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038509305	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572642	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572643	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038572644	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636915	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038636917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000376	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCAFT00000043303 ⟹ ENSCAFP00000038502

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	24	41,585,518 - 41,604,791 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845051692 ⟹ ENSCAFP00845040557

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	42,296,229 - 42,315,779 (-)	Ensembl

RefSeq Acc Id:

ENSCAFT00845051705 ⟹ ENSCAFP00845040568

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	24	42,296,276 - 42,315,779 (-)	Ensembl

RefSeq Acc Id:

XM_005635197 ⟹ XP_005635254

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	24	41,585,483 - 41,604,875 (-)	NCBI
Dog10K_Boxer_Tasha	24	40,833,209 - 40,852,906 (-)	NCBI

Sequence:

show sequence

AGGCAGCACCTCTCGAGCTCCGGCCAATCAGCTTCCAGAGCAGAGGGTTTAACTCTTGTTTAAA
ATGAAGACTTTGAATCTTAACGGCTGAGCGCTCCGGGGGACTCGGCGGCTTGGGTCGGAGGCTG
GAGCCGGCGGGCATTATGGACAAATCTAAAGAAAACTGCATTGCAGGGCCTGTTAAGACTGCAA
TTGCACTTGGTGATGGTCCAAAACGTGTTCTGGTGACTCAGCAAGTTCCTTCACAGAATCCATT
ATCTGCAAATAGTGGCCAGGCCCAGCGGGTCTTGTGTCCTTCAAATTCTTCCCAGCGAGTTCCT
CCACAAACCCAAAAGCTCGTCTCCAGCCATAAACCGGCTCAGAATCTGAAGCAGAAGCAATTGC
AGGCAACTGGTGTCCCTCGTCCTGCCTCTAGGTCACTGAATAATACCCAAAAGAGTGAGCAACC
CTCGTCATCAGCCCCTGGAAATAATTCTGAAAAGGAACTGGCAACAAAACAGAAAAATGAAGAA
TCAAAAAAAAGGCAATGGGCTTTGGAAGATTTTGAAATTGGTCGCCCACTGGGTAAAGGAAAGT
TTGGTAATGTTTACTTGGCAAGGGAAAAACAAAGCAAGTTTATCCTGGCTATTAAAGTATTATT
TAAAGCTCAACTGGAGAAAGCAGGAGTTGAACATCAGCTGAGAAGAGAAGTAGAAATACAGTCC
CACCTTAGGCATCCAAATATTCTTAGGCTGTATGGTTATTTCCATGATGCCACCAGAGTTTACC
TAATTCTAGAATATGCACCTCTTGGAGCTGTCTACAGAGAACTTCAGAAACTGTCAAAGTTTGA
TGAGCAGAGAACTGCTACTTATATCACAGAGTTGGCAGATGCCCTGTCTTACTGTCACTCAAAG
AGAGTCATTCACAGAGACATTAAGCCAGAGAACCTACTCCTTGGATCAGCTGGAGAGCTTAAGA
TTGCAGATTTTGGGTGGTCAGTACATGCTCCATCCTCCAGGAGAACCACCCTGTGTGGCACCCT
GGATTACTTGCCCCCAGAGATGATTGAAGGCCGAATGCATGATGAGAAGGTGGATCTCTGGAGC
CTTGGGGTTCTTTGCTATGAATTTCTAGTTGGGAAGCCTCCTTTTGAGGCAAGCACATACCAAG
AGACCTACAAAAGAATATCACGGGTTGAATTCACATTCCCTGACTTCGTGCCGGAGGGAGCCAG
GGATCTCATTTCAAGACTGTTGAAACATAATCCCAGCCAAAGGCCAACTCTCAAGGATGTACTT
GAACACCCGTGGATCATGGCTAACTCATCAAAACCATCAAGTAGCCAAAAAAACAAAGACTCAA
CTAGCAAACAGTCTTAAGGATTGTGCAGGAGGAGAAATCTGAGAGGCAGAGCTGCTGCTGATAC
TGCTGACGGCCTGCCCGTGACGGAGGACGCTGCAGACAAAGGCCTACTGCGCCAGGTGGCGCCT
CGGCCTCCCCACTTGAGTCTACTTAAGTGAACAGTACGCTCTGGAGTGAAAGTAGCCACAGGAA
TTGTGGCAGTGTCACTAGTTTCACAATTTGGAGGTGAGGTTCACCTGGACCTCCCCACAGCCTG
TTTCGAGTCAGGCTTCCTTGTGGAAGACCCACTCCAGGTCCTACTGCAGGGAGAGTGGCCACCT
CGCCATGACTCCATCAGTGAAAGAGGCGTGCAATAACCTTCCAAGTACCTACGTGTGTGTGTAA
CTTATTGGGTGGCCAAATCTGGTAAAGCTGTCAGGATGAACATGTGATTCTTTCTTTTAAATGT
TAAAATAAAGATTTTTATAAAGACTTC

hide sequence

RefSeq Acc Id:

XM_038434136 ⟹ XP_038290064

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	42,296,241 - 42,312,659 (-)	NCBI

RefSeq Acc Id:

XM_038434137 ⟹ XP_038290065

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	42,296,241 - 42,316,154 (-)	NCBI

RefSeq Acc Id:

XM_038434138 ⟹ XP_038290066

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	24	42,296,241 - 42,313,802 (-)	NCBI

RefSeq Acc Id:

XM_038457672 ⟹ XP_038313600

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	24	40,833,209 - 40,849,412 (-)	NCBI

RefSeq Acc Id:

XM_038457673 ⟹ XP_038313601

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	24	40,833,209 - 40,850,555 (-)	NCBI

RefSeq Acc Id:

XM_038509303 ⟹ XP_038365231

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	41,536,239 - 41,552,437 (-)	NCBI

RefSeq Acc Id:

XM_038509304 ⟹ XP_038365232

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	41,536,239 - 41,555,929 (-)	NCBI

RefSeq Acc Id:

XM_038509305 ⟹ XP_038365233

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	24	41,536,239 - 41,553,580 (-)	NCBI

RefSeq Acc Id:

XM_038572642 ⟹ XP_038428570

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	42,333,178 - 42,349,404 (-)	NCBI

RefSeq Acc Id:

XM_038572643 ⟹ XP_038428571

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	42,333,178 - 42,352,923 (-)	NCBI

RefSeq Acc Id:

XM_038572644 ⟹ XP_038428572

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	24	42,333,178 - 42,350,547 (-)	NCBI

RefSeq Acc Id:

XM_038636915 ⟹ XP_038492843

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	41,675,064 - 41,691,477 (-)	NCBI

RefSeq Acc Id:

XM_038636916 ⟹ XP_038492844

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	41,675,064 - 41,694,968 (-)	NCBI

RefSeq Acc Id:

XM_038636917 ⟹ XP_038492845

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	24	41,675,064 - 41,692,620 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_005635254	(Get FASTA)	NCBI Sequence Viewer
	XP_038290064	(Get FASTA)	NCBI Sequence Viewer
	XP_038290065	(Get FASTA)	NCBI Sequence Viewer
	XP_038290066	(Get FASTA)	NCBI Sequence Viewer
	XP_038313600	(Get FASTA)	NCBI Sequence Viewer
	XP_038313601	(Get FASTA)	NCBI Sequence Viewer
	XP_038365231	(Get FASTA)	NCBI Sequence Viewer
	XP_038365232	(Get FASTA)	NCBI Sequence Viewer
	XP_038365233	(Get FASTA)	NCBI Sequence Viewer
	XP_038428570	(Get FASTA)	NCBI Sequence Viewer
	XP_038428571	(Get FASTA)	NCBI Sequence Viewer
	XP_038428572	(Get FASTA)	NCBI Sequence Viewer
	XP_038492843	(Get FASTA)	NCBI Sequence Viewer
	XP_038492844	(Get FASTA)	NCBI Sequence Viewer
	XP_038492845	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000038502.2
	ENSCAFP00000069416.1
	ENSCAFP00030040741.1
	ENSCAFP00040022576.1
	ENSCAFP00845040557.1
	ENSCAFP00845040568
	ENSCAFP00845040568.1

RefSeq Acc Id:	XP_005635254 ⟸ XM_005635197
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL), A0A8P0NQ50 (UniProtKB/TrEMBL), A0A9E9U9L2 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDKSKENCIAGPVKTAIALGDGPKRVLVTQQVPSQNPLSANSGQAQRVLCPSNSSQRVPPQTQK LVSSHKPAQNLKQKQLQATGVPRPASRSLNNTQKSEQPSSSAPGNNSEKELATKQKNEESKKRQ WALEDFEIGRPLGKGKFGNVYLAREKQSKFILAIKVLFKAQLEKAGVEHQLRREVEIQSHLRHP NILRLYGYFHDATRVYLILEYAPLGAVYRELQKLSKFDEQRTATYITELADALSYCHSKRVIHR DIKPENLLLGSAGELKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLC YEFLVGKPPFEASTYQETYKRISRVEFTFPDFVPEGARDLISRLLKHNPSQRPTLKDVLEHPWI MANSSKPSSSQKNKDSTSKQS hide sequence

RefSeq Acc Id:

ENSCAFP00000038502 ⟸ ENSCAFT00000043303

RefSeq Acc Id:	XP_038365232 ⟸ XM_038509304
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038365233 ⟸ XM_038509305
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038365231 ⟸ XM_038509303
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038492844 ⟸ XM_038636916
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038492845 ⟸ XM_038636917
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038492843 ⟸ XM_038636915
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038290065 ⟸ XM_038434137
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S724 (UniProtKB/Swiss-Prot), A0A8C0YY51 (UniProtKB/Swiss-Prot), A0A8C0RTC6 (UniProtKB/Swiss-Prot), A0A8I3Q7K5 (UniProtKB/Swiss-Prot), A0A8C0LBG7 (UniProtKB/TrEMBL), A0A8C0LS72 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038290066 ⟸ XM_038434138
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I3S724 (UniProtKB/Swiss-Prot), A0A8C0YY51 (UniProtKB/Swiss-Prot), A0A8C0RTC6 (UniProtKB/Swiss-Prot), A0A8I3Q7K5 (UniProtKB/Swiss-Prot), A0A8C0LBG7 (UniProtKB/TrEMBL), A0A8C0LS72 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038290064 ⟸ XM_038434136
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038313601 ⟸ XM_038457673
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL), A0A8P0NQ50 (UniProtKB/TrEMBL), A0A9E9U9L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038313600 ⟸ XM_038457672
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428571 ⟸ XM_038572643
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428572 ⟸ XM_038572644
- Peptide Label:	isoform X4
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038428570 ⟸ XM_038572642
- Peptide Label:	isoform X3
- UniProtKB:	A0A8C0LBG7 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSCAFP00845040568 ⟸ ENSCAFT00845051705

RefSeq Acc Id:

ENSCAFP00845040557 ⟸ ENSCAFT00845051692

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000029331	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030025248	UniProtKB/Swiss-Prot
	ENSCAFG00040014049	UniProtKB/TrEMBL
	ENSCAFG00845029207	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000043303.3	UniProtKB/TrEMBL
	ENSCAFT00000102078.1	UniProtKB/TrEMBL
	ENSCAFT00030046613.1	UniProtKB/Swiss-Prot
	ENSCAFT00040025952.1	UniProtKB/TrEMBL
	ENSCAFT00845051692.1	UniProtKB/TrEMBL
	ENSCAFT00845051705	ENTREZGENE
	ENSCAFT00845051705.1	UniProtKB/Swiss-Prot
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Aur	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	AURKA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	cfa:485940	UniProtKB/TrEMBL
NCBI Gene	AURKA	ENTREZGENE
PANTHER	AURORA KINASE A	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR24350	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Protein kinase-like (PK-like)	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt	A0A8C0LBG7	ENTREZGENE
	A0A8C0LS72	ENTREZGENE
	A0A8C0RTC6	ENTREZGENE
	A0A8C0YY51	ENTREZGENE
	A0A8I3Q7K5	ENTREZGENE
	A0A8I3S724	ENTREZGENE
	A0A8P0NQ50	ENTREZGENE, UniProtKB/TrEMBL
	A0A9E9U9L2	ENTREZGENE
	A0A9G0SAW5_CANLF	UniProtKB/TrEMBL
	A0A9J7R993_CANLF	UniProtKB/TrEMBL
	AURKA_CANLF	UniProtKB/Swiss-Prot
UniProt Secondary	A0A8C0RTC6	UniProtKB/Swiss-Prot
	A0A8C0YY51	UniProtKB/Swiss-Prot
	A0A8I3Q7K5	UniProtKB/Swiss-Prot
	A0A9E9U9L2	UniProtKB/TrEMBL
VGNC ID	VGNC:38311	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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