PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) - Rat Genome Database

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Gene: PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) Canis lupus familiaris
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Symbol: PIK3C2A
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha
RGD ID: 12180572
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (inferred); 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (inferred); 1-phosphatidylinositol-4-phosphate 3-kinase activity (inferred); INVOLVED IN autophagosome organization (ortholog); cellular response to starvation (ortholog); macroautophagy (ortholog); PARTICIPATES IN phosphoinositide metabolic pathway; ASSOCIATED WITH Dwarfism (ortholog); genetic disease (ortholog); intellectual disability (ortholog); FOUND IN clathrin-coated vesicle (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC102154709; phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; phosphoinositide-3-kinase, class 2, alpha polypeptide; uncharacterized LOC102154709
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12139,693,211 - 39,868,603 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2139,695,520 - 39,784,639 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2139,193,753 - 39,309,848 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02140,798,394 - 40,914,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2140,799,161 - 40,914,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12139,813,119 - 39,927,798 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02140,018,167 - 40,133,971 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02140,357,482 - 40,473,688 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PIK3C2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12139,693,211 - 39,868,603 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2139,695,520 - 39,784,639 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2139,193,753 - 39,309,848 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02140,798,394 - 40,914,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2140,799,161 - 40,914,780 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12139,813,119 - 39,927,798 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02140,018,167 - 40,133,971 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02140,357,482 - 40,473,688 (-)NCBIUU_Cfam_GSD_1.0
PIK3C2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381117,086,575 - 17,207,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1117,077,730 - 17,207,986 (-)EnsemblGRCh38hg38GRCh38
GRCh371117,108,122 - 17,229,533 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,064,698 - 17,147,930 (-)NCBINCBI36Build 36hg18NCBI36
Build 341117,067,860 - 17,147,864NCBI
Celera1117,236,314 - 17,320,701 (-)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1116,791,536 - 16,875,065 (-)NCBIHuRef
CHM1_11117,107,728 - 17,190,971 (-)NCBICHM1_1
T2T-CHM13v2.01117,184,463 - 17,305,651 (-)NCBIT2T-CHM13v2.0
Pik3c2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397115,936,500 - 116,042,693 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7115,936,500 - 116,042,684 (-)EnsemblGRCm39 Ensembl
GRCm387116,337,265 - 116,443,465 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7116,337,265 - 116,443,449 (-)EnsemblGRCm38mm10GRCm38
MGSCv377123,480,790 - 123,586,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367116,130,710 - 116,209,201 (-)NCBIMGSCv36mm8
Celera7116,275,791 - 116,376,830 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map761.62NCBI
Pik3c2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81180,012,248 - 180,117,786 (-)NCBIGRCr8
mRatBN7.21170,577,942 - 170,684,353 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1170,577,942 - 170,683,472 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1178,895,808 - 179,001,695 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01186,082,327 - 186,188,218 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01178,795,249 - 178,900,740 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01185,210,922 - 185,326,314 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,210,922 - 185,326,314 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,182,647 - 192,297,034 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,430,831 - 174,537,706 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11174,572,538 - 174,676,951 (-)NCBI
Celera1168,399,225 - 168,504,593 (-)NCBICelera
Cytogenetic Map1q35NCBI
Pik3c2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541431,896,161 - 31,999,730 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541431,896,161 - 31,999,730 (-)NCBIChiLan1.0ChiLan1.0
PIK3C2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2919,421,635 - 19,542,611 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11119,382,544 - 19,503,423 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01117,143,024 - 17,263,920 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11116,828,959 - 16,949,891 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1116,828,966 - 16,949,856 (-)Ensemblpanpan1.1panPan2
Pik3c2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494745,811,389 - 45,932,425 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365281,869,527 - 1,964,183 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365281,845,372 - 1,964,908 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3C2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl241,829,916 - 42,024,362 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1241,829,969 - 42,024,062 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2244,958,962 - 45,079,401 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3C2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1147,759,850 - 47,874,458 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl147,795,954 - 47,877,028 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038145,200,659 - 145,318,077 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3c2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247668,701,642 - 8,776,578 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247668,698,836 - 8,834,928 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PIK3C2A
1625 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 13 3 8 7 9 2
Low 5 5 9 6 3 6 6 6 4 1 1 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005633716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407894 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022407895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038430623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038456240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038505949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038569168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038569169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038569170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038569171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038633361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_542517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000046875   ⟹   ENSCAFP00000036143
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2139,696,135 - 39,784,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000049408   ⟹   ENSCAFP00000039705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2139,695,520 - 39,784,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000061398   ⟹   ENSCAFP00000060708
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2139,696,135 - 39,784,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000070168   ⟹   ENSCAFP00000047737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2139,696,135 - 39,784,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000080372   ⟹   ENSCAFP00000060779
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2139,696,135 - 39,784,639 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845047820   ⟹   ENSCAFP00845037520
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2140,799,161 - 40,914,780 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845047986   ⟹   ENSCAFP00845037650
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2140,799,161 - 40,914,780 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845048172   ⟹   ENSCAFP00845037785
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2140,800,787 - 40,914,780 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845048375   ⟹   ENSCAFP00845037953
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2140,800,787 - 40,914,780 (-)Ensembl
RefSeq Acc Id: XM_005633716   ⟹   XP_005633773
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12139,693,211 - 39,808,309 (-)NCBI
Dog10K_Boxer_Tasha2139,193,753 - 39,308,671 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022407895   ⟹   XP_022263603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12139,693,211 - 39,809,519 (-)NCBI
Dog10K_Boxer_Tasha2139,193,753 - 39,309,816 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038430620   ⟹   XP_038286548
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02140,798,394 - 40,914,802 (-)NCBI
RefSeq Acc Id: XM_038430621   ⟹   XP_038286549
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02140,798,394 - 40,913,629 (-)NCBI
RefSeq Acc Id: XM_038430622   ⟹   XP_038286550
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02140,798,394 - 40,914,770 (-)NCBI
RefSeq Acc Id: XM_038430623   ⟹   XP_038286551
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02140,798,394 - 40,914,802 (-)NCBI
RefSeq Acc Id: XM_038456240   ⟹   XP_038312168
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2139,193,753 - 39,309,848 (-)NCBI
RefSeq Acc Id: XM_038505946   ⟹   XP_038361874
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12139,813,119 - 39,927,798 (-)NCBI
RefSeq Acc Id: XM_038505947   ⟹   XP_038361875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12139,813,119 - 39,926,623 (-)NCBI
RefSeq Acc Id: XM_038505948   ⟹   XP_038361876
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12139,813,119 - 39,927,767 (-)NCBI
RefSeq Acc Id: XM_038505949   ⟹   XP_038361877
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12139,813,119 - 39,927,798 (-)NCBI
RefSeq Acc Id: XM_038569168   ⟹   XP_038425096
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02140,357,482 - 40,473,688 (-)NCBI
RefSeq Acc Id: XM_038569169   ⟹   XP_038425097
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02140,357,482 - 40,472,515 (-)NCBI
RefSeq Acc Id: XM_038569170   ⟹   XP_038425098
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02140,357,482 - 40,473,656 (-)NCBI
RefSeq Acc Id: XM_038569171   ⟹   XP_038425099
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02140,357,482 - 40,473,688 (-)NCBI
RefSeq Acc Id: XM_038633357   ⟹   XP_038489285
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02140,018,167 - 40,133,971 (-)NCBI
RefSeq Acc Id: XM_038633359   ⟹   XP_038489287
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02140,018,167 - 40,132,829 (-)NCBI
RefSeq Acc Id: XM_038633360   ⟹   XP_038489288
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02140,018,167 - 40,133,940 (-)NCBI
RefSeq Acc Id: XM_038633361   ⟹   XP_038489289
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02140,018,167 - 40,133,971 (-)NCBI
RefSeq Acc Id: XM_542517   ⟹   XP_542517
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12139,693,211 - 39,809,529 (-)NCBI
Dog10K_Boxer_Tasha2139,193,753 - 39,309,848 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005633773 (Get FASTA)   NCBI Sequence Viewer  
  XP_022263603 (Get FASTA)   NCBI Sequence Viewer  
  XP_038286548 (Get FASTA)   NCBI Sequence Viewer  
  XP_038286549 (Get FASTA)   NCBI Sequence Viewer  
  XP_038286550 (Get FASTA)   NCBI Sequence Viewer  
  XP_038286551 (Get FASTA)   NCBI Sequence Viewer  
  XP_038312168 (Get FASTA)   NCBI Sequence Viewer  
  XP_038361874 (Get FASTA)   NCBI Sequence Viewer  
  XP_038361875 (Get FASTA)   NCBI Sequence Viewer  
  XP_038361876 (Get FASTA)   NCBI Sequence Viewer  
  XP_038361877 (Get FASTA)   NCBI Sequence Viewer  
  XP_038425096 (Get FASTA)   NCBI Sequence Viewer  
  XP_038425097 (Get FASTA)   NCBI Sequence Viewer  
  XP_038425098 (Get FASTA)   NCBI Sequence Viewer  
  XP_038425099 (Get FASTA)   NCBI Sequence Viewer  
  XP_038489285 (Get FASTA)   NCBI Sequence Viewer  
  XP_038489287 (Get FASTA)   NCBI Sequence Viewer  
  XP_038489288 (Get FASTA)   NCBI Sequence Viewer  
  XP_038489289 (Get FASTA)   NCBI Sequence Viewer  
  XP_542517 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000036143.2
  ENSCAFP00000039705.2
  ENSCAFP00000060708.1
  ENSCAFP00000060779.2
  ENSCAFP00030040244.1
  ENSCAFP00030040302.1
  ENSCAFP00040034814.1
  ENSCAFP00040035009.1
  ENSCAFP00040035086.1
  ENSCAFP00040035301.1
  ENSCAFP00845037520
  ENSCAFP00845037520.1
  ENSCAFP00845037650
  ENSCAFP00845037650.1
  ENSCAFP00845037785.1
  ENSCAFP00845037953.1
RefSeq Acc Id: XP_542517   ⟸   XM_542517
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005633773   ⟸   XM_005633716
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022263603   ⟸   XM_022407895
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000039705   ⟸   ENSCAFT00000049408
RefSeq Acc Id: ENSCAFP00000047737   ⟸   ENSCAFT00000070168
RefSeq Acc Id: ENSCAFP00000060779   ⟸   ENSCAFT00000080372
RefSeq Acc Id: ENSCAFP00000060708   ⟸   ENSCAFT00000061398
RefSeq Acc Id: ENSCAFP00000036143   ⟸   ENSCAFT00000046875
RefSeq Acc Id: XP_038361877   ⟸   XM_038505949
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038361874   ⟸   XM_038505946
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038361876   ⟸   XM_038505948
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038361875   ⟸   XM_038505947
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038489289   ⟸   XM_038633361
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038489285   ⟸   XM_038633357
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038489288   ⟸   XM_038633360
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038489287   ⟸   XM_038633359
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038286551   ⟸   XM_038430623
- Peptide Label: isoform X2
- UniProtKB: A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286548   ⟸   XM_038430620
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286550   ⟸   XM_038430622
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038286549   ⟸   XM_038430621
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038312168   ⟸   XM_038456240
- Peptide Label: isoform X2
- UniProtKB: A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038425099   ⟸   XM_038569171
- Peptide Label: isoform X2
- UniProtKB: A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038425096   ⟸   XM_038569168
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038425098   ⟸   XM_038569170
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038425097   ⟸   XM_038569169
- Peptide Label: isoform X1
- UniProtKB: A0A8C0RT86 (UniProtKB/TrEMBL),   A0A8I3S670 (UniProtKB/TrEMBL),   A0A8I3SAR3 (UniProtKB/TrEMBL),   A0A8P0NR49 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845037650   ⟸   ENSCAFT00845047986
RefSeq Acc Id: ENSCAFP00845037785   ⟸   ENSCAFT00845048172
RefSeq Acc Id: ENSCAFP00845037520   ⟸   ENSCAFT00845047820
RefSeq Acc Id: ENSCAFP00845037953   ⟸   ENSCAFT00845048375
Protein Domains
C2   C2 PI3K-type   PI3K-RBD   PI3K/PI4K catalytic   PIK helical   PX


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000031546 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030024975 UniProtKB/TrEMBL
  ENSCAFG00040021474 UniProtKB/TrEMBL
  ENSCAFG00845027085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000046875.3 UniProtKB/TrEMBL
  ENSCAFT00000049408.4 UniProtKB/TrEMBL
  ENSCAFT00000061398.2 UniProtKB/TrEMBL
  ENSCAFT00000080372.2 UniProtKB/TrEMBL
  ENSCAFT00030046069.1 UniProtKB/TrEMBL
  ENSCAFT00030046134.1 UniProtKB/TrEMBL
  ENSCAFT00040039891.1 UniProtKB/TrEMBL
  ENSCAFT00040040113.1 UniProtKB/TrEMBL
  ENSCAFT00040040203.1 UniProtKB/TrEMBL
  ENSCAFT00040040468.1 UniProtKB/TrEMBL
  ENSCAFT00845047820 ENTREZGENE
  ENSCAFT00845047820.1 UniProtKB/TrEMBL
  ENSCAFT00845047986 ENTREZGENE
  ENSCAFT00845047986.1 UniProtKB/TrEMBL
  ENSCAFT00845048172.1 UniProtKB/TrEMBL
  ENSCAFT00845048375.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1070.11 UniProtKB/TrEMBL
  1.25.40.70 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.30.1520.10 UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  PI3/4_kinase_cat_dom UniProtKB/TrEMBL
  PI3/4_kinase_cat_sf UniProtKB/TrEMBL
  PI3/4_kinase_CS UniProtKB/TrEMBL
  PI3K-C2-alpha_dom UniProtKB/TrEMBL
  PI3K-type_C2_dom UniProtKB/TrEMBL
  PI3K_accessory_dom UniProtKB/TrEMBL
  PI3K_accessory_sf UniProtKB/TrEMBL
  PI3K_Ras-bd_dom UniProtKB/TrEMBL
  PI_Kinase UniProtKB/TrEMBL
  PX_dom UniProtKB/TrEMBL
  PX_dom_sf UniProtKB/TrEMBL
  PX_PI3K_C2_alpha UniProtKB/TrEMBL
  Ubiquitin-like_domsf UniProtKB/TrEMBL
KEGG Report cfa:485399 UniProtKB/TrEMBL
NCBI Gene PIK3C2A ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 4-PHOSPHATE 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT ALPHA UniProtKB/TrEMBL
  PTHR10048 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PF00787 UniProtKB/TrEMBL
  PI3_PI4_kinase UniProtKB/TrEMBL
  PI3K_C2 UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
PROSITE C2_PI3K UniProtKB/TrEMBL
  PI3_4_KINASE_1 UniProtKB/TrEMBL
  PI3_4_KINASE_2 UniProtKB/TrEMBL
  PI3_4_KINASE_3 UniProtKB/TrEMBL
  PI3K_RBD UniProtKB/TrEMBL
  PIK_HELICAL UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
  PS50195 UniProtKB/TrEMBL
SMART PI3K_C2 UniProtKB/TrEMBL
  PI3K_rbd UniProtKB/TrEMBL
  PI3Ka UniProtKB/TrEMBL
  PI3Kc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
  SM00312 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF54236 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
  SSF64268 UniProtKB/TrEMBL
UniProt A0A8C0RT86 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0TCG9_CANLF UniProtKB/TrEMBL
  A0A8C0TF33_CANLF UniProtKB/TrEMBL
  A0A8C0TFQ2_CANLF UniProtKB/TrEMBL
  A0A8I3PTV0_CANLF UniProtKB/TrEMBL
  A0A8I3Q0D7_CANLF UniProtKB/TrEMBL
  A0A8I3S670 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3SAR3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0NR49 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0P9R1_CANLF UniProtKB/TrEMBL
  A0A8P0P9U4_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:44551 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-21 PIK3C2A  phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha  LOC102154709  uncharacterized LOC102154709  Data merged from RGD:12164607 737654 PROVISIONAL