SLC27A5 (solute carrier family 27 member 5) - Rat Genome Database

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Gene: SLC27A5 (solute carrier family 27 member 5) Canis lupus familiaris
Analyze
Symbol: SLC27A5 (Ensembl: ZBTB45)
Name: solute carrier family 27 member 5
RGD ID: 12179013
Description: ENCODES a protein that exhibits cholate-CoA ligase activity (ortholog); fatty acid transmembrane transporter activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN bile acid biosynthetic process (ortholog); bile acid metabolic process (ortholog); establishment of localization in cell (ortholog); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; ASSOCIATED WITH genetic disease (ortholog); myoepithelioma (ortholog); FOUND IN basal plasma membrane (ortholog); endoplasmic reticulum membrane (ortholog); protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: bile acyl-CoA synthetase; LOC608675; solute carrier family 27 (fatty acid transporter), member 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1199,435,140 - 99,438,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,833,542 - 99,842,039 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01100,048,410 - 100,056,905 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1100,041,887 - 100,056,901 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,693,751 - 99,702,249 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0199,406,581 - 99,415,077 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01100,161,220 - 100,169,717 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
SLC27A5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1199,435,140 - 99,438,388 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha199,833,542 - 99,842,039 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01100,048,410 - 100,056,905 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1100,041,887 - 100,056,901 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1199,693,751 - 99,702,249 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0199,406,581 - 99,415,077 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01100,161,220 - 100,169,717 (+)NCBIUU_Cfam_GSD_1.0
SLC27A5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381958,498,333 - 58,511,992 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1958,479,512 - 58,512,413 (-)EnsemblGRCh38hg38GRCh38
GRCh371959,009,700 - 59,023,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361963,701,517 - 63,715,161 (-)NCBINCBI36Build 36hg18NCBI36
Build 341963,701,517 - 63,715,157NCBI
Celera1956,053,816 - 56,067,542 (-)NCBICelera
Cytogenetic Map19q13.43NCBI
HuRef1955,319,377 - 55,333,864 (-)NCBIHuRef
CHM1_11959,003,732 - 59,017,394 (-)NCBICHM1_1
T2T-CHM13v2.01961,594,402 - 61,607,985 (-)NCBIT2T-CHM13v2.0
Slc27a5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39712,722,273 - 12,732,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl712,722,273 - 12,732,119 (-)EnsemblGRCm39 Ensembl
GRCm38712,988,346 - 12,998,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl712,988,346 - 12,998,192 (-)EnsemblGRCm38mm10GRCm38
MGSCv37713,573,695 - 13,583,541 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36711,888,532 - 11,898,329 (-)NCBIMGSCv36mm8
Celera710,613,981 - 10,626,137 (-)NCBICelera
Cytogenetic Map7A1NCBI
cM Map77.71NCBI
Slc27a5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8182,688,742 - 82,699,335 (-)NCBIGRCr8
mRatBN7.2173,616,556 - 73,627,149 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl173,616,564 - 73,627,172 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx178,996,966 - 79,007,611 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0187,561,304 - 87,571,949 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0180,752,046 - 80,762,691 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0165,576,599 - 65,587,192 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl165,576,535 - 65,587,186 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,387,832 - 66,398,425 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4172,924,630 - 72,935,223 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1173,002,740 - 73,013,332 (+)NCBI
Celera160,212,177 - 60,222,770 (+)NCBICelera
Cytogenetic Map1q21NCBI
Slc27a5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555841,112,117 - 1,121,323 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555841,112,387 - 1,121,500 (-)NCBIChiLan1.0ChiLan1.0
SLC27A5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22064,768,032 - 64,788,131 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11966,555,906 - 66,576,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01955,507,455 - 55,520,448 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11964,329,567 - 64,342,630 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1964,329,567 - 64,342,630 (-)Ensemblpanpan1.1panPan2
Slc27a5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118218,019,774 - 218,029,145 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493706289,664 - 98,113 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493706290,217 - 98,562 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC27A5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl663,065,830 - 63,075,202 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1663,068,880 - 63,075,246 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SLC27A5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1650,782,713 - 50,793,816 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl650,781,544 - 50,792,515 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660454,088,423 - 4,092,128 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc27a5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462483284,552 - 92,556 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462483284,456 - 92,706 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC27A5
10 total Variants

Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_038466731   ⟹   XP_038322659
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1199,693,751 - 99,702,249 (+)NCBI
RefSeq Acc Id: XM_038527464   ⟹   XP_038383392
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01100,161,220 - 100,169,717 (+)NCBI
RefSeq Acc Id: XM_038591751   ⟹   XP_038447679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0199,406,581 - 99,415,077 (+)NCBI
RefSeq Acc Id: XM_038616371   ⟹   XP_038472299
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha199,833,542 - 99,842,039 (+)NCBI
RefSeq Acc Id: XM_038655556   ⟹   XP_038511484
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01100,048,410 - 100,056,905 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038322659   ⟸   XM_038466731
RefSeq Acc Id: XP_038447679   ⟸   XM_038591751
RefSeq Acc Id: XP_038511484   ⟸   XM_038655556
- UniProtKB: A0A8C0KLI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038472299   ⟸   XM_038616371
- UniProtKB: A0A8C0KLI0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038383392   ⟸   XM_038527464
- UniProtKB: A0A8C0KLI0 (UniProtKB/TrEMBL)
Protein Domains
AMP-binding enzyme C-terminal   AMP-dependent synthetase/ligase   BTB   C2H2-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00845000308 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00845000498.1 UniProtKB/TrEMBL
  ENSCAFT00845000509.1 UniProtKB/TrEMBL
  ENSCAFT00845000525.1 UniProtKB/TrEMBL
  ENSCAFT00845000536.1 UniProtKB/TrEMBL
  ENSCAFT00845000549.1 UniProtKB/TrEMBL
  ENSCAFT00845000561.1 UniProtKB/TrEMBL
  ENSCAFT00845000567 ENTREZGENE
  ENSCAFT00845000567.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.300.30 UniProtKB/TrEMBL
  3.40.50.12780 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
InterPro AMP-bd_C UniProtKB/TrEMBL
  AMP-bd_C_sf UniProtKB/TrEMBL
  AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
  BTB/POZ_dom UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
NCBI Gene LOC608675 ENTREZGENE
PANTHER LONG-CHAIN FATTY ACID TRANSPORT PROTEIN UniProtKB/TrEMBL
  PTHR43107:SF4 UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
  AMP-binding_C UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
  BTB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
  SSF54695 UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A8C0KLI0 ENTREZGENE
  A0A8I3MAI7_CANLF UniProtKB/TrEMBL
  A0A8I3MAJ6_CANLF UniProtKB/TrEMBL
  A0A8I3MAR5_CANLF UniProtKB/TrEMBL
  A0A8I3MF14_CANLF UniProtKB/TrEMBL
  A0A8I3MFW7_CANLF UniProtKB/TrEMBL
  A0A8I3MV14_CANLF UniProtKB/TrEMBL
  A0A8I3RP23_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-14 SLC27A5  solute carrier family 27 member 5  SLC27A5  solute carrier family 27 member 5  Data merged from RGD:12067112 737654 PROVISIONAL
2021-01-12 SLC27A5  solute carrier family 27 member 5  LOC608675  bile acyl-CoA synthetase  Symbol and/or name change 5135510 APPROVED