LOC100856339 (phosphatidylinositol 3-kinase regulatory subunit gamma) - Rat Genome Database

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Gene: LOC100856339 (phosphatidylinositol 3-kinase regulatory subunit gamma) Canis lupus familiaris
Analyze
Symbol: LOC100856339 (Ensembl: PIK3R3)
Name: phosphatidylinositol 3-kinase regulatory subunit gamma (Ensembl:phosphoinositide-3-kinase regulatory subunit 3)
RGD ID: 12176558
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity (ortholog); INVOLVED IN insulin receptor signaling pathway (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FasL mediated signaling pathway; phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH Breast Cancer, Familial (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); colon adenocarcinoma (ortholog); FOUND IN phosphatidylinositol 3-kinase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoinositide-3-kinase regulatory subunit 3; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma); PIK3R3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,222,059 - 14,357,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,235,824 - 14,353,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,339,320 - 14,478,832 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,369,954 - 14,509,881 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,387,484 - 14,509,849 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,170,772 - 14,310,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,239,288 - 14,378,669 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,308,726 - 14,448,356 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC100856339
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,222,059 - 14,357,200 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,235,824 - 14,353,832 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,339,320 - 14,478,832 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,369,954 - 14,509,881 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,387,484 - 14,509,849 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,170,772 - 14,310,183 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,239,288 - 14,378,669 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,308,726 - 14,448,356 (+)NCBIUU_Cfam_GSD_1.0
PIK3R3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,040,140 - 46,174,901 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,040,140 - 46,133,036 (-)EnsemblGRCh38hg38GRCh38
GRCh37146,505,812 - 46,640,573 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,278,399 - 46,370,901 (-)NCBINCBI36Build 36hg18NCBI36
Build 34146,217,832 - 46,310,334NCBI
Celera144,793,099 - 44,886,009 (-)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef144,620,825 - 44,713,687 (-)NCBIHuRef
CHM1_1146,622,976 - 46,715,844 (-)NCBICHM1_1
T2T-CHM13v2.0145,917,331 - 46,052,095 (-)NCBIT2T-CHM13v2.0
Pik3r3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,078,593 - 116,160,253 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,030,581 - 116,157,038 (+)EnsemblGRCm39 Ensembl
GRCm39 Ensembl4116,078,815 - 116,160,253 (+)EnsemblGRCm39 Ensembl
GRCm384116,221,400 - 116,303,056 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,173,384 - 116,299,841 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,221,618 - 116,303,056 (+)EnsemblGRCm38mm10GRCm38
MGSCv374115,894,519 - 115,975,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,719,846 - 115,800,988 (+)NCBIMGSCv36mm8
Celera4114,959,917 - 115,043,525 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
Pik3r3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,936,790 - 135,009,303 (+)NCBIGRCr8
mRatBN7.25129,700,925 - 129,772,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,701,229 - 129,772,583 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,318,324 - 132,396,864 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,072,913 - 134,151,457 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,095,352 - 134,173,900 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,069,972 - 135,145,633 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,074,297 - 135,142,488 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,858,124 - 138,930,177 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,497,494 - 136,566,473 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15136,502,719 - 136,571,699 (+)NCBI
Celera5128,230,224 - 128,297,191 (+)NCBICelera
Cytogenetic Map5q35NCBI
PIK3R3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,672,682 - 180,765,512 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,814,236 - 179,907,088 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,345,946 - 45,481,031 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,700,153 - 46,835,812 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,700,153 - 46,792,920 (-)Ensemblpanpan1.1panPan2
Pik3r3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,270,346 - 61,346,909 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647427,095,100 - 27,171,252 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647427,095,125 - 27,171,416 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100511937
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6165,268,568 - 165,402,649 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16165,268,260 - 165,402,668 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,797,396 - 152,914,712 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,651,692 - 86,748,670 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2086,651,520 - 86,745,116 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603330,235,811 - 30,332,860 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in LOC100856339
928 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 3 15 12 8 9 3
Low 3 2 7 6 6 6 6 6 1 3
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005629040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014119571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022427996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022427997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038451596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038495814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038558198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038622073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038687816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000006956   ⟹   ENSCAFP00000006438
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,235,824 - 14,353,826 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000070776   ⟹   ENSCAFP00000061895
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1514,235,824 - 14,353,832 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845036212   ⟹   ENSCAFP00845028334
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1514,387,484 - 14,508,127 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845036298   ⟹   ENSCAFP00845028407
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1514,387,708 - 14,509,849 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845036364   ⟹   ENSCAFP00845028464
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1514,387,708 - 14,509,849 (+)Ensembl
RefSeq Acc Id: XM_038451576   ⟹   XP_038307504
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,357,026 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038451580   ⟹   XP_038307508
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,339,320 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038451583   ⟹   XP_038307511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,355,531 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038451585   ⟹   XP_038307513
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,344,037 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038451592   ⟹   XP_038307520
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,433,700 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038451596   ⟹   XP_038307524
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1514,435,152 - 14,478,832 (+)NCBI
RefSeq Acc Id: XM_038495809   ⟹   XP_038351737
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,188,266 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038495810   ⟹   XP_038351738
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,170,772 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038495811   ⟹   XP_038351739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,186,773 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038495812   ⟹   XP_038351740
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,175,497 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038495813   ⟹   XP_038351741
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,264,952 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038495814   ⟹   XP_038351742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11514,266,405 - 14,310,183 (+)NCBI
RefSeq Acc Id: XM_038558193   ⟹   XP_038414121
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,326,224 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038558194   ⟹   XP_038414122
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,308,726 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038558195   ⟹   XP_038414123
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,324,729 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038558196   ⟹   XP_038414124
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,313,453 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038558197   ⟹   XP_038414125
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,403,177 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038558198   ⟹   XP_038414126
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01514,404,630 - 14,448,356 (+)NCBI
RefSeq Acc Id: XM_038622068   ⟹   XP_038477996
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,256,781 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038622069   ⟹   XP_038477997
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,239,288 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038622070   ⟹   XP_038477998
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,255,286 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038622071   ⟹   XP_038477999
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,244,003 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038622072   ⟹   XP_038478000
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,333,485 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038622073   ⟹   XP_038478001
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01514,334,938 - 14,378,669 (+)NCBI
RefSeq Acc Id: XM_038687811   ⟹   XP_038543739
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,387,699 - 14,509,881 (+)NCBI
RefSeq Acc Id: XM_038687812   ⟹   XP_038543740
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,369,954 - 14,509,881 (+)NCBI
RefSeq Acc Id: XM_038687813   ⟹   XP_038543741
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,386,188 - 14,509,881 (+)NCBI
RefSeq Acc Id: XM_038687814   ⟹   XP_038543742
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,374,693 - 14,509,881 (+)NCBI
RefSeq Acc Id: XM_038687815   ⟹   XP_038543743
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,464,682 - 14,509,881 (+)NCBI
RefSeq Acc Id: XM_038687816   ⟹   XP_038543744
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01514,466,135 - 14,509,881 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038307504 (Get FASTA)   NCBI Sequence Viewer  
  XP_038307508 (Get FASTA)   NCBI Sequence Viewer  
  XP_038307511 (Get FASTA)   NCBI Sequence Viewer  
  XP_038307513 (Get FASTA)   NCBI Sequence Viewer  
  XP_038307520 (Get FASTA)   NCBI Sequence Viewer  
  XP_038307524 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351737 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351738 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351740 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351741 (Get FASTA)   NCBI Sequence Viewer  
  XP_038351742 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414121 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414122 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414123 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414124 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414125 (Get FASTA)   NCBI Sequence Viewer  
  XP_038414126 (Get FASTA)   NCBI Sequence Viewer  
  XP_038477996 (Get FASTA)   NCBI Sequence Viewer  
  XP_038477997 (Get FASTA)   NCBI Sequence Viewer  
  XP_038477998 (Get FASTA)   NCBI Sequence Viewer  
  XP_038477999 (Get FASTA)   NCBI Sequence Viewer  
  XP_038478000 (Get FASTA)   NCBI Sequence Viewer  
  XP_038478001 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543739 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543740 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543741 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543742 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543743 (Get FASTA)   NCBI Sequence Viewer  
  XP_038543744 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000006438.4
  ENSCAFP00000061895.1
  ENSCAFP00000073021.1
  ENSCAFP00030029663.1
  ENSCAFP00030029694.1
  ENSCAFP00030029797.1
  ENSCAFP00040026850.1
  ENSCAFP00040026894.1
  ENSCAFP00845028334.1
  ENSCAFP00845028407
  ENSCAFP00845028407.1
  ENSCAFP00845028464.1
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000006438   ⟸   ENSCAFT00000006956
RefSeq Acc Id: ENSCAFP00000061895   ⟸   ENSCAFT00000070776
RefSeq Acc Id: XP_038351738   ⟸   XM_038495810
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038351740   ⟸   XM_038495812
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038351739   ⟸   XM_038495811
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038351737   ⟸   XM_038495809
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038351741   ⟸   XM_038495813
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038351742   ⟸   XM_038495814
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038477997   ⟸   XM_038622069
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477999   ⟸   XM_038622071
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477998   ⟸   XM_038622070
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038477996   ⟸   XM_038622068
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038478000   ⟸   XM_038622072
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038478001   ⟸   XM_038622073
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038543740   ⟸   XM_038687812
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543742   ⟸   XM_038687814
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543741   ⟸   XM_038687813
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543739   ⟸   XM_038687811
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NUS5 (UniProtKB/TrEMBL),   A0A8C0R1N5 (UniProtKB/TrEMBL),   A0A8I3P519 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038543743   ⟸   XM_038687815
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038543744   ⟸   XM_038687816
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038307508   ⟸   XM_038451580
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038307513   ⟸   XM_038451585
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038307511   ⟸   XM_038451583
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038307504   ⟸   XM_038451576
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NUS5 (UniProtKB/TrEMBL),   A0A8C0R1N5 (UniProtKB/TrEMBL),   A0A8I3P519 (UniProtKB/TrEMBL),   A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038307520   ⟸   XM_038451592
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038307524   ⟸   XM_038451596
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038414122   ⟸   XM_038558194
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414124   ⟸   XM_038558196
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414123   ⟸   XM_038558195
- Peptide Label: isoform X2
- UniProtKB: A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8C0NR46 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414121   ⟸   XM_038558193
- Peptide Label: isoform X1
- UniProtKB: A0A8C0NP20 (UniProtKB/TrEMBL),   A0A8C0NUS5 (UniProtKB/TrEMBL),   A0A8C0R1N5 (UniProtKB/TrEMBL),   A0A8I3P519 (UniProtKB/TrEMBL),   A0A8I3P599 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038414125   ⟸   XM_038558197
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038414126   ⟸   XM_038558198
- Peptide Label: isoform X4
RefSeq Acc Id: ENSCAFP00845028407   ⟸   ENSCAFT00845036298
RefSeq Acc Id: ENSCAFP00845028334   ⟸   ENSCAFT00845036212
RefSeq Acc Id: ENSCAFP00845028464   ⟸   ENSCAFT00845036364
Protein Domains
SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000004331 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018424 UniProtKB/TrEMBL
  ENSCAFG00040016720 UniProtKB/TrEMBL
  ENSCAFG00845020552 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000006956.5 UniProtKB/TrEMBL
  ENSCAFT00000070776.2 UniProtKB/TrEMBL
  ENSCAFT00000109729.1 UniProtKB/TrEMBL
  ENSCAFT00030034016.1 UniProtKB/TrEMBL
  ENSCAFT00030034053.1 UniProtKB/TrEMBL
  ENSCAFT00030034173.1 UniProtKB/TrEMBL
  ENSCAFT00040030894.1 UniProtKB/TrEMBL
  ENSCAFT00040030944.1 UniProtKB/TrEMBL
  ENSCAFT00845036212.1 UniProtKB/TrEMBL
  ENSCAFT00845036298 ENTREZGENE
  ENSCAFT00845036298.1 UniProtKB/TrEMBL
  ENSCAFT00845036364.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/TrEMBL
InterPro PI3K_P85_iSH2 UniProtKB/TrEMBL
  PI3kinase_P85_cSH2 UniProtKB/TrEMBL
  PI3kinase_P85_nSH2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
NCBI Gene PIK3R3 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/TrEMBL
  PI3K21B, ISOFORM B UniProtKB/TrEMBL
Pfam PI3K_P85_iSH2 UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PRINTS PI3KINASEP85 UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/TrEMBL
PROSITE SH2 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
Superfamily-SCOP SSF55550 UniProtKB/TrEMBL
UniProt A0A8C0NP20 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NR46 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0NUS5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0R1N5 ENTREZGENE
  A0A8I3P519 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P599 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3PD50_CANLF UniProtKB/TrEMBL
  A0A8P0N776_CANLF UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-01-12 LOC100856339  phosphatidylinositol 3-kinase regulatory subunit gamma  PIK3R3  phosphoinositide-3-kinase regulatory subunit 3  Symbol and/or name change 5135510 APPROVED