TMEM183A (transmembrane protein 183A) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TMEM183A (transmembrane protein 183A) Canis lupus familiaris
Analyze
Symbol: TMEM183A
Name: transmembrane protein 183A
RGD ID: 12147532
Description: INVOLVED IN regulation of protein stability (inferred); ASSOCIATED WITH familial adult myoclonic epilepsy 5 (ortholog); gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); FOUND IN membrane (inferred); SCF ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transmembrane protein 183-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17166,640 - 180,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7166,974 - 180,660 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7222,297 - 236,341 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07177,085 - 191,140 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7177,096 - 191,163 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17165,322 - 179,368 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07274,851 - 288,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07297,360 - 311,411 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TMEM183A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17166,640 - 180,680 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7166,974 - 180,660 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7222,297 - 236,341 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.07177,085 - 191,140 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl7177,096 - 191,163 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.17165,322 - 179,368 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.07274,851 - 288,898 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.07297,360 - 311,411 (-)NCBIUU_Cfam_GSD_1.0
TMEM183A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,007,374 - 203,024,848 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1203,007,374 - 203,024,848 (+)EnsemblGRCh38hg38GRCh38
GRCh371202,976,502 - 202,993,976 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,243,159 - 201,259,291 (+)NCBINCBI36Build 36hg18NCBI36
Build 341199,708,192 - 199,724,324NCBI
Celera1176,105,772 - 176,122,430 (+)NCBICelera
Cytogenetic Map1q32.1NCBI
HuRef1174,142,136 - 174,158,805 (+)NCBIHuRef
CHM1_11204,398,835 - 204,415,499 (+)NCBICHM1_1
T2T-CHM13v2.01202,270,081 - 202,287,572 (+)NCBIT2T-CHM13v2.0
Tmem183a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,273,834 - 134,289,765 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1134,273,835 - 134,289,717 (-)EnsemblGRCm39 Ensembl
GRCm381134,346,096 - 134,362,012 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,346,097 - 134,361,979 (-)EnsemblGRCm38mm10GRCm38
MGSCv371136,242,674 - 136,258,576 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361136,161,788 - 136,178,366 (-)NCBIMGSCv36mm8
Celera1136,958,158 - 136,974,087 (-)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.2NCBI
Tmem183a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81348,355,664 - 48,372,437 (-)NCBIGRCr8
mRatBN7.21345,803,641 - 45,820,409 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1345,803,639 - 45,820,375 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1348,412,387 - 48,427,608 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01349,700,452 - 49,715,674 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01346,965,560 - 46,980,595 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01351,184,647 - 51,201,401 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1351,184,629 - 51,201,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01356,240,994 - 56,257,741 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,303,577 - 47,318,813 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11347,317,621 - 47,332,856 (-)NCBI
Celera1346,133,069 - 46,148,305 (-)NCBICelera
Cytogenetic Map13q13NCBI
Tmem183a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,029,390 - 39,046,339 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,029,390 - 39,044,502 (+)NCBIChiLan1.0ChiLan1.0
TMEM183A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2146,353,403 - 46,371,530 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1146,320,432 - 46,337,909 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01178,608,896 - 178,626,376 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11182,903,891 - 182,921,091 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,903,898 - 182,919,283 (+)Ensemblpanpan1.1panPan2
Tmem183a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,332,097 - 72,343,737 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365671,568,098 - 1,578,392 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365671,566,773 - 1,578,420 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM183A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,713,032 - 113,725,847 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,713,046 - 113,726,645 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,173,389 - 125,185,839 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM183A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,329,213 - 26,346,850 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2526,328,841 - 26,346,750 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605527,104,474 - 27,122,123 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem183a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248077,807,543 - 7,822,825 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248077,807,543 - 7,822,789 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in TMEM183A
60 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 22 6 6 6 6 1 12 8 10 6
Low 5
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005622166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038480510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038541837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038605966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038670676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_537117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000016418   ⟹   ENSCAFP00000015188
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl7166,974 - 180,660 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845025952   ⟹   ENSCAFP00845020457
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl7177,096 - 191,163 (-)Ensembl
RefSeq Acc Id: XM_005622166   ⟹   XP_005622223
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.17166,640 - 180,680 (-)NCBI
Dog10K_Boxer_Tasha7222,297 - 236,340 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038480508   ⟹   XP_038336436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.17165,322 - 179,366 (-)NCBI
RefSeq Acc Id: XM_038480509   ⟹   XP_038336437
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.17165,322 - 179,367 (-)NCBI
RefSeq Acc Id: XM_038480510   ⟹   XP_038336438
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.17165,322 - 179,368 (-)NCBI
RefSeq Acc Id: XM_038541835   ⟹   XP_038397763
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.07297,360 - 311,409 (-)NCBI
RefSeq Acc Id: XM_038541836   ⟹   XP_038397764
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.07297,360 - 311,410 (-)NCBI
RefSeq Acc Id: XM_038541837   ⟹   XP_038397765
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.07297,360 - 311,411 (-)NCBI
RefSeq Acc Id: XM_038560493   ⟹   XP_038416421
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha7222,297 - 236,341 (-)NCBI
RefSeq Acc Id: XM_038605964   ⟹   XP_038461892
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.07274,851 - 288,896 (-)NCBI
RefSeq Acc Id: XM_038605965   ⟹   XP_038461893
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.07274,851 - 288,897 (-)NCBI
RefSeq Acc Id: XM_038605966   ⟹   XP_038461894
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.07274,851 - 288,898 (-)NCBI
RefSeq Acc Id: XM_038670674   ⟹   XP_038526602
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.07177,085 - 191,138 (-)NCBI
RefSeq Acc Id: XM_038670675   ⟹   XP_038526603
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.07177,085 - 191,139 (-)NCBI
RefSeq Acc Id: XM_038670676   ⟹   XP_038526604
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.07177,085 - 191,140 (-)NCBI
RefSeq Acc Id: XM_537117   ⟹   XP_537117
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.17166,640 - 180,679 (-)NCBI
Dog10K_Boxer_Tasha7222,297 - 236,339 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_005622223   ⟸   XM_005622166
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LUW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_537117   ⟸   XM_537117
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0Y1 (UniProtKB/TrEMBL),   A0A8C0KQU8 (UniProtKB/TrEMBL),   A0A8I3RY51 (UniProtKB/TrEMBL),   A0A8C0LUW5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000015188   ⟸   ENSCAFT00000016418
RefSeq Acc Id: XP_038336438   ⟸   XM_038480510
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038336437   ⟸   XM_038480509
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038336436   ⟸   XM_038480508
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038461894   ⟸   XM_038605966
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038461893   ⟸   XM_038605965
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038461892   ⟸   XM_038605964
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038526604   ⟸   XM_038670676
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038526603   ⟸   XM_038670675
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038526602   ⟸   XM_038670674
- Peptide Label: isoform X1
- UniProtKB: A0A8C0M0Y1 (UniProtKB/TrEMBL),   A0A8C0KQU8 (UniProtKB/TrEMBL),   A0A8I3RY51 (UniProtKB/TrEMBL),   A0A8C0LUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416421   ⟸   XM_038560493
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038397765   ⟸   XM_038541837
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038397764   ⟸   XM_038541836
- Peptide Label: isoform X2
- UniProtKB: A0A8C0LUW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038397763   ⟸   XM_038541835
- Peptide Label: isoform X1
- UniProtKB: A0A8C0KQU8 (UniProtKB/TrEMBL),   A0A8C0LUW5 (UniProtKB/TrEMBL),   A0A8C0M0Y1 (UniProtKB/TrEMBL),   A0A8I3RY51 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845020457   ⟸   ENSCAFT00845025952

Promoters
RGD ID:13683856
Promoter ID:EPDNEW_C1924
Type:multiple initiation site
Name:TMEM183A_1
Description:transmembrane protein 183A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.17180,674 - 180,734EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000010330 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030002820 UniProtKB/TrEMBL
  ENSCAFG00040002551 UniProtKB/TrEMBL
  ENSCAFG00845014504 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000016418.5 UniProtKB/TrEMBL
  ENSCAFT00030005230.1 UniProtKB/TrEMBL
  ENSCAFT00040004854.1 UniProtKB/TrEMBL
  ENSCAFT00845025952 ENTREZGENE
  ENSCAFT00845025952.1 UniProtKB/TrEMBL
InterPro F-box-like_dom_sf UniProtKB/TrEMBL
  TMEM183 UniProtKB/TrEMBL
NCBI Gene TMEM183A ENTREZGENE
PANTHER PTHR20988 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 183A-RELATED UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
UniProt A0A8C0KQU8 ENTREZGENE
  A0A8C0LUW5 ENTREZGENE
  A0A8C0M0Y1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RY51 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:53838 ENTREZGENE