LORICRIN (loricrin cornified envelope precursor protein) - Rat Genome Database

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Gene: LORICRIN (loricrin cornified envelope precursor protein) Canis lupus familiaris
Analyze
Symbol: LORICRIN
Name: loricrin cornified envelope precursor protein
RGD ID: 12142007
Description: ENCODES a protein that exhibits structural constituent of cytoskeleton (ortholog); structural constituent of skin epidermis (ortholog); INVOLVED IN keratinocyte differentiation (ortholog); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 42 (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOR
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,994,297 - 61,995,591 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1761,460,176 - 61,463,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01763,144,507 - 63,147,606 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01761,944,715 - 61,947,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01762,703,311 - 62,706,427 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
LORICRIN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,994,297 - 61,995,591 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1761,460,176 - 61,463,150 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01763,144,507 - 63,147,606 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01761,944,715 - 61,947,725 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01762,703,311 - 62,706,427 (+)NCBIUU_Cfam_GSD_1.0
LORICRIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381153,259,687 - 153,262,124 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1153,259,687 - 153,262,124 (+)EnsemblGRCh38hg38GRCh38
GRCh371153,232,163 - 153,234,600 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361151,498,803 - 151,501,224 (+)NCBINCBI36Build 36hg18NCBI36
Build 341150,046,475 - 150,047,671NCBI
Celera1126,303,436 - 126,305,857 (+)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1124,595,566 - 124,597,999 (+)NCBIHuRef
CHM1_11154,627,959 - 154,630,380 (+)NCBICHM1_1
T2T-CHM13v2.01152,396,903 - 152,399,352 (+)NCBIT2T-CHM13v2.0
Loricrin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39391,987,578 - 91,990,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl391,987,578 - 91,990,449 (-)EnsemblGRCm39 Ensembl
GRCm38392,080,271 - 92,083,142 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl392,080,271 - 92,083,142 (-)EnsemblGRCm38mm10GRCm38
MGSCv37391,884,193 - 91,887,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36392,166,209 - 92,169,067 (-)NCBIMGSCv36mm8
Celera392,123,831 - 92,126,702 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map340.14NCBI
Loricrin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82180,253,674 - 180,256,572 (-)NCBIGRCr8
mRatBN7.22177,558,062 - 177,560,960 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2177,558,252 - 177,559,807 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2185,120,471 - 185,123,369 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02183,102,235 - 183,105,133 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02177,763,534 - 177,766,432 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02191,984,455 - 191,990,713 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2191,984,773 - 191,986,170 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02212,877,186 - 212,882,693 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42184,953,538 - 184,955,283 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2172,680,893 - 172,687,160 (+)NCBICelera
Cytogenetic Map2q34NCBI
Loricrin
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955592167,139 - 169,638 (-)NCBIChiLan1.0ChiLan1.0
LORICRIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,580,323 - 96,581,568 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,315,995 - 96,317,311 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01128,607,506 - 128,608,808 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LORICRIN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl496,304,070 - 96,305,110 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1496,303,835 - 96,308,016 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24105,206,034 - 105,209,187 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LORICRIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12010,494,570 - 10,497,944 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660389,966,739 - 9,968,274 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Loricrin
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624885675,955 - 677,391 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LORICRIN
22 total Variants

Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_022405020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038423237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038499723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038562291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038626382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_038423235   ⟹   XP_038279163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01763,144,507 - 63,147,606 (+)NCBI
RefSeq Acc Id: XM_038423236   ⟹   XP_038279164
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01763,144,713 - 63,147,606 (+)NCBI
RefSeq Acc Id: XM_038423237   ⟹   XP_038279165
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01763,144,507 - 63,147,606 (+)NCBI
RefSeq Acc Id: XM_038453501   ⟹   XP_038309429
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1761,460,176 - 61,463,150 (+)NCBI
RefSeq Acc Id: XM_038499718   ⟹   XP_038355646
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038499719   ⟹   XP_038355647
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038499720   ⟹   XP_038355648
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,821 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038499721   ⟹   XP_038355649
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038499722   ⟹   XP_038355650
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038499723   ⟹   XP_038355651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11761,893,634 - 61,896,464 (+)NCBI
RefSeq Acc Id: XM_038562290   ⟹   XP_038418218
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01762,703,311 - 62,706,427 (+)NCBI
RefSeq Acc Id: XM_038562291   ⟹   XP_038418219
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01762,703,516 - 62,706,427 (+)NCBI
RefSeq Acc Id: XM_038626380   ⟹   XP_038482308
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01761,944,715 - 61,947,725 (+)NCBI
RefSeq Acc Id: XM_038626381   ⟹   XP_038482309
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01761,944,715 - 61,947,725 (+)NCBI
RefSeq Acc Id: XM_038626382   ⟹   XP_038482310
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01761,944,919 - 61,947,725 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_038355647   ⟸   XM_038499719
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038355649   ⟸   XM_038499721
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038355650   ⟸   XM_038499722
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038355646   ⟸   XM_038499718
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038355651   ⟸   XM_038499723
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038355648   ⟸   XM_038499720
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038482308   ⟸   XM_038626380
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038482309   ⟸   XM_038626381
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038482310   ⟸   XM_038626382
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038279163   ⟸   XM_038423235
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038279165   ⟸   XM_038423237
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038279164   ⟸   XM_038423236
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038309429   ⟸   XM_038453501
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038418218   ⟸   XM_038562290
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038418219   ⟸   XM_038562291
- Peptide Label: isoform X10


Additional Information

Database Acc Id Source(s)
NCBI Gene LOR ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-10-22 LORICRIN  loricrin cornified envelope precursor protein  LOR  loricrin  Symbol and/or name change 5135510 APPROVED