SLC35B4 (solute carrier family 35 member B4) - Rat Genome Database

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Gene: SLC35B4 (solute carrier family 35 member B4) Canis lupus familiaris
Analyze
Symbol: SLC35B4
Name: solute carrier family 35 member B4
RGD ID: 12100948
Description: ENCODES a protein that exhibits UDP-N-acetylglucosamine transmembrane transporter activity (inferred); UDP-xylose transmembrane transporter activity (inferred); INVOLVED IN regulation of gluconeogenesis (ortholog); ASSOCIATED WITH genetic disease (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: nucleotide sugar transporter SLC35B4; UDP-xylose and UDP-N-acetylglucosamine transporter
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1143,120,901 - 3,166,622 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl143,120,934 - 3,149,926 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha142,777,771 - 2,806,756 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0142,850,661 - 2,896,364 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl142,850,651 - 2,884,651 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1143,054,439 - 3,083,441 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0142,799,262 - 2,828,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0142,945,417 - 2,974,427 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SLC35B4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1143,120,901 - 3,166,622 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl143,120,934 - 3,149,926 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha142,777,771 - 2,806,756 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0142,850,661 - 2,896,364 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl142,850,651 - 2,884,651 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1143,054,439 - 3,083,441 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0142,799,262 - 2,828,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0142,945,417 - 2,974,427 (+)NCBIUU_Cfam_GSD_1.0
SLC35B4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,289,332 - 134,320,338 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,289,332 - 134,316,930 (-)EnsemblGRCh38hg38GRCh38
GRCh377133,974,084 - 134,001,682 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367133,624,629 - 133,652,343 (-)NCBINCBI36Build 36hg18NCBI36
Build 347133,431,346 - 133,459,058NCBI
Celera7128,711,529 - 128,739,279 (-)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,275,903 - 128,303,642 (-)NCBIHuRef
CHM1_17133,908,420 - 133,936,166 (-)NCBICHM1_1
T2T-CHM13v2.07135,597,448 - 135,628,436 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,318,463 - 133,346,213 (-)NCBI
Slc35b4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,132,810 - 34,153,921 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,130,315 - 34,154,046 (-)EnsemblGRCm39 Ensembl
GRCm38634,155,872 - 34,177,054 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,153,380 - 34,177,111 (-)EnsemblGRCm38mm10GRCm38
MGSCv37634,105,879 - 34,127,054 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36634,086,037 - 34,107,212 (-)NCBIMGSCv36mm8
Celera634,153,134 - 34,174,309 (-)NCBICelera
Cytogenetic Map6A3.3NCBI
cM Map614.75NCBI
Slc35b4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8463,744,188 - 63,766,200 (-)NCBIGRCr8
mRatBN7.2462,776,993 - 62,799,013 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl462,776,993 - 62,799,003 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx467,727,672 - 67,749,623 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0463,643,398 - 63,665,349 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,045,805 - 62,067,760 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,550,995 - 61,573,003 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,550,995 - 61,573,003 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,271,551 - 61,293,559 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,480,810 - 61,502,818 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1461,759,346 - 61,778,774 (-)NCBI
Celera457,829,712 - 57,851,719 (-)NCBICelera
Cytogenetic Map4q22NCBI
Slc35b4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541033,695,499 - 33,723,694 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541033,695,985 - 33,728,749 (+)NCBIChiLan1.0ChiLan1.0
SLC35B4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26171,107,228 - 171,135,051 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1723,117,483 - 23,145,282 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,249,622 - 126,277,395 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17138,756,637 - 138,784,078 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7138,761,768 - 138,783,720 (-)Ensemblpanpan1.1panPan2
Slc35b4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511821,322,350 - 21,344,634 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365791,454,916 - 1,477,232 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365791,454,951 - 1,474,035 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC35B4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1814,880,765 - 14,911,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11814,880,322 - 14,916,406 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21815,800,876 - 15,820,562 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC35B4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121102,909,444 - 102,935,021 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21102,913,084 - 102,935,141 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666042413,088 - 435,566 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc35b4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247832,079,154 - 2,109,287 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247832,079,324 - 2,110,001 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SLC35B4
533 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 9 10 5
Low 5 5 13 6 6 6 6 6 2 8 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000002018   ⟹   ENSCAFP00000001866
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl143,120,934 - 3,149,926 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845026083   ⟹   ENSCAFP00845020566
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl142,850,651 - 2,884,651 (+)Ensembl
RefSeq Acc Id: NM_001185003   ⟹   NP_001171932
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1143,120,934 - 3,149,926 (+)NCBI
Dog10K_Boxer_Tasha142,777,771 - 2,806,756 (+)NCBI
ROS_Cfam_1.0142,850,661 - 2,879,654 (+)NCBI
UMICH_Zoey_3.1143,054,439 - 3,083,441 (+)NCBI
UNSW_CanFamBas_1.0142,799,262 - 2,828,250 (+)NCBI
UU_Cfam_GSD_1.0142,945,417 - 2,974,427 (+)NCBI
Sequence:
RefSeq Acc Id: XM_038685945   ⟹   XP_038541873
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0142,850,916 - 2,885,481 (+)NCBI
RefSeq Acc Id: XM_038685946   ⟹   XP_038541874
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0142,850,891 - 2,896,364 (+)NCBI
RefSeq Acc Id: XM_038685947   ⟹   XP_038541875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0142,850,890 - 2,896,364 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001171932   ⟸   NM_001185003
- UniProtKB: D6CJI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000001866   ⟸   ENSCAFT00000002018
RefSeq Acc Id: XP_038541875   ⟸   XM_038685947
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038541874   ⟸   XM_038685946
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038541873   ⟸   XM_038685945
- Peptide Label: isoform X1
RefSeq Acc Id: ENSCAFP00845020566   ⟸   ENSCAFT00845026083


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000001300 Ensembl
  ENSCAFG00000051961 UniProtKB/TrEMBL
  ENSCAFG00030012430 UniProtKB/TrEMBL
  ENSCAFG00040005274 UniProtKB/TrEMBL
  ENSCAFG00845014568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000099966.1 UniProtKB/TrEMBL
  ENSCAFT00030023036.1 UniProtKB/TrEMBL
  ENSCAFT00040009902.1 UniProtKB/TrEMBL
  ENSCAFT00845026083 ENTREZGENE
  ENSCAFT00845026083.1 UniProtKB/TrEMBL
InterPro UAA UniProtKB/TrEMBL
KEGG Report cfa:482249 UniProtKB/TrEMBL
NCBI Gene SLC35B4 ENTREZGENE
PANTHER PTHR10778 UniProtKB/TrEMBL
  UDP-XYLOSE AND UDP-N-ACETYLGLUCOSAMINE TRANSPORTER UniProtKB/TrEMBL
Pfam UAA UniProtKB/TrEMBL
UniProt A0A8C0N1P0_CANLF UniProtKB/TrEMBL
  A0A8I3RY68_CANLF UniProtKB/TrEMBL
  D6CJI2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:46367 ENTREZGENE