ZAP70 (zeta chain of T cell receptor associated protein kinase 70) - Rat Genome Database

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Gene: ZAP70 (zeta chain of T cell receptor associated protein kinase 70) Canis lupus familiaris
Analyze
Symbol: ZAP70
Name: zeta chain of T cell receptor associated protein kinase 70
RGD ID: 12092322
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); non-membrane spanning protein tyrosine kinase activity (inferred); INVOLVED IN alpha-beta T cell differentiation (ortholog); beta selection (ortholog); calcium-mediated signaling (ortholog); PARTICIPATES IN phosphatidylinositol 3-kinase class I signaling pathway; ASSOCIATED WITH combined immunodeficiency (ortholog); genetic disease (ortholog); immunodeficiency 48 (ortholog); FOUND IN cell-cell junction (inferred); cytoplasm (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein kinase ZAP-70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,887,416 - 44,913,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,887,433 - 44,900,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1044,814,558 - 44,845,740 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01045,763,554 - 45,794,709 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1045,763,556 - 45,786,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11045,475,442 - 45,506,585 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01045,761,536 - 45,792,714 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01045,944,828 - 45,975,965 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:19144411   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ZAP70
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11044,887,416 - 44,913,845 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1044,887,433 - 44,900,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1044,814,558 - 44,845,740 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01045,763,554 - 45,794,709 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1045,763,556 - 45,786,952 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11045,475,442 - 45,506,585 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01045,761,536 - 45,792,714 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01045,944,828 - 45,975,965 (-)NCBIUU_Cfam_GSD_1.0
ZAP70
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38297,713,576 - 97,756,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl297,713,576 - 97,739,862 (+)EnsemblGRCh38hg38GRCh38
GRCh37298,330,039 - 98,356,323 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36297,696,463 - 97,722,755 (+)NCBINCBI36Build 36hg18NCBI36
Build 34297,809,386 - 97,814,841NCBI
Celera292,533,995 - 92,560,286 (+)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef292,095,689 - 92,121,947 (+)NCBIHuRef
CHM1_1298,334,370 - 98,360,661 (+)NCBICHM1_1
T2T-CHM13v2.0298,171,200 - 98,202,543 (+)NCBIT2T-CHM13v2.0
Zap70
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39136,800,912 - 36,821,899 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl136,800,879 - 36,821,899 (+)EnsemblGRCm39 Ensembl
GRCm38136,761,798 - 36,782,821 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl136,761,798 - 36,782,818 (+)EnsemblGRCm38mm10GRCm38
MGSCv37136,818,706 - 36,839,661 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36136,706,407 - 36,727,362 (+)NCBIMGSCv36mm8
Celera136,542,193 - 36,563,340 (+)NCBICelera
Cytogenetic Map1BNCBI
cM Map115.41NCBI
Zap70
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8946,485,605 - 46,507,552 (+)NCBIGRCr8
mRatBN7.2938,989,750 - 39,011,701 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl938,989,750 - 39,011,700 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx947,492,671 - 47,514,535 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0952,608,543 - 52,630,495 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0950,890,437 - 50,912,386 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0943,331,149 - 43,353,097 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl943,331,155 - 43,353,113 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0942,980,050 - 43,002,015 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4935,693,089 - 35,715,071 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera936,755,106 - 36,777,088 (+)NCBICelera
Cytogenetic Map9q21NCBI
Zap70
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554704,386,311 - 4,396,419 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554704,379,260 - 4,397,851 (+)NCBIChiLan1.0ChiLan1.0
LOC100971372
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21230,715,251 - 30,745,868 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A30,718,013 - 30,748,630 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A101,582,567 - 101,613,175 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A98,613,740 - 98,639,742 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A98,613,740 - 98,639,088 (+)Ensemblpanpan1.1panPan2
LOC101971458
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,747,123 - 83,759,795 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367441,000,105 - 1,012,433 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367441,000,105 - 1,012,712 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZAP70
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl356,515,449 - 56,541,740 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1356,515,446 - 56,541,806 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2359,135,457 - 59,151,701 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103241092
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1141,403,294 - 1,430,205 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl141,404,325 - 1,431,015 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041168,846,354 - 168,873,240 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101716577
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247492,893,601 - 2,901,035 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247492,893,601 - 2,901,256 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZAP70
224 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 6 1
Low 5 22 6 6 6 6 8 9 6
Below cutoff 5 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005626046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038489098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038489099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038489100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038489101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038489102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038551091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038614999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038615000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038615001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038645564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038680377 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005332142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005365793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005400231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005415844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005433598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ409638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000003716   ⟹   ENSCAFP00000003440
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1044,887,433 - 44,899,436 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000083780   ⟹   ENSCAFP00000047083
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1044,887,433 - 44,900,071 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845038215   ⟹   ENSCAFP00845029933
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1045,763,556 - 45,786,952 (-)Ensembl
RefSeq Acc Id: XM_038489098   ⟹   XP_038345026
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,442 - 45,501,719 (-)NCBI
RefSeq Acc Id: XM_038489099   ⟹   XP_038345027
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,442 - 45,501,719 (-)NCBI
RefSeq Acc Id: XM_038489100   ⟹   XP_038345028
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,442 - 45,501,719 (-)NCBI
RefSeq Acc Id: XM_038489101   ⟹   XP_038345029
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,442 - 45,501,719 (-)NCBI
RefSeq Acc Id: XM_038489102   ⟹   XP_038345030
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,442 - 45,506,585 (-)NCBI
RefSeq Acc Id: XM_038551087   ⟹   XP_038407015
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,944,828 - 45,971,100 (-)NCBI
RefSeq Acc Id: XM_038551088   ⟹   XP_038407016
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,944,828 - 45,971,100 (-)NCBI
RefSeq Acc Id: XM_038551089   ⟹   XP_038407017
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,944,828 - 45,971,100 (-)NCBI
RefSeq Acc Id: XM_038551090   ⟹   XP_038407018
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,944,828 - 45,971,100 (-)NCBI
RefSeq Acc Id: XM_038551091   ⟹   XP_038407019
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,944,828 - 45,975,965 (-)NCBI
RefSeq Acc Id: XM_038614997   ⟹   XP_038470925
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,761,536 - 45,787,842 (-)NCBI
RefSeq Acc Id: XM_038614998   ⟹   XP_038470926
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,761,536 - 45,787,842 (-)NCBI
RefSeq Acc Id: XM_038614999   ⟹   XP_038470927
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,761,536 - 45,787,842 (-)NCBI
RefSeq Acc Id: XM_038615000   ⟹   XP_038470928
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,761,536 - 45,787,842 (-)NCBI
RefSeq Acc Id: XM_038615001   ⟹   XP_038470929
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,761,536 - 45,792,714 (-)NCBI
RefSeq Acc Id: XM_038645538   ⟹   XP_038501466
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,814,558 - 44,840,860 (-)NCBI
RefSeq Acc Id: XM_038645544   ⟹   XP_038501472
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,814,558 - 44,840,860 (-)NCBI
RefSeq Acc Id: XM_038645555   ⟹   XP_038501483
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,814,558 - 44,840,860 (-)NCBI
RefSeq Acc Id: XM_038645560   ⟹   XP_038501488
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,814,558 - 44,840,860 (-)NCBI
RefSeq Acc Id: XM_038645564   ⟹   XP_038501492
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,814,558 - 44,845,740 (-)NCBI
RefSeq Acc Id: XM_038680373   ⟹   XP_038536301
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,763,554 - 45,789,842 (-)NCBI
RefSeq Acc Id: XM_038680374   ⟹   XP_038536302
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,763,554 - 45,789,842 (-)NCBI
RefSeq Acc Id: XM_038680375   ⟹   XP_038536303
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,763,554 - 45,789,842 (-)NCBI
RefSeq Acc Id: XM_038680376   ⟹   XP_038536304
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,763,554 - 45,789,842 (-)NCBI
RefSeq Acc Id: XM_038680377   ⟹   XP_038536305
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,763,554 - 45,794,709 (-)NCBI
RefSeq Acc Id: XR_005332142
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11045,475,930 - 45,501,719 (-)NCBI
RefSeq Acc Id: XR_005365793
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01045,945,317 - 45,971,100 (-)NCBI
RefSeq Acc Id: XR_005400231
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01045,762,024 - 45,787,842 (-)NCBI
RefSeq Acc Id: XR_005415844
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1044,815,046 - 44,840,860 (-)NCBI
RefSeq Acc Id: XR_005433598
Type: NON-CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01045,764,042 - 45,789,842 (-)NCBI
Protein Sequences
Protein RefSeqs XP_038345026 (Get FASTA)   NCBI Sequence Viewer  
  XP_038345027 (Get FASTA)   NCBI Sequence Viewer  
  XP_038345028 (Get FASTA)   NCBI Sequence Viewer  
  XP_038345029 (Get FASTA)   NCBI Sequence Viewer  
  XP_038345030 (Get FASTA)   NCBI Sequence Viewer  
  XP_038407015 (Get FASTA)   NCBI Sequence Viewer  
  XP_038407016 (Get FASTA)   NCBI Sequence Viewer  
  XP_038407017 (Get FASTA)   NCBI Sequence Viewer  
  XP_038407018 (Get FASTA)   NCBI Sequence Viewer  
  XP_038407019 (Get FASTA)   NCBI Sequence Viewer  
  XP_038470925 (Get FASTA)   NCBI Sequence Viewer  
  XP_038470926 (Get FASTA)   NCBI Sequence Viewer  
  XP_038470927 (Get FASTA)   NCBI Sequence Viewer  
  XP_038470928 (Get FASTA)   NCBI Sequence Viewer  
  XP_038470929 (Get FASTA)   NCBI Sequence Viewer  
  XP_038501466 (Get FASTA)   NCBI Sequence Viewer  
  XP_038501472 (Get FASTA)   NCBI Sequence Viewer  
  XP_038501483 (Get FASTA)   NCBI Sequence Viewer  
  XP_038501488 (Get FASTA)   NCBI Sequence Viewer  
  XP_038501492 (Get FASTA)   NCBI Sequence Viewer  
  XP_038536301 (Get FASTA)   NCBI Sequence Viewer  
  XP_038536302 (Get FASTA)   NCBI Sequence Viewer  
  XP_038536303 (Get FASTA)   NCBI Sequence Viewer  
  XP_038536304 (Get FASTA)   NCBI Sequence Viewer  
  XP_038536305 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ACJ38124 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000047083.2
  ENSCAFP00030027776.1
  ENSCAFP00040029036.1
  ENSCAFP00845029933
  ENSCAFP00845029933.1
RefSeq Acc Id: ENSCAFP00000047083   ⟸   ENSCAFT00000083780
RefSeq Acc Id: ENSCAFP00000003440   ⟸   ENSCAFT00000003716
RefSeq Acc Id: XP_038345030   ⟸   XM_038489102
RefSeq Acc Id: XP_038345026   ⟸   XM_038489098
RefSeq Acc Id: XP_038345028   ⟸   XM_038489100
RefSeq Acc Id: XP_038345027   ⟸   XM_038489099
RefSeq Acc Id: XP_038345029   ⟸   XM_038489101
RefSeq Acc Id: XP_038470929   ⟸   XM_038615001
RefSeq Acc Id: XP_038470925   ⟸   XM_038614997
RefSeq Acc Id: XP_038470927   ⟸   XM_038614999
RefSeq Acc Id: XP_038470926   ⟸   XM_038614998
RefSeq Acc Id: XP_038470928   ⟸   XM_038615000
RefSeq Acc Id: XP_038536305   ⟸   XM_038680377
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536301   ⟸   XM_038680373
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536303   ⟸   XM_038680375
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536302   ⟸   XM_038680374
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038536304   ⟸   XM_038680376
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038501492   ⟸   XM_038645564
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038501466   ⟸   XM_038645538
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038501483   ⟸   XM_038645555
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038501472   ⟸   XM_038645544
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038501488   ⟸   XM_038645560
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407019   ⟸   XM_038551091
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407015   ⟸   XM_038551087
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407017   ⟸   XM_038551089
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407016   ⟸   XM_038551088
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038407018   ⟸   XM_038551090
- UniProtKB: A0A8C0LKY4 (UniProtKB/TrEMBL),   A0A8C0NJL6 (UniProtKB/TrEMBL),   A0A8C0SYR5 (UniProtKB/TrEMBL),   A0A8I3P8U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845029933   ⟸   ENSCAFT00845038215
Protein Domains
Protein kinase   SH2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000002371 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030017272 UniProtKB/TrEMBL
  ENSCAFG00040018051 UniProtKB/TrEMBL
  ENSCAFG00845021644 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000083780.2 UniProtKB/TrEMBL
  ENSCAFT00030031852.1 UniProtKB/TrEMBL
  ENSCAFT00040033361.1 UniProtKB/TrEMBL
  ENSCAFT00845038215 ENTREZGENE
  ENSCAFT00845038215.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Kinase_SYK/ZAP-70_inter-SH2_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SYK/ZAP-70_N_SH2 UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_non-rcpt_SYK/ZAP70 UniProtKB/TrEMBL
NCBI Gene ZAP70 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE ZAP-70 UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
PIRSF TyrPK_SYK UniProtKB/TrEMBL
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
SMART SH2 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP SSF55550 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8C0LKY4 ENTREZGENE
  A0A8C0NJL6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SYR5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P8U2 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:54555 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-04-24 ZAP70  zeta chain of T cell receptor associated protein kinase 70    tyrosine-protein kinase ZAP-70  Symbol and/or name change 5135510 APPROVED
2017-09-12 ZAP70  tyrosine-protein kinase ZAP-70    zeta-chain (TCR) associated protein kinase 70kDa  Symbol and/or name change 5135510 APPROVED