CCDC85C (coiled-coil domain containing 85C) - Rat Genome Database

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Gene: CCDC85C (coiled-coil domain containing 85C) Canis lupus familiaris
Analyze
Symbol: CCDC85C
Name: coiled-coil domain containing 85C
RGD ID: 12054722
Description: INVOLVED IN cell population proliferation (ortholog); cerebral cortex development (ortholog); establishment of cell polarity (ortholog); ASSOCIATED WITH genetic disease (ortholog); hydrocephalus (ortholog); INTELLECTUAL DEVELOPMENTAL DISORDER WITH HYPERTELORISM AND DISTINCTIVE FACIES (ortholog); FOUND IN adherens junction (inferred); apical junction complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil domain-containing protein 85C; SH3 and multiple ankyrin repeat domains protein 1-like
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,930,372 - 68,006,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,929,555 - 68,004,891 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,450,734 - 67,528,156 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,214,408 - 68,291,855 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,215,298 - 68,292,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,875,375 - 67,952,761 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,941,872 - 68,019,111 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,338,989 - 68,416,468 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:27457231   PMID:30032202  


Genomics

Comparative Map Data
CCDC85C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1867,930,372 - 68,006,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl867,929,555 - 68,004,891 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha867,450,734 - 67,528,156 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0868,214,408 - 68,291,855 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl868,215,298 - 68,292,190 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1867,875,375 - 67,952,761 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0867,941,872 - 68,019,111 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0868,338,989 - 68,416,468 (-)NCBIUU_Cfam_GSD_1.0
CCDC85C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381499,500,190 - 99,604,207 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1499,500,190 - 99,604,207 (-)EnsemblGRCh38hg38GRCh38
GRCh371499,966,527 - 100,070,544 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361499,046,540 - 99,140,110 (-)NCBINCBI36Build 36hg18NCBI36
Celera1480,032,485 - 80,125,607 (-)NCBICelera
Cytogenetic Map14q32.2NCBI
HuRef1480,161,003 - 80,254,066 (-)NCBIHuRef
CHM1_11499,915,361 - 100,008,351 (-)NCBICHM1_1
T2T-CHM13v2.01493,731,756 - 93,835,650 (-)NCBIT2T-CHM13v2.0
Ccdc85c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912108,169,858 - 108,244,111 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12108,169,861 - 108,241,684 (-)EnsemblGRCm39 Ensembl
GRCm3812108,203,599 - 108,277,852 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12108,203,602 - 108,275,425 (-)EnsemblGRCm38mm10GRCm38
MGSCv3712109,444,555 - 109,513,627 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612108,654,152 - 108,723,483 (-)NCBIMGSCv36mm8
Celera12109,446,564 - 109,515,546 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1259.23NCBI
Ccdc85c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86132,877,851 - 132,948,744 (-)NCBIGRCr8
mRatBN7.26127,113,440 - 127,184,328 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6127,113,442 - 127,184,371 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.06132,113,806 - 132,183,434 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06141,284,186 - 141,353,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46132,572,485 - 132,641,431 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6124,672,684 - 124,742,377 (-)NCBICelera
Cytogenetic Map6q32NCBI
Ccdc85c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543820,853,560 - 20,909,510 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543820,851,085 - 20,909,512 (-)NCBIChiLan1.0ChiLan1.0
CCDC85C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215100,666,643 - 100,760,232 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11499,883,139 - 99,976,695 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01480,134,889 - 80,229,717 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11499,458,198 - 99,550,546 (-)NCBIpanpan1.1PanPan1.1panPan2
Ccdc85c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086406,693,763 - 6,765,570 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366043,319,799 - 3,388,781 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366043,316,898 - 3,388,687 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC85C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7120,514,491 - 120,597,318 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17120,514,488 - 120,597,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27128,124,329 - 128,148,522 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCDC85C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12477,470,947 - 77,560,425 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2477,471,048 - 77,560,331 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605364,606,196 - 64,701,019 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccdc85c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247344,310,607 - 4,366,209 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247344,310,662 - 4,366,209 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCDC85C
1491 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 3 6 6 7 5
Low 3 2 16 6 6 6 2 5 5 6
Below cutoff 4 8

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000049160   ⟹   ENSCAFP00000036212
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl867,929,555 - 68,004,891 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845007100   ⟹   ENSCAFP00845005663
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl868,215,298 - 68,292,190 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845007116   ⟹   ENSCAFP00845005675
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl868,217,615 - 68,292,190 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845007126   ⟹   ENSCAFP00845005679
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl868,217,615 - 68,292,190 (-)Ensembl
RefSeq Acc Id: XM_038484185   ⟹   XP_038340113
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.1867,875,375 - 67,952,761 (-)NCBI
RefSeq Acc Id: XM_038545698   ⟹   XP_038401626
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.0868,338,989 - 68,416,468 (-)NCBI
RefSeq Acc Id: XM_038595310   ⟹   XP_038451238
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha867,450,734 - 67,528,156 (-)NCBI
RefSeq Acc Id: XM_038609793   ⟹   XP_038465721
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.0867,941,872 - 68,019,111 (-)NCBI
RefSeq Acc Id: XM_038674613   ⟹   XP_038530541
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0868,214,408 - 68,291,855 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSCAFP00000036212   ⟸   ENSCAFT00000049160
RefSeq Acc Id: XP_038340113   ⟸   XM_038484185
RefSeq Acc Id: XP_038465721   ⟸   XM_038609793
RefSeq Acc Id: XP_038530541   ⟸   XM_038674613
- UniProtKB: A0A8C0PNQ7 (UniProtKB/TrEMBL),   A0A8I3MUT5 (UniProtKB/TrEMBL),   A0A8C0KF42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038451238   ⟸   XM_038595310
- UniProtKB: A0A8C0PNQ7 (UniProtKB/TrEMBL),   A0A8I3MUT5 (UniProtKB/TrEMBL),   A0A8C0KF42 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038401626   ⟸   XM_038545698
- UniProtKB: A0A8C0KF42 (UniProtKB/TrEMBL),   A0A8C0MVK0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845005675   ⟸   ENSCAFT00845007116
RefSeq Acc Id: ENSCAFP00845005679   ⟸   ENSCAFT00845007126
RefSeq Acc Id: ENSCAFP00845005663   ⟸   ENSCAFT00845007100

Promoters
RGD ID:13684334
Promoter ID:EPDNEW_C2403
Type:multiple initiation site
Name:CCDC85C_1
Description:coiled-coil domain containing 85C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1868,004,852 - 68,004,912EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000028971 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030007572 UniProtKB/TrEMBL
  ENSCAFG00040000750 UniProtKB/TrEMBL
  ENSCAFG00845003940 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000049160.3 UniProtKB/TrEMBL
  ENSCAFT00000108036.1 UniProtKB/TrEMBL
  ENSCAFT00030013954.1 UniProtKB/TrEMBL
  ENSCAFT00040001385.1 UniProtKB/TrEMBL
  ENSCAFT00845007100 ENTREZGENE
  ENSCAFT00845007100.1 UniProtKB/TrEMBL
  ENSCAFT00845007116.1 UniProtKB/TrEMBL
  ENSCAFT00845007126.1 UniProtKB/TrEMBL
InterPro CCDC85 UniProtKB/TrEMBL
NCBI Gene CCDC85C ENTREZGENE
PANTHER COILED-COIL DOMAIN-CONTAINING PROTEIN 85C UniProtKB/TrEMBL
  PTHR13546 UniProtKB/TrEMBL
Pfam CCDC85 UniProtKB/TrEMBL
UniProt A0A8C0KF42 ENTREZGENE
  A0A8C0MVK0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PNQ7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MJS9_CANLF UniProtKB/TrEMBL
  A0A8I3MUT5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MUT7_CANLF UniProtKB/TrEMBL
  A0A8P0PP18_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:38864 ENTREZGENE