IL2RB (interleukin 2 receptor subunit beta) - Rat Genome Database

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Gene: IL2RB (interleukin 2 receptor subunit beta) Pan paniscus
Analyze
Symbol: IL2RB
Name: interleukin 2 receptor subunit beta
RGD ID: 12043423
Description: ENCODES a protein that exhibits interleukin-2 binding (ortholog); interleukin-2 receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; ASSOCIATED WITH adenylosuccinase lyase deficiency (ortholog); allergic disease (ortholog); Animal Toxoplasmosis (ortholog); FOUND IN cell surface (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: interleukin-2 receptor subunit beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22346,981,923 - 47,006,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,670,496 - 49,694,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,039,469 - 18,069,952 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,874,889 - 35,899,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,874,898 - 35,899,038 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
IL2RB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22346,981,923 - 47,006,008 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12249,670,496 - 49,694,590 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02218,039,469 - 18,069,952 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12235,874,889 - 35,899,038 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2235,874,898 - 35,899,038 (-)Ensemblpanpan1.1panPan2
IL2RB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382237,125,838 - 37,175,118 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2237,118,666 - 37,175,118 (-)EnsemblGRCh38hg38GRCh38
GRCh372237,521,878 - 37,571,158 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362235,851,824 - 35,875,908 (-)NCBINCBI36Build 36hg18NCBI36
Build 342235,846,381 - 35,870,462NCBI
Celera2221,322,955 - 21,347,014 (-)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2220,486,973 - 20,511,039 (-)NCBIHuRef
CHM1_12237,481,108 - 37,505,190 (-)NCBICHM1_1
T2T-CHM13v2.02237,585,773 - 37,635,037 (-)NCBIT2T-CHM13v2.0
Il2rb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391578,363,456 - 78,396,569 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1578,363,456 - 78,379,471 (-)EnsemblGRCm39 Ensembl
GRCm381578,479,256 - 78,511,621 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1578,479,256 - 78,495,271 (-)EnsemblGRCm38mm10GRCm38
MGSCv371578,310,978 - 78,325,496 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361578,307,803 - 78,322,277 (-)NCBIMGSCv36mm8
Celera1579,943,154 - 79,957,670 (-)NCBICelera
Cytogenetic Map15E1NCBI
cM Map1537.52NCBI
Il2rb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87111,913,828 - 111,928,537 (-)NCBIGRCr8
mRatBN7.27110,033,341 - 110,048,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7110,033,341 - 110,048,054 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7111,783,773 - 111,798,546 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07114,007,308 - 114,022,077 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07113,975,130 - 113,989,824 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07119,701,338 - 119,716,238 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7119,701,251 - 119,716,238 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07119,690,375 - 119,705,275 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera7106,371,243 - 106,385,925 (-)NCBICelera
Cytogenetic Map7q34NCBI
Il2rb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541323,623,154 - 23,640,259 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541323,623,567 - 23,640,245 (-)NCBIChiLan1.0ChiLan1.0
IL2RB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11027,370,797 - 27,388,775 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1027,370,797 - 27,388,775 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1027,325,543 - 27,343,512 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01028,162,844 - 28,180,818 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1028,162,844 - 28,180,812 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11027,884,492 - 27,902,458 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01028,193,229 - 28,211,199 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01028,371,136 - 28,389,104 (+)NCBIUU_Cfam_GSD_1.0
Il2rb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494510,785,491 - 10,797,317 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364923,795,940 - 3,805,774 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364923,795,940 - 3,805,822 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL2RB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl510,628,962 - 10,650,314 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1510,610,094 - 10,650,315 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.258,223,970 - 8,247,389 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL2RB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11919,830,919 - 19,853,534 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1919,828,898 - 19,852,988 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045105,975,766 - 105,999,423 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il2rb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475210,672,432 - 10,683,045 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475210,662,053 - 10,682,891 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000047818   ⟹   ENSPPAP00000024992
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2235,874,898 - 35,899,038 (-)Ensembl
RefSeq Acc Id: XM_003821552   ⟹   XP_003821600
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22346,981,923 - 47,006,008 (-)NCBI
NHGRI_mPanPan12249,670,496 - 49,694,590 (-)NCBI
Mhudiblu_PPA_v02218,039,485 - 18,063,560 (-)NCBI
PanPan1.12235,874,889 - 35,899,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034948516   ⟹   XP_034804407
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22346,981,923 - 47,003,108 (-)NCBI
NHGRI_mPanPan12249,670,496 - 49,691,691 (-)NCBI
Mhudiblu_PPA_v02218,039,469 - 18,060,672 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003821600 (Get FASTA)   NCBI Sequence Viewer  
  XP_034804407 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024992.1
Reference Protein Sequences
RefSeq Acc Id: XP_003821600   ⟸   XM_003821552
- UniProtKB: A0A2R9B5X3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034804407   ⟸   XM_034948516
- UniProtKB: A0A2R9B5X3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000024992   ⟸   ENSPPAT00000047818
Protein Domains
Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035648 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047818.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Hempt_rcpt_S_F1_CS UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  IL2RB_N1 UniProtKB/TrEMBL
KEGG Report pps:100992438 UniProtKB/TrEMBL
NCBI Gene IL2RB ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  INTERLEUKIN-2 RECEPTOR SUBUNIT BETA UniProtKB/TrEMBL
Pfam IL2RB_N1 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  HEMATOPO_REC_S_F1 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A2R9B5X3 ENTREZGENE, UniProtKB/TrEMBL