ACSL5 (acyl-CoA synthetase long chain family member 5) - Rat Genome Database

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Gene: ACSL5 (acyl-CoA synthetase long chain family member 5) Pan paniscus
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Symbol: ACSL5
Name: acyl-CoA synthetase long chain family member 5
RGD ID: 12031170
Description: ENCODES a protein that exhibits long-chain fatty acid-CoA ligase activity (ortholog); INVOLVED IN cellular response to insulin stimulus (ortholog); fatty acid transport (ortholog); long-chain fatty-acyl-CoA biosynthetic process (ortholog); PARTICIPATES IN fatty acid beta degradation pathway; ASSOCIATED WITH Diarrhea 13 (ortholog); Experimental Arthritis (ortholog); genetic disease (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: acyl-CoA synthetase long-chain family member 5; long-chain-fatty-acid--CoA ligase 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28124,252,488 - 124,305,741 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110124,257,822 - 124,307,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010108,965,559 - 109,019,240 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110112,405,069 - 112,457,892 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10112,407,161 - 112,457,892 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ACSL5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28124,252,488 - 124,305,741 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110124,257,822 - 124,307,922 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010108,965,559 - 109,019,240 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110112,405,069 - 112,457,892 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10112,407,161 - 112,457,892 (+)Ensemblpanpan1.1panPan2
ACSL5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810112,374,116 - 112,428,376 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10112,374,116 - 112,428,379 (+)EnsemblGRCh38hg38GRCh38
GRCh3710114,133,874 - 114,188,134 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610114,123,906 - 114,178,128 (+)NCBINCBI36Build 36hg18NCBI36
Celera10107,861,444 - 107,915,662 (+)NCBICelera
Cytogenetic Map10q25.2NCBI
HuRef10107,761,898 - 107,815,784 (+)NCBIHuRef
CHM1_110114,415,634 - 114,469,870 (+)NCBICHM1_1
T2T-CHM13v2.010113,265,142 - 113,319,056 (+)NCBIT2T-CHM13v2.0
Acsl5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391955,240,298 - 55,285,060 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1955,240,370 - 55,286,152 (+)EnsemblGRCm39 Ensembl
GRCm381955,251,861 - 55,296,628 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1955,251,938 - 55,297,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv371955,327,859 - 55,371,118 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361955,306,619 - 55,349,878 (+)NCBIMGSCv36mm8
Celera1957,444,332 - 57,487,767 (+)NCBICelera
Cytogenetic Map19D2NCBI
cM Map1951.3NCBI
Acsl5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81264,294,851 - 264,341,943 (+)NCBIGRCr8
mRatBN7.21254,289,513 - 254,336,608 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1254,292,521 - 254,336,607 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1262,494,531 - 262,541,592 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01269,200,609 - 269,247,672 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01261,848,340 - 261,895,280 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01276,240,703 - 276,290,012 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1276,240,703 - 276,290,008 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01283,637,899 - 283,685,361 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41261,554,383 - 261,599,373 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11261,765,427 - 261,810,418 (+)NCBI
Celera1249,999,118 - 250,043,312 (+)NCBICelera
Cytogenetic Map1q55NCBI
Acsl5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543117,477,086 - 17,524,539 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543117,477,113 - 17,524,539 (+)NCBIChiLan1.0ChiLan1.0
ACSL5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12823,437,838 - 23,478,763 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2823,440,387 - 23,478,762 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2823,589,635 - 23,630,543 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02823,970,117 - 24,011,237 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2823,971,931 - 24,069,062 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12823,527,397 - 23,568,302 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02823,538,540 - 23,579,462 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02823,737,237 - 23,775,914 (+)NCBIUU_Cfam_GSD_1.0
Acsl5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721322,569,123 - 22,610,342 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364862,967,522 - 2,991,154 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364862,952,379 - 2,992,148 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACSL5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14122,777,130 - 122,828,052 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114122,777,135 - 122,828,054 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214133,689,844 - 133,751,494 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACSL5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19105,259,546 - 105,311,500 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl9105,257,429 - 105,311,690 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604866,462,251 - 66,514,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acsl5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473734,038,518 - 34,091,661 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473734,038,610 - 34,091,579 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000003412   ⟹   ENSPPAP00000000729
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10112,407,161 - 112,457,892 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000003473   ⟹   ENSPPAP00000000737
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl10112,425,689 - 112,456,876 (+)Ensembl
RefSeq Acc Id: XM_003825589   ⟹   XP_003825637
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28124,252,488 - 124,305,741 (+)NCBI
NHGRI_mPanPan110124,257,822 - 124,307,922 (+)NCBI
Mhudiblu_PPA_v010108,968,141 - 109,019,240 (+)NCBI
PanPan1.110112,407,161 - 112,457,892 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055092281   ⟹   XP_054948256
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v28124,268,453 - 124,305,741 (+)NCBI
NHGRI_mPanPan110124,273,779 - 124,307,922 (+)NCBI
Protein Sequences
Protein RefSeqs XP_003825637 (Get FASTA)   NCBI Sequence Viewer  
  XP_054948256 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000000729
  ENSPPAP00000000729.1
  ENSPPAP00000000737.1
RefSeq Acc Id: XP_003825637   ⟸   XM_003825589
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z7G2 (UniProtKB/TrEMBL),   A0A2R8Z7B9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000000729   ⟸   ENSPPAT00000003412
RefSeq Acc Id: ENSPPAP00000000737   ⟸   ENSPPAT00000003473
RefSeq Acc Id: XP_054948256   ⟸   XM_055092281
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000002842 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000003412.1 UniProtKB/TrEMBL
  ENSPPAT00000003473.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.12780 UniProtKB/TrEMBL
InterPro AMP-binding_CS UniProtKB/TrEMBL
  AMP-dep_Synth/Lig UniProtKB/TrEMBL
  ANL_N_sf UniProtKB/TrEMBL
  LC-FACS_euk UniProtKB/TrEMBL
KEGG Report pps:100982029 UniProtKB/TrEMBL
NCBI Gene ACSL5 ENTREZGENE
PANTHER LONG-CHAIN-FATTY-ACID--COA LIGASE UniProtKB/TrEMBL
  LONG-CHAIN-FATTY-ACID--COA LIGASE 5 UniProtKB/TrEMBL
Pfam AMP-binding UniProtKB/TrEMBL
PROSITE AMP_BINDING UniProtKB/TrEMBL
Superfamily-SCOP Acetyl-CoA synthetase-like UniProtKB/TrEMBL
UniProt A0A2R8Z7B9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z7G2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-20 ACSL5  acyl-CoA synthetase long chain family member 5    acyl-CoA synthetase long-chain family member 5  Symbol and/or name change 5135510 APPROVED