EXT2 (exostosin glycosyltransferase 2) - Rat Genome Database

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Gene: EXT2 (exostosin glycosyltransferase 2) Pan paniscus
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Symbol: EXT2
Name: exostosin glycosyltransferase 2
RGD ID: 12007211
Description: ENCODES a protein that exhibits acetylglucosaminyltransferase activity (ortholog); N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN cellular response to fibroblast growth factor stimulus (ortholog); chondrocyte differentiation (ortholog); endochondral bone morphogenesis (ortholog); ASSOCIATED WITH genetic disease (ortholog); hepatoblastoma (ortholog); hereditary multiple exostoses (ortholog); FOUND IN catalytic complex (ortholog); Golgi apparatus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: exostosin 2; exostosin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,310,432 - 46,458,880 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,316,398 - 46,464,742 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,055,670 - 44,204,055 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,551,242 - 44,699,447 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,522,797 - 44,699,447 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
EXT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2946,310,432 - 46,458,880 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11146,316,398 - 46,464,742 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01144,055,670 - 44,204,055 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,551,242 - 44,699,447 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,522,797 - 44,699,447 (+)Ensemblpanpan1.1panPan2
EXT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381144,095,678 - 44,251,962 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1144,095,648 - 44,251,962 (+)EnsemblGRCh38hg38GRCh38
GRCh371144,117,228 - 44,273,512 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361144,073,675 - 44,223,556 (+)NCBINCBI36Build 36hg18NCBI36
Build 341144,073,674 - 44,223,555NCBI
Celera1144,264,389 - 44,414,268 (+)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1143,826,189 - 43,975,955 (+)NCBIHuRef
CHM1_11144,116,142 - 44,266,006 (+)NCBICHM1_1
T2T-CHM13v2.01144,251,025 - 44,407,303 (+)NCBIT2T-CHM13v2.0
Ext2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39293,525,978 - 93,652,913 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl293,491,373 - 93,652,913 (-)EnsemblGRCm39 Ensembl
GRCm38293,695,631 - 93,822,568 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl293,661,028 - 93,822,568 (-)EnsemblGRCm38mm10GRCm38
MGSCv37293,535,788 - 93,662,725 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36293,496,472 - 93,623,384 (-)NCBIMGSCv36mm8
Celera295,099,313 - 95,226,251 (-)NCBICelera
Cytogenetic Map2E1NCBI
cM Map251.62NCBI
Ext2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83100,120,776 - 100,253,424 (-)NCBIGRCr8
mRatBN7.2379,665,414 - 79,798,077 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl379,665,415 - 79,798,059 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx383,139,349 - 83,272,515 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0391,738,418 - 91,871,601 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0389,590,230 - 89,720,226 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0382,602,784 - 82,734,557 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl382,602,785 - 82,734,533 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0389,303,367 - 89,435,124 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4378,111,436 - 78,244,444 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1378,008,379 - 78,140,888 (-)NCBI
Celera378,867,721 - 79,000,170 (-)NCBICelera
Cytogenetic Map3q31NCBI
Ext2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554223,304,842 - 3,447,908 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554223,303,948 - 3,438,381 (-)NCBIChiLan1.0ChiLan1.0
EXT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11844,987,310 - 45,122,339 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1844,987,748 - 45,129,974 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1843,655,617 - 43,798,860 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01845,647,570 - 45,796,802 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1845,646,913 - 45,823,492 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11845,130,584 - 45,263,356 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01844,684,085 - 44,826,126 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01845,420,394 - 45,563,983 (-)NCBIUU_Cfam_GSD_1.0
Ext2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494722,233,504 - 22,377,538 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365624,342,874 - 4,489,180 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365624,345,146 - 4,489,180 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl218,209,102 - 18,232,025 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1218,099,790 - 18,239,229 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2219,709,056 - 19,849,479 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EXT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1121,077,159 - 21,282,317 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl121,119,987 - 21,281,635 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038118,305,404 - 118,502,345 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000060188   ⟹   ENSPPAP00000037288
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1144,522,797 - 44,698,304 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000060212   ⟹   ENSPPAP00000037312
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1144,522,797 - 44,539,355 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000060217   ⟹   ENSPPAP00000037317
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1144,551,242 - 44,699,447 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000060218   ⟹   ENSPPAP00000037318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1144,559,632 - 44,699,447 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000060230   ⟹   ENSPPAP00000037330
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1144,562,716 - 44,698,304 (+)Ensembl
RefSeq Acc Id: XM_003808219   ⟹   XP_003808267
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2946,310,993 - 46,458,880 (+)NCBI
NHGRI_mPanPan11146,316,935 - 46,464,742 (+)NCBI
Mhudiblu_PPA_v01144,056,311 - 44,204,053 (+)NCBI
PanPan1.11144,551,242 - 44,699,447 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960298   ⟹   XP_008958546
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2946,318,682 - 46,458,880 (+)NCBI
NHGRI_mPanPan11146,325,219 - 46,464,742 (+)NCBI
Mhudiblu_PPA_v01144,064,624 - 44,204,054 (+)NCBI
PanPan1.11144,559,632 - 44,699,447 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034932426   ⟹   XP_034788317
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2946,310,432 - 46,458,880 (+)NCBI
NHGRI_mPanPan11146,316,398 - 46,464,742 (+)NCBI
Mhudiblu_PPA_v01144,055,670 - 44,204,055 (+)NCBI
RefSeq Acc Id: XM_034932427   ⟹   XP_034788318
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2946,310,458 - 46,458,880 (+)NCBI
NHGRI_mPanPan11146,316,400 - 46,464,742 (+)NCBI
Mhudiblu_PPA_v01144,055,780 - 44,204,054 (+)NCBI
RefSeq Acc Id: XP_003808267   ⟸   XM_003808219
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CGJ5 (UniProtKB/TrEMBL),   A0A2R9C5Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958546   ⟸   XM_008960298
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C8P8 (UniProtKB/TrEMBL),   A0A2R9C5Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034788317   ⟸   XM_034932426
- Peptide Label: isoform X4
- UniProtKB: A0A2R9C5Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034788318   ⟸   XM_034932427
- Peptide Label: isoform X3
- UniProtKB: A0A2R9C5Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000037318   ⟸   ENSPPAT00000060218
RefSeq Acc Id: ENSPPAP00000037312   ⟸   ENSPPAT00000060212
RefSeq Acc Id: ENSPPAP00000037317   ⟸   ENSPPAT00000060217
RefSeq Acc Id: ENSPPAP00000037288   ⟸   ENSPPAT00000060188
RefSeq Acc Id: ENSPPAP00000037330   ⟸   ENSPPAT00000060230

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041401 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000060188.1 UniProtKB/TrEMBL
  ENSPPAT00000060217.1 UniProtKB/TrEMBL
  ENSPPAT00000060218.1 UniProtKB/TrEMBL
  ENSPPAT00000060230.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.640.10 UniProtKB/TrEMBL
  3.90.1150.10 UniProtKB/TrEMBL
InterPro Exostosin UniProtKB/TrEMBL
  Exostosin_GT47 UniProtKB/TrEMBL
  GT64 UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_major UniProtKB/TrEMBL
  PyrdxlP-dep_Trfase_small UniProtKB/TrEMBL
KEGG Report pps:100975712 UniProtKB/TrEMBL
NCBI Gene EXT2 ENTREZGENE
PANTHER ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/TrEMBL
  ACETYLGLUCOSAMINYLTRANSFERASE UniProtKB/TrEMBL
Pfam Exostosin UniProtKB/TrEMBL
  Glyco_transf_64 UniProtKB/TrEMBL
Superfamily-SCOP SSF53383 UniProtKB/TrEMBL
  SSF53448 UniProtKB/TrEMBL
UniProt A0A2R9C5Y7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C8L9_PANPA UniProtKB/TrEMBL
  A0A2R9C8P8 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CGJ5 ENTREZGENE, UniProtKB/TrEMBL