FMR1 (fragile X messenger ribonucleoprotein 1) - Rat Genome Database

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Gene: FMR1 (fragile X messenger ribonucleoprotein 1) Pan paniscus
Analyze
Symbol: FMR1
Name: fragile X messenger ribonucleoprotein 1
RGD ID: 11985828
Description: ENCODES a protein that exhibits chromatin binding (ortholog); dynein complex binding (ortholog); microtubule binding (ortholog); INVOLVED IN anterograde axonal transport (ortholog); cellular response to L-glutamate (ortholog); cellular response to potassium ion (ortholog); ASSOCIATED WITH alcohol use disorder (ortholog); anxiety disorder (ortholog); autism spectrum disorder (ortholog); FOUND IN axon (ortholog); axon terminus (ortholog); Cajal body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FMRP translational regulator 1; fragile X mental retardation 1; fragile X mental retardation protein 1; fragile X mental retardation protein 1 homolog; synaptic functional regulator FMR1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X147,227,441 - 147,266,218 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X147,231,048 - 147,269,765 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X136,937,889 - 136,976,828 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X147,366,713 - 147,405,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX147,365,748 - 147,405,321 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anterograde axonal transport  (ISO)
cellular response to L-glutamate  (ISO)
cellular response to potassium ion  (ISO)
cellular response to virus  (IEA)
central nervous system development  (ISO)
dendritic spine development  (ISO)
detection of mechanical stimulus involved in sensory perception  (ISO)
DNA repair  (IEA)
evoked excitatory postsynaptic potential  (ISO)
excitatory chemical synaptic transmission  (ISO)
glutamate receptor signaling pathway  (ISO)
inhibitory chemical synaptic transmission  (ISO)
intracellular glutamate homeostasis  (ISO)
locomotory exploration behavior  (ISO)
miRNA-mediated post-transcriptional gene silencing  (ISO)
modulation by host of viral RNA genome replication  (IEA)
mRNA export from nucleus  (IEA)
mRNA processing  (IEA)
mRNA transport  (IEA)
negative regulation of cytoplasmic translation  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of long-term synaptic depression  (ISO)
negative regulation of miRNA-mediated gene silencing  (IEA)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of neuron differentiation  (ISO)
negative regulation of protein processing  (ISO)
negative regulation of receptor internalization  (ISO)
negative regulation of synaptic vesicle exocytosis  (ISO)
negative regulation of translation  (IEA)
negative regulation of translational initiation  (ISO)
nervous system development  (IEA)
non-membrane-bounded organelle assembly  (IEA)
ovarian follicle development  (ISO)
positive regulation of dendritic spine development  (ISO)
positive regulation of filopodium assembly  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of intracellular transport of viral material  (IEA)
positive regulation of long-term neuronal synaptic plasticity  (ISO)
positive regulation of long-term synaptic depression  (ISO)
positive regulation of long-term synaptic potentiation  (ISO)
positive regulation of miRNA-mediated gene silencing  (IEA)
positive regulation of proteasomal protein catabolic process  (ISO)
positive regulation of protein phosphorylation  (IEA,ISO)
positive regulation of receptor internalization  (IEA)
positive regulation of synaptic transmission  (ISO)
positive regulation of translation  (IEA)
regulation of alternative mRNA splicing, via spliceosome  (IEA)
regulation of dendritic spine development  (IEA)
regulation of filopodium assembly  (IEA)
regulation of modification of synaptic structure  (ISO)
regulation of mRNA stability  (IEA)
regulation of neuronal action potential  (IEA,ISO)
regulation of neurotransmitter secretion  (ISO)
regulation of translation  (IEA)
regulation of translation at postsynapse, modulating synaptic transmission  (ISO)
regulation of translation at presynapse, modulating synaptic transmission  (ISO)
response to activity  (ISO)
response to cocaine  (ISO)
response to electrical stimulus  (ISO)
response to gonadotropin  (ISO)
response to interleukin-1  (ISO)
response to interleukin-17  (ISO)
response to light stimulus  (ISO)
RNA splicing  (IEA)
social behavior  (ISO)
stress granule assembly  (IEA)
transmission of nerve impulse  (ISO)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
FMR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X147,227,441 - 147,266,218 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X147,231,048 - 147,269,765 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X136,937,889 - 136,976,828 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X147,366,713 - 147,405,327 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX147,365,748 - 147,405,321 (+)Ensemblpanpan1.1panPan2
FMR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X147,911,919 - 147,951,125 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX147,911,919 - 147,951,125 (+)EnsemblGRCh38hg38GRCh38
GRCh37X146,993,437 - 147,032,645 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X146,801,201 - 146,840,303 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X146,699,054 - 146,738,157NCBI
CeleraX147,345,446 - 147,384,585 (+)NCBICelera
Cytogenetic MapXq27.3NCBI
HuRefX135,963,879 - 135,993,282 (+)NCBIHuRef
CHM1_1X146,904,323 - 146,943,501 (+)NCBICHM1_1
T2T-CHM13v2.0X146,176,547 - 146,215,797 (+)NCBIT2T-CHM13v2.0
Fmr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X67,722,144 - 67,761,569 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX67,722,147 - 67,761,569 (+)EnsemblGRCm39 Ensembl
GRCm38X68,678,536 - 68,717,963 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX68,678,541 - 68,717,963 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X65,931,730 - 65,971,138 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X51,835,932 - 51,875,340 (+)NCBIMGSCv36mm8
MGSCv36X64,939,220 - 64,978,628 (+)NCBIMGSCv36mm8
Cytogenetic MapXA7.1NCBI
cM MapX34.83NCBI
Fmr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X152,284,857 - 152,322,686 (+)NCBIGRCr8
mRatBN7.2X147,240,239 - 147,278,057 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX147,240,301 - 147,278,050 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX149,444,285 - 149,482,036 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X152,978,628 - 153,016,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X150,519,276 - 150,557,027 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X154,684,924 - 154,722,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
RGSC_v3.4X154,756,031 - 154,793,782 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X154,829,463 - 154,867,215 (+)NCBI
Cytogenetic MapXq37NCBI
Fmr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955498566,688 - 595,360 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955498566,741 - 594,837 (+)NCBIChiLan1.0ChiLan1.0
FMR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X116,249,079 - 116,287,008 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX116,249,142 - 116,321,439 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX102,141,952 - 102,179,858 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X118,308,237 - 118,346,144 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX118,308,224 - 118,346,195 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X115,421,122 - 115,459,027 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X117,632,687 - 117,670,590 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X117,359,050 - 117,396,958 (+)NCBIUU_Cfam_GSD_1.0
Fmr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X114,286,773 - 114,324,847 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365131,289,558 - 1,327,856 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365131,290,038 - 1,327,850 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FMR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX120,361,367 - 120,399,831 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X120,361,232 - 120,400,282 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X137,792,642 - 137,831,753 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FMR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X122,635,383 - 122,674,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX122,635,439 - 122,674,355 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606560,266,278 - 60,318,872 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fmr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624883645,449 - 682,292 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624883645,524 - 681,705 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003806816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003806817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_003806818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957826 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008957845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014343569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055106619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055106620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055106621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057301144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_057301145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063601679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063601680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063601681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000061854   ⟹   ENSPPAP00000038945
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,365,748 - 147,405,321 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061858   ⟹   ENSPPAP00000038949
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,365,748 - 147,405,321 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061883   ⟹   ENSPPAP00000038974
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,366,744 - 147,403,036 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061887   ⟹   ENSPPAP00000038978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,366,744 - 147,387,969 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061891   ⟹   ENSPPAP00000038982
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,366,744 - 147,379,595 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000061893   ⟹   ENSPPAP00000038984
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 EnsemblX147,366,744 - 147,367,336 (+)Ensembl
RefSeq Acc Id: XM_003806817   ⟹   XP_003806865
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,442 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,048 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,405,268 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003806818   ⟹   XP_003806866
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,442 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,048 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,889 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,405,268 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957796   ⟹   XP_008956044
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,403,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957799   ⟹   XP_008956047
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,405,327 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957813   ⟹   XP_008956061
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,403,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957819   ⟹   XP_008956067
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,405,327 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957826   ⟹   XP_008956074
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,403,050 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957838   ⟹   XP_008956086
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,263,737 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,267,345 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,974,360 (+)NCBI
PanPan1.1X147,366,713 - 147,402,833 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008957845   ⟹   XP_008956093
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
Mhudiblu_PPA_v0X136,937,971 - 136,976,828 (+)NCBI
PanPan1.1X147,366,713 - 147,405,327 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055106619   ⟹   XP_054962594
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
RefSeq Acc Id: XM_055106620   ⟹   XP_054962595
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,337 (+)NCBI
RefSeq Acc Id: XM_055106621   ⟹   XP_054962596
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
RefSeq Acc Id: XM_057301144   ⟹   XP_057157127
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,441 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,048 - 147,269,765 (+)NCBI
RefSeq Acc Id: XM_057301145   ⟹   XP_057157128
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,452 - 147,266,218 (+)NCBI
NHGRI_mPanPan1X147,231,060 - 147,269,765 (+)NCBI
RefSeq Acc Id: XM_063601679   ⟹   XP_063457749
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,263,735 (+)NCBI
RefSeq Acc Id: XM_063601680   ⟹   XP_063457750
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
RefSeq Acc Id: XM_063601681   ⟹   XP_063457751
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2X147,227,454 - 147,266,218 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008956047   ⟸   XM_008957799
- Peptide Label: isoform X2
- UniProtKB: A0A2R9CAG1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008956067   ⟸   XM_008957819
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_008956093   ⟸   XM_008957845
- Peptide Label: isoform X9
- Sequence:
RefSeq Acc Id: XP_003806866   ⟸   XM_003806818
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_003806865   ⟸   XM_003806817
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008956044   ⟸   XM_008957796
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008956061   ⟸   XM_008957813
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008956074   ⟸   XM_008957826
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008956086   ⟸   XM_008957838
- Peptide Label: isoform X10
- Sequence:
RefSeq Acc Id: ENSPPAP00000038982   ⟸   ENSPPAT00000061891
RefSeq Acc Id: ENSPPAP00000038984   ⟸   ENSPPAT00000061893
RefSeq Acc Id: ENSPPAP00000038949   ⟸   ENSPPAT00000061858
RefSeq Acc Id: ENSPPAP00000038945   ⟸   ENSPPAT00000061854
RefSeq Acc Id: ENSPPAP00000038978   ⟸   ENSPPAT00000061887
RefSeq Acc Id: ENSPPAP00000038974   ⟸   ENSPPAT00000061883
RefSeq Acc Id: XP_054962594   ⟸   XM_055106619
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054962596   ⟸   XM_055106621
- Peptide Label: isoform X12
RefSeq Acc Id: XP_054962595   ⟸   XM_055106620
- Peptide Label: isoform X11
RefSeq Acc Id: XP_057157127   ⟸   XM_057301144
- Peptide Label: isoform X16
RefSeq Acc Id: XP_057157128   ⟸   XM_057301145
- Peptide Label: isoform X17
- UniProtKB: A0A2R9CAP9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063457750   ⟸   XM_063601680
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063457751   ⟸   XM_063601681
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063457749   ⟸   XM_063601679
- Peptide Label: isoform X13
Protein Domains
Agenet-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000041836 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000061854.1 UniProtKB/TrEMBL
  ENSPPAT00000061858.1 UniProtKB/TrEMBL
  ENSPPAT00000061883.1 UniProtKB/TrEMBL
  ENSPPAT00000061887.1 UniProtKB/TrEMBL
  ENSPPAT00000061891.1 UniProtKB/TrEMBL
  ENSPPAT00000061893.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
  3.30.1370.10 UniProtKB/TrEMBL
InterPro Agenet-like_dom UniProtKB/TrEMBL
  FMR1 UniProtKB/TrEMBL
  FMRP_KH0 UniProtKB/TrEMBL
  FXMR_C2 UniProtKB/TrEMBL
  FXMRP1_C_core UniProtKB/TrEMBL
  KH_dom UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  KH_I_FMR1_rpt1 UniProtKB/TrEMBL
  KH_I_FMR1_rpt2 UniProtKB/TrEMBL
  Tudor_Agenet_FMR1_rpt1 UniProtKB/TrEMBL
  Tudor_Agenet_FMR1_rpt2 UniProtKB/TrEMBL
  Tudor_FRX1 UniProtKB/TrEMBL
NCBI Gene FMR1 ENTREZGENE
PANTHER PTHR10603 UniProtKB/TrEMBL
  SYNAPTIC FUNCTIONAL REGULATOR FMR1 UniProtKB/TrEMBL
Pfam Agenet UniProtKB/TrEMBL
  FXMR_C2 UniProtKB/TrEMBL
  FXMRP1_C_core UniProtKB/TrEMBL
  KH_1 UniProtKB/TrEMBL
  KH_9 UniProtKB/TrEMBL
  Tudor_FRX1 UniProtKB/TrEMBL
PROSITE AGENET_LIKE UniProtKB/TrEMBL
  KH_TYPE_1 UniProtKB/TrEMBL
SMART SM00322 UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/TrEMBL
UniProt A0A2R9CAG1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CAP9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CAS3_PANPA UniProtKB/TrEMBL
  A0A2R9CAT5_PANPA UniProtKB/TrEMBL
  A0A2R9CDA2_PANPA UniProtKB/TrEMBL
  A0A2R9CLE9_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-02 FMR1  fragile X messenger ribonucleoprotein 1  FMR1  Fragile X messenger ribonucleoprotein 1  Symbol and/or name change 5135510 APPROVED
2022-04-05 FMR1  Fragile X messenger ribonucleoprotein 1  FMR1  FMRP translational regulator 1  Symbol and/or name change 5135510 APPROVED
2019-08-27 FMR1  FMRP translational regulator 1  FMR1  fragile X mental retardation 1  Symbol and/or name change 5135510 APPROVED