PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2) - Rat Genome Database

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Gene: PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2) Pan paniscus
Analyze
Symbol: PRKAG2
Name: protein kinase AMP-activated non-catalytic subunit gamma 2
RGD ID: 11980936
Description: ENCODES a protein that exhibits AMP binding (ortholog); AMP-activated protein kinase activity (ortholog); protein kinase binding (ortholog); INVOLVED IN regulation of catalytic activity (ortholog); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; ASSOCIATED WITH arrhythmogenic right ventricular dysplasia 9 (ortholog); cardiomyopathy (ortholog); congestive heart failure (ortholog); FOUND IN nucleotide-activated protein kinase complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 5'-AMP-activated protein kinase subunit gamma-2; LOC100989509; uncharacterized LOC100989509; uncharacterized protein LOC100989509
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,989,084 - 40,309,172 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07143,143,556 - 143,463,492 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17155,292,675 - 155,610,673 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,293,748 - 155,610,078 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PRKAG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1739,989,084 - 40,309,172 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07143,143,556 - 143,463,492 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17155,292,675 - 155,610,673 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7155,293,748 - 155,610,078 (-)Ensemblpanpan1.1panPan2
PRKAG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,556,127 - 151,877,115 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7151,556,124 - 151,877,214 (-)EnsemblGRCh38hg38GRCh38
GRCh377151,253,213 - 151,574,200 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,884,133 - 151,205,249 (-)NCBINCBI36Build 36hg18NCBI36
Build 347150,691,674 - 151,011,443NCBI
Celera7145,810,679 - 146,131,939 (-)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7145,065,108 - 145,385,764 (-)NCBIHuRef
CHM1_17151,261,930 - 151,582,980 (-)NCBICHM1_1
T2T-CHM13v2.07152,728,656 - 153,049,942 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27150,582,427 - 150,901,526 (-)NCBI
Prkag2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39525,067,733 - 25,311,576 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl525,067,742 - 25,305,640 (-)EnsemblGRCm39 Ensembl
GRCm38524,862,735 - 25,106,282 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl524,862,744 - 25,100,642 (-)EnsemblGRCm38mm10GRCm38
MGSCv37524,368,553 - 24,606,460 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36524,372,822 - 24,610,495 (-)NCBIMGSCv36mm8
Celera521,815,075 - 22,050,879 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.93NCBI
Prkag2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8410,744,695 - 10,985,939 (+)NCBIGRCr8
mRatBN7.2410,010,890 - 10,252,155 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl410,010,890 - 10,252,142 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx415,010,338 - 15,251,331 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0410,824,590 - 11,065,587 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.049,177,184 - 9,418,166 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.046,559,153 - 6,799,888 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl46,559,545 - 6,799,632 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.046,577,007 - 6,816,813 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.445,620,992 - 5,667,438 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.145,620,991 - 5,667,437 (+)NCBI
Celera470,878 - 117,245 (-)NCBICelera
Cytogenetic Map4q11NCBI
Prkag2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554915,852,082 - 6,019,318 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554915,852,534 - 6,048,820 (-)NCBIChiLan1.0ChiLan1.0
PRKAG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11615,521,304 - 15,786,237 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1615,522,111 - 15,785,854 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1616,128,157 - 16,392,728 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01617,243,089 - 17,508,262 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1617,243,090 - 17,508,234 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11615,615,142 - 15,879,767 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01616,196,295 - 16,461,149 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01616,247,524 - 16,513,015 (-)NCBIUU_Cfam_GSD_1.0
Prkag2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051185,735,796 - 5,995,632 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365276,909,044 - 7,167,600 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365276,907,723 - 7,168,222 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKAG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl185,475,077 - 5,744,657 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1185,475,077 - 5,744,761 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2186,107,245 - 6,143,586 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKAG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121119,738,976 - 120,058,831 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21119,738,967 - 119,970,972 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607215,710,451 - 16,034,583 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkag2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248004,968,866 - 5,207,501 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248004,969,010 - 5,207,941 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_024929478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034965294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055115544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063606426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000036180   ⟹   ENSPPAP00000013508
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7155,293,748 - 155,610,078 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000036184   ⟹   ENSPPAP00000013512
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl7155,293,748 - 155,472,266 (-)Ensembl
RefSeq Acc Id: XM_034965279   ⟹   XP_034821170
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,309,172 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,463,489 (-)NCBI
RefSeq Acc Id: XM_034965280   ⟹   XP_034821171
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,309,172 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,463,492 (-)NCBI
RefSeq Acc Id: XM_034965281   ⟹   XP_034821172
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,236,769 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,247,274 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,401,622 (-)NCBI
RefSeq Acc Id: XM_034965284   ⟹   XP_034821175
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,236,770 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,247,274 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,401,623 (-)NCBI
RefSeq Acc Id: XM_034965285   ⟹   XP_034821176
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBI
NHGRI_mPanPan1739,989,084 - 40,309,105 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,463,463 (-)NCBI
RefSeq Acc Id: XM_034965286   ⟹   XP_034821177
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,298,984 (-)NCBI
NHGRI_mPanPan1739,989,084 - 40,309,108 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,463,459 (-)NCBI
RefSeq Acc Id: XM_034965288   ⟹   XP_034821179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,160,862 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,169,471 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,323,562 (-)NCBI
RefSeq Acc Id: XM_034965289   ⟹   XP_034821180
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,160,862 (-)NCBI
NHGRI_mPanPan1739,989,084 - 40,169,471 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,323,743 (-)NCBI
RefSeq Acc Id: XM_034965290   ⟹   XP_034821181
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,160,862 (-)NCBI
NHGRI_mPanPan1739,989,084 - 40,169,471 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,323,743 (-)NCBI
RefSeq Acc Id: XM_034965291   ⟹   XP_034821182
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,054,951 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,065,764 (-)NCBI
Mhudiblu_PPA_v07143,143,556 - 143,220,245 (-)NCBI
RefSeq Acc Id: XM_055115544   ⟹   XP_054971519
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,160,862 (-)NCBI
NHGRI_mPanPan1739,990,964 - 40,169,471 (-)NCBI
RefSeq Acc Id: XM_063606426   ⟹   XP_063462496
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26187,978,818 - 188,097,792 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034821171   ⟸   XM_034965280
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821170   ⟸   XM_034965279
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821176   ⟸   XM_034965285
- Peptide Label: isoform X4
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821177   ⟸   XM_034965286
- Peptide Label: isoform X5
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821175   ⟸   XM_034965284
- Peptide Label: isoform X3
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821172   ⟸   XM_034965281
- Peptide Label: isoform X3
- UniProtKB: A0A2R9A899 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821181   ⟸   XM_034965290
- Peptide Label: isoform X9
- UniProtKB: A0A2R9ADD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821180   ⟸   XM_034965289
- Peptide Label: isoform X8
- UniProtKB: A0A2R9ADD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821179   ⟸   XM_034965288
- Peptide Label: isoform X6
- UniProtKB: A0A2R9ADD7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034821182   ⟸   XM_034965291
- Peptide Label: isoform X11
RefSeq Acc Id: ENSPPAP00000013512   ⟸   ENSPPAT00000036184
RefSeq Acc Id: ENSPPAP00000013508   ⟸   ENSPPAT00000036180
RefSeq Acc Id: XP_054971519   ⟸   XM_055115544
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063462496   ⟸   XM_063606426
- Peptide Label: isoform X10
Protein Domains
CBS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029923 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036180.1 UniProtKB/TrEMBL
  ENSPPAT00000036184.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.580.10 UniProtKB/TrEMBL
InterPro CBS_dom UniProtKB/TrEMBL
  CBS_dom_sf UniProtKB/TrEMBL
NCBI Gene PRKAG2 ENTREZGENE
PANTHER AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT UniProtKB/TrEMBL
  PTHR13780:SF122 UniProtKB/TrEMBL
Pfam CBS UniProtKB/TrEMBL
PROSITE CBS UniProtKB/TrEMBL
SMART CBS UniProtKB/TrEMBL
Superfamily-SCOP SSF54631 UniProtKB/TrEMBL
UniProt A0A2R9A899 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9ADD7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-08 PRKAG2  protein kinase AMP-activated non-catalytic subunit gamma 2  LOC100989509  uncharacterized LOC100989509  Data merged from RGD:11768515 737654 PROVISIONAL