ACP2 (acid phosphatase 2, lysosomal) - Rat Genome Database

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Gene: ACP2 (acid phosphatase 2, lysosomal) Pan paniscus
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Symbol: ACP2
Name: acid phosphatase 2, lysosomal
RGD ID: 11968362
Description: ENCODES a protein that exhibits acid phosphatase activity (ortholog); phosphoprotein phosphatase activity (ortholog); phosphotyrosine residue binding (ortholog); INVOLVED IN autophagic cell death (ortholog); lysosome organization (ortholog); response to cGMP (ortholog); PARTICIPATES IN autophagy pathway; ASSOCIATED WITH Acid Phosphatase Deficiency (ortholog); congenital disorder of glycosylation type IIc (ortholog); fetal akinesia deformation sequence syndrome 1 (ortholog); FOUND IN lysosomal lumen (inferred); lysosomal membrane (inferred); lysosome (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lysosomal acid phosphatase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,440,359 - 49,449,883 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,460,156 - 49,469,677 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01147,185,611 - 47,195,174 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,738,845 - 47,748,450 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,738,845 - 47,748,450 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
ACP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2949,440,359 - 49,449,883 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11149,460,156 - 49,469,677 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01147,185,611 - 47,195,174 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,738,845 - 47,748,450 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,738,845 - 47,748,450 (-)Ensemblpanpan1.1panPan2
ACP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381147,239,302 - 47,248,814 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1147,239,302 - 47,248,906 (-)EnsemblGRCh38hg38GRCh38
GRCh371147,260,853 - 47,270,365 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361147,217,429 - 47,226,939 (-)NCBINCBI36Build 36hg18NCBI36
Build 341147,217,428 - 47,226,939NCBI
Celera1147,400,080 - 47,409,684 (-)NCBICelera
Cytogenetic Map11p11.2NCBI
HuRef1146,959,833 - 46,969,437 (-)NCBIHuRef
CHM1_11147,259,545 - 47,269,147 (-)NCBICHM1_1
T2T-CHM13v2.01147,396,045 - 47,405,572 (-)NCBIT2T-CHM13v2.0
Acp2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39291,033,157 - 91,044,443 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl291,033,230 - 91,044,443 (+)EnsemblGRCm39 Ensembl
GRCm38291,202,812 - 91,214,098 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl291,202,885 - 91,214,098 (+)EnsemblGRCm38mm10GRCm38
MGSCv37291,043,069 - 91,054,255 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36291,003,769 - 91,012,982 (+)NCBIMGSCv36mm8
Celera292,588,418 - 92,599,572 (+)NCBICelera
Cytogenetic Map2E1NCBI
cM Map250.54NCBI
Acp2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8397,630,654 - 97,642,601 (+)NCBIGRCr8
mRatBN7.2377,175,022 - 77,185,180 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl377,175,895 - 77,185,680 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx380,654,465 - 80,663,379 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0389,253,472 - 89,262,386 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0387,104,531 - 87,113,457 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0380,020,346 - 80,030,365 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl380,021,440 - 80,030,363 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0386,729,100 - 86,739,118 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4375,559,522 - 75,568,415 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1375,455,893 - 75,464,787 (+)NCBI
Celera376,384,458 - 76,393,383 (+)NCBICelera
Cytogenetic Map3q24NCBI
Acp2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955422954,089 - 961,522 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955422954,108 - 961,522 (+)NCBIChiLan1.0ChiLan1.0
ACP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11842,346,207 - 42,356,447 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1842,345,608 - 42,354,352 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1841,074,892 - 41,082,823 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01843,000,686 - 43,008,615 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1843,000,671 - 43,010,921 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11842,486,567 - 42,494,663 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01842,042,164 - 42,050,092 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01842,771,565 - 42,779,495 (+)NCBIUU_Cfam_GSD_1.0
Acp2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494719,840,945 - 19,848,685 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365621,952,536 - 1,960,327 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365621,952,581 - 1,960,327 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl215,334,001 - 15,347,770 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1215,334,015 - 15,342,531 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2216,557,583 - 16,566,096 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1118,061,094 - 18,070,929 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl118,060,994 - 18,072,208 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038115,364,071 - 115,374,315 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acp2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247671,473,205 - 1,485,345 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247671,473,186 - 1,481,395 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000062271   ⟹   ENSPPAP00000039361
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,738,845 - 47,748,450 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062272   ⟹   ENSPPAP00000039362
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,739,659 - 47,748,338 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062273   ⟹   ENSPPAP00000039363
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,739,659 - 47,748,338 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062274   ⟹   ENSPPAP00000039364
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,739,659 - 47,748,063 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062275   ⟹   ENSPPAP00000039365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,744,762 - 47,748,338 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062276   ⟹   ENSPPAP00000039366
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1147,744,937 - 47,748,338 (-)Ensembl
RefSeq Acc Id: XM_003815183   ⟹   XP_003815231
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2949,440,359 - 49,449,883 (-)NCBI
NHGRI_mPanPan11149,460,156 - 49,469,677 (-)NCBI
Mhudiblu_PPA_v01147,185,611 - 47,195,174 (-)NCBI
PanPan1.11147,738,845 - 47,748,450 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034932570   ⟹   XP_034788461
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2949,440,359 - 49,446,854 (-)NCBI
NHGRI_mPanPan11149,460,156 - 49,466,651 (-)NCBI
Mhudiblu_PPA_v01147,185,611 - 47,195,160 (-)NCBI
RefSeq Acc Id: XP_003815231   ⟸   XM_003815183
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CBQ4 (UniProtKB/TrEMBL),   A0A2R9CMN4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034788461   ⟸   XM_034932570
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000039363   ⟸   ENSPPAT00000062273
RefSeq Acc Id: ENSPPAP00000039362   ⟸   ENSPPAT00000062272
RefSeq Acc Id: ENSPPAP00000039365   ⟸   ENSPPAT00000062275
RefSeq Acc Id: ENSPPAP00000039364   ⟸   ENSPPAT00000062274
RefSeq Acc Id: ENSPPAP00000039361   ⟸   ENSPPAT00000062271
RefSeq Acc Id: ENSPPAP00000039366   ⟸   ENSPPAT00000062276


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042373 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062271.1 UniProtKB/TrEMBL
  ENSPPAT00000062272.1 UniProtKB/TrEMBL
  ENSPPAT00000062273.1 UniProtKB/TrEMBL
  ENSPPAT00000062274.1 UniProtKB/TrEMBL
  ENSPPAT00000062275.1 UniProtKB/TrEMBL
  ENSPPAT00000062276.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1240 UniProtKB/TrEMBL
InterPro Acid_Pase_AS UniProtKB/TrEMBL
  His_Pase_clade-2 UniProtKB/TrEMBL
  His_PPase_superfam UniProtKB/TrEMBL
KEGG Report pps:100970546 UniProtKB/TrEMBL
NCBI Gene ACP2 ENTREZGENE
PANTHER ACID PHOSPHATASE-RELATED UniProtKB/TrEMBL
  LYSOSOMAL ACID PHOSPHATASE UniProtKB/TrEMBL
Pfam His_Phos_2 UniProtKB/TrEMBL
PROSITE HIS_ACID_PHOSPHAT_1 UniProtKB/TrEMBL
  HIS_ACID_PHOSPHAT_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF53254 UniProtKB/TrEMBL
UniProt A0A2R9CBQ1_PANPA UniProtKB/TrEMBL
  A0A2R9CBQ4 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CBQ9_PANPA UniProtKB/TrEMBL
  A0A2R9CBW1_PANPA UniProtKB/TrEMBL
  A0A2R9CED9_PANPA UniProtKB/TrEMBL
  A0A2R9CMN4 ENTREZGENE, UniProtKB/TrEMBL