SLC11A2 (solute carrier family 11 member 2)

Gene: SLC11A2 (solute carrier family 11 member 2) Pan paniscus

Analyze

Symbol:

SLC11A2

Name:

solute carrier family 11 member 2

RGD ID:

11954460

Description:

ENCODES a protein that exhibits cadmium ion binding (ortholog); cadmium ion transmembrane transporter activity (ortholog); calcium ion transmembrane transporter activity (ortholog); INVOLVED IN cellular response to hypoxia (ortholog); cellular response to iron ion (ortholog); cellular response to oxidative stress (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; iron uptake pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); anemia (ortholog); brain ischemia (ortholog); FOUND IN apical part of cell (ortholog); late endosome (ortholog); late endosome membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

natural resistance-associated macrophage protein 2; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	43,160,550 - 43,207,136 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	43,157,312 - 43,212,817 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	37,726,158 - 37,774,554 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	38,629,576 - 38,677,377 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	38,629,686 - 38,677,377 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amyotrophic lateral sclerosis (ISO)

anemia (ISO)

brain ischemia (ISO)

duodenal ulcer (ISO)

genetic disease (ISO)

hemochromatosis (ISO)

hypochromic anemia (ISO)

Hypochromic Microcytic Anemia with Iron Overload (ISO)

Hypochromic Microcytic Anemia with Iron Overload 1 (ISO)

iron deficiency anemia (ISO)

Iron Overload (ISO)

Liver Neoplasms (ISO)

Lung Injury (ISO)

Parkinson's disease (ISO)

Parkinsonism (ISO)

pneumonia (ISO)

restless legs syndrome (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cadmium ion transmembrane transport (IEA)

cellular response to hypoxia (ISO)

cellular response to iron ion (ISO)

cellular response to oxidative stress (ISO)

cellular response to tumor necrosis factor (ISO)

cobalt ion transport (IEA,ISO)

copper ion import across plasma membrane (ISO)

copper ion transmembrane transport (IEA)

copper ion transport (IEA)

dendrite morphogenesis (IEA,ISO)

detection of oxygen (ISO)

erythrocyte development (IEA,ISO)

establishment of localization in cell (IEA,ISO)

heme biosynthetic process (IEA,ISO)

iron import into cell (IEA,ISO)

iron ion transmembrane transport (IEA)

iron ion transport (IEA,ISO)

lead ion transport (IEA)

learning or memory (IEA,ISO)

manganese ion transmembrane transport (IEA)

manganese ion transport (IEA)

metal ion transport (IEA)

multicellular organismal-level iron ion homeostasis (IEA,ISO)

nickel cation transmembrane transport (IEA)

nickel cation transport (ISO)

porphyrin-containing compound biosynthetic process (IEA,ISO)

porphyrin-containing compound metabolic process (IEA,ISO)

proton transmembrane transport (IEA)

response to cadmium ion (ISO)

response to hypoxia (IEA,ISO)

response to iron ion (IEA,ISO)

response to lead ion (ISO)

response to manganese ion (ISO)

transition metal ion transport (ISO)

vanadium ion transport (ISO)

Cellular Component

apical part of cell (IEA,ISO)

apical plasma membrane (IEA)

basal part of cell (IEA)

brush border membrane (IEA)

cell surface (IEA)

cytoplasm (IEA)

cytoplasmic vesicle (IEA)

early endosome (IEA)

endosome (IEA)

extracellular vesicle (IEA)

late endosome (ISO)

late endosome membrane (IEA,ISO)

lysosomal membrane (IEA,ISO)

lysosome (ISO)

membrane (IEA)

mitochondrion (IEA)

nucleus (IEA)

paraferritin complex (IEA)

perinuclear region of cytoplasm (IEA)

plasma membrane (IEA)

recycling endosome (IEA)

trans-Golgi network (ISO)

vacuole (IEA)

Molecular Function

cadmium ion binding (IEA,ISO)

cadmium ion transmembrane transporter activity (IEA,ISO)

calcium ion transmembrane transporter activity (ISO)

chromium ion transmembrane transporter activity (ISO)

cobalt ion binding (ISO)

cobalt ion transmembrane transporter activity (IEA,ISO)

copper ion binding (ISO)

copper ion transmembrane transporter activity (IEA,ISO)

ferrous iron transmembrane transporter activity (IEA,ISO)

inorganic cation transmembrane transporter activity (ISO)

iron ion binding (ISO)

iron ion transmembrane transporter activity (ISO)

lead ion transmembrane transporter activity (IEA,ISO)

manganese ion binding (ISO)

manganese ion transmembrane transporter activity (IEA,ISO)

metal ion transmembrane transporter activity (IEA)

nickel cation binding (ISO)

nickel cation transmembrane transporter activity (IEA,ISO)

protein binding (ISO)

retromer complex binding (ISO)

solute:proton symporter activity (IEA)

transition metal ion transmembrane transporter activity (IEA)

vanadium ion transmembrane transporter activity (ISO)

zinc ion binding (ISO)

zinc ion transmembrane transporter activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

hypoxia inducible factor pathway (ISO)

iron uptake pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

SLC11A2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	43,160,550 - 43,207,136 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	43,157,312 - 43,212,817 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	37,726,158 - 37,774,554 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	38,629,576 - 38,677,377 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	38,629,686 - 38,677,377 (+)	Ensembl	panpan1.1		panPan2

SLC11A2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	50,952,263 - 51,028,886 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	50,979,401 - 51,028,566 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	51,373,190 - 51,422,669 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	49,666,044 - 49,706,409 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	49,666,043 - 49,706,409	NCBI
Celera	12	50,175,791 - 50,224,278 (-)	NCBI		Celera
Cytogenetic Map	12	q13.12	NCBI
HuRef	12	48,405,542 - 48,453,948 (-)	NCBI		HuRef
CHM1_1	12	51,339,878 - 51,388,358 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	12	50,915,621 - 50,992,224 (-)	NCBI		T2T-CHM13v2.0

Slc11a2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	100,285,779 - 100,322,090 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	100,285,779 - 100,322,953 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	100,387,898 - 100,424,209 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	100,387,898 - 100,425,072 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	100,218,329 - 100,253,486 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	100,215,932 - 100,251,017 (-)	NCBI		MGSCv36	mm8
Celera	15	102,539,003 - 102,574,160 (-)	NCBI		Celera
Cytogenetic Map	15	F1	NCBI
cM Map	15	56.29	NCBI

Slc11a2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	133,381,878 - 133,429,921 (-)	NCBI		GRCr8
mRatBN7.2	7	131,503,076 - 131,540,246 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	131,503,081 - 131,540,145 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	133,305,973 - 133,342,852 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	135,531,551 - 135,568,430 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	135,444,055 - 135,481,251 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	142,025,812 - 142,062,892 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	142,025,815 - 142,063,212 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	139,833,529 - 139,870,819 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	139,094,505 - 139,127,427 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	139,170,941 - 139,203,864 (-)	NCBI
Celera	7	127,985,198 - 128,017,825 (-)	NCBI		Celera
Cytogenetic Map	7	q36	NCBI

SLC11A2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	3,788,785 - 3,823,852 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	3,787,855 - 3,822,672 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	42,433,184 - 42,468,214 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	3,835,730 - 3,870,717 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	3,835,750 - 3,870,711 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	3,802,428 - 3,837,405 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	3,789,782 - 3,824,709 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	42,829,654 - 42,864,682 (-)	NCBI		UU_Cfam_GSD_1.0

Slc11a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	64,541,218 - 64,575,407 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936512	8,586,262 - 8,623,597 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936512	8,590,302 - 8,622,121 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC11A2
(Sus scrofa - pig)

No map positions available.

SLC11A2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	47,190,138 - 47,238,543 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	47,197,168 - 47,235,130 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	198,862,999 - 198,915,680 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc11a2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624816	1,345,006 - 1,384,299 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624816	1,345,020 - 1,389,615 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003825872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008951243	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008951244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008951247	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008951248	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034935849	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034935850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095646	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095647	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095649	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095650	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095651	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095653	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000053986 ⟹ ENSPPAP00000031122

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,629,686 - 38,668,861 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000053987 ⟹ ENSPPAP00000031123

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,631,483 - 38,669,241 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000053992 ⟹ ENSPPAP00000031128

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,631,646 - 38,677,377 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000053997 ⟹ ENSPPAP00000031133

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,646,864 - 38,668,861 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000054003 ⟹ ENSPPAP00000031139

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,647,000 - 38,651,684 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000054006 ⟹ ENSPPAP00000031142

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	38,648,589 - 38,668,861 (+)	Ensembl

RefSeq Acc Id:

XM_003825872 ⟹ XP_003825920

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,160,550 - 43,207,136 (+)	NCBI
NHGRI_mPanPan1	12	43,157,312 - 43,203,898 (+)	NCBI
Mhudiblu_PPA_v0	12	37,727,977 - 37,774,554 (+)	NCBI
PanPan1.1	12	38,631,483 - 38,677,377 (+)	NCBI

Sequence:

show sequence

ATCGCGGGGAGGGGAGGGCGTTAGCCAGCTTGGCGCTGGCTCCCGGAATATGGAGCCCTGGGCG
CGGGGGCGGCGTGTCAGGTGGTTGCCGAGCTGAATCATATTCTAAGAACTCAGCCACTCAGGTA
TCCACCATGGTGCTGGGTCCTGAACAGAAGATGTCAGATGACAGTGTTTCTGGAGATCATGGGG
AGTCTGCCAGTCTTGGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTCCACAGTCCCCTGG
GGACTCAGAGGAGTACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGTAC
TCTTGTTTTAGCTTTCGTAAACTCTGGGCTTTCACCGGACCAGGTTTTCTTATGAGCATTGCCT
ACCTGGATCCAGGAAATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCTGGATTTAAGTTGCT
CTGGATCCTTCTGTTGGCCACCCTTGTGGGGCTGCTGCTCCAGCGGCTTGCAGCTAGACTGGGA
GTGGTTACTGGGCTGCATCTTGCTGAAGTATGTCACCGTCAGTATCCCAAGGTCCCACGAGTCA
TCCTGTGGCTGATGGTGGAGTTGGCTATCATCGGCTCAGACATGCAAGAAGTCATTGGCTCAGC
CATTGCTATCAATCTTCTGTCTGTAGGAAGAATTCCTCTGTGGGGTGGCGTTCTCATCACCATT
GCAGATACTTTTGTATTTCTCTTCTTGGACAAATATGGCTTGCGGAAGCTAGAAGCATTTTTTG
GCTTTCTCATCACTATTATGGCCCTCACATTTGGATATGAGTATGTTACAGTGAAACCCAGCCA
GAGCCAGGTACTCAAGGGCATGTTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGAA
CAGGCTGTGGGTATCGTGGGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAG
TCAAGTCTAGACAGGTAAACCGGAACAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTT
CATTGAATCCTGCATTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGTTGTCTCAGTCTTT
GCTGAAGCATTTTTTGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTC
CTCATGCTGGCCTCTTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGTGT
TGTGCTGGGATGTTACTTTGGGCCTGCTGCACTCTACATTTGGGCAGTGGGGATCCTGGCTGCA
GGACAGAGCTCCACCATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGGGATTCCTGAACC
TAAAGTGGTCACGCTTTGCCCGAGTGGTTCTGACTCGCTCTATTGCCATCATCCCCACTCTGCT
TGTTGCTGTCTTCCAAGATGTAGAGCATCTAACAGGGATGAATGACTTTCTGAATGTTCTACAG
AGCTTACAGCTTCCCTTTGCTCTCATACCCATCCTCACATTTACGAGCTTGCGGCCAGTAATGA
GTGACTTTGCCAATGGACTAGGCTGGCGGATTGCAGGAGGAATCTTGGTCCTTATAATCTGTTC
CATCAATATGTACTTTGTGGTGGTTTATGTCCGGGACCTAGGGCATGTGGCATTATATGTGGTG
GCTGCTGTGGTCAGCGTGGCTTATCTGGGCTTTGTGTTCTACTTGGGTTGGCAATGTTTGATTG
CACTGGGCATGTCCTTCCTGGACTGTGGGCATACGTGCCATCTGGGATTGACAGCTCAGCCTGA
ACTCTATCTTCTGAACACCATGGACGCTGACTCACTTGTGTCTAGATGACTGACAGCCTGAGAG
ACTCTATAAGAACATGTTTTTCTAAGCCCTTTTTGTGCCAGGTGTCCTGTTAACATCTCTGTTA
GTTCAGAGGTGAGTTTTGTTCAGACGTTTTGAACAAAAGGCAAAGATTTCCTCATGGGAAGGGT
GTTCAAAACTGACAGCTATAAATGTAGGTCAGAGACCCACCCACCTCATAACAGTCATACACTC
CCAGAGTTAAACGATTGGCCTCTGATGGCCACACACCCCTATGGGCTTGTGTCTTGGACTCTGG
GATTTAAAAGATATATATGTATATATATTTATGTAAACCTGAGCATCTCAGTTTGGGTAGAGTT
TTAAGGTTATATGAAACTGATAGAACTTTTGTATTTTTTTTTAAAATATTGTTTTGATATATCA
GATATTTGTTTTGTCTGGATCACAAGTGAGAAAGAAAAGAGAATAATGCTCTTTTTCACAATGA
ACTGGTCAAATTGACTATCTTGTAAAGTGATACTTTACTATGTCAGTGAAATTTCAGTTTGATT
TTAGTCAACCAGATTATATCCTTTGTATCTACTGATATTAACACATCATTTCTTAAAAAAAACA
TTTCTTCTGTTTGGCAATCATAATTAACTCTGGTTATCAGCCTATTTTGTAATTATTGTCTTTG
TCGTCACTTTTCTTGAATTATTTTCTAGTCATTAAACAGATATGAAGGCATTGCCAAAGAGCTT
TAATACCCAGTAACAAGATCCAGAAACCACACTTTAACCAGTGATCAGTTTTCCGTGCTGCATT
GTAACTCAGCTCATTCTGGCATTCAAGTTTTAGGCAAAAAAAGAGGAAACTTCTAACATTTAGC
TTGTAAGTCCTGACATAAGATAGTGAAGATATTTATCTTCTTTCTAATATTTGTATAGTCCGCC
AATGTATTTTCTTCCCACTATTCCCATTAACATACCAAACACTGTTTCTAGGTCCAAAGTCTAT
TTCTAGGAGTGGCCAATATTTGTATTGTTGAATCTCCTAGGGAATGCTAAATGTTTCACTTTAA
AATACCTATTTATACCAAGTAGCATGAGATTAGTACTAGAGTGAGATTTGGAAGATTAGTCCAC
ATAACACAAACTGCTTGCCTACATGTATAGATTTTTTTTTCACCCACCTTCCTAACCAGGAATT
TGTTTCCTTAAATTTTTTTTTTGTTGTTGTTGTTGTTTGTTGTTATTTTTTTGAGAAGAGTCTT
GCCCTGTCGCCAAGGCGGGAATGCATTGACGTGATCTCAGTTCACTGTAACCTCTGCCTCCCGG
GTTTAATCGATTCTCCTCCTTCAGCCTCCTGAATAGCTGGGATTACAGGCACCACATTTTTAGT
GGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCTTGACCTCAAGTGATCTACCT
GCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCCAGCATTTTTTTGTTG
TTAAGACAGGGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCA
ACTTCTGCCACCTGGGCTTAAGCCATCCTCCCACTTCAGCATCCCAAATAGCTGGGACTGCAGG
CATACACCACCACACCCAGCTAATTTTTGTATTTTTTGTAGAGACGGGAATTTCACCATGTTGC
CCAGGCTGGTCTTGAACTCATGAGCTCAAGTAATCTGCTGGCCTTGGCCTCCCAAAGTGCTGAG
ATTATAGGCGTGAGCCACTGCATCCAGCTCACTCCTCATTTCTTTCTAGCCCCAAAGGTGTTGA
GTCAGCAAATCCTGCAGCCTTTGTGTGACTTTGAGCATCACTTTCCCCTTTCAGCATTAAATAT
ATGACCTCTCTGCCTTATTTTAGAACTTACTACATTTCAATAAAACTTTTTTAAAAATCCA

hide sequence

RefSeq Acc Id:

XM_008951247 ⟹ XP_008949495

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,176,517 - 43,207,136 (+)	NCBI
NHGRI_mPanPan1	12	43,174,453 - 43,203,898 (+)	NCBI
Mhudiblu_PPA_v0	12	37,745,116 - 37,774,554 (+)	NCBI
PanPan1.1	12	38,648,457 - 38,676,150 (+)	NCBI

Sequence:

show sequence

ACTTTACTGCAAGCCTTAGTCAGAGTACAAAGGGTTCCTGCTTGGTGGTTTTGCTGCAGCTTCA
GAGTTTAGCCTGAACTGTGGCAGGATTTTGTAACTTGCACATTTTTTGAGAAGTCTGATGGAGG
TATAATGTCCACGGTCGATTCTTTGAACAGTGTTTCTGGAGATCATGGGGAGTCTGCCAGTCTT
GGTAACATCAACCCTGCCTATAGTAATCCCTCTCTTCCACAGTCCCCTGGGGACTCAGAGGAGT
ACTTCGCCACTTACTTTAATGAGAAGATCTCCATTCCTGAGGAGGAGTACTCTTGTTTTAGCTT
TCGTAAACTCTGGGCTTTCACCGGACCAGGTTTTCTTATGAGCATTGCCTACCTGGATCCAGGA
AATATTGAATCCGATTTGCAGTCTGGAGCAGTGGCTGGATTTAAGTTGCTCTGGATCCTTCTGT
TGGCCACCCTTGTGGGGCTGCTGCTCCAGCGGCTTGCAGCTAGACTGGGAGTGGTTACTGGGCT
GCATCTTGCTGAAGTATGTCACCGTCAGTATCCCAAGGTCCCACGAGTCATCCTGTGGCTGATG
GTGGAGTTGGCTATCATCGGCTCAGACATGCAAGAAGTCATTGGCTCAGCCATTGCTATCAATC
TTCTGTCTGTAGGAAGAATTCCTCTGTGGGGTGGCGTTCTCATCACCATTGCAGATACTTTTGT
ATTTCTCTTCTTGGACAAATATGGCTTGCGGAAGCTAGAAGCATTTTTTGGCTTTCTCATCACT
ATTATGGCCCTCACATTTGGATATGAGTATGTTACAGTGAAACCCAGCCAGAGCCAGGTACTCA
AGGGCATGTTCGTACCATCCTGTTCAGGCTGTCGCACTCCACAGATTGAACAGGCTGTGGGTAT
CGTGGGAGCTGTCATCATGCCACACAACATGTACCTGCATTCTGCCTTAGTCAAGTCTAGACAG
GTAAACCGGAACAATAAGCAGGAAGTTCGAGAAGCCAATAAGTACTTTTTCATTGAATCCTGCA
TTGCACTCTTTGTTTCCTTCATCATCAATGTCTTTGTTGTCTCAGTCTTTGCTGAAGCATTTTT
TGGGAAAACCAACGAGCAGGTGGTTGAAGTCTGTACAAATACCAGCAGTCCTCATGCTGGCCTC
TTTCCTAAAGATAACTCGACACTGGCTGTGGACATCTACAAAGGGGGTGTTGTGCTGGGATGTT
ACTTTGGGCCTGCTGCACTCTACATTTGGGCAGTGGGGATCCTGGCTGCAGGACAGAGCTCCAC
CATGACAGGAACCTATTCTGGCCAGTTTGTCATGGAGGGATTCCTGAACCTAAAGTGGTCACGC
TTTGCCCGAGTGGTTCTGACTCGCTCTATTGCCATCATCCCCACTCTGCTTGTTGCTGTCTTCC
AAGATGTAGAGCATCTAACAGGGATGAATGACTTTCTGAATGTTCTACAGAGCTTACAGCTTCC
CTTTGCTCTCATACCCATCCTCACATTTACGAGCTTGCGGCCAGTAATGAGTGACTTTGCCAAT
GGACTAGGCTGGCGGATTGCAGGAGGAATCTTGGTCCTTATAATCTGTTCCATCAATATGTACT
TTGTGGTGGTTTATGTCCGGGACCTAGGGCATGTGGCATTATATGTGGTGGCTGCTGTGGTCAG
CGTGGCTTATCTGGGCTTTGTGTTCTACTTGGGTTGGCAATGTTTGATTGCACTGGGCATGTCC
TTCCTGGACTGTGGGCATACGTGCCATCTGGGATTGACAGCTCAGCCTGAACTCTATCTTCTGA
ACACCATGGACGCTGACTCACTTGTGTCTAGATGACTGACAGCCTGAGAGACTCTATAAGAACA
TGTTTTTCTAAGCCCTTTTTGTGCCAGGTGTCCTGTTAACATCTCTGTTAGTTCAGAGGTGAGT
TTTGTTCAGACGTTTTGAACAAAAGGCAAAGATTTCCTCATGGGAAGGGTGTTCAAAACTGACA
GCTATAAATGTAGGTCAGAGACCCACCCACCTCATAACAGTCATACACTCCCAGAGTTAAACGA
TTGGCCTCTGATGGCCACACACCCCTATGGGCTTGTGTCTTGGACTCTGGGATTTAAAAGATAT
ATATGTATATATATTTATGTAAACCTGAGCATCTCAGTTTGGGTAGAGTTTTAAGGTTATATGA
AACTGATAGAACTTTTGTATTTTTTTTTAAAATATTGTTTTGATATATCAGATATTTGTTTTGT
CTGGATCACAAGTGAGAAAGAAAAGAGAATAATGCTCTTTTTCACAATGAACTGGTCAAATTGA
CTATCTTGTAAAGTGATACTTTACTATGTCAGTGAAATTTCAGTTTGATTTTAGTCAACCAGAT
TATATCCTTTGTATCTACTGATATTAACACATCATTTCTTAAAAAAAACATTTCTTCTGTTTGG
CAATCATAATTAACTCTGGTTATCAGCCTATTTTGTAATTATTGTCTTTGTCGTCACTTTTCTT
GAATTATTTTCTAGTCATTAAACAGATATGAAGGCA

hide sequence

RefSeq Acc Id:

XM_055095646 ⟹ XP_054951621

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,160,561 - 43,204,429 (+)	NCBI
NHGRI_mPanPan1	12	43,157,328 - 43,201,185 (+)	NCBI

RefSeq Acc Id:

XM_055095647 ⟹ XP_054951622

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,160,554 - 43,204,429 (+)	NCBI
NHGRI_mPanPan1	12	43,157,316 - 43,201,185 (+)	NCBI

RefSeq Acc Id:

XM_055095648 ⟹ XP_054951623

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,160,710 - 43,204,429 (+)	NCBI
NHGRI_mPanPan1	12	43,157,471 - 43,201,186 (+)	NCBI

RefSeq Acc Id:

XM_055095649 ⟹ XP_054951624

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,169,974 - 43,204,429 (+)	NCBI
NHGRI_mPanPan1	12	43,166,786 - 43,201,186 (+)	NCBI

RefSeq Acc Id:

XM_055095650 ⟹ XP_054951625

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,176,511 - 43,204,430 (+)	NCBI
NHGRI_mPanPan1	12	43,174,453 - 43,201,187 (+)	NCBI

RefSeq Acc Id:

XM_055095651 ⟹ XP_054951626

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,169,974 - 43,207,136 (+)	NCBI
NHGRI_mPanPan1	12	43,166,736 - 43,203,898 (+)	NCBI

RefSeq Acc Id:

XM_055095653 ⟹ XP_054951628

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	43,160,561 - 43,205,260 (+)	NCBI
NHGRI_mPanPan1	12	43,157,328 - 43,203,898 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_003825920	(Get FASTA)	NCBI Sequence Viewer
	XP_008949495	(Get FASTA)	NCBI Sequence Viewer
	XP_054951621	(Get FASTA)	NCBI Sequence Viewer
	XP_054951622	(Get FASTA)	NCBI Sequence Viewer
	XP_054951623	(Get FASTA)	NCBI Sequence Viewer
	XP_054951624	(Get FASTA)	NCBI Sequence Viewer
	XP_054951625	(Get FASTA)	NCBI Sequence Viewer
	XP_054951626	(Get FASTA)	NCBI Sequence Viewer
	XP_054951628	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000031122.1
	ENSPPAP00000031123.1
	ENSPPAP00000031128.1
	ENSPPAP00000031133.1
	ENSPPAP00000031139.1
	ENSPPAP00000031142.1

RefSeq Acc Id:	XP_003825920 ⟸ XM_003825872
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLPQSPGDSEEYFATYFNEKISIPEEEYSC FSFRKLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVV TGLHLAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIAD TFVFLFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQA VGIVGAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAE AFFGKTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQ SSTMTGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSL QLPFALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHVALYVVAA VVSVAYLGFVFYLGWQCLIALGMSFLDCGHTCHLGLTAQPELYLLNTMDADSLVSR hide sequence

RefSeq Acc Id:	XP_008949495 ⟸ XM_008951247
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSTVDSLNSVSGDHGESASLGNINPAYSNPSLPQSPGDSEEYFATYFNEKISIPEEEYSCFSFR KLWAFTGPGFLMSIAYLDPGNIESDLQSGAVAGFKLLWILLLATLVGLLLQRLAARLGVVTGLH LAEVCHRQYPKVPRVILWLMVELAIIGSDMQEVIGSAIAINLLSVGRIPLWGGVLITIADTFVF LFLDKYGLRKLEAFFGFLITIMALTFGYEYVTVKPSQSQVLKGMFVPSCSGCRTPQIEQAVGIV GAVIMPHNMYLHSALVKSRQVNRNNKQEVREANKYFFIESCIALFVSFIINVFVVSVFAEAFFG KTNEQVVEVCTNTSSPHAGLFPKDNSTLAVDIYKGGVVLGCYFGPAALYIWAVGILAAGQSSTM TGTYSGQFVMEGFLNLKWSRFARVVLTRSIAIIPTLLVAVFQDVEHLTGMNDFLNVLQSLQLPF ALIPILTFTSLRPVMSDFANGLGWRIAGGILVLIICSINMYFVVVYVRDLGHVALYVVAAVVSV AYLGFVFYLGWQCLIALGMSFLDCGHTCHLGLTAQPELYLLNTMDADSLVSR hide sequence

RefSeq Acc Id:

ENSPPAP00000031142 ⟸ ENSPPAT00000054006

RefSeq Acc Id:

ENSPPAP00000031139 ⟸ ENSPPAT00000054003

RefSeq Acc Id:

ENSPPAP00000031133 ⟸ ENSPPAT00000053997

RefSeq Acc Id:

ENSPPAP00000031128 ⟸ ENSPPAT00000053992

RefSeq Acc Id:

ENSPPAP00000031122 ⟸ ENSPPAT00000053986

RefSeq Acc Id:

ENSPPAP00000031123 ⟸ ENSPPAT00000053987

RefSeq Acc Id:	XP_054951622 ⟸ XM_055095647
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951628 ⟸ XM_055095653
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951621 ⟸ XM_055095646
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951623 ⟸ XM_055095648
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951626 ⟸ XM_055095651
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951624 ⟸ XM_055095649
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951625 ⟸ XM_055095650
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9BXB1 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000038498	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000053986.1	UniProtKB/TrEMBL
	ENSPPAT00000053987.1	UniProtKB/TrEMBL
	ENSPPAT00000053992.1	UniProtKB/TrEMBL
	ENSPPAT00000053997.1	UniProtKB/TrEMBL
	ENSPPAT00000054003.1	UniProtKB/TrEMBL
	ENSPPAT00000054006.1	UniProtKB/TrEMBL
InterPro	NRAMP_fam	UniProtKB/TrEMBL
KEGG Report	pps:100985494	UniProtKB/TrEMBL
NCBI Gene	SLC11A2	ENTREZGENE
PANTHER	NATURAL RESISTANCE-ASSOCIATED MACROPHAGE PROTEIN 2	UniProtKB/TrEMBL
	PROTEIN GVQW1-RELATED	UniProtKB/TrEMBL
	PTHR11706	UniProtKB/TrEMBL
Pfam	Nramp	UniProtKB/TrEMBL
PRINTS	F138DOMAIN	UniProtKB/TrEMBL
	NATRESASSCMP	UniProtKB/TrEMBL
UniProt	A0A2R9BP19_PANPA	UniProtKB/TrEMBL
	A0A2R9BRR9_PANPA	UniProtKB/TrEMBL
	A0A2R9BRS5_PANPA	UniProtKB/TrEMBL
	A0A2R9BRT1_PANPA	UniProtKB/TrEMBL
	A0A2R9BX91_PANPA	UniProtKB/TrEMBL
	A0A2R9BXB1	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)