FNDC8 (fibronectin type III domain containing 8) - Rat Genome Database

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Gene: FNDC8 (fibronectin type III domain containing 8) Pan paniscus
Analyze
Symbol: FNDC8
Name: fibronectin type III domain containing 8
RGD ID: 11943909
Description: ASSOCIATED WITH genetic disease (ortholog); hereditary breast ovarian cancer syndrome (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fibronectin type III domain-containing protein 8
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21929,334,255 - 29,346,016 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11731,215,227 - 31,226,962 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,655,487 - 21,665,633 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,947,380 - 21,956,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,947,380 - 21,956,499 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FNDC8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21929,334,255 - 29,346,016 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11731,215,227 - 31,226,962 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01721,655,487 - 21,665,633 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11721,947,380 - 21,956,499 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1721,947,380 - 21,956,499 (-)Ensemblpanpan1.1panPan2
FNDC8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381735,121,615 - 35,130,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1735,121,615 - 35,130,732 (+)EnsemblGRCh38hg38GRCh38
GRCh371733,448,634 - 33,457,751 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361730,472,744 - 30,481,864 (+)NCBINCBI36Build 36hg18NCBI36
Celera1730,358,824 - 30,367,943 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1729,633,318 - 29,642,432 (+)NCBIHuRef
CHM1_11733,512,993 - 33,522,110 (+)NCBICHM1_1
T2T-CHM13v2.01736,069,529 - 36,078,645 (+)NCBIT2T-CHM13v2.0
Fndc8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391182,782,971 - 82,791,563 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1182,782,950 - 82,791,627 (+)EnsemblGRCm39 Ensembl
GRCm381182,892,145 - 82,900,737 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1182,892,124 - 82,900,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv371182,705,647 - 82,714,239 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361182,708,319 - 82,716,996 (+)NCBIMGSCv36mm8
Celera1192,511,195 - 92,519,852 (+)NCBICelera
Cytogenetic Map11CNCBI
cM Map1150.3NCBI
Fndc8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81068,323,500 - 68,331,638 (+)NCBIGRCr8
mRatBN7.21067,825,952 - 67,834,090 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1067,825,952 - 67,834,090 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1072,445,992 - 72,454,130 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01071,951,373 - 71,959,511 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01067,415,477 - 67,423,603 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01070,242,852 - 70,250,990 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1070,242,874 - 70,250,934 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01069,874,015 - 69,882,153 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,109,016 - 71,117,154 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11071,122,706 - 71,129,721 (+)NCBI
Celera1066,770,188 - 66,778,326 (+)NCBICelera
Cytogenetic Map10q26NCBI
Fndc8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554819,812,156 - 9,819,865 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554819,812,402 - 9,820,070 (+)NCBIChiLan1.0ChiLan1.0
FNDC8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1938,232,116 - 38,240,791 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl938,232,117 - 38,240,791 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha937,456,092 - 37,464,981 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0939,044,045 - 39,052,943 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl939,044,046 - 39,052,888 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1937,827,609 - 37,836,517 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0938,113,127 - 38,122,029 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0938,200,661 - 38,209,559 (-)NCBIUU_Cfam_GSD_1.0
Fndc8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560237,232,976 - 37,240,130 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936538111,241 - 117,961 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936538110,569 - 117,961 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FNDC8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,045,094 - 40,052,597 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,045,721 - 40,052,637 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21241,556,921 - 41,563,844 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FNDC8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11628,624,441 - 28,633,723 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1628,624,735 - 28,633,537 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660751,353,489 - 1,363,002 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fndc8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248752,989,359 - 2,996,183 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248752,989,290 - 2,996,406 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000032169   ⟹   ENSPPAP00000009526
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1721,947,380 - 21,956,499 (-)Ensembl
RefSeq Acc Id: XM_003817992   ⟹   XP_003818040
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21929,334,255 - 29,346,016 (-)NCBI
NHGRI_mPanPan11731,215,227 - 31,226,962 (-)NCBI
Mhudiblu_PPA_v01721,655,487 - 21,665,633 (-)NCBI
PanPan1.11721,947,380 - 21,956,499 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034942087   ⟹   XP_034797978
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21929,335,474 - 29,346,016 (-)NCBI
NHGRI_mPanPan11731,216,446 - 31,226,962 (-)NCBI
Mhudiblu_PPA_v01721,655,495 - 21,665,633 (-)NCBI
RefSeq Acc Id: XR_008621612
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21929,334,255 - 29,346,016 (-)NCBI
NHGRI_mPanPan11731,215,227 - 31,226,962 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003818040 (Get FASTA)   NCBI Sequence Viewer  
  XP_034797978 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000009526
  ENSPPAP00000009526.1
RefSeq Acc Id: XP_003818040   ⟸   XM_003817992
- Peptide Label: isoform X1
- UniProtKB: A0A2R8ZX21 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034797978   ⟸   XM_034942087
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000009526   ⟸   ENSPPAT00000032169
Protein Domains
Fibronectin type-III


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027994 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000032169.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
KEGG Report pps:100975554 UniProtKB/TrEMBL
NCBI Gene FNDC8 ENTREZGENE
PANTHER FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
  FIBRONECTIN TYPE III DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/TrEMBL
UniProt A0A2R8ZX21 ENTREZGENE, UniProtKB/TrEMBL