HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3) - Rat Genome Database

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Gene: HSD17B3 (hydroxysteroid 17-beta dehydrogenase 3) Pan paniscus
Analyze
Symbol: HSD17B3
Name: hydroxysteroid 17-beta dehydrogenase 3
RGD ID: 11932133
Description: ENCODES a protein that exhibits estradiol 17-beta-dehydrogenase [NAD(P)] activity (ortholog); testosterone dehydrogenase (NAD+) activity (ortholog); INVOLVED IN biphenyl metabolic process (ortholog); cellular response to antibiotic (ortholog); cellular response to gonadotropin stimulus (ortholog); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; ASSOCIATED WITH 17-beta hydroxysteroid dehydrogenase 3 deficiency (ortholog); Alzheimer's disease (ortholog); disorder of sexual development (ortholog); FOUND IN endoplasmic reticulum (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 17-beta-hydroxysteroid dehydrogenase type 3; testosterone 17-beta-dehydrogenase 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21143,148,097 - 43,220,957 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1943,150,475 - 43,223,335 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0967,327,047 - 67,411,754 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1995,451,031 - 95,531,578 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl995,451,031 - 95,522,739 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
HSD17B3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21143,148,097 - 43,220,957 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1943,150,475 - 43,223,335 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0967,327,047 - 67,411,754 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1995,451,031 - 95,531,578 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl995,451,031 - 95,522,739 (-)Ensemblpanpan1.1panPan2
HSD17B3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38996,235,306 - 96,302,176 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl996,235,306 - 96,302,176 (-)EnsemblGRCh38hg38GRCh38
GRCh37998,997,588 - 99,064,458 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,037,410 - 98,104,255 (-)NCBINCBI36Build 36hg18NCBI36
Build 34996,077,143 - 96,143,989NCBI
Celera969,439,150 - 69,506,013 (-)NCBICelera
Cytogenetic Map9q22.32NCBI
HuRef968,608,833 - 68,675,720 (-)NCBIHuRef
CHM1_1999,144,095 - 99,210,909 (-)NCBICHM1_1
T2T-CHM13v2.09108,406,656 - 108,473,885 (-)NCBIT2T-CHM13v2.0
Hsd17b3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,206,088 - 64,237,076 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1364,206,080 - 64,237,044 (-)EnsemblGRCm39 Ensembl
GRCm381364,058,274 - 64,089,262 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,058,266 - 64,089,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,159,582 - 64,190,509 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361364,067,496 - 64,098,408 (-)NCBIMGSCv36mm8
Celera1365,722,306 - 65,753,080 (-)NCBICelera
Cytogenetic Map13B3NCBI
cM Map1333.26NCBI
Hsd17b3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8171,032,958 - 1,064,283 (+)NCBIGRCr8
mRatBN7.2171,027,229 - 1,058,554 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl171,027,229 - 1,058,554 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx171,045,909 - 1,077,225 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0172,588,485 - 2,619,812 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0171,043,327 - 1,074,653 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0171,579,319 - 1,610,745 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,579,319 - 1,610,745 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,570,077 - 1,600,357 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,554,164 - 6,585,525 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,554,163 - 6,585,525 (+)NCBI
Celera171,458,596 - 1,490,020 (-)NCBICelera
Cytogenetic Map17p14NCBI
Hsd17b3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542223,101,795 - 23,148,999 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542223,104,752 - 23,251,250 (-)NCBIChiLan1.0ChiLan1.0
HSD17B3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,551,013 - 70,586,364 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,487,334 - 70,586,368 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha171,314,005 - 71,349,356 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0170,851,728 - 70,887,109 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl170,788,086 - 70,886,492 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1170,663,395 - 70,698,690 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0170,426,654 - 70,461,997 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0171,137,784 - 71,173,174 (+)NCBIUU_Cfam_GSD_1.0
Hsd17b3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049446,011,845 - 6,041,225 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936487228,557 - 245,295 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936487228,301 - 282,495 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSD17B3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1025,822,913 - 25,866,871 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11025,822,913 - 25,866,871 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21029,949,458 - 29,993,351 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSD17B3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,831,807 - 106,885,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl12106,832,034 - 106,886,385 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603895,260,015 - 95,282,321 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hsd17b3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475317,789,789 - 17,832,747 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475317,770,326 - 17,832,560 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000057789   ⟹   ENSPPAP00000034904
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl995,451,031 - 95,522,739 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057791   ⟹   ENSPPAP00000034906
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl995,451,031 - 95,522,739 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057793   ⟹   ENSPPAP00000034908
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl995,460,070 - 95,522,518 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057795   ⟹   ENSPPAP00000034910
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl995,460,070 - 95,522,518 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000057800   ⟹   ENSPPAP00000034915
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl995,466,227 - 95,522,518 (-)Ensembl
RefSeq Acc Id: XM_034967812   ⟹   XP_034823703
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21143,148,097 - 43,220,957 (+)NCBI
NHGRI_mPanPan1943,150,475 - 43,223,335 (+)NCBI
Mhudiblu_PPA_v0967,327,047 - 67,411,752 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034823703 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034904.1
  ENSPPAP00000034906.1
  ENSPPAP00000034908.1
  ENSPPAP00000034910.1
  ENSPPAP00000034915.1
Reference Protein Sequences
RefSeq Acc Id: XP_034823703   ⟸   XM_034967812
- UniProtKB: A0A2R9C906 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000034908   ⟸   ENSPPAT00000057793
RefSeq Acc Id: ENSPPAP00000034906   ⟸   ENSPPAT00000057791
RefSeq Acc Id: ENSPPAP00000034910   ⟸   ENSPPAT00000057795
RefSeq Acc Id: ENSPPAP00000034904   ⟸   ENSPPAT00000057789
RefSeq Acc Id: ENSPPAP00000034915   ⟸   ENSPPAT00000057800


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040278 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057789.1 UniProtKB/TrEMBL
  ENSPPAT00000057791.1 UniProtKB/TrEMBL
  ENSPPAT00000057793.1 UniProtKB/TrEMBL
  ENSPPAT00000057795.1 UniProtKB/TrEMBL
  ENSPPAT00000057800.1 UniProtKB/TrEMBL
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/TrEMBL
InterPro NAD(P)-bd_dom_sf UniProtKB/TrEMBL
  Sc_DH/Rdtase_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/TrEMBL
NCBI Gene HSD17B3 ENTREZGENE
PANTHER PTHR43899:SF7 UniProtKB/TrEMBL
  RH59310P UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
PIRSF 11-beta-HSD1 UniProtKB/TrEMBL
PRINTS GDHRDH UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/TrEMBL
PROSITE ADH_SHORT UniProtKB/TrEMBL
Superfamily-SCOP SSF51735 UniProtKB/TrEMBL
UniProt A0A2R9BZ05_PANPA UniProtKB/TrEMBL
  A0A2R9BZK5_PANPA UniProtKB/TrEMBL
  A0A2R9C291_PANPA UniProtKB/TrEMBL
  A0A2R9C296_PANPA UniProtKB/TrEMBL
  A0A2R9C906 ENTREZGENE, UniProtKB/TrEMBL