CDK1 (cyclin dependent kinase 1) - Rat Genome Database

Name: CDK1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: CDK1 (cyclin dependent kinase 1) Pan paniscus

Analyze

Symbol:

CDK1

Name:

cyclin dependent kinase 1

RGD ID:

11927757

Description:

ENCODES a protein that exhibits cyclin binding (ortholog); histone kinase activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to hydrogen peroxide (ortholog); cellular response to organic cyclic compound (ortholog); ASSOCIATED WITH Autosomal Dominant Intellectual Developmental Disorder 70 (ortholog); breast cancer (ortholog); cervical cancer (ortholog); FOUND IN cyclin B1-CDK1 complex (ortholog); cytoplasm (ortholog); endoplasmic reticulum exit site (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cyclin-dependent kinase 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	72,992,580 - 73,009,108 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	72,997,903 - 73,014,430 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	57,314,692 - 57,331,261 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	59,647,993 - 59,664,434 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	59,647,993 - 59,664,434 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Autosomal Dominant Intellectual Developmental Disorder 70 (ISO)

breast cancer (ISO)

cervical cancer (ISO)

COVID-19 (ISO)

diffuse large B-cell lymphoma (ISO)

Experimental Liver Cirrhosis (ISO)

gallbladder adenocarcinoma (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Prostatic Neoplasms (ISO)

Spinal Cord Injuries (ISO)

Thyroid Neoplasms (ISO)

transitional cell carcinoma (ISO)

urinary bladder cancer (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (ISO)

cell division (IEA)

cellular response to hydrogen peroxide (ISO)

cellular response to organic cyclic compound (ISO)

chromatin remodeling (IEA)

chromosome condensation (ISO)

DNA damage response (ISO)

epithelial cell differentiation (IEA)

fibroblast proliferation (IEA,ISO)

G2/M transition of mitotic cell cycle (IEA)

Golgi disassembly (ISO)

meiotic cell cycle process involved in oocyte maturation (ISO)

meiotic spindle organization (ISO)

microtubule cytoskeleton organization involved in mitosis (IEA)

mitotic cell cycle phase transition (IEA,ISO)

mitotic G2 DNA damage checkpoint signaling (IEA,ISO)

mitotic nuclear membrane disassembly (IEA)

negative regulation of apoptotic process (IEA)

negative regulation of gene expression (ISO)

positive regulation of cardiac muscle cell proliferation (ISO)

positive regulation of DNA replication (ISO)

positive regulation of G2/M transition of mitotic cell cycle (IEA)

positive regulation of gene expression (ISO)

positive regulation of meiotic cell cycle process involved in oocyte maturation (ISO)

positive regulation of mitochondrial ATP synthesis coupled electron transport (IEA)

positive regulation of mitotic cell cycle (ISO)

positive regulation of mitotic sister chromatid segregation (IEA)

positive regulation of protein import into nucleus (ISO)

positive regulation of protein localization to nucleus (IEA)

protein localization to kinetochore (IEA)

protein-containing complex assembly (ISO)

regulation of attachment of mitotic spindle microtubules to kinetochore (ISO)

regulation of circadian rhythm (IEA)

regulation of transcription by RNA polymerase II (IEA)

response to activity (ISO)

response to amine (ISO)

response to axon injury (ISO)

response to cadmium ion (ISO)

response to copper ion (ISO)

response to ethanol (ISO)

response to hydrogen peroxide (ISO)

response to organic cyclic compound (ISO)

response to organonitrogen compound (ISO)

response to toxic substance (ISO)

response to xenobiotic stimulus (ISO)

ventricular cardiac muscle cell development (ISO)

Cellular Component

centrosome (IEA)

cyclin A2-CDK1 complex (IEA)

cyclin B1-CDK1 complex (IEA,ISO)

cyclin-dependent protein kinase holoenzyme complex (IEA)

cytoplasm (IEA,ISO)

cytosol (IEA)

endoplasmic reticulum exit site (ISO)

germinal vesicle (ISO)

midbody (IEA)

mitochondrial matrix (IEA)

mitotic spindle (IEA)

nucleoplasm (IEA)

nucleus (IEA,ISO)

spindle microtubule (IEA)

Molecular Function

ATP binding (IEA)

chromatin binding (IEA)

cyclin binding (IEA,ISO)

cyclin-dependent protein kinase activity (IEA)

cyclin-dependent protein serine/threonine kinase activity (IEA)

histone kinase activity (IEA,ISO)

Hsp70 protein binding (IEA)

kinase activity (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

RNA polymerase II CTD heptapeptide repeat kinase activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CDK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	72,992,580 - 73,009,108 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	72,997,903 - 73,014,430 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	57,314,692 - 57,331,261 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	59,647,993 - 59,664,434 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	59,647,993 - 59,664,434 (+)	Ensembl	panpan1.1		panPan2

CDK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	60,778,331 - 60,794,852 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	60,778,331 - 60,794,852 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	62,538,089 - 62,554,610 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	62,205,690 - 62,223,930 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	10	62,209,916 - 62,223,930	NCBI
Celera	10	55,803,740 - 55,820,255 (+)	NCBI		Celera
Cytogenetic Map	10	q21.2	NCBI
HuRef	10	56,527,463 - 56,544,301 (+)	NCBI		HuRef
CHM1_1	10	62,820,315 - 62,836,829 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	61,635,069 - 61,651,590 (+)	NCBI		T2T-CHM13v2.0

Cdk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	69,170,976 - 69,188,742 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	69,170,976 - 69,188,768 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	69,335,146 - 69,352,912 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	69,335,146 - 69,352,938 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	68,799,383 - 68,815,660 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	68,731,992 - 68,748,269 (-)	NCBI		MGSCv36	mm8
Celera	10	70,426,785 - 70,443,097 (-)	NCBI		Celera
Cytogenetic Map	10	B5.3	NCBI
cM Map	10	36.07	NCBI

Cdk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	19,265,252 - 19,280,456 (+)	NCBI		GRCr8
mRatBN7.2	20	19,266,226 - 19,281,417 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	19,266,248 - 19,281,408 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	20	19,995,212 - 20,010,375 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	19,347,690 - 19,362,853 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	19,822,895 - 19,838,058 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	20,576,341 - 20,591,510 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	20,576,377 - 20,591,549 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	22,694,883 - 22,709,860 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	20,018,044 - 20,044,030 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	20	20,031,843 - 20,057,830 (+)	NCBI
Celera	20	20,642,946 - 20,658,475 (+)	NCBI		Celera
RH 3.4 Map	20	252.37	RGD
Cytogenetic Map	20	p11	NCBI

Cdk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	14,210,680 - 14,226,474 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	14,210,681 - 14,226,474 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	12,884,106 - 12,899,203 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	12,883,385 - 12,899,197 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	13,089,613 - 13,104,900 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	13,149,444 - 13,169,783 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	13,148,851 - 13,178,179 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	13,127,253 - 13,147,585 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	13,245,048 - 13,265,394 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	13,555,896 - 13,576,243 (+)	NCBI		UU_Cfam_GSD_1.0

Cdk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	68,214,228 - 68,227,370 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936614	2,300,513 - 2,313,624 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936614	2,300,682 - 2,313,611 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	64,233,987 - 64,372,197 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	64,233,945 - 64,255,290 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	69,262,279 - 69,277,262 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	70,475,736 - 70,492,947 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	31,365,769 - 31,382,908 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624791	2,891,239 - 2,915,001 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003830331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008955812	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034930624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000057675 ⟹ ENSPPAP00000034790

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	59,647,993 - 59,664,434 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000057683 ⟹ ENSPPAP00000034798

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	59,649,708 - 59,661,728 (+)	Ensembl

RefSeq Acc Id:

XM_003830331 ⟹ XP_003830379

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	72,992,585 - 73,009,108 (+)	NCBI
NHGRI_mPanPan1	10	72,997,907 - 73,014,430 (+)	NCBI
Mhudiblu_PPA_v0	10	57,314,796 - 57,331,261 (+)	NCBI
PanPan1.1	10	59,647,993 - 59,664,434 (+)	NCBI

Sequence:

show sequence

TTTAGCGCGGTGAGTTTGAAACTGCTCGCACTTGGCTTCAAAGCTGGCTCTTGGAAGTTGAGTG
GAGAGCGACGCGGTTGTTGTAGCTGCCGCTGCGGCCGCCGCGGAATAATAAGCCAGGATCTACC
ATACCCATTGACTAACTATGGAAGATTATACCAAAATAGAGAAAATTGGAGAAGGTACCTATGG
AGTTGTGTATAAGGGTAGACACAAAACTACAGGTCAAGTGGTAGCCATGAAAAAAATCAGACTA
GAAAGTGAAGAGGAAGGGGTTCCTAGTACTGCAATTCGGGAAATTTCTCTATTAAAGGAACTTC
GTCATCCAAATATAGTCAGTCTTCAGGATGTGCTTATGCAGGATTCCAGGTTATATCTCATCTT
TGAGTTTCTTTCCATGGATCTGAAGAAATACTTGGATTCTATCCCTCCTGGTCAGTACATGGAT
TCTTCACTTGTTAAGAGTTATTTATACCAAATCCTACAGGGGATTGTGTTTTGTCACTCTAGAA
GAGTTCTTCACAGAGACTTAAAACCTCAAAATCTCTTGATTGATGACAAAGGAACAATTAAACT
GGCTGATTTTGGCCTTGCCAGAGCTTTTGGAATACCTATTAGAGTATATACACATGAGGTAGTA
ACACTCTGGTACAGATCTCCAGAAGTATTGCTGGGGTCAGCTCGTTACTCAACTCCAGTTGACA
TTTGGAGTATAGGCACCATATTTGCTGAACTAGCAACTAAGAAACCACTTTTCCATGGGGATTC
AGAAATTGATCAACTCTTCAGGATTTTCAGAGCTTTGGGCACTCCCAATAATGAAGTGTGGCCA
GAAGTGGAATCTTTACAGGACTATAAGAATACATTTCCCAAATGGAAACCAGGAAGCCTAGCAT
CCCATGTCAAAAACTTGGATGAAAATGGCTTGGATTTGCTCTCGAAAATGTTAATCTATGATCC
AGCCAAACGAATTTCTGGCAAAATGGCACTGAATCATCCATATTTTAATGATTTGGACAATCAG
ATTAAGAAGATGTAGCTTTCTGACAAAAAGTTTCCATATGTTATATCAACAGATAGTTGTGTTT
TTATTGTTAACTCTTGTCTATTTTTGTCTTATATATATTTCTTTGTTATCAAACTTCAGCTGTA
CTTCGTCTTCTAATTTCAAAAATATAACTTAAAAATGTAAATATTCTATTATGAATTTAAATAT
AATTCTGTAAATGTGTGTAGGTCTCACTGTAACAACTATTTGTTACTATAATAAAACTATAATA
TTGATGTCAGGAATCAGGAAAAAATTTGAGTTGGCTTAAATCATCTCAGTCCTTATGGCAGTTT
TATTTTCCTGTAGTTGGAACTACTAAAATTTAGGAAAATGCTAAGTTCAAGTTTCGTAATGCTT
TGAAGTATTTTTATGTTCTGAATGTTTAAATGTTCTCATCAGTTTCTTGCCATGTTGTTAACTA
TACAACCTGGCTAAAGATGAATATTTTTCTACTGGTATTTTAATTTTTGACCTAAATGTTTAAG
CATTCGGAATGAGAAAACTATACAGATTTGAGAAATGATGCTAAATTTATAGGAGTTTTCAGTA
ACTTAAAAAGCTAACATGAGAGCATGCCAAAATTTGCTAAGTCTTACAAAGATCAAGGGCTGTC
CGCAACAGGGAAGAACAGTTTTGAAAATTTATGAACTATCTTATTTTTAGGTAGGTTTTGAAAG
CTTTTTGTCTAAGTGAATTCTTATGCCTTGGTCAGAGTAATAACTGAAGGAGTTGCTTGTCTTG
GCTTTCGAGTCTCAGTTTAAAACTACACATTTTGACAGTGTTTATTAGTAGCCATCTAAAAAGG
CTCTAATGTATATTTAACTAAAATTACTAGCTTTGGGAATTAAACTGTTTAACGAATAA

hide sequence

RefSeq Acc Id:

XM_008955812 ⟹ XP_008954060

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	72,992,580 - 73,009,108 (+)	NCBI
NHGRI_mPanPan1	10	72,997,903 - 73,014,430 (+)	NCBI
Mhudiblu_PPA_v0	10	57,314,796 - 57,331,261 (+)	NCBI
PanPan1.1	10	59,647,999 - 59,664,434 (+)	NCBI

Sequence:

show sequence

GCGGTGAGTTTGAAACTGCTCGCACTTGGCTTCAAAGCTGGCTCTTGGAAGTTGAGTGGAGAGC
GACGCGGTTGTTGTAGCTGCCGCTGCGGCCGCCGCGGAATAATAAGCCAGGATCTACCATACCC
ATTGACTAACTATGGAAGATTATACCAAAATAGAGAAAATTGGAGAAGGAATGTTTAGATCTAT
ATATGGCACAAATGAGGGGTATATCCCTTCGCCTGTTCCTCGACTCCAGCAGAACATTCTCGAT
TCTCCAGGTACCTATGGAGTTGTGTATAAGGGTAGACACAAAACTACAGGTCAAGTGGTAGCCA
TGAAAAAAATCAGACTAGAAAGTGAAGAGGAAGGGGTTCCTAGTACTGCAATTCGGGAAATTTC
TCTATTAAAGGAACTTCGTCATCCAAATATAGTCAGTCTTCAGGATGTGCTTATGCAGGATTCC
AGGTTATATCTCATCTTTGAGTTTCTTTCCATGGATCTGAAGAAATACTTGGATTCTATCCCTC
CTGGTCAGTACATGGATTCTTCACTTGTTAAGAGTTATTTATACCAAATCCTACAGGGGATTGT
GTTTTGTCACTCTAGAAGAGTTCTTCACAGAGACTTAAAACCTCAAAATCTCTTGATTGATGAC
AAAGGAACAATTAAACTGGCTGATTTTGGCCTTGCCAGAGCTTTTGGAATACCTATTAGAGTAT
ATACACATGAGGTAGTAACACTCTGGTACAGATCTCCAGAAGTATTGCTGGGGTCAGCTCGTTA
CTCAACTCCAGTTGACATTTGGAGTATAGGCACCATATTTGCTGAACTAGCAACTAAGAAACCA
CTTTTCCATGGGGATTCAGAAATTGATCAACTCTTCAGGATTTTCAGAGCTTTGGGCACTCCCA
ATAATGAAGTGTGGCCAGAAGTGGAATCTTTACAGGACTATAAGAATACATTTCCCAAATGGAA
ACCAGGAAGCCTAGCATCCCATGTCAAAAACTTGGATGAAAATGGCTTGGATTTGCTCTCGAAA
ATGTTAATCTATGATCCAGCCAAACGAATTTCTGGCAAAATGGCACTGAATCATCCATATTTTA
ATGATTTGGACAATCAGATTAAGAAGATGTAGCTTTCTGACAAAAAGTTTCCATATGTTATATC
AACAGATAGTTGTGTTTTTATTGTTAACTCTTGTCTATTTTTGTCTTATATATATTTCTTTGTT
ATCAAACTTCAGCTGTACTTCGTCTTCTAATTTCAAAAATATAACTTAAAAATGTAAATATTCT
ATTATGAATTTAAATATAATTCTGTAAATGTGTGTAGGTCTCACTGTAACAACTATTTGTTACT
ATAATAAAACTATAATATTGATGTCAGGAATCAGGAAAAAATTTGAGTTGGCTTAAATCATCTC
AGTCCTTATGGCAGTTTTATTTTCCTGTAGTTGGAACTACTAAAATTTAGGAAAATGCTAAGTT
CAAGTTTCGTAATGCTTTGAAGTATTTTTATGTTCTGAATGTTTAAATGTTCTCATCAGTTTCT
TGCCATGTTGTTAACTATACAACCTGGCTAAAGATGAATATTTTTCTACTGGTATTTTAATTTT
TGACCTAAATGTTTAAGCATTCGGAATGAGAAAACTATACAGATTTGAGAAATGATGCTAAATT
TATAGGAGTTTTCAGTAACTTAAAAAGCTAACATGAGAGCATGCCAAAATTTGCTAAGTCTTAC
AAAGATCAAGGGCTGTCCGCAACAGGGAAGAACAGTTTTGAAAATTTATGAACTATCTTATTTT
TAGGTAGGTTTTGAAAGCTTTTTGTCTAAGTGAATTCTTATGCCTTGGTCAGAGTAATAACTGA
AGGAGTTGCTTGTCTTGGCTTTCGAGTCTCAGTTTAAAACTACACATTTTGACAGTGTTTATTA
GTAGCCATCTAAAAAGGCTCTAATGTATATTTAACTAAAATTACTAGCTTTGGGAATTAAACTG
TTTAACGAATAA

hide sequence

Protein Sequences


Protein RefSeqs	XP_003830379	(Get FASTA)	NCBI Sequence Viewer
	XP_008954060	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000034790
	ENSPPAP00000034790.1
	ENSPPAP00000034798.1

RefSeq Acc Id:	XP_003830379 ⟸ XM_003830331
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9C1X9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIV SLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRD LKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGT IFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNL DENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM hide sequence

RefSeq Acc Id:

XP_008954060 ⟸ XM_008955812

- Peptide Label:

isoform X1

- Sequence:

show sequence

MEDYTKIEKIGEGMFRSIYGTNEGYIPSPVPRLQQNILDSPGTYGVVYKGRHKTTGQVVAMKKI
RLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQY
MDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE
VVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEV
WPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD
NQIKKM

hide sequence

RefSeq Acc Id:

ENSPPAP00000034790 ⟸ ENSPPAT00000057675

RefSeq Acc Id:

ENSPPAP00000034798 ⟸ ENSPPAT00000057683

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040220	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000057675.1	UniProtKB/TrEMBL
	ENSPPAT00000057683.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	pps:100996071	UniProtKB/TrEMBL
NCBI Gene	CDK1	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/TrEMBL
	CYCLIN-DEPENDENT KINASE 1	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PIRSF	Integrin-linked_kinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9BYQ1_PANPA	UniProtKB/TrEMBL
	A0A2R9C1X9	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD