TGM2 (transglutaminase 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: TGM2 (transglutaminase 2) Pan paniscus
Analyze
Symbol: TGM2
Name: transglutaminase 2
RGD ID: 11924178
Description: ENCODES a protein that exhibits GTP binding (ortholog); identical protein binding (ortholog); phospholipase binding (ortholog); INVOLVED IN blood vessel remodeling (ortholog); branching involved in salivary gland morphogenesis (ortholog); dopamine secretion (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ASSOCIATED WITH Brain Neoplasms (ortholog); Breast Neoplasms (ortholog); celiac disease (ortholog); FOUND IN cytoplasm (ortholog); perinuclear region of cytoplasm (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein-glutamine gamma-glutamyltransferase 2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,851,557 - 43,889,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,844,655 - 43,881,956 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,450,845 - 34,488,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,561,819 - 35,599,099 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,561,819 - 35,599,042 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TGM2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,851,557 - 43,889,993 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,844,655 - 43,881,956 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02034,450,845 - 34,488,106 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12035,561,819 - 35,599,099 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,561,819 - 35,599,042 (-)Ensemblpanpan1.1panPan2
TGM2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382038,127,385 - 38,168,475 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2038,127,385 - 38,166,578 (-)EnsemblGRCh38hg38GRCh38
GRCh372036,755,787 - 36,794,910 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,190,277 - 36,227,114 (-)NCBINCBI36Build 36hg18NCBI36
Build 342036,199,764 - 36,227,114NCBI
Celera2033,465,637 - 33,502,475 (-)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2033,493,671 - 33,530,533 (-)NCBIHuRef
CHM1_12036,660,115 - 36,696,950 (-)NCBICHM1_1
T2T-CHM13v2.02039,852,468 - 39,893,578 (-)NCBIT2T-CHM13v2.0
Tgm2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,958,325 - 157,988,312 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,958,322 - 157,988,356 (-)EnsemblGRCm39 Ensembl
GRCm382158,116,405 - 158,146,392 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,116,402 - 158,146,436 (-)EnsemblGRCm38mm10GRCm38
MGSCv372157,942,141 - 157,972,128 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,807,846 - 157,837,833 (-)NCBIMGSCv36mm8
Celera2164,061,515 - 164,091,498 (-)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.72NCBI
Tgm2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83167,192,612 - 167,221,845 (-)NCBIGRCr8
mRatBN7.23146,772,684 - 146,801,924 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,772,687 - 146,801,981 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,598,013 - 150,627,250 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03159,097,613 - 159,126,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,839,077 - 156,868,039 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,597,165 - 154,627,257 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,597,168 - 154,627,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03160,977,905 - 161,007,261 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,832,866 - 148,862,385 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,738,777 - 148,768,294 (-)NCBI
Celera3145,473,663 - 145,503,117 (-)NCBICelera
Cytogenetic Map3q42NCBI
Tgm2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544518,544,183 - 18,576,570 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544518,544,192 - 18,576,576 (+)NCBIChiLan1.0ChiLan1.0
TGM2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,631,339 - 26,662,723 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,628,009 - 26,663,840 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,277,181 - 26,308,444 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02427,327,862 - 27,359,126 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2427,295,164 - 27,359,267 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,602,350 - 26,633,607 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,710,189 - 26,741,409 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02427,198,294 - 27,229,594 (-)NCBIUU_Cfam_GSD_1.0
Tgm2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,541,933 - 175,571,217 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,178,293 - 3,207,561 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,178,244 - 3,207,551 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGM2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,186,770 - 41,221,637 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11741,186,765 - 41,221,686 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,592,093 - 46,629,982 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGM2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,585,827 - 25,623,961 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl225,585,865 - 25,624,280 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605074,426,778 - 74,465,107 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tgm2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248421,491,584 - 1,522,287 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248421,491,583 - 1,522,293 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008966379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000033583   ⟹   ENSPPAP00000010928
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2035,561,819 - 35,599,042 (-)Ensembl
RefSeq Acc Id: XM_008966379   ⟹   XP_008964627
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22143,851,557 - 43,889,993 (-)NCBI
NHGRI_mPanPan12043,844,655 - 43,881,956 (-)NCBI
Mhudiblu_PPA_v02034,450,845 - 34,488,106 (-)NCBI
PanPan1.12035,561,819 - 35,599,099 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008964627 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000010928
  ENSPPAP00000010928.1
Reference Protein Sequences
RefSeq Acc Id: XP_008964627   ⟸   XM_008966379
- UniProtKB: A0A2R9A118 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000010928   ⟸   ENSPPAT00000033583
Protein Domains
Transglutaminase-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028674 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033583.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.90.260.10 UniProtKB/TrEMBL
InterPro Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Transglutaminase-like UniProtKB/TrEMBL
  Transglutaminase-like_sf UniProtKB/TrEMBL
  Transglutaminase_animal UniProtKB/TrEMBL
  Transglutaminase_AS UniProtKB/TrEMBL
  Transglutaminase_C UniProtKB/TrEMBL
  Transglutaminase_C_sf UniProtKB/TrEMBL
  Transglutaminase_N UniProtKB/TrEMBL
KEGG Report pps:100994169 UniProtKB/TrEMBL
NCBI Gene TGM2 ENTREZGENE
PANTHER PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE UniProtKB/TrEMBL
  PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE 2 UniProtKB/TrEMBL
Pfam Transglut_C UniProtKB/TrEMBL
  Transglut_core UniProtKB/TrEMBL
  Transglut_N UniProtKB/TrEMBL
PIRSF TGM_EBP42 UniProtKB/TrEMBL
PROSITE TRANSGLUTAMINASES UniProtKB/TrEMBL
SMART TGc UniProtKB/TrEMBL
Superfamily-SCOP SSF49309 UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A2R9A118 ENTREZGENE, UniProtKB/TrEMBL