PFKM (phosphofructokinase, muscle) - Rat Genome Database

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Gene: PFKM (phosphofructokinase, muscle) Pan paniscus
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Symbol: PFKM
Name: phosphofructokinase, muscle
RGD ID: 11920831
Description: ENCODES a protein that exhibits 6-phosphofructokinase activity (ortholog); AMP binding (ortholog); ATP binding (ortholog); INVOLVED IN canonical glycolysis (ortholog); carbohydrate phosphorylation (ortholog); fructose 1,6-bisphosphate metabolic process (ortholog); PARTICIPATES IN Fanconi syndrome pathway; glycogen storage disease type VII pathway; glycolysis pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); genetic disease (ortholog); glycogen storage disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP-dependent 6-phosphofructokinase, muscle type
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21046,018,686 - 46,059,557 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11246,015,444 - 46,056,280 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01240,584,321 - 40,625,245 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11241,459,346 - 41,500,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,459,346 - 41,499,476 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PFKM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21046,018,686 - 46,059,557 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11246,015,444 - 46,056,280 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01240,584,321 - 40,625,245 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11241,459,346 - 41,500,101 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1241,459,346 - 41,499,476 (-)Ensemblpanpan1.1panPan2
PFKM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381248,105,353 - 48,146,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1248,105,139 - 48,146,404 (+)EnsemblGRCh38hg38GRCh38
GRCh371248,499,136 - 48,540,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361246,802,817 - 46,826,154 (+)NCBINCBI36Build 36hg18NCBI36
Build 341246,802,814 - 46,826,154NCBI
Celera1247,297,160 - 47,337,691 (+)NCBICelera
Cytogenetic Map12q13.11NCBI
HuRef1245,531,136 - 45,571,668 (+)NCBIHuRef
CHM1_11248,465,088 - 48,505,624 (+)NCBICHM1_1
T2T-CHM13v2.01248,066,690 - 48,107,749 (+)NCBIT2T-CHM13v2.0
Pfkm
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391597,990,470 - 98,030,328 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1597,990,470 - 98,030,332 (+)EnsemblGRCm39 Ensembl
GRCm381598,092,589 - 98,132,447 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,092,589 - 98,132,451 (+)EnsemblGRCm38mm10GRCm38
MGSCv371597,923,020 - 97,962,878 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361597,940,155 - 97,960,485 (+)NCBIMGSCv36mm8
Celera15100,219,444 - 100,262,084 (+)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.09NCBI
Pfkm
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,100,684 - 131,138,250 (+)NCBIGRCr8
mRatBN7.27129,221,679 - 129,259,192 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7129,221,653 - 129,259,192 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,031,658 - 131,055,839 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07133,257,199 - 133,281,380 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07133,169,669 - 133,193,851 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07139,702,066 - 139,722,132 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7139,685,573 - 139,722,132 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07138,837,772 - 138,857,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47136,826,122 - 136,846,040 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17136,898,639 - 136,922,477 (+)NCBI
Celera7125,730,934 - 125,751,002 (+)NCBICelera
RH 3.4 Map71088.6RGD
Cytogenetic Map7q36NCBI
Pfkm
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555006,978,893 - 7,022,309 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555006,979,169 - 7,020,375 (+)NCBIChiLan1.0ChiLan1.0
PFKM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1276,620,300 - 6,640,649 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl276,620,300 - 6,663,670 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2739,641,501 - 39,686,323 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0276,687,848 - 6,732,671 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl276,687,848 - 6,732,740 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,625,373 - 6,670,151 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0276,660,147 - 6,704,882 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02739,930,101 - 39,974,930 (+)NCBIUU_Cfam_GSD_1.0
Pfkm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494567,132,891 - 67,175,202 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365126,006,046 - 6,032,899 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365126,006,247 - 6,031,939 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFKM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl578,476,123 - 78,526,997 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1578,475,473 - 78,525,052 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2581,673,123 - 81,695,166 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q25NCBI
PFKM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11144,332,857 - 44,378,273 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1144,334,605 - 44,377,877 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037202,000,136 - 202,046,219 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfkm
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248164,131,752 - 4,156,749 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248164,132,511 - 4,156,809 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000052009   ⟹   ENSPPAP00000029161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,459,346 - 41,499,476 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052035   ⟹   ENSPPAP00000029187
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,459,742 - 41,497,984 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052079   ⟹   ENSPPAP00000029230
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,459,742 - 41,482,578 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052097   ⟹   ENSPPAP00000029250
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,459,742 - 41,482,578 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052108   ⟹   ENSPPAP00000029259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,459,742 - 41,482,578 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052125   ⟹   ENSPPAP00000029276
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,470,604 - 41,482,578 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052129   ⟹   ENSPPAP00000029280
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,473,292 - 41,482,578 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052135   ⟹   ENSPPAP00000029286
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1241,479,896 - 41,497,984 (-)Ensembl
RefSeq Acc Id: XM_003825786   ⟹   XP_003825834
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21046,018,686 - 46,045,546 (-)NCBI
NHGRI_mPanPan11246,015,444 - 46,042,304 (-)NCBI
Mhudiblu_PPA_v01240,584,321 - 40,611,146 (-)NCBI
PanPan1.11241,459,346 - 41,486,117 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951129   ⟹   XP_008949377
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21046,018,686 - 46,045,548 (-)NCBI
NHGRI_mPanPan11246,015,444 - 46,042,306 (-)NCBI
Mhudiblu_PPA_v01240,584,321 - 40,611,172 (-)NCBI
PanPan1.11241,459,346 - 41,486,117 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008951130   ⟹   XP_008949378
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21046,018,686 - 46,059,557 (-)NCBI
NHGRI_mPanPan11246,015,444 - 46,056,280 (-)NCBI
Mhudiblu_PPA_v01240,584,321 - 40,625,245 (-)NCBI
PanPan1.11241,459,346 - 41,500,101 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055095709   ⟹   XP_054951684
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21046,018,686 - 46,059,394 (-)NCBI
NHGRI_mPanPan11246,015,444 - 46,056,152 (-)NCBI
RefSeq Acc Id: XM_055095710   ⟹   XP_054951685
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21046,018,686 - 46,058,733 (-)NCBI
NHGRI_mPanPan11246,015,444 - 46,055,491 (-)NCBI
RefSeq Acc Id: XP_008949378   ⟸   XM_008951130
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BHW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003825834   ⟸   XM_003825786
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BHW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008949377   ⟸   XM_008951129
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BHW7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000029187   ⟸   ENSPPAT00000052035
RefSeq Acc Id: ENSPPAP00000029161   ⟸   ENSPPAT00000052009
RefSeq Acc Id: ENSPPAP00000029230   ⟸   ENSPPAT00000052079
RefSeq Acc Id: ENSPPAP00000029250   ⟸   ENSPPAT00000052097
RefSeq Acc Id: ENSPPAP00000029259   ⟸   ENSPPAT00000052108
RefSeq Acc Id: ENSPPAP00000029280   ⟸   ENSPPAT00000052129
RefSeq Acc Id: ENSPPAP00000029276   ⟸   ENSPPAT00000052125
RefSeq Acc Id: ENSPPAP00000029286   ⟸   ENSPPAT00000052135
RefSeq Acc Id: XP_054951684   ⟸   XM_055095709
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054951685   ⟸   XM_055095710
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BRB6 (UniProtKB/TrEMBL)
Protein Domains
Phosphofructokinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037410 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052009.1 UniProtKB/TrEMBL
  ENSPPAT00000052035.1 UniProtKB/TrEMBL
  ENSPPAT00000052079.1 UniProtKB/TrEMBL
  ENSPPAT00000052097.1 UniProtKB/TrEMBL
  ENSPPAT00000052108.1 UniProtKB/TrEMBL
  ENSPPAT00000052125.1 UniProtKB/TrEMBL
  ENSPPAT00000052129.1 UniProtKB/TrEMBL
  ENSPPAT00000052135.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.450 UniProtKB/TrEMBL
  3.40.50.460 UniProtKB/TrEMBL
InterPro 6-Pfructokinase_euk UniProtKB/TrEMBL
  ATP_PFK UniProtKB/TrEMBL
  PFK_vert-type UniProtKB/TrEMBL
  Phosphofructokinase_CS UniProtKB/TrEMBL
  Phosphofructokinase_dom UniProtKB/TrEMBL
  PKF_sf UniProtKB/TrEMBL
NCBI Gene PFKM ENTREZGENE
PANTHER ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, MUSCLE TYPE UniProtKB/TrEMBL
  PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Pfam PFK UniProtKB/TrEMBL
PIRSF ATP_PFK_euk UniProtKB/TrEMBL
PRINTS PHFRCTKINASE UniProtKB/TrEMBL
PROSITE PHOSPHOFRUCTOKINASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53784 UniProtKB/TrEMBL
UniProt A0A2R9BHU8_PANPA UniProtKB/TrEMBL
  A0A2R9BHW7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BHY0_PANPA UniProtKB/TrEMBL
  A0A2R9BHZ8_PANPA UniProtKB/TrEMBL
  A0A2R9BLA9_PANPA UniProtKB/TrEMBL
  A0A2R9BRB6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BRS1_PANPA UniProtKB/TrEMBL
  A0A2R9BRT0_PANPA UniProtKB/TrEMBL