CASP14 (caspase 14) - Rat Genome Database

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Gene: CASP14 (caspase 14) Pan paniscus
Analyze
Symbol: CASP14
Name: caspase 14
RGD ID: 11907460
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity (inferred); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Autosomal Recessive Congenital Ichthyosis 12 (ortholog); genetic disease (ortholog); FOUND IN cornified envelope (ortholog); cytoplasm (ortholog); keratin filament (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: caspase-14
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,938,212 - 19,970,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,955,262 - 18,987,678 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,594,810 - 14,604,109 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,565,543 - 15,574,402 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,565,543 - 15,574,402 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component
cornified envelope  (IEA,ISO)
cytoplasm  (IEA,ISO)
cytosol  (IEA)
keratin filament  (ISO)
mitochondrion  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
CASP14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22019,938,212 - 19,970,641 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11918,955,262 - 18,987,678 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01914,594,810 - 14,604,109 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11915,565,543 - 15,574,402 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1915,565,543 - 15,574,402 (+)Ensemblpanpan1.1panPan2
CASP14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381915,049,480 - 15,058,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1915,049,480 - 15,058,293 (+)EnsemblGRCh38hg38GRCh38
GRCh371915,160,291 - 15,169,104 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361915,024,015 - 15,027,900 (+)NCBINCBI36Build 36hg18NCBI36
Build 341915,024,014 - 15,027,900NCBI
Celera1915,058,743 - 15,062,628 (+)NCBICelera
Cytogenetic Map19p13.12NCBI
HuRef1914,727,867 - 14,736,682 (+)NCBIHuRef
CHM1_11915,159,760 - 15,168,573 (+)NCBICHM1_1
T2T-CHM13v2.01915,174,417 - 15,183,232 (+)NCBIT2T-CHM13v2.0
Casp14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391078,547,829 - 78,554,181 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1078,547,825 - 78,554,128 (-)EnsemblGRCm39 Ensembl
GRCm381078,711,995 - 78,718,347 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,711,991 - 78,718,294 (-)EnsemblGRCm38mm10GRCm38
MGSCv371078,174,740 - 78,181,038 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361078,115,126 - 78,121,371 (-)NCBIMGSCv36mm8
Celera1079,733,914 - 79,740,355 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Casp14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8711,577,315 - 11,583,987 (+)NCBIGRCr8
mRatBN7.2710,929,759 - 10,932,591 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl710,926,725 - 10,933,405 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx713,750,087 - 13,752,901 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0715,627,533 - 15,630,347 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0713,505,382 - 13,508,196 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0713,938,376 - 13,944,286 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl713,938,302 - 13,945,130 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0714,094,304 - 14,099,953 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4712,487,166 - 12,489,998 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1712,456,557 - 12,489,998 (+)NCBI
Celera79,047,174 - 9,050,006 (+)NCBICelera
Cytogenetic Map7q11NCBI
Casp14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554958,213,763 - 8,221,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554958,214,512 - 8,221,124 (-)NCBIChiLan1.0ChiLan1.0
CASP14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12047,060,351 - 47,067,169 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2047,062,278 - 47,065,001 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2046,911,092 - 46,917,669 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02047,553,425 - 47,560,009 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2047,553,782 - 47,560,035 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12046,784,855 - 46,791,428 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02047,204,643 - 47,211,219 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02047,475,191 - 47,481,766 (-)NCBIUU_Cfam_GSD_1.0
Casp14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118205,846,067 - 205,852,182 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365965,396,866 - 5,399,278 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365965,396,866 - 5,399,255 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl262,524,183 - 62,531,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1262,522,294 - 62,531,594 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2262,076,316 - 62,089,874 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CASP14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1613,649,993 - 13,654,309 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl613,648,598 - 13,652,821 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660745,899,601 - 5,914,400 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Casp14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249012,127,743 - 2,130,496 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249012,125,575 - 2,131,656 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000036739   ⟹   ENSPPAP00000014064
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1915,565,543 - 15,574,402 (+)Ensembl
RefSeq Acc Id: XM_055104182   ⟹   XP_054960157
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,938,212 - 19,970,641 (+)NCBI
NHGRI_mPanPan11918,955,262 - 18,987,678 (+)NCBI
RefSeq Acc Id: XM_055104183   ⟹   XP_054960158
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22019,938,212 - 19,969,805 (+)NCBI
NHGRI_mPanPan11918,955,262 - 18,986,842 (+)NCBI
Protein Sequences
Protein RefSeqs XP_054960157 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960158 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000014064.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000014064   ⟸   ENSPPAT00000036739
RefSeq Acc Id: XP_054960157   ⟸   XM_055104182
- UniProtKB: A0A2R9A9W3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960158   ⟸   XM_055104183
- UniProtKB: A0A2R9A9W3 (UniProtKB/TrEMBL)
Protein Domains
Caspase family p10   Caspase family p20


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000030191 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000036739.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1460 UniProtKB/TrEMBL
InterPro Caspase-like_dom_sf UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/TrEMBL
  Pept_C14A UniProtKB/TrEMBL
KEGG Report pps:100975084 UniProtKB/TrEMBL
NCBI Gene CASP14 ENTREZGENE
PANTHER CASPASE 23-RELATED UniProtKB/TrEMBL
  MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE UniProtKB/TrEMBL
Pfam Peptidase_C14 UniProtKB/TrEMBL
PRINTS IL1BCENZYME UniProtKB/TrEMBL
PROSITE CASPASE_CYS UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/TrEMBL
SMART CASc UniProtKB/TrEMBL
Superfamily-SCOP SSF52129 UniProtKB/TrEMBL
UniProt A0A2R9A9W3 ENTREZGENE, UniProtKB/TrEMBL