TXN (thioredoxin) - Rat Genome Database

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Pathways
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Gene: TXN (thioredoxin) Pan paniscus
Analyze
Symbol: TXN
Name: thioredoxin
RGD ID: 11903407
Description: ENCODES a protein that exhibits enzyme binding (ortholog); INVOLVED IN cell redox homeostasis (ortholog); cellular response to antibiotic (ortholog); cellular response to glucose stimulus (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Arterial Occlusive Diseases (ortholog); Breast Neoplasms (ortholog); FOUND IN axon (ortholog); dendrite (ortholog); neuronal cell body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21129,150,207 - 29,162,897 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1929,152,695 - 29,165,262 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0981,399,056 - 81,411,607 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19109,565,557 - 109,578,311 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9109,565,557 - 109,578,311 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TXN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21129,150,207 - 29,162,897 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1929,152,695 - 29,165,262 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0981,399,056 - 81,411,607 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19109,565,557 - 109,578,311 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9109,565,557 - 109,578,311 (-)Ensemblpanpan1.1panPan2
TXN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389110,243,810 - 110,256,507 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9110,243,810 - 110,256,507 (-)EnsemblGRCh38hg38GRCh38
GRCh379113,006,090 - 113,018,787 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369112,046,131 - 112,058,599 (-)NCBINCBI36Build 36hg18NCBI36
Build 349110,085,864 - 110,098,333NCBI
Celera983,507,936 - 83,520,398 (-)NCBICelera
Cytogenetic Map9q31.3NCBI
HuRef982,607,811 - 82,620,710 (-)NCBIHuRef
CHM1_19113,152,543 - 113,165,343 (-)NCBICHM1_1
T2T-CHM13v2.09122,413,340 - 122,426,045 (-)NCBIT2T-CHM13v2.0
Txn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39457,943,373 - 57,956,411 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl457,943,373 - 57,956,411 (-)EnsemblGRCm39 Ensembl
GRCm38457,943,373 - 57,956,411 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl457,943,373 - 57,956,411 (-)EnsemblGRCm38mm10GRCm38
MGSCv37457,956,245 - 57,969,283 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36458,037,427 - 58,050,345 (-)NCBIMGSCv36mm8
Celera457,856,035 - 57,868,968 (-)NCBICelera
Cytogenetic Map4B3NCBI
cM Map431.87NCBI
Txn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8577,507,455 - 77,519,685 (-)NCBIGRCr8
mRatBN7.2572,712,334 - 72,724,564 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl572,711,933 - 72,724,629 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx574,603,651 - 74,615,881 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0576,425,269 - 76,437,499 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0576,397,400 - 76,409,630 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0575,049,735 - 75,057,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl575,049,747 - 75,057,752 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0579,201,386 - 79,209,384 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4575,921,365 - 75,933,595 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1575,926,428 - 75,938,789 (-)NCBI
Celera571,558,162 - 71,570,393 (-)NCBICelera
RH 3.4 Map5494.0RGD
Cytogenetic Map5q24NCBI
LOC100687127
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X82,986,288 - 82,986,753 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX69,064,524 - 69,064,989 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X84,637,255 - 84,637,720 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1X82,113,902 - 82,114,367 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X83,808,036 - 83,808,501 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X83,636,876 - 83,637,341 (-)NCBIUU_Cfam_GSD_1.0
Txn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947180,444,054 - 180,454,833 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365592,811,782 - 2,822,528 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365592,811,786 - 2,822,528 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TXN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1251,263,175 - 251,277,988 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11251,264,180 - 251,278,000 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21282,027,082 - 282,035,642 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap1qNCBI
TXN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11229,296,166 - 29,308,979 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603513,456,569 - 13,469,439 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Txn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247581,318,529 - 1,329,011 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247581,318,108 - 1,329,011 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003810884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000062184   ⟹   ENSPPAP00000039274
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9109,565,557 - 109,578,311 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000062188   ⟹   ENSPPAP00000039278
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl9109,565,602 - 109,578,311 (-)Ensembl
RefSeq Acc Id: XM_003810884   ⟹   XP_003810932
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21129,150,207 - 29,162,897 (+)NCBI
NHGRI_mPanPan1929,152,695 - 29,165,262 (+)NCBI
Mhudiblu_PPA_v0981,399,056 - 81,411,607 (-)NCBI
PanPan1.19109,565,602 - 109,578,311 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003810932 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000039274.1
  ENSPPAP00000039278
  ENSPPAP00000039278.1
  ENSPPAP00000039777.1
Reference Protein Sequences
RefSeq Acc Id: XP_003810932   ⟸   XM_003810884
- UniProtKB: A0A2R9CE55 (UniProtKB/TrEMBL),   A0A2R9CNH0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000039274   ⟸   ENSPPAT00000062184
RefSeq Acc Id: ENSPPAP00000039278   ⟸   ENSPPAT00000062188
Protein Domains
Thioredoxin


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000042345 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAG00000042568 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000062184.1 UniProtKB/TrEMBL
  ENSPPAT00000062188.1 UniProtKB/TrEMBL
  ENSPPAT00000062689.1 UniProtKB/TrEMBL
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro Thioredoxin UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
KEGG Report pps:100984512 UniProtKB/TrEMBL
NCBI Gene TXN ENTREZGENE
PANTHER THIOREDOXIN UniProtKB/TrEMBL
  THIOREDOXIN-LIKE PROTEIN 1 UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/TrEMBL
PIRSF Thioredoxin UniProtKB/TrEMBL
PRINTS THIOREDOXIN UniProtKB/TrEMBL
PROSITE THIOREDOXIN_1 UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A2R9CBM3_PANPA UniProtKB/TrEMBL
  A0A2R9CE55 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CNH0 ENTREZGENE, UniProtKB/TrEMBL