KCNS1 (potassium voltage-gated channel modifier subfamily S member 1) - Rat Genome Database

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Gene: KCNS1 (potassium voltage-gated channel modifier subfamily S member 1) Pan paniscus
Analyze
Symbol: KCNS1
Name: potassium voltage-gated channel modifier subfamily S member 1
RGD ID: 11875481
Description: ENCODES a protein that exhibits delayed rectifier potassium channel activity (inferred); potassium channel activity (inferred); potassium channel regulator activity (inferred); INVOLVED IN potassium ion transmembrane transport (inferred); potassium ion transport (inferred); protein homooligomerization (inferred); ASSOCIATED WITH focal epilepsy (ortholog); genetic disease (ortholog); intracranial hypertension (ortholog); FOUND IN membrane (inferred); monoatomic ion channel complex (inferred); perinuclear region of cytoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: potassium voltage-gated channel subfamily S member 1; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,825,312 - 50,834,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,818,419 - 50,827,322 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,422,847 - 41,431,752 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,514,300 - 42,524,341 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,515,401 - 42,524,192 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KCNS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22150,825,312 - 50,834,225 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12050,818,419 - 50,827,322 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,422,847 - 41,431,752 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,514,300 - 42,524,341 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,515,401 - 42,524,192 (-)Ensemblpanpan1.1panPan2
KCNS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,091,214 - 45,101,127 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,091,214 - 45,101,127 (-)EnsemblGRCh38hg38GRCh38
GRCh372043,719,855 - 43,729,768 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,154,364 - 43,163,167 (-)NCBINCBI36Build 36hg18NCBI36
Build 342043,154,363 - 43,163,167NCBI
Celera2040,429,593 - 40,438,396 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2040,462,848 - 40,471,652 (-)NCBIHuRef
CHM1_12043,623,697 - 43,632,500 (-)NCBICHM1_1
T2T-CHM13v2.02046,827,118 - 46,837,031 (-)NCBIT2T-CHM13v2.0
Kcns1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,005,539 - 164,013,865 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,005,539 - 164,013,033 (-)EnsemblGRCm39 Ensembl
GRCm382164,163,619 - 164,171,113 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,163,619 - 164,171,113 (-)EnsemblGRCm38mm10GRCm38
MGSCv372163,989,355 - 163,996,849 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362163,855,746 - 163,862,530 (-)NCBIMGSCv36mm8
Celera2170,095,175 - 170,102,667 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.6NCBI
Kcns1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,255,028 - 173,262,432 (-)NCBIGRCr8
mRatBN7.23152,835,642 - 152,843,032 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3152,835,644 - 152,842,960 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3156,643,137 - 156,650,455 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,142,074 - 165,149,392 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03162,886,437 - 162,893,887 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03160,554,423 - 160,561,820 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3160,554,425 - 160,561,741 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03166,739,097 - 166,746,473 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,103,400 - 155,110,718 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,009,435 - 155,016,754 (-)NCBI
Celera3151,483,732 - 151,491,050 (-)NCBICelera
Cytogenetic Map3q42NCBI
Kcns1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544512,293,394 - 12,299,787 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544512,293,394 - 12,299,741 (+)NCBIChiLan1.0ChiLan1.0
KCNS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12432,472,292 - 32,478,986 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2432,474,881 - 32,479,717 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,117,691 - 32,124,386 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,183,125 - 33,189,820 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,183,110 - 33,190,552 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12432,444,433 - 32,451,126 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02432,559,506 - 32,568,916 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,101,321 - 33,108,016 (-)NCBIUU_Cfam_GSD_1.0
Kcns1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640192,217,629 - 192,224,162 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,671,264 - 7,678,139 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,671,664 - 7,677,806 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1747,483,947 - 47,492,567 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11747,483,943 - 47,491,071 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,101,856 - 53,108,983 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,715,666 - 18,724,955 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605067,365,392 - 67,375,593 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Kcns1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247909,399,965 - 9,407,376 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247909,399,267 - 9,405,503 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008951331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000050993   ⟹   ENSPPAP00000028149
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2042,515,401 - 42,524,192 (-)Ensembl
RefSeq Acc Id: XM_008951331   ⟹   XP_008949579
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22150,825,312 - 50,834,225 (-)NCBI
NHGRI_mPanPan12050,818,419 - 50,827,322 (-)NCBI
Mhudiblu_PPA_v02041,422,847 - 41,431,752 (-)NCBI
PanPan1.12042,514,300 - 42,524,195 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008949579 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000028149.1
Reference Protein Sequences
RefSeq Acc Id: XP_008949579   ⟸   XM_008951331
- Sequence:
RefSeq Acc Id: ENSPPAP00000028149   ⟸   ENSPPAT00000050993
Protein Domains
BTB


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037133 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050993.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/TrEMBL
  1.20.120.350 UniProtKB/TrEMBL
InterPro BTB/POZ_dom UniProtKB/TrEMBL
  Ion_trans_dom UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv UniProtKB/TrEMBL
  K_chnl_volt-dep_Kv9 UniProtKB/TrEMBL
  SKP1/BTB/POZ_sf UniProtKB/TrEMBL
  T1-type_BTB UniProtKB/TrEMBL
  Volt_channel_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100984276 UniProtKB/TrEMBL
NCBI Gene KCNS1 ENTREZGENE
PANTHER POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY S MEMBER 1 UniProtKB/TrEMBL
  PTHR11537 UniProtKB/TrEMBL
Pfam BTB_2 UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
PRINTS KCHANNEL UniProtKB/TrEMBL
  KV9CHANNEL UniProtKB/TrEMBL
  KVCHANNEL UniProtKB/TrEMBL
SMART BTB UniProtKB/TrEMBL
Superfamily-SCOP SSF54695 UniProtKB/TrEMBL
  Voltage-gated potassium channels UniProtKB/TrEMBL
UniProt A0A2R9BES1_PANPA UniProtKB/TrEMBL