KRT12 (keratin 12) - Rat Genome Database

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Gene: KRT12 (keratin 12) Pan paniscus
Analyze
Symbol: KRT12
Name: keratin 12
RGD ID: 11856074
Description: ENCODES a protein that exhibits structural molecule activity (inferred); INVOLVED IN cornea development in camera-type eye (ortholog); epithelium development (ortholog); ASSOCIATED WITH corneal dystrophy (ortholog); genetic disease (ortholog); Meesmann corneal dystrophy (ortholog); FOUND IN cytoskeleton (inferred); intermediate filament (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: keratin, type I cytoskeletal 12
RGD Orthologs
Human
Mouse
Rat
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,085,202 - 24,093,635 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,970,876 - 25,984,070 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01716,414,985 - 16,423,417 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,642,038 - 16,648,124 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,642,038 - 16,648,124 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
KRT12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21924,085,202 - 24,093,635 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,970,876 - 25,984,070 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01716,414,985 - 16,423,417 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11716,642,038 - 16,648,124 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1716,642,038 - 16,648,124 (+)Ensemblpanpan1.1panPan2
KRT12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381740,861,303 - 40,867,223 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1740,861,303 - 40,867,223 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,017,555 - 39,023,475 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,270,956 - 36,276,988 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,271,080 - 36,276,988NCBI
Celera1735,678,983 - 35,685,022 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1734,811,768 - 34,817,815 (-)NCBIHuRef
CHM1_11739,252,770 - 39,258,802 (-)NCBICHM1_1
T2T-CHM13v2.01741,725,618 - 41,731,542 (-)NCBIT2T-CHM13v2.0
Krt12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391199,306,490 - 99,313,419 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1199,306,492 - 99,313,085 (-)EnsemblGRCm39 Ensembl
GRCm381199,415,664 - 99,422,593 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1199,415,666 - 99,422,259 (-)EnsemblGRCm38mm10GRCm38
MGSCv371199,276,978 - 99,283,573 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361199,231,756 - 99,238,346 (-)NCBIMGSCv36mm8
Celera11111,952,955 - 111,954,261 (+)NCBICelera
Celera11111,682,897 - 111,684,405 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1162.92NCBI
Krt12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81084,866,965 - 84,874,265 (-)NCBIGRCr8
mRatBN7.21084,370,803 - 84,378,103 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1084,370,883 - 84,378,045 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1089,314,464 - 89,321,785 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01088,812,593 - 88,819,914 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01084,204,563 - 84,211,884 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01087,328,547 - 87,336,710 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1087,328,549 - 87,335,823 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,124,333 - 87,132,201 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41088,321,126 - 88,328,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11088,335,495 - 88,343,129 (-)NCBI
Celera1083,110,103 - 83,116,993 (-)NCBICelera
Cytogenetic Map10q31NCBI
KRT12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,823,976 - 21,829,557 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,823,976 - 21,829,550 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha921,296,821 - 21,302,404 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0922,616,626 - 22,622,208 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl922,616,626 - 22,622,201 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1921,391,112 - 21,396,693 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0921,649,850 - 21,655,431 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,774,332 - 21,779,951 (+)NCBIUU_Cfam_GSD_1.0
LOC101971892
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560221,250,526 - 21,254,399 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649015,820,678 - 15,824,743 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649015,820,754 - 15,824,611 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KRT12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,599,563 - 21,606,912 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,600,163 - 21,607,268 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21221,879,833 - 21,886,530 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KRT12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11665,316,412 - 65,322,890 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1665,316,251 - 65,322,704 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607736,195,840 - 36,201,875 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003831407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000045844   ⟹   ENSPPAP00000023026
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1716,642,038 - 16,648,124 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000045846   ⟹   ENSPPAP00000023028
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1716,642,116 - 16,647,641 (+)Ensembl
RefSeq Acc Id: XM_003831407   ⟹   XP_003831455
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21924,085,202 - 24,093,635 (+)NCBI
NHGRI_mPanPan11725,970,876 - 25,984,070 (+)NCBI
Mhudiblu_PPA_v01716,414,985 - 16,423,417 (+)NCBI
PanPan1.11716,642,038 - 16,648,124 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003831455 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023026.1
  ENSPPAP00000023028.1
RefSeq Acc Id: XP_003831455   ⟸   XM_003831407
- UniProtKB: A0A2R9B0H7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSPPAP00000023026   ⟸   ENSPPAT00000045844
RefSeq Acc Id: ENSPPAP00000023028   ⟸   ENSPPAT00000045846
Protein Domains
IF rod


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034686 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000045844.1 UniProtKB/TrEMBL
  ENSPPAT00000045846.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  Single helix bin UniProtKB/TrEMBL
  Vasodilator-stimulated phosphoprotein UniProtKB/TrEMBL
InterPro IF_conserved UniProtKB/TrEMBL
  IF_rod_dom UniProtKB/TrEMBL
  Keratin_I UniProtKB/TrEMBL
KEGG Report pps:100991477 UniProtKB/TrEMBL
NCBI Gene KRT12 ENTREZGENE
PANTHER KERATIN, TYPE I CYTOSKELETAL 12 UniProtKB/TrEMBL
  PTHR23239 UniProtKB/TrEMBL
Pfam Filament UniProtKB/TrEMBL
PRINTS TYPE1KERATIN UniProtKB/TrEMBL
PROSITE IF_ROD_1 UniProtKB/TrEMBL
  IF_ROD_2 UniProtKB/TrEMBL
SMART Filament UniProtKB/TrEMBL
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/TrEMBL
UniProt A0A2R9B0H7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B4D0_PANPA UniProtKB/TrEMBL