MMP10 (matrix metallopeptidase 10) - Rat Genome Database

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Gene: MMP10 (matrix metallopeptidase 10) Pan paniscus
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Symbol: MMP10
Name: matrix metallopeptidase 10
RGD ID: 11840674
Description: ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); metalloendopeptidase activity (inferred); INVOLVED IN regulation of cell migration (ortholog); ASSOCIATED WITH adrenoleukodystrophy (ortholog); asphyxiating thoracic dystrophy (ortholog); asthma (ortholog); FOUND IN extracellular matrix (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: matrix metallopeptidase 10 (stromelysin 2); stromelysin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,563,643 - 103,574,074 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,651,805 - 104,662,248 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,710,819 - 97,721,263 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,201,665 - 101,212,103 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,201,665 - 101,212,103 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
MMP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,563,643 - 103,574,074 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,651,805 - 104,662,248 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,710,819 - 97,721,263 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,201,665 - 101,212,103 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,201,665 - 101,212,103 (-)Ensemblpanpan1.1panPan2
MMP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,770,502 - 102,780,628 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11102,770,502 - 102,780,628 (-)EnsemblGRCh38hg38GRCh38
GRCh3711102,641,233 - 102,651,359 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,146,444 - 102,156,554 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411102,146,443 - 102,156,554NCBI
Celera1199,802,887 - 99,813,014 (-)NCBICelera
Cytogenetic Map11q22.2NCBI
HuRef1198,569,206 - 98,579,335 (-)NCBIHuRef
CHM1_111102,524,082 - 102,534,205 (-)NCBICHM1_1
T2T-CHM13v2.011102,774,317 - 102,784,440 (-)NCBIT2T-CHM13v2.0
Mmp10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,502,343 - 7,510,243 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl97,502,353 - 7,510,241 (+)EnsemblGRCm39 Ensembl
GRCm3897,502,342 - 7,510,242 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,502,352 - 7,510,240 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,502,360 - 7,510,240 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3697,490,825 - 7,510,240 (+)NCBIMGSCv36mm8
Celera94,892,709 - 4,900,593 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Mmp10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8812,974,707 - 12,982,613 (+)NCBIGRCr8
mRatBN7.284,689,840 - 4,697,748 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,689,840 - 4,697,748 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,649,536 - 8,657,457 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.086,947,308 - 6,955,231 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.084,949,505 - 4,957,411 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,734,348 - 5,742,243 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,734,348 - 5,742,243 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,737,196 - 5,745,091 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,367,842 - 4,375,737 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.184,367,841 - 4,375,737 (+)NCBI
Celera86,249,460 - 6,257,355 (+)NCBICelera
Cytogenetic Map8q11NCBI
Mmp10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554125,965,394 - 5,976,382 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554125,965,388 - 5,976,353 (-)NCBIChiLan1.0ChiLan1.0
Mmp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,338,808 - 86,348,136 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365515,188,395 - 5,197,477 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,147,995 - 94,158,315 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,148,087 - 94,158,097 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604331,719,000 - 31,729,136 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624878107,361 - 117,459 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624878107,330 - 117,654 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003828378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000021026   ⟹   ENSPPAP00000004574
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11101,201,665 - 101,212,103 (-)Ensembl
RefSeq Acc Id: XM_003828378   ⟹   XP_003828426
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29103,563,643 - 103,574,074 (-)NCBI
NHGRI_mPanPan111104,651,805 - 104,662,248 (-)NCBI
Mhudiblu_PPA_v01197,710,819 - 97,721,263 (-)NCBI
PanPan1.111101,201,665 - 101,212,103 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003828426 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000004574.1
RefSeq Acc Id: XP_003828426   ⟸   XM_003828378
- Sequence:
RefSeq Acc Id: ENSPPAP00000004574   ⟸   ENSPPAT00000021026
Protein Domains
Peptidase metallopeptidase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000019189 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000021026.1 UniProtKB/TrEMBL
Gene3D-CATH 2.110.10.10 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro Hemopexin-like_dom UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  M10A_MMP UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/TrEMBL
  Pept_M10A UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/TrEMBL
KEGG Report pps:100996180 UniProtKB/TrEMBL
NCBI Gene MMP10 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/TrEMBL
  STROMELYSIN-2 UniProtKB/TrEMBL
Pfam Hemopexin UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/TrEMBL
PRINTS MATRIXIN UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/TrEMBL
  HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/TrEMBL
SMART SM00120 UniProtKB/TrEMBL
  ZnMc UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF47090 UniProtKB/TrEMBL
  SSF50923 UniProtKB/TrEMBL
UniProt A0A2R8ZHX4_PANPA UniProtKB/TrEMBL