SFTPC (surfactant protein C) - Rat Genome Database

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Gene: SFTPC (surfactant protein C) Pan paniscus
Analyze
Symbol: SFTPC
Name: surfactant protein C
RGD ID: 11829062
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); cellular response to nitric oxide (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH adult respiratory distress syndrome (ortholog); asthma (ortholog); bacterial pneumonia (ortholog); FOUND IN alveolar lamellar body (ortholog); cytoplasm (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pulmonary surfactant-associated protein C
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,343,007 - 18,348,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,345,940 - 18,348,764 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
SFTPC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1818,343,007 - 18,348,764 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl818,345,940 - 18,348,764 (+)Ensemblpanpan1.1panPan2
SFTPC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38822,157,383 - 22,164,479 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl822,156,913 - 22,164,479 (+)EnsemblGRCh38hg38GRCh38
GRCh37822,014,896 - 22,021,992 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36822,075,129 - 22,077,937 (+)NCBINCBI36Build 36hg18NCBI36
Build 34822,075,112 - 22,077,928NCBI
Celera820,981,168 - 20,983,976 (+)NCBICelera
Cytogenetic Map8p21.3NCBI
HuRef820,561,488 - 20,564,296 (+)NCBIHuRef
CHM1_1822,220,843 - 22,223,651 (+)NCBICHM1_1
T2T-CHM13v2.0822,431,328 - 22,438,424 (+)NCBIT2T-CHM13v2.0
Sftpc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391470,758,381 - 70,761,521 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1470,758,389 - 70,761,521 (-)EnsemblGRCm39 Ensembl
GRCm381470,520,941 - 70,524,081 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1470,520,949 - 70,524,081 (-)EnsemblGRCm38mm10GRCm38
MGSCv371470,920,748 - 70,923,888 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361469,256,020 - 69,259,150 (-)NCBIMGSCv36mm8
Celera1468,062,491 - 68,065,631 (-)NCBICelera
Cytogenetic Map14D2NCBI
cM Map1436.32NCBI
Sftpc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81552,006,274 - 52,009,324 (-)NCBIGRCr8
mRatBN7.21545,596,565 - 45,599,615 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1545,596,574 - 45,610,777 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1549,714,437 - 49,717,379 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01550,825,943 - 50,828,885 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01547,685,234 - 47,688,176 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01552,211,538 - 52,214,480 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1552,211,544 - 52,214,616 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01555,935,055 - 55,937,997 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41550,923,105 - 50,926,047 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11550,938,884 - 50,941,827 (-)NCBI
Celera1545,274,971 - 45,277,913 (-)NCBICelera
Cytogenetic Map15p11NCBI
Sftpc
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540345,649,122 - 45,651,837 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540345,649,149 - 45,651,421 (+)NCBIChiLan1.0ChiLan1.0
SFTPC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12535,088,295 - 35,090,995 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2535,088,279 - 35,091,457 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2535,677,864 - 35,680,614 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02535,299,616 - 35,302,366 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2535,299,694 - 35,302,250 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12535,245,093 - 35,247,843 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02535,099,613 - 35,102,363 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02535,255,134 - 35,257,884 (-)NCBIUU_Cfam_GSD_1.0
Sftpc
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494312,588,481 - 12,596,579 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365555,979,417 - 5,982,011 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365555,966,610 - 5,982,083 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFTPC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl146,440,309 - 6,443,095 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1146,440,309 - 6,443,104 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2146,868,096 - 6,880,564 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SFTPC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1820,229,756 - 20,233,568 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl820,230,870 - 20,234,020 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605222,002,517 - 22,009,591 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sftpc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475817,742,415 - 17,744,655 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475817,742,439 - 17,744,664 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000056702   ⟹   ENSPPAP00000033823
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,345,940 - 18,348,764 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056713   ⟹   ENSPPAP00000033834
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,345,956 - 18,348,764 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056721   ⟹   ENSPPAP00000033842
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,346,114 - 18,348,742 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000056728   ⟹   ENSPPAP00000033849
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl818,346,114 - 18,348,105 (+)Ensembl
RefSeq Acc Id: XM_008977247   ⟹   XP_008975495
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,662,171 - 40,666,337 (+)NCBI
NHGRI_mPanPan1816,387,372 - 16,391,523 (+)NCBI
Mhudiblu_PPA_v0821,405,503 - 21,409,438 (+)NCBI
PanPan1.1818,345,956 - 18,348,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024929856   ⟹   XP_024785624
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBI
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBI
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBI
PanPan1.1818,345,956 - 18,348,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024929857   ⟹   XP_024785625
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBI
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBI
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBI
PanPan1.1818,345,956 - 18,348,764 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034965801   ⟹   XP_034821692
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,658,965 - 40,666,346 (+)NCBI
NHGRI_mPanPan1816,384,149 - 16,391,532 (+)NCBI
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBI
RefSeq Acc Id: XM_034965802   ⟹   XP_034821693
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,660,336 - 40,666,337 (+)NCBI
NHGRI_mPanPan1816,385,523 - 16,391,523 (+)NCBI
Mhudiblu_PPA_v0821,403,434 - 21,409,438 (+)NCBI
RefSeq Acc Id: XM_034965804   ⟹   XP_034821695
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,658,965 - 40,666,337 (+)NCBI
NHGRI_mPanPan1816,384,149 - 16,391,523 (+)NCBI
Mhudiblu_PPA_v0821,402,060 - 21,409,438 (+)NCBI
RefSeq Acc Id: XM_034965805   ⟹   XP_034821696
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,662,164 - 40,666,337 (+)NCBI
NHGRI_mPanPan1816,387,372 - 16,391,523 (+)NCBI
Mhudiblu_PPA_v0821,405,496 - 21,409,438 (+)NCBI
RefSeq Acc Id: XM_057302987   ⟹   XP_057158970
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2740,660,336 - 40,666,346 (+)NCBI
NHGRI_mPanPan1816,385,523 - 16,391,532 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008975495   ⟸   XM_008977247
- Peptide Label: isoform X2
- UniProtKB: A0A2R9C5L9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024785624   ⟸   XM_024929856
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_024785625   ⟸   XM_024929857
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034821692   ⟸   XM_034965801
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034821695   ⟸   XM_034965804
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034821693   ⟸   XM_034965802
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034821696   ⟸   XM_034965805
- Peptide Label: isoform X4
RefSeq Acc Id: ENSPPAP00000033823   ⟸   ENSPPAT00000056702
RefSeq Acc Id: ENSPPAP00000033834   ⟸   ENSPPAT00000056713
RefSeq Acc Id: ENSPPAP00000033842   ⟸   ENSPPAT00000056721
RefSeq Acc Id: ENSPPAP00000033849   ⟸   ENSPPAT00000056728
RefSeq Acc Id: XP_057158970   ⟸   XM_057302987
- Peptide Label: isoform X1
Protein Domains
BRICHOS


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000039784 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000056702.1 UniProtKB/TrEMBL
  ENSPPAT00000056713.1 UniProtKB/TrEMBL
  ENSPPAT00000056721.1 UniProtKB/TrEMBL
  ENSPPAT00000056728.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.390.150 UniProtKB/TrEMBL
InterPro BRICHOS_dom UniProtKB/TrEMBL
  SP-C UniProtKB/TrEMBL
  SP-C_palmitoylation_site UniProtKB/TrEMBL
  Surfactant_protein_propep UniProtKB/TrEMBL
KEGG Report pps:100980096 UniProtKB/TrEMBL
NCBI Gene SFTPC ENTREZGENE
PANTHER PTHR10800 UniProtKB/TrEMBL
  PULMONARY SURFACTANT-ASSOCIATED PROTEIN C UniProtKB/TrEMBL
Pfam BRICHOS UniProtKB/TrEMBL
  SP_C-Propep UniProtKB/TrEMBL
PROSITE BRICHOS UniProtKB/TrEMBL
  SURFACT_PALMITOYL UniProtKB/TrEMBL
SMART BRICHOS UniProtKB/TrEMBL
  SF_P UniProtKB/TrEMBL
UniProt A0A2R9BVW5_PANPA UniProtKB/TrEMBL
  A0A2R9BVX8_PANPA UniProtKB/TrEMBL
  A0A2R9C5L9 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C5N4_PANPA UniProtKB/TrEMBL