FKBP4 (FKBP prolyl isomerase 4) - Rat Genome Database

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Gene: FKBP4 (FKBP prolyl isomerase 4) Pan paniscus
Analyze
Symbol: FKBP4
Name: FKBP prolyl isomerase 4
RGD ID: 11801926
Description: ENCODES a protein that exhibits ATP binding (ortholog); copper-dependent protein binding (ortholog); GTP binding (ortholog); INVOLVED IN androgen receptor signaling pathway (ortholog); copper ion transport (ortholog); embryo implantation (ortholog); PARTICIPATES IN aldosterone signaling pathway; cortisol signaling pathway; estrogen signaling pathway; ASSOCIATED WITH androgen insensitivity syndrome (ortholog); genetic disease (ortholog); Hyperphosphatemic Familial Tumoral Calcinosis 1 (ortholog); FOUND IN axonal growth cone (ortholog); neuronal cell body (ortholog); perinuclear region of cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FK506 binding protein 4; peptidyl-prolyl cis-trans isomerase FKBP4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2108,341,673 - 8,353,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,338,572 - 8,350,663 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,915,017 - 2,924,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,847,333 - 2,856,118 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,847,496 - 2,856,107 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
FKBP4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2108,341,673 - 8,353,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1128,338,572 - 8,350,663 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0122,915,017 - 2,924,423 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1122,847,333 - 2,856,118 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl122,847,496 - 2,856,107 (+)Ensemblpanpan1.1panPan2
FKBP4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38122,794,970 - 2,805,423 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl122,794,970 - 2,805,423 (+)EnsemblGRCh38hg38GRCh38
GRCh37122,904,136 - 2,914,589 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36122,774,414 - 2,783,385 (+)NCBINCBI36Build 36hg18NCBI36
Build 34122,774,413 - 2,783,383NCBI
Celera124,518,032 - 4,528,525 (+)NCBICelera
Cytogenetic Map12p13.33NCBI
HuRef122,762,075 - 2,772,155 (+)NCBIHuRef
CHM1_1122,903,346 - 2,913,827 (+)NCBICHM1_1
T2T-CHM13v2.0122,800,969 - 2,811,423 (+)NCBIT2T-CHM13v2.0
Fkbp4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396128,407,066 - 128,415,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6128,406,698 - 128,415,640 (-)EnsemblGRCm39 Ensembl
GRCm386128,430,103 - 128,438,656 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6128,429,735 - 128,438,677 (-)EnsemblGRCm38mm10GRCm38
MGSCv376128,380,125 - 128,388,649 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366128,395,726 - 128,404,250 (-)NCBIMGSCv36mm8
Celera6130,106,929 - 130,115,449 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.0NCBI
Fkbp4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84163,389,464 - 163,397,918 (-)NCBIGRCr8
mRatBN7.24161,703,379 - 161,711,833 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4161,703,379 - 161,711,833 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4167,932,996 - 167,941,451 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04163,715,934 - 163,724,389 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04162,349,970 - 162,358,425 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04161,748,993 - 161,757,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4161,748,993 - 161,757,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04226,954,534 - 226,962,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44165,448,027 - 165,456,481 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14165,694,232 - 165,699,379 (-)NCBI
Celera4150,404,805 - 150,413,259 (-)NCBICelera
Cytogenetic Map4q42NCBI
Fkbp4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542918,334,939 - 18,344,530 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542918,334,939 - 18,344,530 (+)NCBIChiLan1.0ChiLan1.0
FKBP4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12741,950,087 - 41,959,136 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2741,950,509 - 41,959,034 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha274,725,111 - 4,734,083 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02742,308,268 - 42,317,245 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2742,308,301 - 42,317,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12742,249,772 - 42,258,704 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02742,219,464 - 42,228,431 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0274,084,855 - 4,093,764 (+)NCBIUU_Cfam_GSD_1.0
Fkbp4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945106,052,813 - 106,061,344 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366063,122,736 - 3,134,823 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366063,122,798 - 3,131,352 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKBP4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl567,313,480 - 67,322,028 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1567,314,010 - 67,321,628 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2569,600,337 - 69,607,970 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FKBP4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1112,860,932 - 2,869,885 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl112,860,935 - 2,870,383 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660635,446,823 - 5,455,813 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkbp4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624860122,208 - 134,415 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624860122,728 - 135,258 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034935179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSPPAT00000009035   ⟹   ENSPPAP00000001816
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl122,847,496 - 2,855,434 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000009087   ⟹   ENSPPAP00000001825
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl122,849,178 - 2,856,107 (+)Ensembl
RefSeq Acc Id: XM_034935179   ⟹   XP_034791070
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2108,341,673 - 8,353,904 (+)NCBI
NHGRI_mPanPan1128,338,572 - 8,350,663 (+)NCBI
Mhudiblu_PPA_v0122,915,017 - 2,924,423 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034791070 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000001816.1
  ENSPPAP00000001825.1
RefSeq Acc Id: XP_034791070   ⟸   XM_034935179
- UniProtKB: A0A2R8Z9Y0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000001825   ⟸   ENSPPAT00000009087
RefSeq Acc Id: ENSPPAP00000001816   ⟸   ENSPPAT00000009035
Protein Domains
PPIase FKBP-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000008207 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000009035.1 UniProtKB/TrEMBL
  ENSPPAT00000009087.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  3.10.50.40 UniProtKB/TrEMBL
InterPro PPIase_dom_sf UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_1 UniProtKB/TrEMBL
  TPR_2 UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
NCBI Gene FKBP4 ENTREZGENE
PANTHER PEPTIDYLPROLYL ISOMERASE UniProtKB/TrEMBL
  PEPTIDYLPROLYL ISOMERASE UniProtKB/TrEMBL
Pfam FKBP_C UniProtKB/TrEMBL
  TPR_1 UniProtKB/TrEMBL
  TPR_2 UniProtKB/TrEMBL
PROSITE FKBP_PPIASE UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
SMART TPR UniProtKB/TrEMBL
Superfamily-SCOP FKBP-like UniProtKB/TrEMBL
  SSF48452 UniProtKB/TrEMBL
UniProt A0A2R8Z9Y0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z9Y7_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-06 FKBP4  FKBP prolyl isomerase 4    FK506 binding protein 4  Symbol and/or name change 5135510 APPROVED