MRS2 (magnesium transporter MRS2) - Rat Genome Database

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Gene: MRS2 (magnesium transporter MRS2) Pan paniscus
Analyze
Symbol: MRS2
Name: magnesium transporter MRS2
RGD ID: 11786090
Description: ENCODES a protein that exhibits magnesium ion transmembrane transporter activity (inferred); INVOLVED IN lactate metabolic process (ortholog); ASSOCIATED WITH demyelinating disease (ortholog); genetic disease (ortholog); succinic semialdehyde dehydrogenase deficiency (ortholog); FOUND IN mitochondrial inner membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: magnesium transporter MRS2 homolog, mitochondrial; MRS2 magnesium homeostasis factor homolog; MRS2, magnesium transporter
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,045,947 - 39,068,735 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,045,445 - 35,066,904 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,232,576 - 24,255,890 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,566,188 - 24,587,095 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,566,188 - 24,586,527 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
MRS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2539,045,947 - 39,068,735 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1635,045,445 - 35,066,904 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0624,232,576 - 24,255,890 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1624,566,188 - 24,587,095 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl624,566,188 - 24,586,527 (+)Ensemblpanpan1.1panPan2
MRS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38624,402,936 - 24,426,190 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl624,402,908 - 24,426,194 (+)EnsemblGRCh38hg38GRCh38
GRCh37624,403,164 - 24,426,418 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36624,511,132 - 24,533,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 34624,511,160 - 24,532,469NCBI
Celera625,636,588 - 25,659,248 (+)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef624,352,376 - 24,375,039 (+)NCBIHuRef
CHM1_1624,407,390 - 24,430,051 (+)NCBICHM1_1
T2T-CHM13v2.0624,272,971 - 24,296,223 (+)NCBIT2T-CHM13v2.0
Mrs2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391325,171,466 - 25,204,345 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1325,171,466 - 25,204,362 (-)EnsemblGRCm39 Ensembl
GRCm381324,987,483 - 25,020,363 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1324,987,483 - 25,020,379 (-)EnsemblGRCm38mm10GRCm38
MGSCv371325,084,352 - 25,112,248 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361324,999,948 - 25,027,844 (-)NCBIMGSCv36mm8
Celera1325,223,152 - 25,251,336 (-)NCBICelera
Cytogenetic Map13A3.1NCBI
cM Map1310.83NCBI
Mrs2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81740,491,963 - 40,515,116 (+)NCBIGRCr8
mRatBN7.21740,063,924 - 40,087,073 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1740,063,962 - 40,081,887 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1740,132,120 - 40,149,974 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01741,736,172 - 41,754,026 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01740,017,602 - 40,035,452 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01742,064,271 - 42,083,602 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1742,064,376 - 42,082,300 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01743,932,146 - 43,951,399 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41747,124,915 - 47,142,840 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11747,127,755 - 47,145,681 (+)NCBI
Celera1739,701,559 - 39,719,484 (+)NCBICelera
Cytogenetic Map17p11NCBI
Mrs2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554832,555,355 - 2,569,544 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554832,555,355 - 2,569,543 (-)NCBIChiLan1.0ChiLan1.0
MRS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13522,460,435 - 22,496,064 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3522,459,436 - 22,492,543 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3522,426,719 - 22,461,618 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03522,580,374 - 22,615,640 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3522,580,299 - 22,615,634 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13522,385,891 - 22,421,114 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03522,434,397 - 22,469,435 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03523,870,024 - 23,905,308 (+)NCBIUU_Cfam_GSD_1.0
Mrs2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049462,841,835 - 2,859,468 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936671761,071 - 779,713 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936671761,071 - 779,713 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MRS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl719,244,661 - 19,291,531 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1719,244,607 - 19,295,483 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2720,394,720 - 20,442,106 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MRS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11747,811,801 - 47,831,675 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1747,814,306 - 47,831,629 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604424,341,219 - 24,361,002 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mrs2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247562,574,588 - 2,600,533 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247562,572,218 - 2,600,464 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000046273   ⟹   ENSPPAP00000023448
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl624,566,188 - 24,586,527 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000046276   ⟹   ENSPPAP00000023451
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl624,566,188 - 24,586,527 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000046281   ⟹   ENSPPAP00000023456
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl624,566,188 - 24,586,527 (+)Ensembl
RefSeq Acc Id: XM_034961541   ⟹   XP_034817432
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2539,045,947 - 39,068,735 (+)NCBI
NHGRI_mPanPan1635,045,445 - 35,066,904 (+)NCBI
Mhudiblu_PPA_v0624,232,576 - 24,255,890 (+)NCBI
RefSeq Acc Id: XM_034961542   ⟹   XP_034817433
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2539,045,968 - 39,068,735 (+)NCBI
NHGRI_mPanPan1635,045,455 - 35,066,904 (+)NCBI
Mhudiblu_PPA_v0624,232,576 - 24,255,890 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034817432 (Get FASTA)   NCBI Sequence Viewer  
  XP_034817433 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000023448.1
  ENSPPAP00000023451.1
  ENSPPAP00000023456.1
Reference Protein Sequences
RefSeq Acc Id: XP_034817432   ⟸   XM_034961541
- Peptide Label: isoform X1
- UniProtKB: A0A2R9B5G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034817433   ⟸   XM_034961542
- Peptide Label: isoform X2
- UniProtKB: A0A2R9B1P0 (UniProtKB/TrEMBL),   A0A2R9B5G7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000023448   ⟸   ENSPPAT00000046273
RefSeq Acc Id: ENSPPAP00000023451   ⟸   ENSPPAT00000046276
RefSeq Acc Id: ENSPPAP00000023456   ⟸   ENSPPAT00000046281


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000034886 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000046273.1 UniProtKB/TrEMBL
  ENSPPAT00000046276.1 UniProtKB/TrEMBL
  ENSPPAT00000046281.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.128.330 UniProtKB/TrEMBL
  Magnesium transport protein CorA, transmembrane region UniProtKB/TrEMBL
InterPro MRS2-like UniProtKB/TrEMBL
NCBI Gene MRS2 ENTREZGENE
PANTHER MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL UniProtKB/TrEMBL
  PTHR13890 UniProtKB/TrEMBL
UniProt A0A2R9B1P0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B1P4_PANPA UniProtKB/TrEMBL
  A0A2R9B5G7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-21 MRS2  magnesium transporter MRS2    MRS2, magnesium transporter  Symbol and/or name change 5135510 APPROVED