CDK2 (cyclin dependent kinase 2) - Rat Genome Database

Name: CDK2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: CDK2 (cyclin dependent kinase 2) Pan paniscus

Analyze

Symbol:

CDK2

Name:

cyclin dependent kinase 2

RGD ID:

11785959

Description:

ENCODES a protein that exhibits cyclin binding (ortholog); cyclin-dependent protein serine/threonine kinase activity (ortholog); histone kinase activity (ortholog); INVOLVED IN animal organ regeneration (ortholog); cellular response to insulin stimulus (ortholog); DNA damage response (ortholog); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; ASSOCIATED WITH breast cancer (ortholog); Embryo Loss (ortholog); Endometrial Neoplasms (ortholog); FOUND IN cyclin A2-CDK2 complex (ortholog); cyclin E1-CDK2 complex (ortholog); cyclin E2-CDK2 complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

cyclin-dependent kinase 2

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	38,353,674 - 38,359,695 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,236 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	33,189,934 - 33,195,945 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	33,189,934 - 33,195,945 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

breast cancer (ISO)

Embryo Loss (ISO)

Endometrial Neoplasms (ISO)

Endometrioid Carcinomas (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Mammary Neoplasms (ISO)

genetic disease (ISO)

Habitual Abortions (ISO)

head and neck squamous cell carcinoma (ISO)

Intimal Hyperplasia (ISO)

melanoma (ISO)

membranoproliferative glomerulonephritis (ISO)

Optic Nerve Injuries (ISO)

Ovarian Neoplasms (ISO)

prostate cancer (ISO)

renal cell carcinoma (ISO)

Triple Negative Breast Neoplasms (ISO)

Uterine Cervical Neoplasms (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ regeneration (ISO)

cellular response to insulin stimulus (ISO)

centriole replication (IEA)

chromatin remodeling (IEA)

DNA damage response (ISO)

DNA repair (IEA)

DNA-templated transcription (IEA,ISO)

G1/S transition of mitotic cell cycle (IEA,ISO)

lens development in camera-type eye (ISO)

negative regulation of protein catabolic process (ISO)

negative regulation of transcription by RNA polymerase II (IEA,ISO)

positive regulation of cell population proliferation (IEA)

positive regulation of DNA-templated DNA replication initiation (IEA,ISO)

positive regulation of DNA-templated transcription (IEA,ISO)

positive regulation of heterochromatin formation (IEA)

positive regulation of meiotic cell cycle process involved in oocyte maturation (ISO)

post-translational protein modification (IEA)

potassium ion transport (IEA,ISO)

Ras protein signal transduction (IEA)

regulation of G2/M transition of mitotic cell cycle (IEA)

regulation of gene expression (IEA)

response to cadmium ion (ISO)

response to cAMP (ISO)

response to electrical stimulus (ISO)

response to estradiol (ISO)

response to ethanol (ISO)

response to toxic substance (ISO)

response to xenobiotic stimulus (ISO)

signal transduction (IEA)

telomere maintenance in response to DNA damage (ISO)

Cellular Component

Cajal body (IEA)

centrosome (IEA)

chromosome, telomeric region (IEA)

condensed chromosome (IEA)

cyclin A1-CDK2 complex (IEA)

cyclin A2-CDK2 complex (IEA,ISO)

cyclin E1-CDK2 complex (IEA,ISO)

cyclin E2-CDK2 complex (IEA,ISO)

cyclin-dependent protein kinase holoenzyme complex (IEA)

cytoplasm (IEA)

endosome (IEA)

male germ cell nucleus (IEA)

nuclear envelope (IEA)

nucleoplasm (IEA)

nucleus (IEA)

transcription regulator complex (IEA)

X chromosome (IEA)

Y chromosome (IEA)

Molecular Function

ATP binding (IEA)

cyclin binding (IEA,ISO)

cyclin-dependent protein kinase activity (IEA)

cyclin-dependent protein serine/threonine kinase activity (IEA,ISO)

histone kinase activity (IEA,ISO)

kinase activity (IEA)

magnesium ion binding (IEA)

protein binding (ISO)

protein domain specific binding (IEA)

protein kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

protein-containing complex binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

G1/S transition pathway (ISO)

interleukin-2 signaling pathway (ISO)

mTOR signaling pathway (ISO)

p53 signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

CDK2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	38,353,674 - 38,359,695 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,236 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	33,189,934 - 33,195,945 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	33,189,934 - 33,195,945 (-)	Ensembl	panpan1.1		panPan2

CDK2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	55,966,830 - 55,972,789 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	55,966,781 - 55,972,789 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	56,360,614 - 56,366,573 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	54,646,826 - 54,652,835 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	54,646,825 - 54,652,834	NCBI
Celera	12	56,013,264 - 56,019,276 (+)	NCBI		Celera
Cytogenetic Map	12	q13.2	NCBI
HuRef	12	53,399,466 - 53,405,479 (+)	NCBI		HuRef
CHM1_1	12	56,327,689 - 56,333,679 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	55,933,893 - 55,939,852 (+)	NCBI		T2T-CHM13v2.0

Cdk2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	128,533,807 - 128,540,920 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	128,533,808 - 128,540,900 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	128,697,938 - 128,705,051 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	128,697,939 - 128,705,031 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	128,134,995 - 128,142,107 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	128,100,888 - 128,107,961 (-)	NCBI		MGSCv36	mm8
Celera	10	131,090,071 - 131,097,183 (-)	NCBI		Celera
Cytogenetic Map	10	D3	NCBI
cM Map	10	77.13	NCBI

Cdk2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	1,714,392 - 1,721,964 (-)	NCBI		GRCr8
mRatBN7.2	7	1,129,878 - 1,137,431 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	1,129,811 - 1,137,403 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	3,893,030 - 3,900,519 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	5,768,702 - 5,776,191 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	6,065,517 - 6,073,007 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	3,124,953 - 3,132,533 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	3,124,954 - 3,132,457 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	3,097,653 - 3,105,210 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	2,000,196 - 2,007,682 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	2,000,196 - 2,007,682 (-)	NCBI
Celera	7	1,000,083 - 1,007,560 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Cdk2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955458	3,555,603 - 3,562,120 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955458	3,555,603 - 3,561,063 (+)	NCBI	ChiLan1.0	ChiLan1.0

CDK2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	300,863 - 306,546 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	300,903 - 305,438 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	362,779 - 368,479 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	307,657 - 313,366 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	307,694 - 312,540 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	285,465 - 291,170 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	528,243 - 533,942 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	652,514 - 658,220 (+)	NCBI		UU_Cfam_GSD_1.0

Cdk2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	58,484,370 - 58,490,389 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936646	379,842 - 385,877 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936646	379,849 - 385,648 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDK2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	21,365,764 - 21,372,168 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	21,365,723 - 21,372,170 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	22,941,174 - 22,947,591 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDK2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	51,905,085 - 51,910,209 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	51,905,115 - 51,909,907 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	194,076,082 - 194,082,105 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdk2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624802	12,076,443 - 12,082,630 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624802	12,076,443 - 12,082,608 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003824947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008978640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034935689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095558	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055095559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSPPAT00000045861 ⟹ ENSPPAP00000023043

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	33,189,934 - 33,195,945 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000045882 ⟹ ENSPPAP00000023062

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	33,191,098 - 33,195,705 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000045884 ⟹ ENSPPAP00000023065

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	33,191,098 - 33,195,705 (-)	Ensembl

RefSeq Acc Id:

ENSPPAT00000045887 ⟹ ENSPPAP00000023067

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	12	33,191,098 - 33,195,705 (-)	Ensembl

RefSeq Acc Id:

XM_003824947 ⟹ XP_003824995

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,945 (-)	NCBI
NHGRI_mPanPan1	12	38,353,674 - 38,359,695 (-)	NCBI
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,233 (-)	NCBI
PanPan1.1	12	33,189,934 - 33,195,945 (-)	NCBI

Sequence:

show sequence

AACGCGGGAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGTAACATT
GTTTCAAGTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCA
CGGTACTGGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTT
CCCAGGCCCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAA
AGGTGGAAAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGG
AGAAGTGGTGGCGCTTAAGAAAATCCGCCTGGACACTGAGACTGAGGGTGTGCCCAGTACTGCC
ATCCGAGAGATCTCTCTGCTTAAGGAGCTTAACCATCCTAATATTGTCAAGCTGCTGGATGTCA
TTCACACAGAAAATAAACTCTACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCAT
GGATGCCTCTGCTCTCACTGGCATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTC
CAGGGCCTAGCTTTCTGCCATTCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGC
TTATTAACACAGAGGGGGCCATCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCC
TGTTCGTACTTACACCCATGAGGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGC
TGCAAATATTATTCCACAGCTGTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGGTGA
CTCGCCGGGCCCTATTCCCTGGAGATTCTGAGATTGACCAGCTCTTCCGGATCTTTCGGACTCT
GGGGACCCCAGATGAGGTGGTGTGGCCAGGAGTTACTTCTATGCCTGATTACAAGCCAAGTTTC
CCCAAGTGGGCCCGGCAAGATTTTAGTAAAGTTGTACCTCCCCTGGATGAAGATGGACGGAGCT
TGTTATCGCAAATGCTGCACTACGACCCTAACAAGCGGATTTCGGCCAAGGCAGCCCTGGCTCA
CCCTTTCTTCCAGGATGTGACCAAGCCAGTACCCCATCTTCGACTCTGATAGCCTTCTTGAAGC
CCCCAGCCCTAATCTCACCCTCTCCTCCAGTGTGGGCTTGACCAGGCTTGGCCTTGGGCTATTT
GGACTCAGGTGGGCCCTCTGATCTTGCCTTAAACACTCACCTTCTAGTCTTGGCCAGCCAACTC
TGGGAATACAGGGGTGAAAGGGGGGAACCAGTGAAAATGAAAGGAAGTTTCAGTATTAGATGCA
CTTAAGTTAGCCTCCACCACCCTTTCCCCCTTCTCTTAGTTATTGCTGAAGAGGGTTGGTATAA
AAATAATTTTAAAAAAGCCTTCCTACACGTTAGATTTGCCGTACCAATCTCTGAATGCCCCATA
ATTATTATTTCCAGTGTTTGGGATGACCAGGATCCCAAGCCTCCTGCTGCCACAATGTTTATAA
AGGCCAAATGATAGCAGGGGCTAAGTTGGTGCTTTTGAGAACCAAGTAAAACAAAACCACTGGG
AGGAGTCTATTTTAAAGAATTCGGTTGAAAAAATAGATCCAATCAGTTTATACCCTAGTTAGTG
TTTTGCCTCACCTAATAGGCTGGAGACTGAAGACTCAGCCCGGGTGGGGCTGCAGAAAAATGAT
TGGCCCCAGTCCCCTTGTTTGTCCCTTCTACAGGCATGAGGAATCTGGGAGGCCCTGGGACAGG
GATTATGCTTCATTCCAATCTATTGCTTCACCATGGCCTTATGAGGCAGGTGAGAGATGTTTGA
ATTTTTCTCTTCCTTTTAGTATTCTTAGTTCTTCAGTTGCCAAGGATCCCTGATCCCATTTTCC
TCTGAAGTCCACCTCCTACCCCATAGGAGTTAGAAGTTAGGGTTTAGGCATCATTTTGAGAATG
CTGACACTTTTTCAGGGCTGTGATTGAGTGAGGGCATGGGTAAAAATATTTCTTTAAAAGAAGG
ATGAACAATTATATTTATATTTCAGGTTATATCCAATAGTAGAGTTGGCTTTTTTTTTTTTTGG
TCATAGTGGGTGGATTTGTTGCCATGTGCACCTTGGGGTTTTGTAATGACAGTGCTAAAAAAAA
AAAGCATTTTTTTGTTTGTTTATGATTTGTCTCTGTCACCCTTGTCCTTGAGTGCTCTTGCTAT
TAACGTTATTTGTAATTTAGTTTGTAGCTCATTAAAAAAATGTGCCTAGTTTTATAGTTCA

hide sequence

RefSeq Acc Id:

XM_008978640 ⟹ XP_008976888

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,955 (-)	NCBI
NHGRI_mPanPan1	12	38,353,674 - 38,359,663 (-)	NCBI
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,234 (-)	NCBI
PanPan1.1	12	33,189,934 - 33,195,938 (-)	NCBI

Sequence:

show sequence

GAAGCAGGGGCGGGGCCTCTGGTGGCGGTCGGGAACTCGGTGGGAGGCGGTAACATTGTTTCAA
GTTGGCCAAATTGACAAGAGCGAGAGGTATACTGCGTTCCATCCCGACCCGGGGCCACGGTACT
GGGCCCTGTTTCCCCCTCCTCGGCCCCCGAGAGCCAGGGTCCGCCTTCTGCAGGGTTCCCAGGC
CCCCGCTCCAGGGCCGGGCTGACCCGACTCGCTGGCGCTTCATGGAGAACTTCCAAAAGGTGGA
AAAGATCGGAGAGGGCACGTACGGAGTTGTGTACAAAGCCAGAAACAAGTTGACGGGAGAAGTG
GTGGCGCTTAAGAAAATCCGCCTGGACACGCTGCTGGATGTCATTCACACAGAAAATAAACTCT
ACCTGGTTTTTGAATTTCTGCACCAAGATCTCAAGAAATTCATGGATGCCTCTGCTCTCACTGG
CATTCCTCTTCCCCTCATCAAGAGCTATCTGTTCCAGCTGCTCCAGGGCCTAGCTTTCTGCCAT
TCTCATCGGGTCCTCCACCGAGACCTTAAACCTCAGAATCTGCTTATTAACACAGAGGGGGCCA
TCAAGCTAGCAGACTTTGGACTAGCCAGAGCTTTTGGAGTCCCTGTTCGTACTTACACCCATGA
GGTGGTGACCCTGTGGTACCGAGCTCCTGAAATCCTCCTGGGCTGCAAATATTATTCCACAGCT
GTGGACATCTGGAGCCTGGGCTGCATCTTTGCTGAGATGGTGACTCGCCGGGCCCTATTCCCTG
GAGATTCTGAGATTGACCAGCTCTTCCGGATCTTTCGGACTCTGGGGACCCCAGATGAGGTGGT
GTGGCCAGGAGTTACTTCTATGCCTGATTACAAGCCAAGTTTCCCCAAGTGGGCCCGGCAAGAT
TTTAGTAAAGTTGTACCTCCCCTGGATGAAGATGGACGGAGCTTGTTATCGCAAATGCTGCACT
ACGACCCTAACAAGCGGATTTCGGCCAAGGCAGCCCTGGCTCACCCTTTCTTCCAGGATGTGAC
CAAGCCAGTACCCCATCTTCGACTCTGATAGCCTTCTTGAAGCCCCCAGCCCTAATCTCACCCT
CTCCTCCAGTGTGGGCTTGACCAGGCTTGGCCTTGGGCTATTTGGACTCAGGTGGGCCCTCTGA
TCTTGCCTTAAACACTCACCTTCTAGTCTTGGCCAGCCAACTCTGGGAATACAGGGGTGAAAGG
GGGGAACCAGTGAAAATGAAAGGAAGTTTCAGTATTAGATGCACTTAAGTTAGCCTCCACCACC
CTTTCCCCCTTCTCTTAGTTATTGCTGAAGAGGGTTGGTATAAAAATAATTTTAAAAAAGCCTT
CCTACACGTTAGATTTGCCGTACCAATCTCTGAATGCCCCATAATTATTATTTCCAGTGTTTGG
GATGACCAGGATCCCAAGCCTCCTGCTGCCACAATGTTTATAAAGGCCAAATGATAGCAGGGGC
TAAGTTGGTGCTTTTGAGAACCAAGTAAAACAAAACCACTGGGAGGAGTCTATTTTAAAGAATT
CGGTTGAAAAAATAGATCCAATCAGTTTATACCCTAGTTAGTGTTTTGCCTCACCTAATAGGCT
GGAGACTGAAGACTCAGCCCGGGTGGGGCTGCAGAAAAATGATTGGCCCCAGTCCCCTTGTTTG
TCCCTTCTACAGGCATGAGGAATCTGGGAGGCCCTGGGACAGGGATTATGCTTCATTCCAATCT
ATTGCTTCACCATGGCCTTATGAGGCAGGTGAGAGATGTTTGAATTTTTCTCTTCCTTTTAGTA
TTCTTAGTTCTTCAGTTGCCAAGGATCCCTGATCCCATTTTCCTCTGAAGTCCACCTCCTACCC
CATAGGAGTTAGAAGTTAGGGTTTAGGCATCATTTTGAGAATGCTGACACTTTTTCAGGGCTGT
GATTGAGTGAGGGCATGGGTAAAAATATTTCTTTAAAAGAAGGATGAACAATTATATTTATATT
TCAGGTTATATCCAATAGTAGAGTTGGCTTTTTTTTTTTTTGGTCATAGTGGGTGGATTTGTTG
CCATGTGCACCTTGGGGTTTTGTAATGACAGTGCTAAAAAAAAAAAGCATTTTTTTGTTTGTTT
ATGATTTGTCTCTGTCACCCTTGTCCTTGAGTGCTCTTGCTATTAACGTTATTTGTAATTTAGT
TTGTAGCTCATTAAAAAAATGTGCCTAGTTTTATAGTTCA

hide sequence

RefSeq Acc Id:

XM_034935689 ⟹ XP_034791580

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI
NHGRI_mPanPan1	12	38,353,674 - 38,359,660 (-)	NCBI
Mhudiblu_PPA_v0	12	32,940,225 - 32,946,236 (-)	NCBI

RefSeq Acc Id:

XM_055095558 ⟹ XP_054951533

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,957 (-)	NCBI
NHGRI_mPanPan1	12	38,353,674 - 38,359,660 (-)	NCBI

RefSeq Acc Id:

XM_055095559 ⟹ XP_054951534

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	10	38,356,902 - 38,362,969 (-)	NCBI
NHGRI_mPanPan1	12	38,353,674 - 38,359,660 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003824995	(Get FASTA)	NCBI Sequence Viewer
	XP_008976888	(Get FASTA)	NCBI Sequence Viewer
	XP_034791580	(Get FASTA)	NCBI Sequence Viewer
	XP_054951533	(Get FASTA)	NCBI Sequence Viewer
	XP_054951534	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000023043
	ENSPPAP00000023043.1
	ENSPPAP00000023062.1
	ENSPPAP00000023065.1
	ENSPPAP00000023067
	ENSPPAP00000023067.1

RefSeq Acc Id:	XP_003824995 ⟸ XM_003824947
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9B4E4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIV KLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDL KPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCI FAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLD EDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL hide sequence

RefSeq Acc Id:

XP_008976888 ⟸ XM_008978640

- Peptide Label:

isoform X2

- Sequence:

show sequence

MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTLLDVIHTENKLYLVFEFLHQDLKKF
MDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGV
PVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRT
LGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALA
HPFFQDVTKPVPHLRL

hide sequence

RefSeq Acc Id:	XP_034791580 ⟸ XM_034935689
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9B6W1 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSPPAP00000023043 ⟸ ENSPPAT00000045861

RefSeq Acc Id:

ENSPPAP00000023067 ⟸ ENSPPAT00000045887

RefSeq Acc Id:

ENSPPAP00000023065 ⟸ ENSPPAT00000045884

RefSeq Acc Id:

ENSPPAP00000023062 ⟸ ENSPPAT00000045882

RefSeq Acc Id:	XP_054951534 ⟸ XM_055095559
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9B6W4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054951533 ⟸ XM_055095558
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9B0D1 (UniProtKB/TrEMBL)

Protein Domains

Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000034672	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000045861.1	UniProtKB/TrEMBL
	ENSPPAT00000045882.1	UniProtKB/TrEMBL
	ENSPPAT00000045884.1	UniProtKB/TrEMBL
	ENSPPAT00000045887.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/TrEMBL
KEGG Report	pps:100981695	UniProtKB/TrEMBL
NCBI Gene	CDK2	ENTREZGENE
PANTHER	CELL DIVISION PROTEIN KINASE	UniProtKB/TrEMBL
	CYCLIN-DEPENDENT KINASE 2	UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/TrEMBL
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9B0D1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B4E4	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B6W1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9B6W4	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)