ADAMTS19 (ADAM metallopeptidase with thrombospondin type 1 motif 19) - Rat Genome Database

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Gene: ADAMTS19 (ADAM metallopeptidase with thrombospondin type 1 motif 19) Pan paniscus
Analyze
Symbol: ADAMTS19
Name: ADAM metallopeptidase with thrombospondin type 1 motif 19
RGD ID: 11779979
Description: ENCODES a protein that exhibits metal ion binding (inferred); metalloendopeptidase activity (inferred); metallopeptidase activity (inferred); INVOLVED IN mitral valve morphogenesis (ortholog); pulmonary valve morphogenesis (ortholog); tricuspid valve morphogenesis (ortholog); ASSOCIATED WITH aortic valve disease (ortholog); CARDIAC VALVULAR DYSPLASIA 2 (ortholog); familial adenomatous polyposis 1 (ortholog); FOUND IN extracellular matrix (inferred); extracellular region (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: A disintegrin and metalloproteinase with thrombospondin motifs 19
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24124,768,335 - 125,048,879 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15122,907,899 - 123,188,487 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05124,873,078 - 125,153,730 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15130,635,617 - 131,325,426 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5130,635,937 - 130,893,174 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ADAMTS19
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24124,768,335 - 125,048,879 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15122,907,899 - 123,188,487 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05124,873,078 - 125,153,730 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15130,635,617 - 131,325,426 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5130,635,937 - 130,893,174 (+)Ensemblpanpan1.1panPan2
ADAMTS19
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385129,460,298 - 129,738,683 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5129,460,281 - 129,738,683 (+)EnsemblGRCh38hg38GRCh38
GRCh375128,795,991 - 129,074,376 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365128,824,002 - 129,102,275 (+)NCBINCBI36Build 36hg18NCBI36
Build 345128,824,001 - 129,100,971NCBI
Celera5124,927,090 - 125,204,740 (+)NCBICelera
Cytogenetic Map5q23.3NCBI
HuRef5123,988,310 - 124,266,072 (+)NCBIHuRef
CHM1_15128,228,804 - 128,506,974 (+)NCBICHM1_1
T2T-CHM13v2.05129,978,934 - 130,257,460 (+)NCBIT2T-CHM13v2.0
Adamts19
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391858,967,819 - 59,186,754 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1858,969,739 - 59,187,132 (+)EnsemblGRCm39 Ensembl
GRCm381858,835,992 - 59,053,682 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1858,836,667 - 59,054,060 (+)EnsemblGRCm38mm10GRCm38
MGSCv371858,996,418 - 59,213,332 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361858,962,133 - 59,179,047 (+)NCBIMGSCv36mm8
Celera1860,148,256 - 60,359,984 (+)NCBICelera
Cytogenetic Map18D3NCBI
cM Map1833.78NCBI
Adamts19
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81854,545,357 - 54,729,184 (+)NCBIGRCr8
mRatBN7.21852,346,448 - 52,531,245 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1852,347,428 - 52,530,509 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1854,374,302 - 54,558,621 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01855,088,882 - 55,273,203 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01852,898,078 - 53,081,916 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01853,915,807 - 54,099,856 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1853,915,807 - 54,099,120 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01853,154,607 - 53,337,829 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41854,660,288 - 54,847,297 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11854,731,987 - 54,919,282 (+)NCBI
Celera1850,452,348 - 50,634,623 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
Adamts19
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554152,384,530 - 2,617,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554152,384,530 - 2,617,454 (+)NCBIChiLan1.0ChiLan1.0
ADAMTS19
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11118,272,602 - 18,500,581 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1118,272,412 - 18,499,496 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1117,072,306 - 17,300,168 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01119,039,211 - 19,255,681 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1119,027,000 - 19,254,767 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11117,747,255 - 17,980,124 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01117,585,712 - 17,814,466 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01118,199,198 - 18,428,137 (+)NCBIUU_Cfam_GSD_1.0
Adamts19
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213140,993,422 - 141,249,059 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365042,567,552 - 2,821,576 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365042,567,433 - 2,823,087 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAMTS19
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2132,145,310 - 132,409,915 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12132,145,266 - 132,413,116 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22137,454,237 - 137,675,689 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAMTS19
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12332,372,312 - 32,646,070 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2332,372,515 - 32,646,071 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603445,363,958 - 45,650,817 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adamts19
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477411,631,376 - 11,900,121 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477411,631,446 - 11,900,692 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000035548   ⟹   ENSPPAP00000012881
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl5130,635,937 - 130,893,174 (+)Ensembl
RefSeq Acc Id: XM_014344971   ⟹   XP_014200457
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24124,768,335 - 125,048,879 (+)NCBI
NHGRI_mPanPan15122,907,899 - 123,188,487 (+)NCBI
Mhudiblu_PPA_v05124,873,078 - 125,153,730 (+)NCBI
PanPan1.15130,635,617 - 131,325,420 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024928919   ⟹   XP_024784687
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24124,768,335 - 125,048,879 (+)NCBI
NHGRI_mPanPan15122,907,899 - 123,188,486 (+)NCBI
Mhudiblu_PPA_v05124,873,302 - 125,153,380 (+)NCBI
PanPan1.15130,635,808 - 131,325,426 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024928920   ⟹   XP_024784688
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v24124,768,335 - 125,048,879 (+)NCBI
NHGRI_mPanPan15122,907,899 - 123,188,484 (+)NCBI
Mhudiblu_PPA_v05124,873,078 - 125,153,730 (+)NCBI
PanPan1.15130,635,617 - 131,325,420 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_014200457 (Get FASTA)   NCBI Sequence Viewer  
  XP_024784687 (Get FASTA)   NCBI Sequence Viewer  
  XP_024784688 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000012881.1
RefSeq Acc Id: XP_014200457   ⟸   XM_014344971
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AB69 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024784688   ⟸   XM_024928920
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_024784687   ⟸   XM_024928919
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AB69 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000012881   ⟸   ENSPPAT00000035548
Protein Domains
Peptidase M12B


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000029610 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000035548.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  2.60.120.830 UniProtKB/TrEMBL
  3.40.1620.60 UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/TrEMBL
InterPro ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_Cys-rich UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  ADAMTS/ADAMTS-like UniProtKB/TrEMBL
  ADAMTS_ADAMTS-like UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene ADAMTS19 ENTREZGENE
PANTHER A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 19 UniProtKB/TrEMBL
  ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE UniProtKB/TrEMBL
Pfam ADAM_CR_2 UniProtKB/TrEMBL
  ADAM_spacer1 UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/TrEMBL
  Reprolysin UniProtKB/TrEMBL
  TSP1_ADAMTS UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS ADAMTSFAMILY UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART ACR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/TrEMBL
  SSF82895 UniProtKB/TrEMBL
UniProt A0A2R9AB69 ENTREZGENE, UniProtKB/TrEMBL