PLCD3 (phospholipase C delta 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: PLCD3 (phospholipase C delta 3) Pan paniscus
Analyze
Symbol: PLCD3
Name: phospholipase C delta 3
RGD ID: 11764476
Description: ENCODES a protein that exhibits hydrolase activity (inferred); metal ion binding (inferred); phosphatidylinositol phospholipase C activity (inferred); INVOLVED IN angiogenesis (ortholog); labyrinthine layer blood vessel development (ortholog); regulation of cell population proliferation (ortholog); PARTICIPATES IN inositol metabolic pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN nucleoplasm (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21919,704,918 - 19,725,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11721,673,497 - 21,694,350 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,194,761 - 12,215,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,370,389 - 12,391,667 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,371,299 - 12,390,691 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLCD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21919,704,918 - 19,725,778 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11721,673,497 - 21,694,350 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01712,194,761 - 12,215,615 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11712,370,389 - 12,391,667 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1712,371,299 - 12,390,691 (+)Ensemblpanpan1.1panPan2
PLCD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381745,108,959 - 45,132,515 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1745,108,959 - 45,133,354 (-)EnsemblGRCh38hg38GRCh38
GRCh371743,186,327 - 43,209,882 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361740,544,534 - 40,565,417 (-)NCBINCBI36Build 36hg18NCBI36
Build 341740,544,543 - 40,565,391NCBI
Celera1739,898,162 - 39,919,051 (-)NCBICelera
Cytogenetic Map17q21.31NCBI
HuRef1738,952,185 - 38,972,987 (-)NCBIHuRef
CHM1_11743,424,536 - 43,445,418 (-)NCBICHM1_1
T2T-CHM13v2.01745,962,835 - 45,986,399 (-)NCBIT2T-CHM13v2.0
Plcd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911102,960,062 - 102,992,484 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11102,961,130 - 102,992,484 (-)EnsemblGRCm39 Ensembl
GRCm3811103,070,296 - 103,101,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11103,070,304 - 103,101,658 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711102,931,610 - 102,962,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611102,886,400 - 102,917,692 (-)NCBIMGSCv36mm8
Celera11114,788,919 - 114,811,158 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1166.71NCBI
Plcd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81088,526,802 - 88,548,116 (-)NCBIGRCr8
mRatBN7.21088,026,707 - 88,048,080 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1088,026,740 - 88,048,296 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1093,062,952 - 93,084,281 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01092,529,623 - 92,550,923 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01087,922,965 - 87,944,272 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01091,164,778 - 91,186,067 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1091,164,812 - 91,186,054 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01090,937,117 - 90,958,001 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41092,234,651 - 92,275,433 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11092,249,509 - 92,291,067 (-)NCBI
Celera1086,728,695 - 86,749,683 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Plcd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545117,822,761 - 17,827,846 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545117,822,345 - 17,827,848 (-)NCBIChiLan1.0ChiLan1.0
PLCD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1918,399,946 - 18,419,630 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl918,400,039 - 18,419,560 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha917,784,845 - 17,804,314 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0919,073,110 - 19,092,576 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl919,073,110 - 19,092,582 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1917,951,365 - 17,970,806 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0918,130,204 - 18,149,674 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0918,286,182 - 18,305,568 (+)NCBIUU_Cfam_GSD_1.0
Plcd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560217,748,001 - 17,768,280 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365411,426,580 - 1,446,286 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365411,426,590 - 1,446,286 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1218,281,502 - 18,302,483 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11218,281,507 - 18,305,516 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,530,472 - 18,551,197 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11661,277,813 - 61,300,891 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1661,277,917 - 61,300,303 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607732,024,853 - 32,046,697 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plcd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624795270,722 - 282,390 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624795270,760 - 282,789 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000050574   ⟹   ENSPPAP00000027731
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1712,371,299 - 12,390,691 (+)Ensembl
RefSeq Acc Id: XM_034941642   ⟹   XP_034797533
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21919,704,918 - 19,725,778 (+)NCBI
NHGRI_mPanPan11721,673,497 - 21,694,350 (+)NCBI
Mhudiblu_PPA_v01712,194,761 - 12,215,615 (+)NCBI
RefSeq Acc Id: XM_034941643   ⟹   XP_034797534
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21919,704,918 - 19,725,778 (+)NCBI
NHGRI_mPanPan11721,673,497 - 21,694,350 (+)NCBI
Mhudiblu_PPA_v01712,194,761 - 12,214,656 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034797533 (Get FASTA)   NCBI Sequence Viewer  
  XP_034797534 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000027731.1
Reference Protein Sequences
RefSeq Acc Id: XP_034797533   ⟸   XM_034941642
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034797534   ⟸   XM_034941643
- Peptide Label: isoform X2
RefSeq Acc Id: ENSPPAP00000027731   ⟸   ENSPPAT00000050574
Protein Domains
C2   PI-PLC Y-box


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000036929 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000050574.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/TrEMBL
  PLC-delta3_EF-hand UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/TrEMBL
NCBI Gene PLCD3 ENTREZGENE
PANTHER PTHR10336 UniProtKB/TrEMBL
  PTHR10336:SF33 UniProtKB/TrEMBL
Pfam EF-hand_10 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/TrEMBL
  PIPLC_Y_DOMAIN UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLCXc UniProtKB/TrEMBL
  PLCYc UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
  SSF49562 UniProtKB/TrEMBL
  SSF51695 UniProtKB/TrEMBL
UniProt A0A2R9BHH6_PANPA UniProtKB/TrEMBL